搜索范围
650536
应用筛选条件
关键词:'650536'
显示 1-30 #N/A 99 条结果 关于 "650536" 范围 论文
Courtney A Ober et al.
AAPS PharmSciTech, 13(4), 1396-1406 (2012-10-12)
Cocrystals of itraconazole, an antifungal drug with poor bioavailability, and succinic acid, a water-soluble dicarboxylic acid, were formed by gas antisolvent (GAS) cocrystallization using pressurized CO(2) to improve itraconazole dissolution. In this study, itraconazole and succinic acid were simultaneously dissolved
Francisco Rodríguez-Ropero et al.
Journal of computational chemistry, 32(9), 1876-1886 (2011-04-05)
The effect on the structural and thermodynamic properties in water/n-heptane interfaces on addition of NaCl, MgCl(2), and ZnCl(2) has been examined through five independent 100-ns molecular dynamics simulations. Results indicate that the interfacial thickness within the framework of the capillary-wave
Wenjuan Lu et al.
Journal of hazardous materials, 186(2-3), 2166-2170 (2011-01-18)
The extraction of Au(III) from hydrochloric acid solutions by microemulsion was studied. The extraction experiments were carried out using cetyltrimethylammonium bromide (CTAB) as surfactant and iso-amyl alcohol as co-surfactant. Au(III) was found to be extracted into the microemulsion phase due
Samira Hezaveh et al.
The Journal of chemical physics, 136(12), 124901-124901 (2012-04-03)
In this paper, the conformation and dynamics properties of polyethylene oxide (PEO) and polypropylene oxide (PPO) polymer chains at 298 K have been studied in the melt and at infinite dilution condition in water, methanol, chloroform, carbon tetrachloride, and n-heptane
Bing Chen et al.
Journal of hazardous materials, 188(1-3), 369-374 (2011-02-26)
The influence of the initial fuel temperature on the burning behavior of n-heptane pool fire was experimentally studied at the State Key Laboratory of Fire Science (SKLFS) large test hall. Circular pool fires with diameters of 100mm, 141 mm, and
Alexandre Grand-Guillaume Perrenoud et al.
Journal of chromatography. A, 1360, 275-287 (2014-08-19)
Superficially porous particles (SPP), or core shell particles, which consist of a non-porous silica core surrounded by a thin shell of porous silica, have gained popularity as a solid support for chromatography over the last decade. In the present study
Giorgia Purcaro et al.
Analytical and bioanalytical chemistry, 407(1), 309-319 (2014-09-12)
The potentiality of a multidimensional comprehensive gas chromatographic (GC × GC) method, employing a simultaneous dual detection (FID and mass spectrometer), to generate peculiar two-dimensional chromatograms to be used as a chemical fingerprint, was investigated to characterize minor compounds in edible oil
Michael H Abraham et al.
European journal of medicinal chemistry, 43(3), 478-485 (2007-06-05)
Values of in vitro gas to lung partition coefficients, K(lung), of VOCs have been collected from the literature. For 44 VOCs, application of the Abraham solvation equation to log K(lung) yielded a correlation with R(2)=0.968 and S.D.=0.25 log units. Combination
Robert T Dauchy et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 54(1), 40-50 (2015-02-05)
Early studies on rodents showed that short-term exposure to high-intensity light (> 70 lx) above 600 nm (red-appearing) influences circadian neuroendocrine and metabolic physiology. Here we addressed the hypothesis that long-term, low-intensity red light exposure at night (rLEN) from a
M Geldof et al.
British journal of pharmacology, 154(6), 1369-1378 (2008-05-22)
The pharmacokinetic-pharmacodynamic (PK-PD) correlation of fluvoxamine 5-HT transporter (SERT) occupancy was determined in rat frontal cortex ex vivo. Rats (n=47) with permanent arterial and venous cannulas received a 30 min intravenous infusion of fluvoxamine (1 or 7.3 mg kg(-1)). At
Jiawang Ding et al.
Analytical chemistry, 86(19), 9412-9416 (2014-09-16)
Exposure to pathogens in recreational or drinking water is a serious public health concern. It is important to rapidly determine and identify trace levels of pathogens in real environmental samples. We report here on a label-free potentiometric aptasensor for rapid
Saet Buyl Lee et al.
Plant & cell physiology, 56(1), 48-60 (2014-10-13)
The aerial parts of all land plants are covered with hydrophobic cuticular wax layers that act as the first barrier against the environment. The MYB94 transcription factor gene is expressed in abundance in aerial organs and shows a higher expression
M M Szutowski et al.
Folia medica Cracoviensia, 31(3), 175-184 (1990-01-01)
Methanol interacts with cytochrome P-450 to produce the reversed type I spectral change. In the presence of type I substrate n-heptane, the methanol induced spectrum disappears without detectable effects of interaction suggesting that methanol is a very weak ligand for
Raquel Garcia et al.
Journal of separation science, 38(7), 1204-1212 (2015-02-07)
Aiming to implement an analytical methodology that is highly selective for the extraction and quantification of terbuthylazine from olive oil, we successfully achieved: (i) the development of a molecularly imprinted polymer by bulk polymerization using terbuthylazine as template molecule, methacrylic
Mathias Schaffrath et al.
Journal of chromatography. A, 1363, 270-277 (2014-07-22)
Chiral spirocyclic terpenoids are abundant natural flavors with significant impact particularly on the food industry. Chromatographic methods for analytical and preparative separation of these compounds are therefore of high interest to natural product chemists in academia and industry. Gas chromatography
Arun K Kota et al.
Advanced materials (Deerfield Beach, Fla.), 24(43), 5838-5843 (2012-08-30)
Hierarchically structured, superoleophobic surfaces are demonstrated that display one of the lowest contact angle hysteresis values ever reported - even with extremely low-surface-tension liquids such as n-heptane. Consequently, these surfaces allow, for the first time, even ≈2 μL n-heptane droplets
Vikram Karde et al.
International journal of pharmaceutics, 475(1-2), 351-363 (2014-09-10)
Influence of surface modification on wettability and surface energy characteristics of three micron size pharmaceutical excipient powders was studied using hydrophilic and hydrophobic grades of nano-silica. The wetting behavior assessed from contact angle measurements using sessile drop and liquid penetration
Jun Luo et al.
Science China. Life sciences, 58(4), 379-389 (2014-12-22)
Collective migration of loosely or closely associated cell groups is prevalent in animal development, physiological events, and cancer metastasis. However, our understanding of the mechanisms of collective cell migration is incomplete. Drosophila border cells provide a powerful in vivo genetic
Benjamin Kehimkar et al.
Talanta, 103, 267-275 (2012-12-04)
An algorithm, referred to as targeted mass spectral ratio analysis (TMSRA) is presented whereby the ratios between intensities as a function of mass channel (m/z) of a target analyte mass spectrum are used to automatically determine which m/z are sufficiently
Qiu-yu Xu et al.
Acta pharmacologica Sinica, 35(10), 1265-1273 (2014-09-16)
To investigate the metabolite changes caused by simvastatin or fenofibrate intervention in diet-induced hyperlipidemia rats using a GC-MS-based metabolomic profiling approach. SD rats were fed with high-lipid diet for 4 weeks to induce hyperlipidemia, then the rats were fed with
Si Chen et al.
Molecular bioSystems, 10(12), 3310-3321 (2014-10-16)
As a classical formula, Sini decoction (SND) has been fully proved to be clinically effective in treating doxorubicin (DOX)-induced cardiomyopathy. Current chemomics and pharmacology proved that the total alkaloids (TA), total gingerols (TG), total flavones and total saponins (TFS) are
Thiloka C Ariyasena et al.
Journal of chromatography. A, 1361, 240-254 (2014-08-30)
Retention factors on several columns and at various temperatures using gas chromatography and from reversed-phase liquid chromatography on a SunFire C18 column with various mobile phase compositions containing acetonitrile, methanol and tetrahydrofuran as strength adjusting solvents are combined with liquid-liquid
Gábor Csordás et al.
PloS one, 9(6), e98191-e98191 (2014-06-04)
In recent years, Drosophila melanogaster has become an attractive model organism in which to study the structure and development of the cellular immune components. The emergence of immunological markers greatly accelerated the identification of the immune cells (hemocytes), while the
Toni E Newsome et al.
Journal of chromatography. A, 1364, 261-270 (2014-09-15)
Nanofibrous silica-based stationary phases for electrospun ultra-thin layer chromatography (E-UTLC) are described. Nanofibers were produced by electrospinning a solution of silica nanoparticles dispersed in polyvinylpyrrolidone solutions to create composite silica/polymer nanofibers. Stationary phases were created from as-spun nanofibers, or the
Amine Kassouf et al.
Analytica chimica acta, 839, 14-25 (2014-07-30)
Olive oil is one of the most valued sources of fats in the Mediterranean diet. Its storage was generally done using glass or metallic packaging materials. Nowadays, plastic packaging has gained worldwide spread for the storage of olive oil. However
Wei Xiuhua et al.
Talanta, 94, 289-294 (2012-05-23)
A microemulsion enhanced electrochemiluminescence (ECL) of luminol-H(2)O(2) was studied with the flow-injection (FI) technique. The results revealed that the microemulsion composed with cetyltrimethylammonium bromide (CTAB), n-butanol, n-heptane and water greatly enhanced the ECL especially in acidic medium. The ECL emission
Emilie Destandau et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 985, 29-37 (2015-02-04)
An innovative procedure coupling pressurized solvent extraction and centrifugal partition chromatography (CPC) used in linear gradient elution mode was developed to isolate two pure germacranolides (9α-hydroxyparthenolide and 9β-hydroxyparthenolide) and to separate flavonoids (nepetin, isorhamnetin and jaceosidin) and chlorophyll pigments from
Céline Rivière et al.
Fitoterapia, 97, 253-260 (2014-06-10)
Neuroinflammatory processes are involved in the pathogenesis of many neurodegenerative disorders. Microglial cells, the main immune cells of the central nervous system, represent a target of interest to search for naturally occurring anti-inflammatory products. In this study, we evaluated the
Vikrant Rachakonda et al.
Alcoholism, clinical and experimental research, 38(11), 2712-2721 (2014-11-26)
Dysregulated adipose tissue metabolism has been implicated in the pathogenesis of alcoholic liver disease in murine models. We aimed to characterize serum markers of adipose tissue metabolism and inflammation in patients with severe acute alcoholic hepatitis (AAH) and determine their
Dany Spaggiari et al.
Journal of chromatography. A, 1371, 244-256 (2014-12-03)
The goal of this study was to evaluate the combination of powerful chromatographic methods and compact single quadrupole MS device for simple in vitro cytochrome P450 (CYP) inhibition assay, instead of more expensive triple quadrupole MS/MS detectors. For this purpose
1/4