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显示 1-21 共 21 条结果 关于 "57-83-0" 范围 论文
Qin Li et al.
Transfusion medicine (Oxford, England), 20(6), 369-375 (2010-07-31)
This work aims to explain the complexity of the Knops blood group system in the Chinese population. The Knops blood group system consists of antigens encoded by CR1 gene exon 29. A total of 281 individuals from the Han, Uigur
Paul J Wrigley et al.
Molecular pain, 6, 71-71 (2010-10-28)
There is anatomical and behavioural evidence that μ- and δ-opioid receptors modulate distinct nociceptive modalities within the superficial dorsal horn. The aim of the present study was to examine whether μ- and δ-opioid receptor activation differentially modulates TRP sensitive inputs
Martin Widschwendter et al.
The Lancet. Oncology, 14(12), 1226-1232 (2013-10-22)
Penetrance for breast cancer, ovarian cancer, or both in carriers of BRCA1/BRCA2 mutations is disproportionately high. Sex hormone dysregulation and altered end-organ hormone sensitivity might explain this organ-specific penetrance. We sought to identify differences in hormone regulation between carriers of
P Opfermann et al.
Clinical and experimental immunology, 180(1), 131-142 (2014-11-18)
Reparixin, a CXCR 1/2 antagonist, has been shown to mitigate ischaemia-reperfusion injury (IRI) in various organ systems in animals, but data in humans are scarce. The aim of this double-blinded, placebo-controlled pilot study was to evaluate the safety and efficacy
Martin Reck et al.
The Lancet. Respiratory medicine, 7(5), 387-401 (2019-03-30)
The IMpower150 trial showed significant improvements in progression-free and overall survival with atezolizumab plus bevacizumab plus carboplatin plus paclitaxel (ABCP) versus the standard-of-care bevacizumab plus carboplatin plus paclitaxel (BCP) in chemotherapy-naive patients with non-squamous non-small-cell lung cancer. Here, we report
Akira Tsuburaya et al.
The Lancet. Oncology, 15(8), 886-893 (2014-06-24)
The prognosis for locally advanced gastric cancer is poor despite advances in adjuvant chemotherapy. We did the Stomach cancer Adjuvant Multi-Institutional group Trial (SAMIT) to assess the superiority of sequential treatment (paclitaxel then tegafur and uracil [UFT] or paclitaxel then
Alice T Shaw et al.
The Lancet. Oncology, 12(11), 1004-1012 (2011-09-22)
ALK gene rearrangement defines a new molecular subtype of non-small-cell lung cancer (NSCLC). In a recent phase 1 clinical trial, the ALK tyrosine-kinase inhibitor (TKI) crizotinib showed marked antitumour activity in patients with advanced, ALK-positive NSCLC. To assess whether crizotinib
Gregory A Masters et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 1(7), 673-678 (2007-04-06)
Carboplatin and gemcitabine are one standard regimen for patients with advanced non-small cell lung cancer (NSCLC). The oral proapoptotic agent exisulind is a cyclic guanosine monophosphate phosphodiesterase that increases apoptosis in vitro. We performed a phase II trial of carboplatin
Peter C Rockers et al.
The Lancet. Global health, 7(4), e492-e502 (2019-02-26)
Novartis Access is a Novartis programme that offers a portfolio of non-communicable disease medicines at a wholesale price of US$1 per treatment per month in low-income and middle-income countries. We evaluated the effect of Novartis Access in Kenya, the first
Jay A van Gerpen et al.
Neurology, 93(14), e1339-e1347 (2019-09-06)
To evaluate the pattern and severity of autonomic dysfunction in autopsy-confirmed progressive supranuclear palsy (PSP) compared to α-synuclein pathology. Autopsy-confirmed cases of 14 patients with PSP, 18 with multiple system atrophy (MSA), and 24 with Lewy body disease (LBD) with
Sarah M McCurdy et al.
American journal of physiology. Heart and circulatory physiology, 301(2), H497-H505 (2011-05-24)
Secreted protein, acidic, and rich in cysteine (SPARC) is a matricellular protein that functions in the extracellular processing of newly synthesized collagen. Collagen deposition to form a scar is a key event following a myocardial infarction (MI). Because the roles
Emilie Lalonde et al.
The Lancet. Oncology, 15(13), 1521-1532 (2014-12-03)
Clinical prognostic groupings for localised prostate cancers are imprecise, with 30-50% of patients recurring after image-guided radiotherapy or radical prostatectomy. We aimed to test combined genomic and microenvironmental indices in prostate cancer to improve risk stratification and complement clinical prognostic
A F Hahn et al.
Brain : a journal of neurology, 113 ( Pt 5), 1511-1525 (1990-10-01)
Modern techniques have defined the hereditary motor and sensory neuropathies (HMSN) as a genetically heterogeneous group of disorders. This includes a rare variant with X-linked dominant inheritance. We have traced this disorder through 6 generations of a large Canadian kindred;
Gülşah Akdemir et al.
Annals of the rheumatic diseases, 77(1), 111-118 (2017-10-04)
To determine the 5-year outcomes of early remission induction therapy followed by targeted treatment aimed at drug-free remission (DFR) in patients with early arthritis. In 12 hospitals, 610 patients with early (<2 years) rheumatoid arthritis (RA) or undifferentiated arthritis (UA)
Dengfeng Cao et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(2), 288-296 (2010-11-09)
LIN28 has been shown to have an important role in primordial germ cell development and malignant transformation of germ cells in mouse. In this study, we examined the immunohistochemical profile of LIN28 in 131 primary human extragonadal germ cell tumors
Dengfeng Cao et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(2), 288-296 (2010-11-09)
LIN28 has been shown to have an important role in primordial germ cell development and malignant transformation of germ cells in mouse. In this study, we examined the immunohistochemical profile of LIN28 in 131 primary human extragonadal germ cell tumors
Ke Wu et al.
The British journal of nutrition, 123(8), 841-848 (2020-01-23)
Human milk fat is specially tailored to supply the developing infant with adequate and balanced nutrients. The present study aimed to quantify the composition of fatty acids, tocopherols and carotenoids in human milk, with special emphasis on the lactational changes.
Michel P Hermans et al.
European journal of clinical investigation, 42(7), 729-737 (2012-01-10)
Imbalance in nitric oxide (NO), an atheroprotective vasodilator, is associated with endothelial dysfunction, cardiovascular diseases (CVD) and diabetic complications. Various endothelial NO synthase (eNOS) polymorphisms may affect NO bioavailability, thereby promoting adverse cardiovascular milieu. To analyze glucose homeostasis, cardiometabolic phenotype
Anne Brücken et al.
Critical care (London, England), 19, 408-408 (2015-11-19)
Inhaled nitric oxide (iNO) improves outcomes when given post systemic ischemia/reperfusion injury. iNO given during cardiopulmonary resuscitation (CPR) may therefore improve return of spontaneous circulation (ROSC) rates and functional outcome after cardiac arrest (CA). Thirty male Sprague-Dawley rats were subjected
Kiran Jakate et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 26(1), 95-105 (2012-08-25)
The current World Health Organization classification divides endometrial sarcomas into low-grade endometrial stromal sarcoma and undifferentiated endometrial sarcoma. Recent studies suggest undifferentiated endometrial sarcoma is a heterogeneous group and a subgroup with uniform nuclei is more akin to low-grade endometrial
A Santana et al.
Journal of dairy science, 106(9), 6060-6079 (2023-07-21)
The aim of this study was to evaluate the inclusion of alfalfa grazing during 8 h continuous or partitioned in 2 separated sessions of 4 h after each milking, on nutrient intake, digestibility, ruminal fermentation, feeding behavior, milk production, milk
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