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P R Postma et al.
Bioresource technology, 203, 80-88 (2016-01-02)
The synergistic effect of temperature (25-65 °C) and total specific energy input (0.55-1.11 kWh kgDW(-1)) by pulsed electric field (PEF) on the release of intracellular components from the microalgae Chlorella vulgaris was studied. The combination of PEF with temperatures from
Zhiqun Zhang et al.
Journal of neurotrauma, 24(3), 460-472 (2007-04-04)
Collapsin response mediator proteins (CRMPs) are important molecules in neurite outgrowth and axonal guidance. Within the CRMP family, CRMP-2 has been implicated in several neurological diseases (Alzheimer's, epilepsy, and ischemia). Here, we investigated the integrity of CRMPs (CRMP-1, -2, -4
Lu Zhao et al.
Neuroscience letters, 716, 134633-134633 (2019-11-20)
Kaempferol is a medicinal flavonol derived from the roots of Kaempferia galanga L. Kaempferol can affect cell survival, apoptosis, and anti-oxidation, though its role and underlying mechanism in retinal ganglion cells with high-glucose injury remains unclear. In this study, we
Akihiro Michihara et al.
Biological & pharmaceutical bulletin, 33(9), 1471-1476 (2010-09-09)
In the present study, we investigated the dose-dependent effect of delta-tocotrienol long term (48, 72 h) on the melanin content of cells treated with delta-tocotrienol, and whether cells treated with delta-tocotrienol for long a time show cytotoxicity. We also examined
Simona Fecarotta et al.
Orphanet journal of rare diseases, 10, 22-22 (2015-04-19)
Twenty-five patients with Niemann Pick disease type C (age range: 7 months to 44 years) were enrolled in an Italian independent multicenter trial and treated with miglustat for periods from 48 to 96 months. Based on the age at onset of neurological manifestations
Rocco Salvatore Calabrò et al.
Neurology India, 57(5), 636-637 (2009-11-26)
Ischemic stroke is a complex multifactorial disease and approximately 30%, especially in the young, are cryptogenic. In some of the patients with cryptogenic ischemic stroke the underlying risk factor may be a prothrombotic state. We studied 101 patients with ischemic
K Vasudevan et al.
Laboratory animals, 46(4), 299-303 (2012-10-26)
The 129 mice are well recognized for their low fertility and it is speculated that this lack of fertility may be due to the oocyte condition. In this study we investigated superovulation regimens for the 129S1/SvImJ mouse strain to improve
Bo Peng et al.
Zhonghua nan ke xue = National journal of andrology, 17(9), 805-808 (2011-10-04)
To investigate the inhibition of the expression of steroid receptor coactivator-1 (SRC-1) in the LNCap cell line through RNA interference (RNAi) and the effect of the silenced SRC-1 gene on LNCap cells. The experiment included four groups: siRNA transfection, siRNA
Sumeet Khanduja et al.
Journal of glaucoma, 24(4), 267-271 (2013-01-23)
To evaluate the change in anterior chamber angle parameters after scleral buckling surgery using anterior segment optical coherence tomography (ASOCT). Fifty-five phakic eyes of 55 subjects undergoing scleral buckling with the placement of an encircling band for primary rhegmatogenous retinal
Zhong-Yue Xiao et al.
Asian Pacific journal of cancer prevention : APJCP, 13(1), 247-250 (2012-04-17)
To determine whether CDX2 and villin protein expression are associated with intestinal metaplasia (IM) in gastric cardiac mucosa and to explore the relationship with evolution of gastric cardiac adenocarcinoma (GCA). We studied 143 gastric cardiac biopsy or resection specimens from
Satyendra Kumar et al.
Protein expression and purification, 41(1), 38-44 (2005-04-02)
A thermophilic isolate Bacillus coagulans BTS-3 produced an extracellular alkaline lipase, the production of which was substantially enhanced when the type of carbon source, nitrogen source, and the initial pH of culture medium were consecutively optimized. Lipase activity 1.16 U/ml
M Peces et al.
Bioresource technology, 200, 631-638 (2015-11-10)
There is a growing trend to consider organic wastes as potential sources of renewable energy and value-add products. Fermentation products have emerged as attractive value-add option due to relative easy production and broad application range. However, pre-fermentation and extraction of
K Krohn et al.
Lancet (London, England), 339(8796), 770-773 (1992-03-28)
Idiopathic Addison's disease is characterised by a progressive failure in the synthesis of all classes of steroid hormones and by an immune response against the steroid-producing cells of the adrenal cortex; the nature of the adrenal autoantigens is not known.
S Regnér et al.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 8(6), 600-607 (2008-10-14)
The pathophysiology of acute pancreatitis (AP) may be studied using markers of protease activation (active carboxypeptidase B (aCAP), the activation peptide of carboxypeptidase B (CAPAP)), leakage of pancreatic enzymes (trypsinogen-2, procarboxypeptidase B (proCAP), amylase), and inflammation (monocyte chemoattractant protein-1 (MCP-1)
Yun-Qing Bai et al.
Cancer letters, 176(1), 47-55 (2002-01-16)
The roles of CDX2 and CDX1 homeobox genes during gastric carcinogenesis remain poorly defined. We have studied the expression of CDX2/1 in gastric cancers and intestinal metaplasia (IM) of 69 gastric carcinoma patients by immunohistochemistry. CDX2/1 were shown to be
Raed Salim et al.
Obstetrics and gynecology, 120(6), 1323-1331 (2012-11-22)
To compare the tocolytic efficacy and tolerability of nifedipine with that of atosiban among pregnant women with preterm labor. Pregnant women admitted with preterm labor and intact membranes between 24 and 33 weeks 6 days of gestation, between January 2008
R Pérez-Gálvez et al.
Food & function, 7(9), 3890-3901 (2016-08-17)
Fish protein hydrolysates from Mediterranean horse mackerel were produced by using a mixture of two commercial endoproteases (i.e. subtilisin and trypsin) at different levels of substrate concentration (2.5 g L(-1), 5 g L(-1), and 7.5 g L(-1) of protein), temperature
Ayda Pouyafar et al.
Journal of cellular biochemistry (2019-01-05)
Ovarian cancer is associated with a high percentage of recurrence of tumor and resistance to chemotherapy. Cancer stem cells (CSCs) form a rare population with a significant capacity to begin and expand malignant diseases. Eliminating the drug resistance of CSCs
K T Rogers et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(15), 7594-7599 (1996-07-23)
E2F is a heterodimeric transcription factor that regulates the expression of genes at the G1/S boundary and is composed of two related but distinct families of proteins, E2F and DP. E2F/DP heterodimers form complexes with the retinoblastoma (Rb) protein, the
Feras M Hantash et al.
Genetics in medicine : official journal of the American College of Medical Genetics, 13(1), 39-45 (2010-12-01)
Fragile X syndrome is caused by expansion and methylation of a CGG tract in the 5' untranslated region of the FMR1 gene. The estimated frequency of expanded alleles (≥55 repeats) in the United States is 1:257-1:382, but these estimates were
Jose Luis Lopez-Campos et al.
Biomarkers in medicine, 6(6), 805-811 (2012-12-12)
Serum ICAM-1 (sICAM-1) is known to be a smoking-associated inflammatory marker, but data in chronic obstructive pulmonary disease (COPD) are lacking. A total of 142 COPD cases (48 active smokers) and 55 controls (41 active smokers) were consecutively enrolled in
Annapurna Kumari et al.
Biotechnology for biofuels, 2(1), 1-1 (2009-01-16)
Transesterification of Jatropha oil was carried out in t-butanol solvent using immobilized lipase from Enterobacter aerogenes. The presence of t-butanol significantly reduced the negative effects caused by both methanol and glycerol. The effects of various reaction parameters on transesterification of
W McCanse et al.
Journal of applied physiology (Bethesda, Md. : 1985), 86(4), 1257-1263 (1999-04-08)
Systemic O2 transport during maximal exercise at different inspired PO2 (PIO2) values was studied in sodium cyanate-treated (CY) and nontreated (NT) rats. CY rats exhibited increased O2 affinity of Hb (exercise O2 half-saturation pressure of Hb = 27.5 vs. 42.5
Ayda Pouyafar et al.
Journal of cellular biochemistry (2019-01-05)
Ovarian cancer is associated with a high percentage of recurrence of tumor and resistance to chemotherapy. Cancer stem cells (CSCs) form a rare population with a significant capacity to begin and expand malignant diseases. Eliminating the drug resistance of CSCs
Mechanical strain induces a persistent upregulation of syndecan-1 expression in smooth muscle cells.
Matheau A Julien et al.
Journal of cellular physiology, 211(1), 167-173 (2006-12-07)
Syndecan-1 belongs to a family of transmembrane proteoglycans, acts as a coreceptor for growth factor binding, as well as cell-matrix and cell-cell interactions, and is induced in smooth muscle cells (SMCs) following balloon catheter injury. In this report, we investigated
Uriah Guevara-López et al.
Cirugia y cirujanos, 72(6), 483-490 (2005-02-08)
The analgesic efficacy of intramuscular etofenamate (1 g/day) and intramuscular diclofenac (75 mg/day) was assessed in post-surgical pain relief during a period of 3 days. One hundred ten hospitalized patients undergoing elective surgery were evaluated in an open-label, comparative, randomized
Nese Karaaslan Biyikli et al.
Pediatric nephrology (Berlin, Germany), 21(5), 649-654 (2006-03-28)
Human paraoxonase 1 (PON1) is a serum enzyme related to high-density lipoprotein which has a major role in preventing oxidative modification of low-density lipoprotein. Due to its amino acid substitution PON1 has two genetic polymorphisms. These polymorphisms are characterized by
Victor Z Chong et al.
Schizophrenia research, 100(1-3), 270-280 (2008-02-05)
Neuregulin-1 (NRG1) and its receptor, ErbB4, have been implicated in schizophrenia at both gene and transcript levels. The present investigation compared NRG1 and ErbB4 protein levels in prefrontal cortical (PFC) cytoplasmic and nuclear fractions among normal, schizophrenic, bipolar and major
Christian Kupatt et al.
Journal of leukocyte biology, 72(3), 455-461 (2002-09-12)
Leukocyte interaction with platelets and endothelial cells as cause of myocardial stunning was investigated. Mice were anesthetized and, after thoracotomy, the LAD was ligated for 20 min. Where indicated, rhodamine 6G for leukocyte labeling, fluorescence-labeled platelets, and the GPIIb/IIIa antagonist
Christian Praml et al.
Cancer letters, 272(1), 160-166 (2008-08-30)
AFAR genes play a key role in the detoxification of the carcinogen Aflatoxin B(1) (AFB(1)). In the rat, Afar1 induction can prevent AFB(1)-induced liver cancer. It has been proposed that AFAR enzymes can metabolise endogenous diketones and dialdehydes that may
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