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显示 1-30 共 132 条结果 关于 "57-37-4" 范围 论文
Daniela Baldoni et al.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 17(6), 829-837 (2015-04-11)
Vitamin B12 (cyanocobalamin, Cbl) is accumulated by rapidly replicating prokaryotic and eukaryotic cells. We investigated the potential of a Tc-99m labelled Cbl derivative ([(99m)Tc]PAMA(4)-Cbl) for targeting infections caused by Escherichia coli and Staphylococcus aureus. In vitro binding assays were followed
D Manthey et al.
The Journal of biological chemistry, 274(21), 14716-14723 (1999-05-18)
A new mouse connexin gene has been isolated that codes for a connexin protein of 505 amino acid residues. Based on the predicted molecular mass of 57.115 kDa, it has been designated connexin-57. Similar to most other mouse connexin genes
J Asai et al.
Biochemical and biophysical research communications, 169(2), 788-795 (1990-06-15)
Using a highly sensitive and specific radioimmunoassay (RIA) for rat islet amyloid polypeptide (IAPP), we clarified regional distribution and molecular forms of rat IAPP. IAPP[1-37] and IAPP[19-37] were identified in normal rat pancreas by sequence analyses IAPP[19-37], accounting for 57%
Kenan Iltumur et al.
American heart journal, 151(5), 1115-1122 (2006-04-29)
B-type natriuretic peptide (BNP) is a neurohormone secreted mainly in the cardiac ventricles in response to volume expansion and pressure overload. The aim of this study was to assess plasma N-terminal proBNP (NT-proBNP) changes in acute ischemic stroke (AIS). The
Antonella Afeltra et al.
Arthritis and rheumatism, 53(3), 452-459 (2005-06-04)
To investigate the thrombotic tendency in patients with systemic lupus erythematosus (SLE) by evaluating congenital or acquired abnormalities associated with an increased risk of venous and/or arterial thrombosis. A total of 57 patients with SLE were included in the study.
M Tariq Javed et al.
Tuberculosis (Edinburgh, Scotland), 87(5), 437-445 (2007-06-16)
Spoligotyping is a typing tool used worldwide for epidemiological studies on Mycobacterium tuberculosis complex organisms; however it has received little attention regarding improvement of its discriminatory power (DP). In this study, we have evaluated a spoligotyping membrane prepared with 25
R F Frye et al.
Journal of chromatography. B, Biomedical applications, 677(1), 178-182 (1996-02-23)
A sensitive and specific reversed-phase high-performance liquid chromatographic assay was developed for the determination of debrisoquine and 4-hydroxydebrisoquine in urine. The urine samples were directly injected following an ether clean-up step which eliminated interference. Separation of the analytes was achieved
Marcel Dautzenberg et al.
The Journal of physiology, 589(Pt 19), 4731-4744 (2011-08-10)
Nitric oxide (NO) blunts the myogenic response (MR) in renal blood flow (RBF) autoregulation. We sought to clarify the roles of NO synthase (NOS) isoforms, i.e. neuronal NOS (nNOS) from macula densa, endothelial NOS (eNOS) from the endothelium, and inducible
Joseph P Glass et al.
International journal of surgical pathology, 19(5), 588-596 (2011-06-03)
Our study attempts to characterize mesothelin and GPR30 / estrogen receptor (ER) staining in pancreatic pathology. Immunohistochemical staining for mesothelin, GPR30, and ER was performed on a variety of pancreatic lesions. 24 of 42 (57%) adenocarcinomas stained for mesothelin, while
T Fujiwara et al.
The American journal of pathology, 153(4), 1063-1078 (1998-10-20)
A subset of hereditary and sporadic colorectal carcinomas is defined by microsatellite instability (MSI), but the spectra of gene mutations have not been characterized extensively. Thirty-nine hereditary nonpolyposis colorectal cancer syndrome carcinomas (HNPCCa) and 57 sporadic right-sided colonic carcinomas (SRSCCa)
Jessica S Fortin et al.
Bioorganic & medicinal chemistry, 16(15), 7477-7488 (2008-06-27)
Recently, a subset of N-phenyl-N'-(2-chloroethyl)ureas (CEU) was found abrogating the nuclear translocation of thioredoxin-1 and arresting the cell cycle in G(0)/G(1) phase. Several derivatives were prepared to assess their effect on cell cycle progression and on the intracellular location of
I Fiorini et al.
Journal of medicinal chemistry, 37(10), 1427-1438 (1994-05-13)
A novel class of ligands specific for MBR receptors has been identified: 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives. The majority of newly synthesized esters 37-64 as well as some intermediate ketones showed micro- or nanomolar affinity for [3H]PK 11195 binding inhibition. A SAR study
B F El-Rayes et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 21(10), 1999-2004 (2010-03-25)
Bevacizumab has demonstrated antitumor activity in multiple diseases. This phase II study was undertaken to determine the effects of adding bevacizumab to a regimen of docetaxel and oxaliplatin in patients with advanced adenocarcinoma of the stomach or gastroesophageal junction. Previously
Fatemeh Vakili et al.
3 Biotech, 10(10), 447-447 (2020-10-17)
The present study was designed to propose a simple, cost-effective, and efficient method for the preparation of a biocompatible composite made from magnetic diatomaceous earth (mDE) coated by aminopropyltriethoxysilane (APTES) and its application for immobilization of porcine pancreatic lipase (PPL).
E Doehring et al.
The American journal of tropical medicine and hygiene, 52(6), 546-548 (1995-06-01)
The sera of 849 Tanzanian pregnant women were tested at delivery for Toxoplasma gondii antibodies with the Sabin-Feldman dye test (DT) and an immunosorbent agglutination assay. A total of 296 (35%) of these women had DT titers greater than 1:4.
Pirkko Kellokumpu-Lehtinen et al.
Anticancer research, 33(6), 2623-2627 (2013-06-12)
Weekly paclitaxel is widely used in the treatment of metastatic breast cancer (MBC). Our aim was to test its efficacy and tolerability as a second-line therapy for MBC in daily oncology practice. Paclitaxel (90 mg/m(2)) was given intravenously three times
Naïke Bigé et al.
Critical care medicine, 43(6), 1246-1254 (2015-03-21)
To describe epidemiology and outcome of critically ill homeless patients, as compared with those of nonhomeless patients. Homeless and nonhomeless admissions were matched on the basis of a 1:4 ratio, using a propensity score-based procedure involving age, sex, date, and
Sheng-Hui Wu et al.
Behavior genetics, 47(4), 425-433 (2017-04-18)
This study examined genetic and environmental influences on the lipid concentrations of 1028 male twins using the novel univariate non-normal structural equation modeling (nnSEM) ADCE and ACE models. In the best fitting nnSEM ADCE model that was also better than
Kai-Li Zhang et al.
Oncology reports, 12(6), 1335-1340 (2004-11-18)
CYP1A1 expression in various tissues of 43 gastric cancer cases was analyzed with frozen tissue array-based immunohistochemical staining (IHC), RT-PCR, Western blot analysis and EROD (7-ethoxyresourfin-O-deethylase) assay. CYP1A1 was detected immunohistochemically in 86% (37/43) of gastric cancers, in both 57%
Helen Chan et al.
Neurochemistry international, 43(2), 137-146 (2003-03-07)
Increased levels of extracellular glutamate are a consistent feature of hepatic encephalopathy (HE) associated with liver failure and other hyperammonemic pathologies. Reduction of glutamate uptake has been described in ammonia-exposed cultured astrocytes, synaptosomes, and in animal models of hyperammonemia. In
Peng Wang et al.
American journal of clinical pathology, 134(4), 604-612 (2010-09-22)
We immunohistochemically evaluated UTF1 in 104 primary and 68 metastatic testicular germ cell tumors and 339 non-germ cell tumors. The percentage of tumor cells stained was semiquantitatively scored (0, no tumor cell staining; 1+, ≤30% of cells; 2+, 31%-60% of
Hideyuki Sasaki et al.
Prostaglandins, leukotrienes, and essential fatty acids, 148, 1-8 (2019-09-08)
Long-chain polyunsaturated fatty acids (LCPUFAs) are important constituents of biomembranes. Observation of blood fatty acids indicated that LCPUFA biosynthesis is affected by aging and FADS polymorphisms. This study examined the effects of aging and FADS polymorphisms on LCPUFA biosynthetic capacity
Chunlin Qin et al.
The Journal of biological chemistry, 281(12), 8034-8040 (2006-01-20)
Dentin matrix protein 1 (DMP1) is an acidic noncollagenous protein shown by gene ablations to be critical for the proper mineralization of bone and dentin. In the extracellular matrix of these tissues DMP1 is present as fragments representing the NH2-terminal
H F Seow et al.
Gene, 124(2), 291-293 (1993-02-28)
We have cloned a cDNA containing the complete coding sequence of ovine(ov) interleukin 4 (IL4) by the polymerase chain reaction using primers based on the 5' and 3' untranslated regions of the human IL4 gene. RNA was isolated from phorbol
Ahmed A Al-Qahtani et al.
Journal of chemotherapy (Florence, Italy), 26(3), 139-145 (2013-10-05)
The objectives of this study were to determine the prevalences, genotypes, and clonal relationships of extended-spectrum beta-lactamase (ESBL)-producing strains in 98 Klebsiella pneumoniae isolates from Riyadh. The prevalence of ESBLs in these strains was 37·75%. All isolates that were confirmed
T D Engerson et al.
The Journal of clinical investigation, 79(6), 1564-1570 (1987-06-01)
In response to global ischemia, tissue xanthine dehydrogenase was converted to xanthine oxidase in all tissues with half-times of conversion at 37 degrees C of approximately 3.6, 6, 7, and 14 h for the liver, kidney, heart, and lung, respectively.
M R Olthof et al.
The Journal of nutrition, 130(5), 1200-1203 (2000-05-10)
The flavonoid quercetin is an antioxidant which occurs in foods mainly as glycosides. The sugar moiety in quercetin glycosides affects their bioavailability in humans. Quercetin-3-rutinoside is an important form of quercetin in foods, but its bioavailability in humans is only
Ivy Song et al.
Journal of clinical pharmacology, 55(5), 490-496 (2014-12-03)
All commercially available integrase inhibitors are 2-metal binders and may be affected by co-administration with metal cations. The purpose of this study was to evaluate the effect of calcium and iron supplements on dolutegravir pharmacokinetics and strategies (dose separation and
R Fernández Labriola et al.
Acta psiquiatrica y psicologica de America latina, 37(4), 291-298 (1991-12-01)
One hundred and one depressed inpatients were treated by the authors with a second-generation antidepressive original molecule: Toloxatone, a specific and reversible MAO A inhibitor. Upon admission, all 101 patients with depressive illness did not score higher than 20 on
S Jafari et al.
Journal of clinical pharmacy and therapeutics, 40(4), 441-446 (2015-05-27)
Depression is a debilitating complication of brucellosis and how best to treat this is a matter of debate. Inflammatory processes are involved in the pathogenesis of both brucellosis and depression. Therefore, we hypothesized that celecoxib could be beneficial for the
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