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关键词:'500-73-2'
显示 1-30 共 33 条结果 关于 "500-73-2" 范围 论文
Won-Bo Shim et al.
Journal of agricultural and food chemistry, 57(3), 791-796 (2009-01-15)
A fluorescence polarization immunoassay (FPIA) for the quantitative determination of 6-chloronicotinic acid (6-CNA) using polyclonal antibody was developed. The 6-CNA-protein (bovine serum albumin and soybean trypsin inhibitor) conjugates and fluorescein-labeled 6-CNA derivative (tracer) were prepared and used as the immunogens
A A Scott-Van Zeeland et al.
Molecular psychiatry, 19(6), 724-732 (2013-09-04)
Anorexia nervosa (AN) and related eating disorders are complex, multifactorial neuropsychiatric conditions with likely rare and common genetic and environmental determinants. To identify genetic variants associated with AN, we pursued a series of sequencing and genotyping studies focusing on the
Aimée E van Dijk et al.
Diabetes care, 32(6), 1023-1025 (2009-03-28)
Coffee consumption has been associated with lower risk of type 2 diabetes. We evaluated the acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on glucose tolerance. We conducted a randomized crossover trial of the
Lukman Bola Abdulra'uf et al.
Food chemistry, 177, 267-273 (2015-02-11)
An HS-SPME method was developed using multivariate experimental designs, which was conducted in two stages. The significance of each factor was estimated using the Plackett-Burman (P-B) design, for the identification of significant factors, followed by the optimization of the significant
Zia Shariat-Madar et al.
The Journal of biological chemistry, 277(20), 17962-17969 (2002-02-07)
Our recent investigations have postulated a human umbilical vein endothelial cell (HUVEC)-associated prekallikrein activator (PKA). When prekallikrein (PK) assembles on high molecular weight kininogen on HUVEC, PK is activated to kallikrein. PKA was found in the 15,800 x g pellet
Shu-Ying Chang et al.
Drug metabolism and disposition: the biological fate of chemicals, 36(12), 2513-2522 (2008-09-13)
Various groups have sought to determine the impact of CYP2C8 genotype (and CYP2C8 inhibition) on the pharmacokinetics (PK) of ibuprofen (IBU) enantiomers. However, the contribution of cytochrome P450 2C8 (CYP2C8) in human liver microsomes (HLMs) has not been reported. Therefore
Harold E Bays et al.
The American journal of cardiology, 108(5), 682-690 (2011-06-21)
AMR101 is an omega-3 fatty acid agent containing ≥96% eicosapentaenoic acid ethyl ester and no docosahexaenoic acid. Previous smaller studies suggested that highly purified eicosapentaenoic acid lowered triglyceride (TG) levels without increasing low-density lipoprotein (LDL) cholesterol levels. TG-lowering therapies such
Hilkka Ylihärsilä et al.
Journal of hypertension, 22(7), 1283-1287 (2004-06-18)
The combination of small birth size and the Pro12Pro variant of the peroxisome proliferator-activated receptor-gamma 2 (PPAR-gamma 2) gene has been shown to be associated with insulin resistance, which is linked to hypertension. We examined whether the association between small
Suresh Kumar Gorla et al.
Journal of medicinal chemistry, 56(10), 4028-4043 (2013-05-15)
Cryptosporidium parvum is an enteric protozoan parasite that has emerged as a major cause of diarrhea, malnutrition, and gastroenteritis and poses a potential bioterrorism threat. C. parvum synthesizes guanine nucleotides from host adenosine in a streamlined pathway that relies on
Ramakrishna Nirogi et al.
Biomedical chromatography : BMC, 25(12), 1319-1326 (2011-02-11)
A sensitive high-performance liquid chromatography-positive ion electrospray tandem mass spectrometry method was developed and validated for the quantification of urapidil in plasma. Following liquid-liquid extraction, the analyte was separated using an isocratic mobile phase on a reverse-phase column and analyzed
S I Hu et al.
Biochemistry, 25(24), 7834-7839 (1986-12-02)
C-reactive protein (CRP), an acute-phase plasma protein of hepatic origin in man and rabbit, is a cyclic pentamer composed of five identical nonglycosylated Mr 22 500 subunits. We have isolated both cDNA and genomic clones for rabbit CRP. These clones
M C de Mello et al.
Neurochemistry international, 22(3), 249-253 (1993-03-01)
Cultured retina cells from chick embryos took up [3H]putrescine and approx 10.8% of the incorporated amine was converted into [3H]GABA. The putrescine-derived GABA accumulated in a pool that was released in the medium at a rate corresponding to 3.66% of
Eugene J Teoh et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 56(9), 1447-1452 (2015-07-15)
Q.Clear, a Bayesian penalized-likelihood reconstruction algorithm for PET, was recently introduced by GE Healthcare on their PET scanners to improve clinical image quality and quantification. In this work, we determined the optimum penalization factor (beta) for clinical use of Q.Clear
Ioannis G Habeos et al.
Hormones (Athens, Greece), 2(1), 55-60 (2006-09-28)
Several authors have suggested a positive association between diabetes type 2 (DM2) and the C282Y and H63D mutations of the hereditary hemochromatosis gene but others have disputed it. There are also papers reporting an increased iron load in diabetes type
Ze-Dong Wang et al.
The lancet. HIV, 4(4), e177-e188 (2017-02-06)
Worldwide, 30% of the world's population have antibodies to the intracellular protozoan parasite Toxoplasma gondii and about 36·7 million people are infected with HIV, but little is known about the prevalence of co-infection with T gondii and HIV. We aimed
R C Sills et al.
Carcinogenesis, 25(4), 605-612 (2003-12-23)
In the previous 500 2-year chemical bioassays within the National Toxicology Program, large intestinal tumors (cecal carcinomas) related to chemical exposure have not been observed in B6C3F1 mice. The recently completed o-nitrotoluene study provided the first cecal tumor response and
Robert S Ackatia-Armah et al.
The American journal of clinical nutrition, 101(3), 632-645 (2015-03-04)
Moderate acute malnutrition (MAM), defined as weight-for-length z score between -3 and -2 or midupper arm circumference between 11.5 and 12.5 cm, affects ∼33 million children aged <5 y worldwide. The objective was to compare the effects of 4 dietary
G A Pankey
Clinical pharmacokinetics, 16 Suppl 1, 46-51 (1989-01-01)
Enoxacin achieves a high penetration into skin tissue and blister fluid, reaching a maximum serum concentration (Cmax) of 3.7 mg/L at a time to reach maximum concentration (tmax) of 1.9 hours and a blister-fluid Cmax of 2.9 mg/L at a
G Tapia et al.
The Journal of infection, 75(6), 555-571 (2017-09-18)
The REDUC clinical study Part B investigated Vacc-4x/rhuGM-CSF therapeutic vaccination prior to HIV latency reversal using romidepsin. The main finding was a statistically significant reduction from baseline in viral reservoir measurements. Here we evaluated HIV-specific functional T-cell responses following Vacc-4x/rhuGM-CSF
Ying Zhang et al.
Journal of separation science (2018-05-16)
An ultra high-performance liquid chromatography with tandem triple quadrupole mass spectrometry residue method was developed and validated for the quantification and identification of dinotefuran and its main metabolites 1-methyl-3-(tetrahydro-3-furylmethyl) urea and 1-methyl-3-(tetrahydro-3-furylmethyl) guanidine in fruit (watermelon), vegetable (cucumber), cereal (rice)
Ying Zhang et al.
Journal of separation science (2018-05-16)
An ultra high-performance liquid chromatography with tandem triple quadrupole mass spectrometry residue method was developed and validated for the quantification and identification of dinotefuran and its main metabolites 1-methyl-3-(tetrahydro-3-furylmethyl) urea and 1-methyl-3-(tetrahydro-3-furylmethyl) guanidine in fruit (watermelon), vegetable (cucumber), cereal (rice)
Kirsten E Bell et al.
PloS one, 12(7), e0181387-e0181387 (2017-07-19)
Protein and other compounds can exert anabolic effects on skeletal muscle, particularly in conjunction with exercise. The objective of this study was to evaluate the efficacy of twice daily consumption of a protein-based, multi-ingredient nutritional supplement to increase strength and
R C Hapak et al.
The Journal of biological chemistry, 269(7), 5288-5296 (1994-02-18)
CPV3 is a novel avian parvalbumin. It displays an isoelectric point of 4.6, intermediate between that of avian thymic hormone (pI = 4.3) and the muscle parvalbumin isoform (pI = 5.2). Expression of CPV3, like that of avian thymic hormone
F Mainferme et al.
European journal of biochemistry, 153(1), 211-216 (1985-11-15)
The synthesis, transport and processing of cathepsin C was studied in Morris hepatoma 7777 cells by metabolic labelling, immunoprecipitation and characterization of labelled polypeptides by gel electrophoresis and fluorography. The largest detectable precursor of cathepsin C was a polypeptide of
Yun Oh et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 26(7), 1135-1141 (2008-03-04)
Enzastaurin, an oral serine/threonine kinase inhibitor, suppresses protein kinase C (PKC) and protein kinase B/AK transforming (AKT) signaling, induces tumor cell apoptosis, and inhibits proliferation and angiogenesis. Increased PKC and AKT activity is associated with poor prognosis in non-small-cell lung
C Huxley et al.
Molecular and cellular biology, 10(2), 605-614 (1990-02-01)
The clustered arrangement (no two adjacent genes are separated by more than 73 base pairs [bp] and two genes overlap by 133 bp at their 3' ends) of the four genes (Surf-1 to -4) identified so far in the mouse
Mohammad Perwaiz Iqbal et al.
Pakistan journal of pharmaceutical sciences, 27(2), 245-248 (2014-03-01)
Low doses of granulocyte- colony stimulating factor (G-CSF) and granulocyte macrophage- colony stimulating factor (GM-CSF) have been shown to be beneficial in reducing duration of systemic antibiotic therapy and in-patient hospitalization by decreasing the period of neutropenia in cancer patients
Mark S Sulkowski et al.
JAMA, 312(4), 353-361 (2014-07-20)
Treatment of hepatitis C virus (HCV) infection in patients also infected with human immunodeficiency virus (HIV) has been limited due to drug interactions with antiretroviral therapies (ARTs) and the need to use interferon. To determine the rates of HCV eradication
R G Clark et al.
Endocrinology, 138(10), 4316-4323 (1997-10-10)
Besides stimulating GH release, some GH secretagogues also release ACTH and adrenal steroids. Several novel classes of potent GH secretagogues have recently been described, and we have now tested their ability to release corticosterone in conscious normal rats. All analogs
Tim Snijders et al.
The Journal of nutrition, 148(6), 891-899 (2018-06-08)
Nutritional supplementation can have beneficial effects on body composition, strength, and function in older adults. However, whether the response of satellite cells can be altered by nutritional supplementation in older adults remains unknown. We assessed whether a multi-ingredient protein-based supplement
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