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David Jamieson et al.
European journal of cancer (Oxford, England : 1990), 68, 1-10 (2016-10-04)
We performed a multi-centre phase I study to assess the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of the orally available small molecule mitogen-activated protein kinase kinase (MEK) 1/2 inhibitor, WX-554, and to determine the optimal biological dose for subsequent trials.
Mikkel Lundbech et al.
Thrombosis research, 186, 80-85 (2020-01-10)
Thrombin generation, thrombin-antithrombin complex (TAT) levels, and prothrombin fragment 1+2 (F1+2) have shown potential as biomarkers of thromboembolic risk. The aims were to establish reference intervals for these three biomarkers and to assess the levels in patients with localized cancer
Miguel Naveiras et al.
American journal of ophthalmology, 153(5), 958-966 (2012-01-31)
To describe the incidence and causes of glaucoma after Descemet membrane endothelial keratoplasty (DMEK). Nonrandomized prospective cohort study at a tertiary referral center. The incidence of glaucoma was evaluated in the first 275 consecutive eyes that underwent DMEK for Fuchs
Marvin Sinsakul et al.
Nephron. Clinical practice, 121(1-2), c25-c29 (2012-10-19)
A phase II open-label study was conducted in hemodialysis patients evaluating the short-term safety, tolerability, and iron absorption with ferric citrate when used as a phosphate binder. Enrollment occurred in two periods. Period 1 recruited patients taking 6-15 pills/day of
Jaeeun Yoo et al.
Archives of pathology & laboratory medicine, 143(8), 999-1005 (2019-02-15)
Infectious gastroenteritis is caused by various pathogens, including bacteria, viruses, and parasites. To compare the performance of Seegene Allplex Gastrointestinal (24 targets: 13 bacteria, 5 viruses, and 6 parasites in 4 panels), Luminex xTAG Gastrointestinal Pathogen Panel (15 targets: 9
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