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关键词:'68-12-2'
显示 31-60 共 415 条结果 关于 "68-12-2" 范围 论文
Anthony Franklin et al.
BJU international, 127(1), 71-79 (2020-06-12)
To evaluate the ability of preoperative multiparametric magnetic resonance imaging (mpMRI) and a gallium-68 prostate-specific membrane antigen positron emission tomography/computed tomography (68 Ga-PSMA PET/CT) scan to predict pathological outcomes and also identify a group of men with a <5% risk
Mehri Fayazi et al.
In vitro cellular & developmental biology. Animal, 51(4), 408-414 (2014-12-18)
The aim of this study was to investigate the potential differentiation of CD146(+) endometrial stem cells to several lineages. Endometrial stromal cells were cultured using Dulbecco's modified Eagle's medium/Hams F-12 (DMEM/F-12) and were passaged every 7-10 d when cultures reached
Hemal Mehta et al.
The British journal of ophthalmology, 102(4), 479-482 (2017-08-06)
To determine whether early vision gains predict long-term visual outcomes in the BEVORDEX randomised clinical trial of bevacizumab or dexamethasone implants for diabetic macular oedema. Post hoc analysis of 68 study eyes (77%) that completed 2 years follow-up of the
Jessica D Panes et al.
Frontiers in pharmacology, 11, 709-709 (2020-06-12)
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive impairment that increasingly afflicts the elderly population. Soluble oligomers (AβOs) has been implicated in AD pathogenesis: however, the molecular events underlying a role for Aβ are not well understood. We
Mohammad Taghi Ghorbanian et al.
Neurological research, 32(2), 185-193 (2009-05-09)
Bone marrow stromal cells (BMSCs) were documented as a feasible candidate for cell therapy. Several protocols with one or more steps, using different chemicals, were used for inducing BMSCs differentiation into neuronal phenotype. Many of these chemicals were reported to
Marian Danilewicz et al.
Folia histochemica et cytobiologica, 48(1), 63-67 (2010-06-10)
Both idiopathic IgA nephropathy (IgAN) and Schoenlein-Henoch nephritis (SHN) are characterized by cell proliferation and abnormal extracellular matrix (ECM) remodeling by mesangial cells leading to fibrosis, sclerosis and end-stage renal disease. Matrix metalloproteinases MMP-2 and MMP-9 are reported as the
D H Presky et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(24), 14002-14007 (1996-11-26)
We have identified a cDNA from a human phytohemagglutinin-activated lymphoblast library encoding a protein that binds 125I-labeled human interleukin 12 (125I-huIL-12) with a Kd of about 5 nM when expressed in COS-7 cells. When coexpressed in COS-7 cells with the
Clara Quintas et al.
Neurochemistry international, 55(7), 505-513 (2009-05-19)
In the sympathetic nervous system, ATP is a co-transmitter and modulator of transmitter release, inhibiting noradrenaline release by acting on P2Y autoreceptors, but in peripheral tissues the subtypes involved have only scarcely been identified. We investigated the identity of the
Arash Rafii Tabrizi et al.
Journal of the American College of Surgeons, 194(3), 267-273 (2002-03-15)
Warfarin sodium (warfarin) is commonly prescribed in surgical practice. Warfarin use is complicated by an unpredictable dose response that may be due in part to genetically determined differences in metabolic capacity. To better understand the interaction between genotype and response
Melissa Oliveira-Cunha et al.
Pancreas, 41(3), 428-434 (2012-03-17)
Pancreatic and periampullary cancers have a high incidence of activating KRAS mutations. The aim of this study was to determine the incidence of KRAS and EGFR mutations in pancreatic and periampullary cancers and their relationship with survival. One hundred patients
Smadar Avigad et al.
Pediatric blood & cancer, 53(6), 1023-1028 (2009-07-29)
Ewing sarcoma (ES) is the second most common solid bone and soft tissue malignancy in children and young adults with low cure rates indicating the need to identify further prognostic markers. The importance of methylation in the inactivation of key
Arzu Pinar Erdem et al.
Pediatric dentistry, 33(2), 165-170 (2011-06-28)
The purpose of this study was to evaluate the total success rates of mineral trioxide aggregate (MTA), ferric sulfate (FS), and formocresol (FC) as pulpotomy agents in primary molars. A randomized, split-mouth study design was used in 32 healthy 5-
Rajesh H Tale et al.
Bioorganic & medicinal chemistry letters, 21(15), 4648-4651 (2011-07-09)
A series of novel 3,4-dihydropyrimidin-2(1H)-one urea derivatives of biological interest were prepared by sequential Bigineli's reaction, reduction followed by reaction of resulting amines with different arylisocynates. All the synthesized (1-23) compounds were screened against the pro-inflammatory cytokines (TNF-α and IL-6)
David L Wyles et al.
Hepatology (Baltimore, Md.), 60(1), 56-64 (2014-02-07)
This phase II trial assessed the efficacy and safety of a combination regimen of the nonstructural protein (NS)5A inhibitor ledipasvir (LDV), NS3 protease inhibitor vedroprevir (VDV), non-nucleoside NS5B inhibitor tegobuvir (TGV), and ribavirin (RBV) in treatment-naïve patients with chronic hepatitis
Zhengren Xu et al.
Organic & biomolecular chemistry, 9(7), 2512-2517 (2011-02-23)
The total synthesis of protein kinase C activator (-)-indolactam V (IL-V) has been successfully completed with two separate approaches: From known 4-nitrotryptophan derivative 3 in 8 steps (49% overall yield) and from L-glutamic acid in 12 steps (18% overall yield)
Hiroaki Bessho et al.
Molecular vision, 17, 977-982 (2011-05-05)
To determine the association of age-related maculopathy susceptibility 2 (ARMS2) gene polymorphisms with the phenotype of typical neovascular age-related macular degeneration (tAMD) and polypoidal choroidal vasculopathy (PCV) and the effects of photodynamic therapy (PDT). The single nucleotide polymorphisms at rs10490924
Sarrah Ayuandari et al.
Journal of assisted reproduction and genetics, 33(12), 1585-1593 (2016-07-29)
To study the influence of xenotransplantation on follicular recruitment and growth in cryopreserved/thawed human ovarian tissue. Two 3-mm pieces of cryopreserved/thawed human ovarian tissue obtained from female cancer patients (n = 11) were xenotransplanted into a subcutaneous neck pouch of 6-week-old ovarectomized
Stéphane Richard et al.
PLoS genetics, 1(6), e74-e74 (2005-12-20)
The Src substrate associated in mitosis of 68 kDa (Sam68) is a KH-type RNA binding protein that has been shown to regulate several aspects of RNA metabolism; however, its physiologic role has remained elusive. Herein we report the generation of
Heimo H Wenzl et al.
Digestive diseases and sciences, 60(5), 1414-1423 (2014-11-09)
Many patients with quiescent Crohn's disease are maintained on long-term treatment with azathioprine (AZA), but controlled data are limited. We aimed to evaluate the efficacy of AZA therapy for more than 4 years to maintain clinical remission. We performed a
K Tabynov et al.
Vaccine, 32(25), 2965-2971 (2014-04-15)
We previously created a live vaccine against equine influenza based the new reassortant cold-adapted (Ca) strain A/HK/Otar/6:2/2010. The live vaccine contains surface proteins (HA, NA) from the wild-type virus A/equine/Otar/764/2007 (Н3N8; American Lineage Florida Clade 2), and internal proteins (PB2
K D Tremblay et al.
Molecular and cellular biology, 17(8), 4322-4329 (1997-08-01)
The imprinted mouse H19 gene is hypermethylated on the inactive paternal allele in somatic tissues and sperm. Previous observations from a limited analysis have suggested that methylation of a few CpG dinucleotides in the region upstream from the start of
T Bergan et al.
Chemotherapy, 32(6), 478-485 (1986-01-01)
The study was aimed at analyzing the pharmacokinetics of sulphadiazine (SDZ) and trimethoprim (TMP) in geriatric patients and was carried out in two stages. The first stage compared 11 geriatric patients (68-89 years old) and 9 healthy volunteers (21-34 years
Jin You Kim et al.
AJR. American journal of roentgenology, 202(4), 912-921 (2014-03-26)
The purpose of this study was to retrospectively investigate whether 3D breast density changes measured using MRI were associated with recurrent cancer in patients with breast cancer who received adjuvant tamoxifen. A search of the breast MRI database (2007-2008) revealed
Qian Xu et al.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 31(1), 107-109 (2009-09-22)
The spinocerebellar ataxias (SCAs) are a clinically and genetically heterogeneous group of neurodegenerative diseases. Researchers have recently found that SCA type 11 (SCA11) is associated with mutations in the TTBK2 gene. In our previous work, we performed mutation detection in
Konstantinos Spanos et al.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 28(1), 14-19 (2020-09-02)
To analyze aortic arch anatomy of patients who were already treated with a 2-inner-branch arch endograft (2-IBAE) in order to assess the anatomical suitability of the supra-aortic arteries as target vessels for a 3-IBAE. Three different configurations of the Cook
Carol A Feghali-Bostwick et al.
American journal of respiratory and critical care medicine, 177(2), 156-163 (2007-11-03)
Adaptive immune responses are present in patients with chronic obstructive pulmonary disease (COPD), and it has been postulated that these processes could be autoreactive. To ascertain if humoral autoimmunity could play a role in COPD pathogenesis. Circulating IgG autoantibodies were
P V Suneetha et al.
Journal of medical virology, 78(8), 1055-1060 (2006-06-22)
Host immunity plays an important role in viral persistence and progression of liver disease in HCV infected patients. IL-12 induces production of IFN-gamma, a potent antiviral agent. IL-12 comprises two subunits; IL-p35 and IL-12p40, which are encoded by two different
Sheila Weitzman et al.
Pediatric blood & cancer, 53(7), 1271-1276 (2009-09-05)
A prospective phase II Histiocyte Society study, LCH-S-98, evaluated the efficacy of 2-chlorodeoxyadenosine (2-CdA) monotherapy as salvage therapy in Langerhans cell histiocytosis (LCH). Patients with poor and intermediate risk LCH not responsive to initial therapy and patients with low-risk chronic
Sönke Detlefsen et al.
Medicine, 97(31), e11641-e11641 (2018-08-05)
The diagnosis of autoimmune pancreatitis (AIP) and its differential diagnosis from pancreatic cancer (PC) can be challenging. In this retrospective study, we aimed to evaluate the value of anti-plasminogen binding peptide (a-PBP), immunoglobulin G4 (IgG4), and anti-carbonic anhydrase-II (a-CA-II), together
Jae B Park
Journal of medicinal food, 14(3), 226-231 (2011-02-22)
Typheramide (N-caffeoyltyramine) and alfrutamide (N-feruloyltyramine) are phenylpropenoic acid amides found in plants. In this article, typheramide and alfrutamide were isolated from Allium sativum (garlic) and Allium fistulosum (green onion), their chemical structures were confirmed using nuclear magnetic resonance spectroscopic methods
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