527-52-6

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Protective effect of EX-527 against high-fat diet-induced diabetic nephropathy in Zucker rats.

Amit Kundu et al.

Toxicology and applied pharmacology, 390, 114899-114899 (2020-01-26)

High-fat diet (HFD)-induced obesity is implicated in diabetic nephropathy (DN). EX-527, a selective Sirtuin 1 (SIRT1) inhibitor, has multiple biological functions; however, its protective effect against DN is yet to be properly understood. This study was aimed to explore the

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