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Emma Puighermanal et al.
Hippocampus, 25(7), 858-875 (2014-12-30)
Increasing evidences suggest that dopamine facilitates the encoding of novel memories by the hippocampus. However, the role of dopamine D2 receptors (D2R) in such regulations remains elusive due to the lack of the precise identification of hippocampal D2R-expressing cells. To
Chris J Malajczuk et al.
Biochimica et biophysica acta, 1828(9), 2041-2055 (2013-05-28)
Molecular dynamics (MD) simulations have been used to investigate the interactions of a variety of hydroxylated cryosolvents (glycerol, propylene glycol and ethylene glycol), methanol and dimethyl sulfoxide (DMSO) in aqueous solution with a 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) bilayer in its fluid phase
Zhixun Xie et al.
PloS one, 9(4), e94685-e94685 (2014-04-16)
We report a novel electrochemical immunosensor that can sensitively detect avian influenza virus H5 subtype (AIV H5) captured by graphene oxide-H5-polychonal antibodies-bovine serum albumin (GO-PAb-BSA) nanocomposite. The graphene oxide (GO) carried H5-polychonal antibody (PAb) were used as signal amplification materials.
Hong-Bo Pang et al.
Nature communications, 5, 4904-4904 (2014-10-04)
Neuropilins (NRPs) are trans-membrane receptors involved in axon guidance and vascular development. Many growth factors and other signalling molecules bind to NRPs through a carboxy (C)-terminal, basic sequence motif (C-end Rule or CendR motif). Peptides with this motif (CendR peptides)
Ethylene glycol poisoning: current diagnostic and management issues.
Larissa I Velez et al.
Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association, 33(4), 342-345 (2007-07-24)
Beatriz M Souza et al.
Caries research, 49(5), 499-507 (2015-08-19)
This study evaluated the effect of an experimental paste containing hydroxyapatite in nanoparticles (nano-HA)/fluoride on dental de-remineralisation in situ. Thirteen subjects took part in this crossover/randomised/double-blind study performed in 4 phases (14 days each). Four sound and 4 pre-demineralised specimens
Chenyan Hu et al.
ChemSusChem, 8(23), 4005-4015 (2015-11-14)
Photocatalytic fuel cells (PFCs) are constructed from anodized photoanodes with the aim of effectively converting organic materials into solar electricity. The syntheses of the photoanodes (TiO2 , WO3 , and Nb2 O5 ) were optimized using the statistical 2(k) factorial
Xin Li et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 969, 181-189 (2014-09-03)
A robust two-dimensional liquid chromatography (2D-LC) method for determining the free and total concentrations of vancomycin in plasma was developed and validated. The 2D-LC system, which exhibited a strong capacity for inhibiting interference, comprised a unique RP1-IEX-RP2 column system and
L Schoderboeck et al.
Gene therapy, 22(5), 357-364 (2015-01-30)
Lentiviral vectors have proved an effective method to deliver transgenes into the brain; however, they are often hampered by a lack of spread from the site of injection. Modifying the viral envelope with a portion of a rabies envelope glycoprotein
Rossana Canavesi et al.
Journal of pharmaceutical and biomedical analysis, 97, 141-150 (2014-05-28)
Pantethine (d-bis-(N-pantothenyl-β-aminoethyl)-disulfide, PAN), the stable disulfide form of pantetheine, has beneficial effects in vascular diseases being able to decrease the hyperlipidaemia, moderate the platelet function and prevent the lipid peroxidation. Furthermore, recent studies suggested that PAN may be an effective
Qinghua Liu et al.
Nature communications, 5, 5122-5122 (2014-10-07)
There remains a pressing challenge in the efficient utilization of visible light in the photoelectrochemical applications of water splitting. Here, we design and fabricate pseudobrookite Fe2TiO5 ultrathin layers grown on vertically aligned TiO2 nanotube arrays that can enhance the conduction
Nagore Ortiz-Vitoriano et al.
The journal of physical chemistry letters, 6(13), 2636-2643 (2015-08-13)
Understanding the oxygen reduction reaction kinetics in the presence of Na ions and the formation mechanism of discharge product(s) is key to enhancing Na-O2 battery performance. Here we show NaO2 as the only discharge product from Na-O2 cells with carbon
Xue Wang et al.
Nature communications, 6, 7594-7594 (2015-07-03)
Conformal deposition of platinum as ultrathin shells on facet-controlled palladium nanocrystals offers a great opportunity to enhance the catalytic performance while reducing its loading. Here we report such a system based on palladium icosahedra. Owing to lateral confinement imposed by
Hua Wang et al.
Acta crystallographica. Section F, Structural biology communications, 70(Pt 10), 1402-1405 (2014-10-08)
β-Carboline alkaloids (βCs), with tricyclic pyrido[3,4-b]indole rings, have important pharmacological and therapeutic value. In the biosynthesis of βCs, the Pictet-Spengler (PS) cyclization reaction is responsible for the formation of ring structures. McbB is one of a few enzymes that are
Robert D Scalley et al.
American family physician, 66(5), 807-812 (2002-09-27)
Ingestion of ethylene glycol may be an important contributor in patients with metabolic acidosis of unknown cause and subsequent renal failure. Expeditious diagnosis and treatment will limit metabolic toxicity and decrease morbidity and mortality. Ethylene glycol poisoning should be suspected
Lauren C Harte-Hargrove et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(4), 1723-1738 (2015-01-30)
The mossy fiber (MF) pathway is critical to hippocampal function and influenced by gonadal hormones. Physiological data are limited, so we asked whether basal transmission and long-term potentiation (LTP) differed in slices of adult male and female rats. The results
Jing Peng et al.
Materials science & engineering. C, Materials for biological applications, 56, 438-443 (2015-08-08)
Titania nanotube (TNT) delivery of fetal bovine serum (FBS) was conducted on titanium (Ti) to enhance bone tissue repair. Scanning electron microscopy (SEM) and energy dispersive spectrometer (EDS) showed FBS increased the tube wall thickness and decreased the tube diameter.
Yang Yu et al.
Journal of neural transmission (Vienna, Austria : 1996), 122(4), 593-606 (2014-08-13)
Sporadic Alzheimer's disease (AD) is a multifactorial metabolic brain disorder characterized by progressive neurodegeneration. Decreased brain energy and glucose metabolism occurs before the appearance of AD symptoms and worsens while the disease progresses. Deregulated brain insulin signaling has also been
Mohamed R Berber et al.
Scientific reports, 5, 16711-16711 (2015-11-26)
Driven by the demand for the commercialization of fuel cell (FC) technology, we describe the design and fabrication of a highly durable FC electrocatalyst based on double-polymer-coated carbon nanotubes for use in polymer electrolyte membrane fuel cells. The fabricated electrocatalyst
Qiang Shi et al.
Colloids and surfaces. B, Biointerfaces, 125, 28-33 (2014-12-02)
There is an urgent need to develop blood-contacting biomaterials with long-term anti-hemolytic capability. To obtain such biomaterials, we coaxially electrospin [ascorbic acid (AA) and lecithin]/poly (ethylene oxide) (PEO) core-shell nanofibers onto the surface of styrene-b-(ethylene-co-butylene)-b-styrene elastomer (SEBS) that has been
Luis Miguel Azofra et al.
Physical chemistry chemical physics : PCCP, 15(33), 14026-14036 (2013-07-19)
The mechanism of the S(N)2 model glycosylation reaction between ethanol, 1,2-ethanediol and methoxymethanol has been studied theoretically at the B3LYP/6-311+G(d,p) computational level. Three different types of reactions have been explored: (i) the exchange of hydroxyl groups between these model systems;
Wen Jen Lin et al.
Carbohydrate polymers, 120, 7-14 (2015-02-11)
The aim of this study was to develop hepatocyte-targeting non-viral polymeric nono-carriers for gene delivery. Chitosan was selected as the main polymer. An asialoglycoprotein receptor recognized sugar, galactose, was introduced. The methoxy poly(ethylene glycol) (mPEG) or short chain poly(ethylene glycol)
Filipa Pires et al.
Biochimica et biophysica acta, 1850(6), 1158-1168 (2015-02-11)
The use of conjugated polymers allows versatile interactions between cells and flexible processable materials, while providing a platform for electrical stimulation, which is particularly relevant when targeting differentiation of neural stem cells and further application for therapy or drug screening.
Qian Qin et al.
Journal of separation science, 38(16), 2857-2864 (2015-05-29)
The levels of catecholamines, especially dopamine, epinephrine and norepinephrine in urine and plasma have been used to assist the diagnosis and treatment of psychosis. Due to their low endogenous concentrations, the determination of the three major catecholamines is very difficult.
Alfonso Pérez-Garrido et al.
Bioorganic & medicinal chemistry, 17(2), 896-904 (2008-12-06)
This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoretical molecular descriptors, calculated solely from the molecular structure of the compounds under investigation
Tomohiro Isobe et al.
Animal science journal = Nihon chikusan Gakkaiho, 86(7), 661-665 (2014-12-10)
The optimization of single-embryo culture conditions is very important, particularly in the in vitro production of bovine embryos using the ovum pick-up (OPU) procedure. The purpose of this study was to examine the development of embryos derived from oocytes obtained
Rungusa Pantan et al.
Life sciences, 116(1), 31-36 (2014-08-26)
The aim of this study is to investigate the vasorelaxant effect of 16-O-acetyldihydroisosteviol (ADIS) and its underlying mechanisms in isolated rat aorta. Rat aortic rings were isolated, suspended in organ baths containing Kreb's solution, maintained at 37°C, and mounted on
Yang Zhang et al.
Journal of the American Chemical Society, 137(14), 4709-4719 (2015-03-21)
Self-assembling nanoparticles of amphiphilic polymers can transport hydrophobic molecules across hydrophilic media and, as a result, can be valuable delivery vehicles for a diversity of biomedical applications. Strategies to monitor their dynamics noninvasively and in real time are, therefore, essential
Xuan Zhong Li et al.
Journal of microbiology and biotechnology, 23(2), 195-204 (2013-02-16)
While structured packing modules are known to be efficient for surface wetting and gas-liquid exchange in abiotic surface catalysis, this model study explores structured packing as a growth surface for catalytic biofilms. Microbial biofilms have been proposed as self-immobilized and
Nae Tanpradit et al.
Theriogenology, 83(9), 1553-1561 (2015-03-10)
The objectives of the study were to (1) examine and optimize the impact of sucrose during slow freezing and (2) compare the results of two freezing methods (slow freezing and vitrification) on cellular viability (germinal and stromal cells), follicle morphology
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