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Joana M Silva et al.
Soft matter, 12(4), 1200-1209 (2015-12-01)
The design of self-standing multilayered structures based on biopolymers has been attracting increasing interest due to their potential in the biomedical field. However, their use has been limited due to their gel-like properties. Herein, we report the combination of covalent
Mikhail Y Maslov et al.
Journal of controlled release : official journal of the Controlled Release Society, 194, 257-265 (2014-09-23)
Prior studies in small mammals have shown that local epicardial application of inotropic compounds drives myocardial contractility without systemic side effects. Myocardial capillary blood flow, however, may be more significant in larger species than in small animals. We hypothesized that
Julie Vanacker et al.
Fertility and sterility, 99(5), 1363-1368 (2013-02-05)
To evaluate the survival and growth potential of human preantral follicles isolated before and after cryopreservation. Pilot study. Gynecology research unit in a university hospital. Six women aged 27 to 32 years. Six ovarian biopsy samples were cut into two
Saisubramanian Nagarajan et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(15), E1538-E1547 (2014-04-08)
Studies of replicative and chronological lifespan in Saccharomyces cerevisiae have advanced understanding of longevity in all eukaryotes. Chronological lifespan in this species is defined as the age-dependent viability of nondividing cells. To date this parameter has only been estimated under
Christina Monsen et al.
Journal of vascular surgery, 59(1), 145-151 (2013-09-24)
Vacuum-assisted wound closure (VAC) therapy may heal wounds faster than conventional dressings after surgical debridement of perivascular groin infections after vascular surgery. Patients with deep infected wounds (Szilagyi grade III) were surgically revised and left open for secondary healing, then
James P K Armstrong et al.
Advanced healthcare materials, 5(14), 1724-1730 (2016-04-30)
3D tissue printing with adult stem cells is reported. A novel cell-containing multicomponent bioink is used in a two-step 3D printing process to engineer bone and cartilage architectures.
Mohammad Ali Khosravi Zanjani et al.
Iranian journal of pharmaceutical research : IJPR, 17(2), 753-766 (2018-06-09)
Microencapsulation with hydrocolloids as a modern technique has been used to prolong the survival of probiotics during exposure to harsh conditions. In this study, alginate-Hylon starch microcapsules with genipin cross-linked chitosan and poly-L-lysine coatings were developed to encapsulate four strains
Yan Wang et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 67(10), 2202-2209 (2013-05-17)
Composite flocculants have been extensively studied and applied in recent years in order to improve the water treatment efficiency. In this study, a new composite flocculant prepared by polyaluminum chloride (PAC) and sodium alginate (SA) was used to treat dye
Chang-Gu Lee et al.
Environmental technology, 34(17-20), 2749-2756 (2014-02-18)
The objective of this study was to investigate phosphate removal using magnetic alginate-layered double hydroxide (LDH) composites. The magnetic composites were prepared by entrapping synthetic magnetic iron oxide and calcined Mg-Al LDH in polymer matrix (alginate). Results showed that the
Hnin-Ei Thu et al.
International journal of pharmaceutics, 454(1), 99-106 (2013-07-17)
In our previous study, a novel alginate-based bilayer film for slow-release wound dressings was successfully developed. We found that alginate alone yielded poor films; however, the addition of gelatine had significantly enhanced the drug dispersion as well as the physical
Chun-Xia Zhu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(20), 3479-3483 (2014-02-05)
To determine the optimum process for preparing Cinnamomi Cortex oil microspheres based on porous silicon dioxide. After porous silica dioxide adsorbed Cinnamomi Cortex oil, Cinnamomi Cortex oil microspheres were prepared by the dropping method, with sodium alginate as the skeleton
Huihui Fan et al.
Cell reports, 33(10), 108473-108473 (2020-12-10)
A role for cancer cell epithelial-to-mesenchymal transition (EMT) in cancer is well established. Here, we show that, in addition to cancer cell EMT, ovarian cancer cell metastasis relies on an epigenomic mesenchymal-to-epithelial transition (MET) in host mesenchymal stem cells (MSCs).
S Sambu et al.
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 225(11), 1092-1107 (2012-02-02)
Stem cell cryopreservation in three-dimensional (3D) scaffolds may offer better protection to cells leading to higher survival rates. However, it introduces heterogeneity in cryoprotective agent (CPA) concentrations, durations of exposure to CPA, and freezing and thawing rate within constructs. This
Bo Xiao et al.
Gastroenterology, 146(5), 1289-1300 (2014-02-08)
Nanoparticles have been explored as carriers of small interfering RNAs (siRNAs) and might be developed to treat patients with inflammatory bowel disease (IBD). Overexpression of CD98 on the surface of colonic epithelial cells and macrophages promotes the development and progression
Subin M George et al.
Biomicrofluidics, 9(2), 024116-024116 (2015-05-07)
Electro wetting-on-dielectric (EWOD) digital microfluidics (DMF) can be used to develop improved chemical screening platforms using 3-dimensional (3D) cell culture. Alginate hydrogels are one common method by which a 3D cell culture environment is created. This paper presents a study
Cuiling Du et al.
Chemistry, an Asian journal, 8(4), 736-742 (2013-02-13)
A reactive template method was used to fabricate alginate-based hydrogel microcapsules. The uniform and well-dispersed hydrogel capsules have a high drug loading capacity. After they are coated by a folate-linked lipid mixture on the surface, the capsules possess higher cell
Elena G Popa et al.
Biomacromolecules, 12(11), 3952-3961 (2011-10-06)
The present work was focused on the development and characterization of new hydrogel systems based on natural origin polymers, namely, alginate and carrageenan, into different formats and with adequate properties to sustain the viability of encapsulated cells, envisioning their application
Vijayaganapathy Vaithilingam et al.
Biomaterials, 32(33), 8416-8425 (2011-09-06)
Encapsulation of human islets may prevent their immune rejection when transplanted into diabetic recipients. To assist in understanding why clinical outcomes with encapsulated islets were not ideal, we examined the effect of encapsulation on their global gene (mRNA) and selected
Joana M Silva et al.
Acta biomaterialia, 51, 279-293 (2017-01-28)
Understanding the mechanisms controlling cell-multilayer film interactions is crucial to the successful engineering of these coatings for biotechnological and biomedical applications. Herein, we present a strategy to tune the cell adhesive properties of multilayers based on marine polysaccharides with and
Jian Hua Chen et al.
Journal of hazardous materials, 248-249, 285-294 (2013-02-13)
In this study, we prepared 3-aminopropyl-triethoxysilane (APTEOS) functionalized sodium alginate (SA) porous membrane adsorbent (APTEOS/SA) and tested its adsorption performance for removing of Cr(III) ions. The physico-chemical properties of the pristine and Cr(III) ions loaded APTEOS/SA were investigated by FT-IR
Joana M Silva et al.
Langmuir : the ACS journal of surfaces and colloids, 31(41), 11318-11328 (2015-10-01)
We investigated the pH-dependent properties of multilayered films made of chitosan (CHI) and alginate (ALG) and focused on their postassembly response to different pH environments using a quartz crystal microbalance with dissipation monitoring (QCM-D), swelling studies, ζ potential measurements, and
Trishikhi Raychoudhury et al.
Water research, 46(6), 1735-1744 (2012-01-17)
Transport and deposition of carboxymethyl cellulose (CMC)-modified nanoparticles of zero-valent iron (NZVI) were investigated in laboratory-scale sand packed columns. Aggregation resulted in a change in the particle size distribution (PSD) with time, and the changes in average particle size were
Sungjun Yoon et al.
Lab on a chip, 13(8), 1522-1528 (2013-02-22)
The importance of creating a three-dimensional (3-D) multicellular spheroid has recently been gaining attention due to the limitations of monolayer cell culture to precisely mimic in vivo structure and cellular interactions. Due to this emerging interest, researchers have utilized new
J L Lázaro-Martínez et al.
Revista de enfermeria (Barcelona, Spain), 36(11), 29-34 (2014-01-11)
High levels of bacterial load have shown a deleterious influence on wound healing. Using antimicrobial dressings can control ulcers' bioburden. The aim of our study was to evaluate the improving of infected diabetic foot ulcers due an alginate's fiber and
Yichi Xu et al.
Journal of orthopaedic translation, 18, 128-141 (2019-09-12)
Our study reports the optimization of electrospray human bone marrow stromal cell (hBMSCs)-embedded alginate-gelatin (Alg-Gel, same as following) microspheres for the purpose of their assembly in 3D-printed poly(ε-caprolactone) (PCL) scaffold for the fabrication of a mechanically stable and biological supportive tissue
Jose Luis Retes-Pruneda et al.
Environmental technology, 35(13-16), 1773-1784 (2014-06-25)
The goal of this research is to find a more effective treatment for tequila vinasses (TVs) with potential industrial application in order to comply with the Mexican environmental regulations. TVs are characterized by their high content of solids, high values
Dina Rodrigues et al.
The Science of the total environment, 461-462, 126-138 (2013-05-30)
Silica monoliths have been used for more than half a century in a wide variety of applications, such as stationary phases for microextraction fibers, capillary columns for chromatography, in the encapsulation of biomolecules for affinity chromatography and for microfluidic or
Rachelle M Kleinberger et al.
Materials science & engineering. C, Materials for biological applications, 33(7), 4295-4304 (2013-08-06)
Micropipette aspiration and confocal fluorescence microscopy were used to study the structure and mechanical properties of calcium alginate hydrogel beads (A beads), as well as A beads that were additionally coated with poly-L-lysine (P) and sodium alginate (A) to form
Sarah Duin et al.
Advanced healthcare materials, 8(7), e1801631-e1801631 (2019-03-06)
Transplantation of pancreatic islets is a promising strategy to alleviate the unstable blood-glucose control that some patients with diabetes type 1 exhibit and has seen many advances over the years. Protection of transplanted islets from the immune system can be
Ankit A Chaturvedi et al.
The Journal of surgical research, 192(2), 432-439 (2014-07-02)
Ultrapure alginate gel is promising in terms of adhesion prevention. Because anti-adhesive barriers have been shown to disturb healing of bowel anastomoses, the effect of ultrapure alginate gel on the repair of colon anastomoses was studied. In 102 male Wistar
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