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Jennifer Pors et al.
Applied immunohistochemistry & molecular morphology : AIMM, 28(8), 593-601 (2019-07-31)
Mesonephric carcinoma is a rare gynecologic neoplasm commonly mistaken for clear cell carcinoma, because of their overlapping morphologic features. Both tumors are negative for estrogen receptor and p16, magnifying this diagnostic dilemma. Recently, hepatocyte nuclear factor-1 beta (HNF-1β), a marker
Femke Rutters et al.
Clinical endocrinology, 74(6), 679-686 (2011-04-28)
The relationship between hypothalamus/pituitary/adrenal (HPA) axis functioning and (visceral) obesity may be explained by single-nucleotide polymorphisms (SNPs) of the HPA axis. Objective  To investigate the relationship between the HPA axis SNP's 'BclI' in the glucocorticoid receptor gene and C8246T in
S Sood et al.
Theriogenology, 78(7), 1557-1569 (2012-09-18)
Three experiments were conducted to optimize the protocol for cryopreservation of emu sperm. Ejaculates were collected from trained male emus then diluted 1:1 and pooled before allocation to treatments and measured for sperm viability, motility, egg membrane penetration ability, membrane
Maheshi N Ramasamy et al.
Lancet (London, England), 396(10267), 1979-1993 (2020-11-23)
Older adults (aged ≥70 years) are at increased risk of severe disease and death if they develop COVID-19 and are therefore a priority for immunisation should an efficacious vaccine be developed. Immunogenicity of vaccines is often worse in older adults
Renata Cristina Mazon et al.
Acta histochemica, 113(2), 109-116 (2009-10-09)
Since the role of human papillomavirus (HPV) infection in oral carcinogenesis is still unclear, the purpose of this study was to verify the association between the expression of p27, mdm2 and cathepsin B and by HPV-related oral lesions. Fifty-five oral
Hong-cui Fan et al.
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 25(3), 222-225 (2009-03-05)
To explore the therapeutic effectivity and the possible mechanism of triptolide (Tri) on experimental autoimmune encephalomyelitis (EAE). All female C57BL/6 mice were randomly divided into EAE group (28), Tri treated group (20) and adjuvant group (18). Mice in EAE and
G Massarweh et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 67(11), 2040-2043 (2009-08-21)
[(18)F]Altanserin, an important PET radioligand for the in vivo imaging of the 5-HT(2A) receptor, was synthesized from its precursor nitro-altanserin in DMF or DMSO at high temperatures of 150 degrees C in an overall radiochemical yield (EOB) of 23-25% after
R Gonzalo-Lumbreras et al.
Journal of pharmaceutical and biomedical analysis, 31(1), 201-208 (2003-02-01)
Two isocratic liquid chromatographic methods (conventional and micellar) for the determination of methyltestosterone in sugar-coated pills using fluoxymesterone as internal standard have been developed and validated. In conventional liquid chromatography a mobile phase 45% water:acetonitrile 55% (v:v), a flow-rate 1
Leonie Calver et al.
The American journal of emergency medicine, 31(6), 970-973 (2013-05-21)
This study aimed to investigate sedation of elderly patients with acute behavioral disturbance (ABD) in the emergency department (ED), specifically the safety and effectiveness of droperidol. This was a prospective study of elderly patients (>65 years) with ABD requiring parenteral
Monideepa Baruah et al.
The Journal of reproductive medicine, 53(3), 203-206 (2008-04-30)
To assess the efficacy of rectal misoprostol as second-line therapy in the management of primary postpartum hemorrhage (PPH) as compared to methylergonovine maleate. This was a retrospective cohort study. Charts from July 2000 to February 2005 were reviewed. Inclusion criteria
Shabih U Hasan et al.
JAMA pediatrics, 171(11), 1081-1089 (2017-10-04)
Bronchopulmonary dysplasia (BPD) occurs in approximately 40% of infants born at younger than 30 weeks' gestation and is associated with adverse pulmonary and neurodevelopmental outcomes. To test whether administration of inhaled nitric oxide to preterm infants requiring positive pressure respiratory
Yee-Jee Jan et al.
Human pathology, 40(10), 1384-1390 (2009-05-21)
Focal adhesion kinase plays a critical role in cancer progression, invasion, and metastasis. Although focal adhesion kinase overexpression indicates poor prognoses for hepatocellular carcinoma, its role in hepatocellular carcinoma metastasis has not been well investigated. In this study, 55 hepatocellular
Hilda B. ten Brink et al.
Inorganic chemistry, 37(26), 6780-6784 (2001-10-24)
Vanadium haloperoxidases catalyze the oxidation of halides by hydrogen peroxide to produce hypohalous acid. We demonstrate that these enzymes also slowly mediate the enantioselective oxidation of organic sulfides (methyl phenyl sulfide, methyl p-tolyl sulfide, and 1-methoxy-4 (methylthio)benzene) to the corresponding
Satu Wedenoja et al.
Human mutation, 32(7), 715-722 (2011-03-12)
Congenital chloride diarrhea (CLD) is an autosomal recessive disorder with around 250 cases reported so far. Life-long secretory diarrhea is caused by mutations in the solute carrier family 26 member 3 (SLC26A3) gene disrupting the epithelial Cl(-) /HCO 3- transport
J Harsfalvi et al.
Biochimica et biophysica acta, 1073(2), 268-274 (1991-03-04)
Exhaustive extraction of human platelets with 6 M guanidine-HCl, and 5% beta-mercaptoethanol, followed by 5% SDS resulted in a sedimentable material which showed fibrous structure by transmission electron microscopy. When platelets treated with 8 M urea, 50 mM DTT and
Da Eun Lee et al.
PloS one, 8(11), e78136-e78136 (2013-11-14)
Quantification of cell-free fetal DNA by methylation-based DNA discrimination has been used in non-invasive prenatal testing of fetal chromosomal aneuploidy. The maspin (Serpin peptidase inhibitor, clade B (ovalbumin), member 5; SERPINB5) gene, located on chromosome 18q21.33, is hypomethylated in the
T S Wu et al.
Bioorganic & medicinal chemistry, 9(1), 77-83 (2001-02-24)
Five new constituents including a flavonoid, artemisidin A (1), and four coumarins, artemicapins A (2), B (3), C (4) and D (5), together with 70 known compounds (6-75), have been isolated and characterized from the aerial part of Artemisia capillaris.
Yun Cui et al.
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 20(3), 200-202 (2003-06-05)
To investigate the mutation spectrum of phosphodiesterase beta subunit (PDE6B) gene and incidence in Chinese retinitis pigmentosa (RP) patients. Genomic DNA was extracted from the blood samples of 38 patients from 35 autosomal recessive retinitis pigmentosa (ARRP) families and 55
V Horejsí et al.
Folia biologica, 34(1), 23-34 (1988-01-01)
The specificities of several monoclonal antibodies described by us earlier were determined more exactly: (1) antibodies MEM-31 and MEM-32 are directed against CD8 and CD5 T cell antigens, respectively: (2) MEM-15 and MEM-18 react with the CD14 monocyte antigen; (3)
Przemysław Zalewski et al.
Chromatographia, 76(7-8), 387-391 (2013-04-05)
The stability-indicating LC assay method was developed and validated for quantitative determination of cefcapene pivoxil in the presence of degradation products formed during forced degradation studies. An isocratic RP-HPLC method was developed with a Lichrospher RP-18 (250 mm × 4.6 mm, 5 μm) column and
F M Nakhoul et al.
Diabetologia, 44(5), 602-604 (2001-05-31)
To determine if the haptoglobin 2 allele is associated with an increased risk for the development of diabetic nephropathy. This study included 110 consecutive normotensive subjects with Type I (insulin-dependent) diabetes mellitus and Type II (non-insulin-dependent) diabetes mellitus seen in
M Brien et al.
Placenta, 51, 82-88 (2017-03-16)
Preeclampsia (PE) was shown to affect the placental content and the transfer of polyunsaturated fatty acids (PUFA) to the fetus. Plasmalogens, a type of phospholipids with a vinyl-ether link at the sn-1 position, play an antioxidant role and are specifically
Brian P Adley et al.
Analytical and quantitative cytology and histology, 28(4), 228-236 (2006-08-25)
To investigate the diagnostic value of cytokeratin 7 (CK7) and parvalbumin at mRNA and protein levels. CK7 and parvalbumin mRNA expression levels in 23 oncocytomas and 32 chromophobe renal cell carcinomas (RCCs) were examined using gene expression microarrays. Immunohistochemistry was
J P Gromiec et al.
International archives of occupational and environmental health, 55(1), 61-72 (1984-01-01)
Absorption of ethylbenzene and excretion of mandelic acid were investigated under controlled conditions in six volunteers, exposed at concentrations of 18, 34, 80, and 200 mg/m3. Retention of ethylbenzene vapours in the lungs was 49 +/- 5%. Elimination of mandelic
Walter L Murfee et al.
Microcirculation (New York, N.Y. : 1994), 13(3), 261-273 (2006-04-22)
Recently the authors have shown that neuron-glial antigen 2 (NG2) is expressed by perivascular cells along arterioles and capillaries, but not along venules in quiescent rat mesenteric microvascular networks. To investigate how the spatial distribution of this proteoglycan changes during
P N Rizk et al.
Xenobiotica; the fate of foreign compounds in biological systems, 25(2), 143-150 (1995-02-01)
1. The oxidative metabolism of 4-iodoanisole (1) by liver microsomes from beta-naphthoflavone-treated rats yields 4-iodophenol (2) 2-iodo-5-methoxyphenol (3), 2-methoxy-5-iodophenol (4), 4-methoxyphenol (5), and 3-methoxyphenol (6) in relative yields of 5:2:4:1:1 respectively. 2. [3 5-2H2]-1 was converted to the same five
S Yanagi et al.
Journal of the National Cancer Institute, 73(4), 887-894 (1984-10-01)
A probably promoter-specific decrease of L-type pyruvate kinase (L-PK) in Wistar rat liver is described. The possibility of utilizing the decrease in L-PK activity for screening of hepatic promoters is discussed. A significantly decreased level of activity of L-PK was
S Raje et al.
Clinical pharmacology and therapeutics, 83(1), 86-96 (2007-05-18)
This positron emission tomography (PET) study was conducted to assess binding of lecozotan, a new potent and silent 5-hydroxytryptamine-1A (5-HT1A) antagonist being developed for the treatment of Alzheimer's disease (AD), to 5-HT1A receptors in the human brain using 11C-labeled WAY-100635.
Norbert Galldiks et al.
Neuro-oncology, 17(9), 1293-1300 (2015-05-27)
We evaluated the diagnostic value of static and dynamic O-(2-[(18)F]fluoroethyl)-L-tyrosine ((18)F-FET) PET parameters in patients with progressive or recurrent glioma. We retrospectively analyzed 132 dynamic (18)F-FET PET and conventional MRI scans of 124 glioma patients (primary World Health Organization grade
Huiying He et al.
Applied immunohistochemistry & molecular morphology : AIMM, 17(1), 40-46 (2008-09-25)
The pathologic diagnosis of Merkel cell carcinoma (MCC) is mainly based on routine morphology and a characteristic cytokeratin 20 (CK20) immunohistochemical staining pattern. However, about 10% to 15% of MCCs are reportedly CK20 negative and about 10% to 20% of
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