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显示 1-30 共 176 条结果 关于 "64-17-5" 范围 论文
Jai Woong Seo et al.
Journal of controlled release : official journal of the Controlled Release Society, 151(1), 28-34 (2011-01-19)
Changes in lipid acyl chain length can result in desorption of lipid from the liposomal anchorage and interaction with blood components. PET studies of the stability of such lipids have not been performed previously although such studies can map the
Rohit Bhargava et al.
American journal of clinical pathology, 123(6), 889-895 (2005-05-19)
We studied HER-2/neu (HER-2) and topoisomerase IIa (topo2a) amplification (using chromogenic in situ hybridization) and overexpression (immunohistochemical analysis) in 113 invasive breast carcinomas. A gene copy number/chromosome 17 copy number ratio of 2.0 or higher indicated amplification. A topo2a/chromosome 17
Selma B Souto et al.
Arquivos brasileiros de endocrinologia e metabologia, 56(9), 672-676 (2013-01-19)
Virilising ovarian tumours are a rare cause of hyperandrogenism in women, accounting for less than 5% of all ovarian neoplasms. It occurs most often in - and postmenopausal women. We report a case of a 64 year-old woman with signs
Nai-Kong V Cheung et al.
JAMA, 307(10), 1062-1071 (2012-03-15)
Neuroblastoma is diagnosed over a wide age range from birth through young adulthood, and older age at diagnosis is associated with a decline in survivability. To identify genetic mutations that are associated with age at diagnosis in patients with metastatic
H Jørgensen et al.
Journal of neuroendocrinology, 14(10), 788-795 (2002-10-10)
The neurotransmitter serotonin (5-HT) stimulates adrenocorticotropic hormone (ACTH) secretion from the anterior pituitary gland via activation of central 5-HT1 and 5-HT2 receptors. The effect of 5-HT is predominantly indirect and may be mediated via release of hypothalamic corticotropin-releasing hormone (CRH).
Qiang Huang et al.
BMC cancer, 21(1), 1074-1074 (2021-10-03)
The human miR-17-92 polycistron is the first reported and most well-studied onco-miRNA with a cluster of seven miRNAs. miR-17-5p, a member of the miR-17-92 family, plays an important role in tumor cell proliferation, apoptosis, migration and invasion. However, few studies
Zhuo Chen et al.
Bioorganic & medicinal chemistry, 16(3), 1337-1344 (2007-11-13)
Saxifraga stolonifera, an evergreen dicotyledon, has been identified as an important resource in Chinese medicine due to its anticancer activity. In the present report, chemical components of S. stolonifera (L) Meeb which is found in Guizhou province were investigated. Ten
Jianhua Liu et al.
Journal of medicinal chemistry, 53(19), 6973-6985 (2010-09-09)
In order to advance therapeutic applications of nicotinic ligands, continuing research efforts are being directed toward the identification and characterization of novel nicotinic acetylcholine receptor (nAChR) ligands that are both potent and subtype selective. Herein we report the synthesis and
A Z Balboula et al.
Reproduction (Cambridge, England), 146(4), 407-417 (2013-07-31)
Cathepsin B was found to be correlated inversely with the quality of bovine oocytes and embryos. The aims of this study were to evaluate i) the relationship between heat shock during in vitro maturation (IVM) of bovine cumulus-oocyte complexes (COCs)
Y J Zhou et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 32(12), 902-907 (2001-10-13)
Twenty-one 1-[2-[[(substituted-phenyl) methyl] thio]-2-(2, 4-difluorophenyl) ethyl]-1H-1,2,4-triazoles were synthesized and 19 compounds are reported for the first time. Results of biological tests in vitro showed that the antifungal activities of all title compounds were better than or comparable to the activities
Pirus Ghadjar et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24(12), 1910-1916 (2006-04-20)
The liver is the primary organ of metastasis in colorectal cancer (CRC). Chemokine receptor CCR6 is expressed on a subset of T cells and is associated with their migration into the liver. This study was performed to analyze a possible
Yu Gao et al.
Environmental pollution (Barking, Essex : 1987), 187, 81-89 (2014-01-28)
We investigated the association between indoor air pollutants and childhood acute leukemia (AL). A total of 105 newly diagnosed cases and 105 1:1 gender-, age-, and hospital-matched controls were included. Measurements of indoor pollutants (including nitrogen dioxide (NO2) and 17
Sven Dänicke et al.
Archives of animal nutrition, 67(1), 15-36 (2013-01-11)
Ergot alkaloids (the sum of individual alkaloids is termed as total alkaloids, TA) are mycotoxins of the fungus Claviceps purpurea and might adversely affect the performance and aspects of liver physiology of pigs. The objective of the study was to
K Yasuda et al.
Biochemical and biophysical research communications, 256(1), 75-80 (1999-03-06)
The 105-kDa heat shock protein (HSP105) is a member of the high-molecular-mass heat shock protein family. We have isolated and characterized the mouse HSP105 gene including about 1.2 kb of the 5'-flanking region. The mouse HSP105 gene spans about 22
Hadi Reihani et al.
Iranian journal of immunology : IJI, 12(2), 82-93 (2015-06-30)
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. Emerging data suggests that T helper 17 (Th17) cells play a pathogenic role in SLE and the increased number of these cells correlates with disease activity. In recent years, 1α, 25-dihydroxyvitamin
Cristina Woellner et al.
The Journal of allergy and clinical immunology, 125(2), 424-432 (2010-02-18)
The hyper-IgE syndrome (HIES) is a primary immunodeficiency characterized by infections of the lung and skin, elevated serum IgE, and involvement of the soft and bony tissues. Recently, HIES has been associated with heterozygous dominant-negative mutations in the signal transducer
Kristen A Neville et al.
Clinical endocrinology, 82(5), 657-662 (2015-01-20)
It is unclear whether the rate of vitamin D deficiency in paediatric cancer survivors is higher than in the background population, and whether this is of pathological significance. 25OHD was measured in a previously studied group of 208 survivors (n
Eric Smith et al.
Molecular cancer, 4, 42-42 (2005-12-15)
Metallothionein 3 (MT3) inhibits growth in a variety of cell types. We measured MT3 gene expression by RT-PCR, and DNA methylation in the MT3 promoter by combined bisulphite restriction analysis, in four oesophageal cancer cell lines and the resected oesophagus
The role of matrix metalloproteinases and cysteine-cathepsins on the progression of dentine erosion.
B L Zarella et al.
Archives of oral biology, 60(9), 1340-1345 (2015-07-03)
To evaluate in vitro the effect of the inhibition of endogenous dentinal enzymes (matrix metalloproteinases-MMPs and cysteine cathepsins-CCs) on dentine erosion. Dentine blocks (4mm×4mm×2mm) from sound human teeth were randomly divided into 7 groups (n=17) according to the treatment: MMP-
Adam Horn et al.
Archives of pathology & laboratory medicine, 137(4), 546-551 (2013-04-03)
Diagnoses rendered as atypical/suspicious for malignancy on fine-needle aspiration (FNA) of pancreatic mass lesions range from 2% to 29% in various studies. We have identified the expression of 3 genes, MUC4, MUC16, and NGAL that are highly upregulated in pancreatic
Barbara Goeggel Simonetti et al.
Clinical neuroradiology, 29(1), 143-151 (2017-11-04)
Knowledge about the localization and outcome of iatrogenic dissection (ID) during endovascular treatment of acute ischemic stroke (AIS) is limited. We aimed to determine the frequency, clinical aspects and morphology of ID in endovascular AIS treatment and to identify predictors
Mei Gao et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 40(3-4), 727-742 (2016-12-05)
Vulvovaginal candidiasis (VVC) is a common gynecological disease. Candida albicans is believed to be mainly implicated in VVC occurrence, the biofilm of which is one of the virulence factors responsible for resistance to traditional antifungal agents especially to fluconazole (FCZ).
Shingo Matsumoto et al.
International journal of cancer, 118(10), 2498-2504 (2005-12-15)
Mutations of the epidermal growth factor receptor gene (EGFR) have been reported to be present in a considerable fraction of lung adenocarcinomas showing dramatic response to EGFR tyrosine kinase inhibitors. To clarify pathogenic significance of the mutations for the development
Bunyong Phakdeekitcharoen et al.
Clinical endocrinology, 74(2), 152-159 (2010-11-04)
In Conn's syndrome, hypokalaemia normally results from renal potassium loss because of the effect of excess aldosterone on Na(+) -K(+) -ATPase in principal cells. Little is known about the effect of aldosterone on cellular potassium redistribution in skeletal muscle. Our
Bjarke Feenstra et al.
Nature genetics, 44(3), 334-337 (2012-02-07)
Infantile hypertrophic pyloric stenosis (IHPS) is a severe condition characterized by hypertrophy of the pyloric sphincter muscle. We conducted a genome-wide association study (GWAS) on 1,001 surgery-confirmed cases and 2,401 controls from Denmark. The six most strongly associated loci were
Laura Grandoso et al.
European journal of pharmacology, 517(1-2), 51-58 (2005-06-25)
The aim of the present study was to investigate the modulation of locus coeruleus neurons by the selective serotonin (5-HT) reuptake inhibitor citalopram using single-unit extracellular recordings in rat brain slices. Citalopram inhibited the activity of a subpopulation of locus
M J Zuidema et al.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 14(6), 484-489 (2014-10-08)
Acute pancreatitis has a highly variable clinical course. Early and reliable predictors for the severity of acute pancreatitis are lacking. Proteinuria appears to be a useful predictor of disease severity and outcome in a variety of clinical conditions. This study
M M Porter-Turner et al.
British journal of biomedical science, 68(4), 203-207 (2012-01-24)
This paper investigates the effect of glycation on glucose transport in erythrocytes. Glucose transporter function, numbers and erythrocyte phosphorylation rates are simultaneously studied using 30 Caucasian patients with diabetes and 30 Caucasian control volunteers (mean +/- SD where P <
Andrea Gómez-Maqueo et al.
Molecules (Basel, Switzerland), 26(17) (2021-09-11)
High hydrostatic pressure (HHP) is a commercial processing technology which can enhance the health potential of foods by improving the bioaccessibility of their bioactive compounds. Our aim was to study the bioaccessibility and digestive stability of phenolic compounds and betalains
L Baker et al.
British journal of cancer, 102(4), 719-726 (2010-01-28)
The deprivation gap for breast cancer survival remains unexplained by stage at presentation, treatment, or co-morbidities. We hypothesised that p53 mutation might contribute to the impaired outcome observed in patients from deprived communities. p53 mutation status was determined using the
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