534-13-4

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Contribution of hydrophobic interactions to protein stability.

C Nick Pace et al.

Journal of molecular biology, 408(3), 514-528 (2011-03-08)

Our goal was to gain a better understanding of the contribution of hydrophobic interactions to protein stability. We measured the change in conformational stability, Δ(ΔG), for hydrophobic mutants of four proteins: villin headpiece subdomain (VHP) with 36 residues, a surface

Collapsing glomerulopathy superimposed on diabetic nephropathy: insights into etiology of an under-recognized, severe pattern of glomerular injury.

Steven P Salvatore et al.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 29(2), 392-399 (2013-10-02)

Collapsing glomerulopathy (CG) represents severe podocyte injury with massive proteinuria, rapid progression and relative resistance to therapy. It is associated with multiple etiologies, including obliterative arteriopathy in transplants. However, its association with diabetic nephropathy (DN) has not been reported. Renal

Soluble gp130 is up-regulated in the implantation window and shows altered secretion in patients with primary unexplained infertility.

J R A Sherwin et al.

The Journal of clinical endocrinology and metabolism, 87(8), 3953-3960 (2002-08-06)

Members of the IL-6 family of cytokines, which includes leukemia inhibitory factor (LIF) and IL-11, play important roles in implantation. The activity of these cytokines is modified by soluble receptors such as the IL-6 receptor (sIL-6R). gp130 is a signal

Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model.

Jaime R Merchan et al.

Journal of the National Cancer Institute, 98(11), 756-764 (2006-06-08)

We and others have previously shown that plasminogen activators generate endogenous angiogenesis inhibitors and induce antiangiogenic activity. Here we assessed the effects of plasminogen activator overexpression on tumor progression in a syngeneic mammary cancer model. Genes encoding murine tissue plasminogen

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