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显示 1-30 共 1061 条结果 关于 "57-57-8" 范围 论文
G J Atwell et al.
Journal of medicinal chemistry, 32(2), 396-401 (1989-02-01)
A series of phenyl-substituted derivatives of the "minimal" DNA-intercalating agent N-[2-(dimethylamino)-ethyl]-2-phenylquinoline-8-carboxamide (1) have been synthesized and evaluated for in vivo antitumor activity, in a continuing search for active compounds of this class with the lowest possible DNA association constants. Substitution
Xia Cao et al.
Biochemical and biophysical research communications, 297(2), 288-293 (2002-09-19)
We have reported reversible oxidoreductive regulation of DNA-binding activity of Pax-8: oxidation inhibits its binding and subsequent reduction restores the binding. Here, we show that Cys-45 and Cys-57 in the paired domain of rat Pax-8, which are conserved in all
K A Alexander et al.
The Journal of biological chemistry, 262(13), 6108-6113 (1987-05-05)
P-57 is a neural-specific calmodulin binding protein with novel calmodulin binding properties. P-57 exhibits higher affinity for calmodulin-Sepharose in the absence of free Ca2+ than in the presence of Ca2+ (Andreasen, T.J., Luetje, C.W., Heideman, W. & Storm, D.R. (1983)
Lei Wang et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 25(4), 1029-1036 (2018-10-12)
Tailoring the morphology of a specific crystalline material through distinct crystal growth mechanisms (classical and nonclassical) is challenging. Herein, we report the two unique morphologies of a medium-pore (10×8-ring) zeolite, ZSM-57, prepared by employing an identical organic structure-directing agent (OSDA)
D Manthey et al.
The Journal of biological chemistry, 274(21), 14716-14723 (1999-05-18)
A new mouse connexin gene has been isolated that codes for a connexin protein of 505 amino acid residues. Based on the predicted molecular mass of 57.115 kDa, it has been designated connexin-57. Similar to most other mouse connexin genes
U Ribič et al.
Journal of applied microbiology, 122(5), 1186-1196 (2017-02-24)
The purpose of this study was the genotypic and phenotypic characterization of 57 strains of Staphylococcus epidermidis isolated from cleanroom environments, based on their biofilm formation and antimicrobial resistance profiles. Biofilm formation was investigated using real-time PCR (icaA, aap, bhp
Jilong Yang et al.
Technology in cancer research & treatment, 9(2), 161-169 (2010-03-12)
The expression of apurinic/apyrimidinic exonuclease 1 (APEX1) in tumors has been linked with chemoresistance, radioresistance, and shorter patient survival times. We sought to gain insight into the role of APEX1 in human osteosarcoma by evaluation of gene copy number alterations
B Stix et al.
The American journal of pathology, 159(2), 561-570 (2001-08-04)
We recently demonstrated the presence of matrix metalloproteinases (MMPs)-1, -2, and -3 in AA amyloid deposits, which lead us to speculate that MMPs may participate in amyloidogenesis by either processing the precursor protein, or by degrading the amyloid deposits. Here
Ta-Chih Liu et al.
The Kaohsiung journal of medical sciences, 19(1), 1-5 (2003-04-16)
The bone marrow and/or peripheral blood from 126 patients with acute myeloid leukemia (AML), 57 with chronic myeloid leukemia (CML), 91 with acute lymphocytic leukemia (ALL), and 178 normal controls were analyzed using a polymerase chain reaction-restriction fragment length polymorphism
Tomasz Ferenc et al.
Polish journal of pathology : official journal of the Polish Society of Pathologists, 55(4), 143-148 (2005-03-11)
PI6INK4A (P16) protein expression was analyzed immunohistochemically in archival material derived from 12 cases of follicular thyroid carcinoma, 57 cases of follicular adenoma and 17 cases of nodular goiter. Among follicular carcinomas, 11 out of 12 examined cases (91.7%) were
Daniela Baldoni et al.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 17(6), 829-837 (2015-04-11)
Vitamin B12 (cyanocobalamin, Cbl) is accumulated by rapidly replicating prokaryotic and eukaryotic cells. We investigated the potential of a Tc-99m labelled Cbl derivative ([(99m)Tc]PAMA(4)-Cbl) for targeting infections caused by Escherichia coli and Staphylococcus aureus. In vitro binding assays were followed
Evan J Anderson et al.
Vaccines, 8(1) (2020-02-12)
Background: Vaccinia is known to induce antibody and cellular responses. Plasmablast, circulating follicular helper T (cTFH) cells, cytokine-expressing CD4 T cells, and memory B cells were compared between subcutaneous (SC) and needle-free jet injection (JI) recipients of non-replicating modified vaccinia
Antonella Afeltra et al.
Arthritis and rheumatism, 53(3), 452-459 (2005-06-04)
To investigate the thrombotic tendency in patients with systemic lupus erythematosus (SLE) by evaluating congenital or acquired abnormalities associated with an increased risk of venous and/or arterial thrombosis. A total of 57 patients with SLE were included in the study.
A Wang-Gillam et al.
The Journal of biological chemistry, 273(42), 27055-27057 (1998-10-09)
We previously reported the purification of a UDP-N-acetylhexosamine (UDP-HexNAc) pyrophosphorylase from pig liver that catalyzed the synthesis of both UDP-GlcNAc and UDP-GalNAc from UTP and the appropriate HexNAc-1-P (Szumilo, T., Zeng, Y., Pastuszak, I., Drake, R., Szumilo, H., and Elbein
Toshiyuki Miura et al.
Journal of virology, 83(1), 140-149 (2008-10-31)
Human immunodeficiency virus type 1 (HIV-1)-infected persons who maintain plasma viral loads of <50 copies RNA/ml without treatment have been termed elite controllers (EC). Factors contributing to durable control of HIV in EC are unknown, but an HLA-dependent mechanism is
L He et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 28(5), 337-339 (2002-03-01)
To investigate the clinicopathological, immunohistochemical features and the histogenesis of pancreatoblastoma (PB) in 14 pediatric cases, including 9 male and 5 female patients, their age ranged from 1.5 to 8 years with a mean of 4.4 years. Routine pathological, histochemical
Neda A Moatamed et al.
Journal of clinical pathology, 68(6), 484-487 (2015-02-25)
Cytokeratin 7 (CK 7) negative breast tumours are reported to occur rarely. We studied 14 CK 7 negative cases of primary invasive ductal carcinoma (IDC) detected during sentinel lymph node metastases work-up and immunohistochemistry panel in the work-up of metastatic
Jacqueline E Calvano et al.
Clinical immunology (Orlando, Fla.), 121(2), 186-190 (2006-07-11)
Mutations (Asp299Gly and Thr399Ile) in the human Toll-like receptor 4 (hTLR4) gene are reportedly associated with hyporesponsiveness to inhaled LPS in humans. It was hypothesized that normal volunteers with these hTLR4 mutations would manifest altered physiological responses to intravenous LPS
Xun Li et al.
Pathology oncology research : POR, 18(1), 57-60 (2011-06-15)
PI3K/AKT constitutes an important pathway regulating the signaling of multiple biological processes and plays a critical role in carcinogenesis. PIK3CA gene missense mutations have been reported in many human cancer types. The mutation of it in hepatocellular carcinoma cases varies
Koji Tsuta et al.
Pathology, research and practice, 208(8), 470-474 (2012-07-10)
The majority of neuroendocrine carcinomas (NECs) express somatostatin (SST) receptors (SSTRs). However, the expression of all 5 SSTR subtypes in pulmonary NECs has not been reported. We performed immunohistochemical analysis of all 5 SSTR subtypes (including the SSTR2A and 2B
Paulette Mhawech-Fauceglia et al.
American journal of clinical pathology, 133(6), 899-908 (2010-05-18)
Differentiating uterine serous carcinoma (USC) from endometrioid adenocarcinoma (EAC) could be problematic, especially in high-grade EACs and tumors exhibiting architectural variations. To address this issue, we evaluated 103 endometrial carcinoma cases using 4 immunomarkers, beta-catenin, IMP3, PTEN, and p53. Cases
T Ohtsubo et al.
Nucleic acids research, 28(6), 1355-1364 (2000-02-24)
An enzyme activity introducing an alkali-labile site at 2-hydroxyadenine (2-OH-A) in double-stranded oligonucleotides was detected in nuclear extracts of Jurkat cells. This activity co-eluted with activities toward adenine paired with guanine and 8-oxo-7,8-dihydroguanine (8-oxoG) as a single peak corresponding to
M Ollikainen et al.
Oncogene, 26(31), 4541-4549 (2007-01-30)
Mutations in the DNA mismatch repair gene MLH1 are a major cause of hereditary nonpolyposis colorectal cancer (HNPCC). No mutant phenotype is observed before the wild-type (wt) allele is somatically inactivated in target tissue. We addressed the mechanisms of MLH1
Guo-Hua Li et al.
Canadian journal of physiology and pharmacology, 83(3), 267-277 (2005-05-05)
This study aimed to investigate the effect of the activation of dopamine (DA) receptors on ATP-activated currents (IATP) in freshly isolated dorsal root ganglion (DRG) neurons of rats using whole-cell patch clamp technique in combination with intracellular dialysis. Extracellular application
Seong-Ho Yoo et al.
Journal of Korean medical science, 20(1), 50-55 (2005-02-18)
Pleomorphic carcinoma of the lung (PCL) is characterized by a mixture of sarcomatoid and carcinoma components, and a poor prognosis. However, no immunophenotype of tumor markers has been characterized in PCL. To characterize the immunophenotype for CD99 in PCL, we
Renly Lim et al.
International urogynecology journal, 29(7), 997-1004 (2017-07-27)
We evaluated patients' perception and satisfaction with nonsurgical pulsed magnetic stimulation (PMS) for treatment of female stress urinary incontinence (SUI) in a randomized, double-blind, sham-controlled trial. Women with SUI (n = 120) were randomized to either active or sham PMS for 8 weeks
F H Arthur
Journal of economic entomology, 94(3), 772-779 (2001-06-27)
Last instar larvae of the red flour beetle, Tribolium castaneum (Herbst), and the confused flour beetle, Tribolium confusum Jacquelin du Val, were either exposed for 8-144 h on concrete treated with 1.9 x 10(-3) mg(AI)/per cm2 hydroprene, or continually exposed
Grégory Schmit et al.
Pathobiology : journal of immunopathology, molecular and cellular biology, 88(1), 88-94 (2020-10-28)
The coronavirus disease 2019 (COVID-19) infection, caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), involves several organs through participation of angiotensin-conversion enzyme 2 (ACE2) receptors. The presence of ACE2 receptors in the liver renders this organ a potential
T H Hyndman et al.
Australian veterinary journal, 97(4), 93-102 (2019-03-29)
Inclusion body disease (IBD) is a disease of snakes with a global distribution and has recently been shown to be caused by reptarenaviruses. Testing for this group of viruses in asymptomatic snakes allows the association between infection and disease to
H Ueno et al.
International journal of cancer, 84(5), 470-477 (1999-09-30)
We examined production and tissue localization of 7 different matrix metalloproteinases (MMP-1, -2, -3, -7, -8, -9 and -13) and 2 tissue inhibitors of metalloproteinases (TIMP-1 and -2) in human endometrial-carcinoma tissues. Sandwich enzyme immunoassays showed enhanced production of MMP-7
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