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显示 1-30 共 52 条结果 关于 "600-36-2" 范围 论文
Dan Zhang et al.
Xenobiotica; the fate of foreign compounds in biological systems, 45(3), 239-243 (2014-09-19)
1.The aim of the study was to evaluate the pharmacokinetics of peramivir after single intravenous (i.v.) doses in healthy Chinese subjects. 2.In a cross-over study, 12 subjects were given 300 and 600 mg peramivir by i.v. infusion. Blood and urine samples
Namgoo Kang et al.
Chemosphere, 63(10), 1685-1698 (2005-12-06)
The Fenton's system is applied to the destruction of perchloroethylene (PCE) present as a dense non-aqueous phase liquid (DNAPL) in soil slurry systems; the initial concentration of PCE was 45 times higher than its aqueous solubility. Studies were conducted in
Maria Eduarda L Diogenes et al.
The Journal of nutrition, 145(7), 1515-1523 (2015-05-29)
Pregnancy and lactation in adolescents with low calcium intake may impair fetal growth and infant bone mass. We investigated the effects of calcium plus vitamin D supplementation during pregnancy in Brazilian adolescent mothers consuming low calcium diets (∼600 mg/d) on
D M Roseman et al.
Bioconjugate chemistry, 7(2), 187-195 (1996-03-01)
Polyclonal antibody-based enzyme-linked immunosorbent assays (ELISAs) were developed for the detection of retrorsine (1, 351 g/mol), monocrotaline (2, 325 g/mol), and retronecine (3, 155 g/mol) in the parts per billion (ppb) range. A set of three bifunctional linking arms (6-8)
Hui-Kai Huang et al.
Journal of industrial microbiology & biotechnology, 39(1), 55-62 (2011-06-18)
A heat-labile phenolic acid decarboxylase from Candida guilliermondii (an anamorph of Pichia guilliermondii) was purified to homogeneity by simple successive column chromatography within 3 days. The molecular mass was 20 kDa by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and 36 kDa
Kumar Babita et al.
Current drug delivery, 1(4), 397-403 (2005-11-25)
Skin perturbation with ethanol followed by application of beta-chloroalanine (beta-CA) or atorvastatin (AVN) was employed for delaying the recovery of sphingosine (a precursor of ceramide) and cholesterol, respectively in epidermis of rats. Dose optimization studies revealed 600 microg of beta-CA
Raman K Marwaha et al.
The British journal of nutrition, 121(5), 538-548 (2019-03-08)
In India, there is a lack of information about the adequate daily dose of vitamin D3 supplementation in school children. Hence, we undertook this study to evaluate the adequacy and efficacy of different doses of vitamin D3 in schoolchildren. A
Kim S Sugamori et al.
Cancer letters, 318(2), 206-213 (2011-12-24)
The aromatic amine 4-aminobiphenyl (ABP) is a liver procarcinogen in mice, requiring enzymatic bioactivation to exert its tumorigenic effect. To assess the role of arylamine N-acetyltransferase (NAT)-dependent acetylation capacity in the risk for ABP-induced liver tumors, we compared 1-year liver
Rachel Dosnon-Olette et al.
Chemosphere, 79(2), 117-123 (2010-02-27)
Remediation capacities of two freshwater microalgae, Scenedesmus obliquus and Scenedesmus quadricauda, were assessed for the removal of two fungicides (dimethomorph and pyrimethanil) and one herbicide (isoproturon) from their medium. To ensure these studies were performed with healthy algae, pesticide effects
Manos Stefanakis et al.
Spine, 37(22), 1883-1891 (2012-06-19)
Mechanical and biochemical analyses of cadaveric and surgically removed discs. To test the hypothesis that fissures in the annulus of degenerated human discs are mechanically and chemically conducive to the ingrowth of nerves and blood vessels. Discogenic back pain is
Jonas Söderholm et al.
PloS one, 8(2), e56991-e56991 (2013-02-26)
Interferon and ribavirin therapy for chronic hepatitis C virus (HCV) infection yields sustained virological response (SVR) rates of 50-80%. Several factors such as non-1 genotype, beneficial IL28B genetic variants, low baseline IP-10, and the functionality of HCV-specific T cells predict
Craig Reynolds et al.
Investigational new drugs, 30(3), 1232-1240 (2011-09-17)
Uncontrolled studies comparing pentostatin (P), cyclophosphamide (C), and rituximab (R) (PCR) to fludarabine plus C+R (FCR) suggest similar efficacy with fewer infectious complications with PCR. We compared FCR and PCR in previously-untreated or minimally-treated B-cell chronic lymphocytic leukemia (CLL). FCR
Gregori Casals et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 960, 8-13 (2014-05-02)
Gas chromatography-mass spectrometry (GC-MS) remains as the gold-standard technique for the study of the steroid metabolome. A main limitation is the need of performing a derivatization step since incubation with strong silylations agents for long periods of time (usually 16
Tal Anahory et al.
Electrophoresis, 23(7-8), 1197-1202 (2002-05-01)
Proteins present in human follicular fluid (HFF) have been poorly characterized to date. The purpose of our study was to analyse the protein content and identify new proteins originating from fluid of mature human follicles. A total of six females
E Ben-Hur et al.
Photochemistry and photobiology, 65(3), 456-460 (1997-03-01)
The silicon phthalocyanine HOSiPcOSi(CH3)2(CH2)3 N(CH3)2 (Pc 4), is being studied as a photosensitizer for virus inactivation in red blood cell concentrates (RBCC). The RBCC spiked with cell-free human immunodeficiency virus (HIV) or with HIV actively replicating in the T-lymphocytic cell
Babita S Gupta et al.
International journal of pharmaceutics, 238(1-2), 43-50 (2002-05-09)
The present study was designed to investigate the role of skin sphingosine synthesis inhibition in enhancing the in vitro permeation of levodopa (LD), a hydrophilic drug, across rat skin. beta-Chloroalanine (beta-CA), a selective inhibitor of serine palmitoyl transferase was used
Angelica Nogueira-Rodrigues et al.
Cancer, 120(8), 1187-1193 (2014-03-13)
Cisplatin-based chemoradiation (CRT) is the standard treatment for patients with locally advanced cervical cancer. Epidermal growth factor receptor (EGFR) is frequently overexpressed in cervical cancer, and EGFR inhibition itself has antitumor effects and potentiates CRT. Results of a previous phase
Photodegradation of decabromodiphenyl ether adsorbed onto clay minerals, metal oxides, and sediment.
Mi-Youn Ahn et al.
Environmental science & technology, 40(1), 215-220 (2006-01-26)
The photodebromination of decabromodiphenyl ether (BDE-209) adsorbed onto six different solid matrixes was investigated in sunlight and by irradiation with 350 +/- 50 nm lamps (four lamps at 24 W each). After 14 days of lamp irradiation, BDE-209 degraded with
Shiyuan Ding et al.
Journal of hazardous materials, 262, 812-818 (2013-10-22)
Photocatalytic degradation of sulfamethoxazole (SMX) was investigated using Bi2O3/Bi2O2CO3/Sr6Bi2O9 (BSO) photocatalyst under visible light (>420 nm) irradiation. The photochemical degradation of SMX followed pseudo-first-order kinetics. The reaction kinetics was determined as a function of initial SMX concentrations (5-20 mg L(-1))
Kiran Dhakal et al.
Chemical research in toxicology, 25(12), 2796-2804 (2012-11-10)
Polychlorinated biphenyls (PCBs) are legacy pollutants that exert toxicities through various mechanisms. In recent years exposure to PCBs via inhalation has been recognized as a hazard. Those PCBs with lower numbers of chlorine atoms (LC-PCBs) are semivolatile and have been
Mitko D Mitkov et al.
Folia medica, 55(1), 55-63 (2013-08-03)
Erectile dysfunction (ED) is the inability to develop and/or maintain an erection that is sufficient for satisfactory sexual intercourse. The prevalence of erectile dysfunction in diabetic men is 28-75%, this percentage rising with patient's age and duration of diabetes. The
Annemieke C Heijboer et al.
Clinical endocrinology, 83(1), 105-110 (2015-01-06)
A possible association between serum 25-hydroxyvitamin D and testosterone levels has been reported; however, contradictory results have emerged. To investigate a causal link between vitamin D and testosterone status, we studied the effect of vitamin D supplementation on serum testosterone
M Margalit et al.
Human reproduction (Oxford, England), 27(5), 1238-1248 (2012-03-10)
The prostate and testis expression (PATE)-like family of proteins are expressed mainly in the male genital tract. They are localized in the sperm head and are homologous to SP-10, the acrosomal vesicle protein also named ACRV1. Our aim was to
Lucia Valentínová et al.
PloS one, 7(4), e34541-e34541 (2012-04-12)
Heterozygous glucokinase (GCK) mutations cause a subtype of maturity-onset diabetes of the young (GCK-MODY). Over 600 GCK mutations have been reported of which ∼65% are missense. In many cases co-segregation has not been established and despite the importance of functional
C L O'Neal et al.
Forensic science international, 95(1), 1-10 (1998-08-27)
Acetylcodeine (AC), an impurity of illicit heroin synthesis, was investigated as a urinary biomarker for detection of illicit heroin use. One hundred criminal justice urine specimens that had been confirmed positive by GC/MS for morphine at concentrations > 5000 ng/ml
Wenjiang Zhang et al.
Drug metabolism and disposition: the biological fate of chemicals, 31(6), 768-772 (2003-05-21)
Buprenorphine is a thebaine derivative used in the treatment of heroin and other opiate addictions. In this study, the selective probe reactions for each of the major hepatic cytochromes P450 (P450s) were used to evaluate the effect of buprenorphine and
B Wode-Helgodt et al.
Psychopharmacology, 73(1), 55-62 (1981-01-01)
Efforts to find a correlation between serum levels of chlorpromazine (CPZ) and clinical effect have been rather unsuccessful, which could be due to fluctuations of CPZ and CPZ metabolite levels during treatment, the complicated metabolism of CPZ, or to varying
A Ljungqvist et al.
Proceedings of the National Academy of Sciences of the United States of America, 85(21), 8236-8240 (1988-11-01)
Antide is the decapeptide N-Ac-D-Nal(2),D-Phe(pCl),D-Pal(3),Ser,Lys(Nic),D-Lys(Nic),Leu,Lys(iPr),P ro,D- Ala-NH2 [Nal(2) represents 3-(2-naphthyl)alanine; Phe(p-Cl) represents 3-(4-chlorophenyl)alanine; Pal(3) represents 3-(3-pyridyl)alanine; Lys(Nic) represents N epsilon-nicotinoyllysine; Lys-(iPr) represents N epsilon-isopropyllysine], which is an antagonist of luteinizing hormone-releasing hormone (LHRH), which has high antiovulatory activity, releases negligible
Jeremie Guedj et al.
Hepatology (Baltimore, Md.), 59(5), 1706-1714 (2014-01-01)
Alisporivir (ALV) is a cyclophilin inhibitor with pan-genotypic activity against hepatitis C virus (HCV). Here, we characterize the viral kinetics observed in 249 patients infected with HCV genotypes 2 or 3 and treated for 6 weeks with different doses of
Chao Chen et al.
Clinical therapeutics, 37(2), 349-357 (2014-12-04)
Coadministration of morphine with oral gabapentin has been shown to increase plasma gabapentin concentrations. This study evaluated whether there was any interaction between gabapentin enacarbil (GEn), which is a prodrug of gabapentin, and morphine in terms of pharmacokinetics, pharmacodynamics, safety
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