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Samiran S Gauri et al.
Bioresource technology, 126, 350-353 (2012-11-07)
A comprehensive study was made on biotransformation of p-coumaric acid and 2,4-dichlorophenoxyacetic acid by an Azotobacter sp. strain SSB81. The strain was able to tolerate a high amount of both the phenolic acids and p-coumaric acid degraded maximum (50%) than
Serdar Karakurt et al.
Turkish journal of biology = Turk biyoloji dergisi, 44(5), 252-263 (2020-10-29)
Resistance to therapeutic agents and the highly toxic side effects of synthetic drugs has spurred new research in the treatment of colon cancer, which has high morbidity and mortality ratios. This study aims to clarify the molecular mechanisms of the
Yong Xue et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(26), 9449-9454 (2014-06-14)
p-Coumaric acid is the precursor of phenylpropanoids, which are plant secondary metabolites that are beneficial to human health. Tyrosine ammonia lyase catalyzes the production of p-coumaric acid from tyrosine. Because of their photosynthetic ability and biosynthetic versatility, cyanobacteria are promising
Katheryn M Goodrich et al.
Journal of agricultural and food chemistry, 62(46), 11190-11199 (2014-10-23)
Metabolism of flavanols (catechins, procyanidins) by gut microbiota has been extensively characterized. Comparatively little is known about accumulation of flavanols and their metabolites in the colon tissues, particularly during chronic exposure to low doses. Mice were fed low doses of
Aimin Shi et al.
PloS one, 9(10), e111188-e111188 (2014-10-28)
Although a number of bioactive peptides are capable of angiotensin I-converting enzyme (ACE) inhibitory effects, little is known regarding the mechanism of peanut peptides using molecular simulation. The aim of this study was to obtain ACE inhibiting peptide from peanut
Marcela Dendisova-Vyskovska et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 99, 196-204 (2012-10-16)
The detection of p-coumaric acid and ferulic acid using a combined in situ electrochemical and surface-enhanced Raman scattering spectroscopic technique in specially made electrode cell is described. New in situ spectroelectrochemical cell was designed as the three-electrode arrangement connected via
Shengbao Cai et al.
Journal of agricultural and food chemistry, 60(29), 7245-7251 (2012-07-07)
The purpose of the present work is to study the pancreatic lipase inhibitory effects of different subfractions (n-hexane, ethyl acetate (EA), n-butanol, and water) from ethanol extracts of nonfermented and fungi-fermented oats and to delineate the interactions of three primary
Abhro Jyoti Roy et al.
European journal of pharmacology, 699(1-3), 33-39 (2012-11-28)
The present study was designed to evaluate the preventive effects of p-coumaric acid on lysosomal dysfunction and myocardial infarct size in isoproterenol induced myocardial infarcted rats. Male albino Wistar rats were pretreated with p-coumaric acid (8 mg/kg body weight) daily
Taketoshi Hata et al.
PloS one, 7(11), e48072-e48072 (2012-11-08)
Brazilian green propolis is a popular health supplement because of its various biological properties. The ethanol extract of Brazilian green propolis (EEBP) is characteristic for its herb-like smell and unique pungent taste. However, the ingredients responsible for its pungency have
Fatih Mehmet Yılmaz et al.
Journal of food science and technology, 52(5), 2851-2859 (2015-04-22)
There is an increasing interest to bio-components obtained from fruit & vegetable wastes. Anthocyanin is one of the components regained from fruits especially from red ones. Sour cherry is considered as industrial fruit since most of the grown fruit is
A Morata et al.
Enzyme and microbial technology, 52(2), 99-104 (2013-01-01)
Hydroxycinnamate decarboxylase (HCDC) activity has been evaluated in several commercial yeast strains. The combined effect of using cinnamyl esterases (CE) and HCDC+ Saccharomyces cerevisiae strains has been studied in the formation of vinylphenolic pyranoanthocyanins (VPAs) during fermentation, analysing the kind
Wojciech Ostrowski et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 967, 21-27 (2014-07-27)
Liquid chromatography coupled to mass spectrometry (MS) with electrospray ionization (ESI) is one of analytical techniques to obtain accurate results of low molecular weight aromatic compounds in biological samples of different origin. The interpretations of mass spectra of these aromatic
Chang-Seob Seo et al.
Natural product communications, 8(10), 1443-1446 (2013-12-21)
Mori Cortex Radicis (MCR, Moraceae) is used traditionally in the treatment ofjaundice, hematemesis, edema, and pollakisuria in Korea. In this study, the antiinflammatory effects of MCR extract were investigated using RAW 264.7 cells. The simultaneous analysis of five components present
Mohammad Saraji et al.
Journal of chromatography. A, 1366, 24-30 (2014-09-28)
A magnesium-aluminum layered double hydroxide coated on magnetic nanoparticles was synthesized and used as a sorbent to extract some phenolic acids including p-hydroxy benzoic acid, caffeic acid, syringic acid, p-coumaric acid and ferulic acid from fruit juices. After extraction, the
Mattia Gasperotti et al.
Talanta, 128, 221-230 (2014-07-26)
An increasing number of studies have concerned the profiling of polyphenol microbial metabolites, especially in urine or plasma, but only a few have regarded their accurate quantification. This study reports on a new ultra-performance liquid chromatography tandem mass spectrometry method
Farid Dahmoune et al.
Food chemistry, 166, 585-595 (2014-07-24)
Phytochemicals, such as phenolic compounds, are of great interest due to their health-benefitting antioxidant properties and possible protection against inflammation, cardiovascular diseases and certain types of cancer. Maximum retention of these phytochemicals during extraction requires optimised process parameter conditions. A
Vivian Caetano Bochi et al.
Food chemistry, 176, 234-243 (2015-01-28)
Ceylon gooseberry is a deep-purple exotic berry that is being produced in Brazil with great market potential. This work aimed to determine major phenolic compounds in this specie by HPLC-PDA-ESI/MS. Samples were collected in two different seasons. Pulp and skin
D Stagos et al.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 65(6), 843-852 (2015-01-03)
The aim of the present study was to investigate the antiangiogenic potential of a grape stem extract against tube formation by human endothelial cells (EA.hy926). The results showed that at low and non-cytotoxic concentrations (50 and 100 μg/ml) the grape
Effects of feruloyl esterase, non-starch polysaccharide degrading enzymes, phytase, and their combinations on in vitro degradation of rice bran and nutrient digestibility of rice bran based diets in adult cockerels
Liu.Q, et al.
Livestock Science, 178, 255-262 (2015)
Inés Reverón et al.
Molecular nutrition & food research, 56(12), 1848-1859 (2012-10-16)
To advance knowledge of the stress tolerance mechanisms of a probiotic Lactobacillus plantarum strain to dietary hydroxycinnamic acids and the role of gut commensal microorganisms in the bioactivation of polyphenols. To understand how gut commensal microorganisms tolerate toxicity of hydroxycinnamic
Sun-Young Kang et al.
Microbial cell factories, 11, 153-153 (2012-12-05)
The phenylpropanoid metabolites are an extremely diverse group of natural products biosynthesized by plants, fungi, and bacteria. Although these compounds are widely used in human health care and nutrition services, their availability is limited by regional variations, and isolation of
Judith Müller et al.
Nature communications, 5, 5712-5712 (2014-12-17)
Increased expression of the Microphthalmia-associated transcription factor (MITF) contributes to melanoma progression and resistance to BRAF pathway inhibition. Here we show that the lack of MITF is associated with more severe resistance to a range of inhibitors, while its presence
Anna Vallverdú-Queralt et al.
Journal of agricultural and food chemistry, 60(38), 9667-9672 (2012-09-11)
The effect of pulsed electric fields on the polyphenol profile of tomato juices was studied. First, tomatoes were subjected to moderate-intensity pulsed electric fields (MIPEFs) and then were immediately refrigerated at 4 °C for 24 h. Treated and untreated juices
Robert Ramer et al.
Biochemical pharmacology, 91(2), 202-216 (2014-07-01)
Cannabinoids inhibit tumor neovascularization as part of their tumorregressive action. However, the underlying mechanism is still under debate. In the present study the impact of cannabinoids on potential tumor-to-endothelial cell communication conferring anti-angiogenesis was studied. Cellular behavior of human umbilical
Sema Demirci Çekiç et al.
Analytica chimica acta, 865, 60-70 (2015-03-04)
A colourimetric sensor capable of simultaneously measuring oxidative status (OS) in terms of the hazard produced by reactive oxygen species (ROS) and antioxidant activity (AOA) in regard to ROS-scavenging ability of antioxidant compounds was developed. The coloured cationic semi-quinone derivatives
Tomohiko Matsuta et al.
In vivo (Athens, Greece), 27(1), 77-83 (2012-12-15)
Previous studies have shown antiviral, antibacterial and anti-inflammatory activity of alkaline extract of the leaves of Sasa senanensis Rehder (SE). However, active components have not been identified. We isolated the substances that exhibit anti-UV activity and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity
Michele D'Ambrosio
Food chemistry, 138(4), 2079-2088 (2013-03-19)
γ-Oryzanol is an important phytochemical used in pharmaceutical, alimentary and cosmetic preparations. The present article, for the first time, discloses the performances of NP-HPLC in separating γ-oryzanol components and develops a validated method for its routine quantification. The analysis is
Caty Casas et al.
Scientific reports, 5, 9185-9185 (2015-03-19)
Neurodegenerative processes are preceded by neuronal dysfunction and synaptic disconnection. Disconnection between spinal motoneuron (MN) soma and synaptic target leads either to a retrograde degenerative process or to a regenerative reaction, depending injury proximity among other factors. Distinguished key events
Toshiki Furuya et al.
Applied and environmental microbiology, 78(17), 6087-6094 (2012-06-26)
Caffeic acid is a biologically active molecule that has various beneficial properties, including antioxidant, anticancer, and anti-inflammatory activities. In this study, we explored the catalytic potential of a bacterial cytochrome P450, CYP199A2, for the biotechnological production of caffeic acid. When
So-Yeon Shin et al.
Enzyme and microbial technology, 51(4), 211-216 (2012-08-14)
Resveratrol, a polyphenol compound found in grape skins, has been proposed to account for the beneficial effects of red wine against heart disease. To produce resveratrol in Saccharomyces cerevisiae, four heterologous genes were introduced: the phenylalanine ammonia lyase gene from
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