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Reyhan Polat et al.
Middle East journal of anaesthesiology, 21(5), 673-677 (2012-12-26)
Propofol injection pain is a frequent and a well-known complaint distressing for the patients. Although the ethiology of this pain remains obscure, the ideal method for the prevention of propofol injection pain is still controversial. Local anesthetics, opioids, nonsteroidal anti-inflammatory
Xiaoning Liu et al.
Chemosphere, 113, 146-150 (2014-07-30)
P loss during the fresh urine storage process is inevitable because of the presence of Ca and Mg. Dilution is one of the most important parameters influencing urine composition and subsequent P recovery. This study aimed to investigate the fate
Ling Lv et al.
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 23(3), 195-198 (2005-08-30)
To study the relationship between genetic polymorphism of tumor necrosis factor-alpha (TNF-alpha, sites at -238 nt and -308 nt) and susceptibility to chronic benzene poisoning. The polymorphism of TNF-alpha gene were detected by nested polymerase chain reaction-restriction fragment length polymorphism
P Opfermann et al.
Clinical and experimental immunology, 180(1), 131-142 (2014-11-18)
Reparixin, a CXCR 1/2 antagonist, has been shown to mitigate ischaemia-reperfusion injury (IRI) in various organ systems in animals, but data in humans are scarce. The aim of this double-blinded, placebo-controlled pilot study was to evaluate the safety and efficacy
F Megiorni et al.
The British journal of dermatology, 165(4), 823-827 (2011-06-23)
Alopecia areata (AA) is a multifactorial disease characterized by hair loss especially from the scalp. As for other autoimmune conditions, the major histocompatibility complex (HLA) region is associated with AA susceptibility. To provide evidence for the association of specific HLA-DQB1
Sophia S Wang et al.
Human genetics, 122(1), 41-49 (2007-05-15)
Catechol-O-methyltransferase (COMT) is an important modulator in the catabolism of extraneural dopamine, which plays an important role in drug reward mechanisms. It is hypothesized that genetic variations in the COMT gene, which can result in a three to fourfold difference
James R Conner et al.
Cancer cytopathology, 123(5), 298-305 (2015-03-06)
Morphologic overlap between renal oncocytoma (RO) and chromophobe renal cell carcinoma (ChRCC) can pose diagnostic challenges, especially in biopsy samples in which tumor quantity may be limited, architectural features are not well represented, and gross examination is not possible. It
Astrid Baalbergen et al.
International journal of cancer, 121(1), 106-110 (2007-03-14)
We investigated the significance of prognostic markers-estrogen receptor, progesterone receptor, p53, MIB-1 and bcl-2 - in adenocarcinoma of the uterine cervix. In 101 patients with primary cervical adenocarcinoma, treated from 1989 to 2000, we evaluated clinical parameters in relation to
Aydeniz Demir et al.
Environmental technology, 34(5-8), 799-805 (2013-07-11)
A two-step method for the remediation of three different types of lead (Pb)-contaminated soil was evaluated. The first step included soil washing with ethylenediaminetetraacetic acid (EDTA) to remove Pb from soils. The washing experiments were performed with 0.05 M Na2EDTA
Claudine Angela Blum et al.
Lancet (London, England), 385(9977), 1511-1518 (2015-01-23)
Clinical trials yielded conflicting data about the benefit of adding systemic corticosteroids for treatment of community-acquired pneumonia. We assessed whether short-term corticosteroid treatment reduces time to clinical stability in patients admitted to hospital for community-acquired pneumonia. In this double-blind, multicentre
Jin-Ping Lai et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 25(6), 854-858 (2012-03-06)
A promising targeted therapy against NY-ESO-1 (CTAG 1B) using genetically modified T-cells in synovial sarcomas was recently demonstrated in a clinical trial at the NCI. To investigate the role of NY-ESO-1 immunohistochemistry in patient selection and gain better insight into
Guang-Hui Wang et al.
Oncology letters, 5(2), 544-548 (2013-02-20)
In our previous study, significantly high expression levels of matrix-remodeling associated 5 (MXRA5) were identified in fresh-cultured colorectal cancer (CRC) tissues compared with their normal adjacent mucosa by differential secretome analysis. Whether MXRA5 is a potential serum biomarker of CRC
Marcia S Brose et al.
Lancet (London, England), 384(9940), 319-328 (2014-04-29)
Patients with radioactive iodine ((131)I)-refractory locally advanced or metastatic differentiated thyroid cancer have a poor prognosis because of the absence of effective treatment options. In this study, we assessed the efficacy and safety of orally administered sorafenib in the treatment
Lauren E McLemore et al.
Applied immunohistochemistry & molecular morphology : AIMM, 26(9), 611-619 (2017-04-20)
Response to neoadjuvant chemotherapy (NAC) in invasive breast cancer (IBC) is partly regulated by the immune microenvironment. We evaluated immune checkpoint PD-L1 expression, presence of CD68+ cells of macrophage/monocytic lineage and stromal tumor-infiltrating lymphocytes (TILs) in prechemotherapy biopsies and correlated
Briete Goorts et al.
Breast cancer research : BCR, 20(1), 34-34 (2018-04-20)
The main purpose was to investigate the correlation between magnetic resonance imaging (MRI)-based response patterns halfway through neoadjuvant chemotherapy and immunotherapy (NAC) and pathological tumor response in patients with breast cancer. Secondary purposes were to compare the predictive value of
Magdalena Ignaszak-Szczepaniak et al.
Oncology reports, 16(1), 65-71 (2006-06-21)
The TP53 polymorphism occurs at codon 72 of exon 4 with two alleles encoding either arginine or proline. The association between this common polymorphism and risk of different cancers has been extensive studied, however various reports are controversial. We have
Min Jung Kim et al.
Theriogenology, 84(7), 1256-1261 (2015-08-12)
Although dog cloning technology has been applied to conservation of endangered canids, propagation of elite dogs, and production of transgenic dogs, the efficiency of cloning is still very low. To help overcome this problem, we evaluated the effect of treating
Carmen Ungureanu et al.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 51(3), 497-503 (2010-09-03)
Genital HPV infections are extremely common but most of them are spontaneously cleared by the host immune response. The main problem is how to identify the HPV-HR positive patients who are at risk of progressive disease. The purpose of this
Lindsey Oudijk et al.
The Journal of clinical endocrinology and metabolism, 99(7), E1376-E1380 (2014-04-02)
Somatic or germline mutations in up to 15 disease-causative genes are detectable in up to 50% of patients with pheochromocytoma (PCC) and paraganglioma (PGL). Very recently, somatic H-RAS mutations were identified by exome sequencing in approximately 7% in sporadic PCCs
Ali Cihan Taskin et al.
In vitro cellular & developmental biology. Animal, 55(7), 473-481 (2019-06-20)
Leptin, a metabolic hormone, regulates the reproductive functions responding to both nutritional and body conditions. Embryonic stem cells play important roles in reproductive technology, but their derivation can be challenging. In this study, we evaluated the derivation rates of mouse
F T Cannizzo et al.
The Veterinary record, 163(15), 448-452 (2008-10-14)
Three groups of 10 veal calves were treated, respectively, with 5 mg of dexamethasone-21-isonicotinate administered intramuscularly on days 0 and 7 (group A); 0.4 mg/day of dexamethasone-21-phosphate administered orally for 20 days (group B); or left untreated as controls (group
R W Neumar et al.
Journal of neurochemistry, 66(1), 421-424 (1996-01-01)
Proteolytic degradation of numerous calpain substrates, including cytoskeletal and regulatory proteins, has been observed during brain ischemia and reperfusion. In addition, calpain inhibitors have been shown to decrease degradation of these proteins and decrease postischemic neuronal death. Although these observations
Sally N Adebamowo et al.
International journal of stroke : official journal of the International Stroke Society, 10(7), 1093-1100 (2015-06-06)
Intakes of magnesium, potassium, and calcium have been inversely associated with the incidence of hypertension, a known risk factor for stroke. However, only a few studies have examined intakes of these cations in relation to risk of stroke. The aim
Jing-li DU et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 40(1), 11-16 (2011-03-25)
To study the expression and significance of GPC3, CD10 and CD34 in hepatocellular carcinoma (HCC), dysplastic nodules (DN), cirrhotic regenerative nodules (CRN), focal nodular hyperplasia (FNH) and hepatocellular adenoma (HA). Immunohistochemical study for GPC3, CD10, CD34 and AFP was performed
Arie Perry et al.
Journal of neuropathology and experimental neurology, 61(8), 702-709 (2002-08-03)
Malignant peripheral nerve sheath tumors (MPNSTs) are diagnostically challenging neoplasms for which sensitive and specific immunohistochemical markers are lacking. Although limited to date, previous studies have suggested that NF1 (17q), NF2 (22q), p16 (9p), and EGFR (7p) alterations may be
L D Koller et al.
Toxicologic pathology, 13(1), 50-57 (1985-01-01)
Sprague-Dawley rats were exposed to 0, 26, or 2600 ppm lead as lead acetate in drinking water for 76 weeks. At 28 weeks of lead exposure, a portion of each group was exposed simultaneously to 6.36 g/kg ethyl urea (EU)
Masaya Kawaguchi et al.
European journal of radiology, 132, 109212-109212 (2020-09-27)
This study aimed to assess the efficacy of using MR imaging findings for differentiating cutaneous malignant melanoma (cMM) from cutaneous squamous cell carcinoma (cSCC). Preoperative MR images of patients with histopathologically proven primary cMM and primary cSCC were retrospectively reviewed
B Ståhlbom et al.
International archives of occupational and environmental health, 70(6), 393-398 (1997-01-01)
The aim of the present study was to develop a method for generation of dimethylbenzylamine (DMBA) atmospheres in an exposure chamber and to investigate the possibility of using urinary DMBA metabolites for biological monitoring of exposure to DMBA. A DMBA
Amarapurkar Deepak et al.
Tropical gastroenterology : official journal of the Digestive Diseases Foundation, 32(4), 279-284 (2012-06-16)
Myeloproliferative disorders (MPD) (like polycythemia vera, essential thrombocythemia and primary myelofibrosis) are responsible for 50% cases of Budd-Chiari syndrome (BCS) and 35% cases of portal venous thrombosis (PVT) in western series. A point mutation at Val617Phe of Janus kinase 2
Nicholas E Burjek et al.
Critical care medicine, 42(5), 1204-1212 (2013-12-25)
To test the hypothesis that low bispectral index scores and low sedative requirements during therapeutic hypothermia predict poor neurologic outcome. Observational study of a prospectively collected cohort. Cardiovascular ICU. One hundred sixty consecutive cardiac arrest patients treated with therapeutic hypothermia.
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