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Presumed primary contact sensitization to methylisothiazolinone from paint: a chemical that became airborne.
Jeanette Kaae et al.
Contact dermatitis, 66(6), 341-342 (2012-05-10)
Julien Mutschler et al.
Toxicology in vitro : an international journal published in association with BIBRA, 23(3), 439-446 (2009-05-16)
Assessment of skin sensitization hazard of chemicals currently depends on in vivo methods. Considering the forthcoming European Union ban on in vivo testing of cosmetic/toiletry ingredients, the search for alternative non-animal approaches is an urgent challenge for investigators today. For
Leena Ackermann et al.
Contact dermatitis, 64(1), 49-53 (2010-12-21)
Antimicrobials constitute the second most common cause of contact allergy to cosmetics. Methylisothiazolinone (MI), previously always used together with methylchloroisothiazolinone (MCI), has recently been approved in the EU for use on its own in cosmetics and also various industrial products.
Determination of antimicrobial agents in non-formalin adhesives for wallpaper
Nakashima H, et al.
Journal of Health Science, 46(6), 447-454 (2000)
Allergic contact dermatitis caused by methylisothiazolinone from different sources, including 'mislabelled' household wet wipes.
Lucie Vanneste et al.
Contact dermatitis, 69(5), 311-312 (2013-10-15)
Michael D Lundov et al.
Contact dermatitis, 69(5), 271-275 (2013-10-15)
The prevalence of contact allergy to the isothiazolinone preservative methylchloroisothiazolinone (MCI) in combination with methylisothiazolinone (MI) and MI alone has increased in the last couple of years. To investigate the prevalence of contact allergy to MI, MCI/MI and benzisothiazolinone (BIT)
Identifying the optimal patch test concentration for methylchloroisothiazolinone and methylisothiazolinone.
E Davies et al.
Contact dermatitis, 60(5), 288-289 (2009-04-29)
Two cases of airborne allergic contact dermatitis caused by methylisothiazolinone in paint.
Michael D Lundov et al.
Contact dermatitis, 65(3), 176-179 (2011-08-11)
M D Lundov et al.
The British journal of dermatology, 165(6), 1178-1182 (2011-07-23)
In the early 2000s the preservative methylisothiazolinone (MI) was released as an individual preservative for industrial products and, in 2005, it was permitted for use in cosmetic products. Up until then MI had been used only in combination with methylchloroisothiazolinone
Follow-up of the monitored levels of preservative sensitivity in Europe: overview of the years 2001-2008.
Cecilia Svedman et al.
Contact dermatitis, 67(5), 312-314 (2012-10-09)
Delayed hypersensitivity to methylchloroisothiazolinone/methylisothiazolinone not detected by the baseline series of the Spanish group.
Laura Cuesta et al.
Contact dermatitis, 62(4), 250-251 (2010-05-04)
Mari Paz Castanedo-Tardana et al.
Dermatitis : contact, atopic, occupational, drug, 24(1), 2-6 (2013-01-24)
The preservative methylisothiazolinone (MI) is the American Contact Dermatitis Society Contact Allergen of the Year for 2013. Because the use of MI in cosmetics and toiletries in the United States rises, MI exposure also rises. Although it might seem likely
Magnus Bruze et al.
Contact dermatitis, 69(5), 263-270 (2013-10-15)
Methylisothiazolinone (MI) is used as a preservative in occupational and household products, and cosmetics. It is a part of the preparation of methylchloroisothiazolinone (MCI)/MI, which is patch tested in water in the European baseline series. However, this preparation fails to
Concomitant contact allergy to methylchloroisothiazolinone/methylisothiazolinone and formaldehyde-releasing preservatives.
Barry N Statham et al.
Contact dermatitis, 62(1), 56-57 (2010-02-09)
Anja P Mose et al.
Contact dermatitis, 67(5), 293-297 (2012-05-04)
Painters are among the occupational groups that most commonly experience occupational contact dermatitis, but few investigations exist concerning this occupation. To characterize painters with contact dermatitis and identify the most common allergens associated with the occupation. Materials and methods. All
R Poon et al.
Archives of toxicology, 85(11), 1419-1427 (2011-03-30)
Biocides are added to biodiesels to inhibit and remove microbial growth. The effects of 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT), a candidate biodiesel biocide, were studied using freshly isolated rat alveolar macrophages (AM) and NR8383 cell line. CMIT markedly inhibited phagocytic oxidative burst as
Irena Baranowska et al.
Journal of chromatographic science, 52(1), 88-94 (2013-01-18)
This paper reports the development of a method for simultaneously determining five preservatives in cosmetics, cleaning agents and pharmaceuticals by fast liquid chromatography. Methylisothiazolinone, methylchloroisothiazolinone, benzyl alcohol, sodium benzoate and methylparaben were separated on a Chromolith Fast Gradient reversed-phase 18e
Moist toilet paper: allergy to the nonhalogenated derivative methylisothiazolinone preservative alone.
Juan García-Gavín et al.
Archives of dermatology, 146(10), 1186-1186 (2010-10-20)
Approach for ochratoxin A fast screening in spices using clean-up tandem immunoassay columns with confirmation by high performance liquid chromatography?tandem mass spectrometry (HPLC?MS/MS)
Goryacheva.Y.I, et al.
Analytica Chimica Acta, 577(1), 38-45 (2006)
Simultaneous Determination of Ultraviolet Absorbers and Antibacterial Agents in Textiles by Ultra-High Performance Liquid Chromatography/Orbitrap High Resolution Mass Spectrometry
Wang C, et al.
World Journal of Engineering and Technology, 5(01), 1-1 (2017)
Airborne and systemic dermatitis, mimicking atopic dermatitis, caused by methylisothiazolinone in a young child.
Olivier Aerts et al.
Contact dermatitis, 68(4), 250-251 (2013-03-21)
Johannes Geier et al.
Contact dermatitis, 67(6), 334-341 (2012-09-22)
The frequency of sensitization to methylchloroisothiazolinone (MCI)/ methylisothiazolinone (MI) observed in the Information Network of Departments of Dermatology (IVDK) was constantly around 2.1% from 1998 to 2009. After that, it increased to 3.9% in 2011, paralleled by an increase in
Allergic contact dermatitis caused by methylisothiazolinone from a 'waist reduction belt'.
Wolfgang Uter et al.
Contact dermatitis, 66(6), 347-348 (2012-05-10)
Kevin H Gardner et al.
Archives of dermatology, 146(8), 886-890 (2010-06-23)
Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI), a common preservative in some brands of moist toilet paper (baby wipes and moist towelettes), has been reported to be a cause of allergic contact dermatitis. However, few cases have been reported in the United States. We report
Airborne exposure to methylchloroisothiazolinone and methylisothiazolinone from a toilet cleaner.
Michael D Lundov et al.
Contact dermatitis, 68(4), 252-253 (2013-03-21)
Paula Maio et al.
Cutaneous and ocular toxicology, 31(2), 151-153 (2011-11-05)
Several preservatives are currently allowed in cosmetic products in the EU. However, only a few of them are strongly represented on the market: formaldehyde, parabens, formaldehyde releasers and methylchoroisothiazolinone/methylisothiazolinone (MCI/MI). MCI/MI has been widely used during recent years for the
Juan García-Gavín et al.
Contact dermatitis, 63(2), 96-101 (2010-07-16)
A few cases on primary sensitization by, and occupational contact dermatitis from, methylisothiazolinone in paints and glues have been published. In cosmetics, methylisothiazoline (MI) is permitted in a concentration of 100 p.p.m., while 15 p.p.m. for the mixture of methylchloroisothiazolinone
Airborne exposure to preservative methylisothiazolinone causes severe allergic reactions.
Michael Dyrgaard Lundov et al.
BMJ (Clinical research ed.), 345, e8221-e8221 (2012-12-06)
Michael D Lundov et al.
Contact dermatitis, 64(6), 330-336 (2011-04-21)
Methylisothiazolinone (MI) used alone is a new preservative causing a high prevalence of contact allergy. The eliciting threshold of MI is unknown. The combination of MI and phenoxyethanol enhances the antimicrobial efficacy of MI. The eliciting doses of MI contact
Wolfgang Uter et al.
Contact dermatitis, 67(3), 125-129 (2012-05-09)
The preservative methylchloroisothiazolinone (MCI)/methylisothiazo- linone (MI) is an important allergen, and has thus been subject to regulation in some areas of exposure, mainly in cosmetics. To examine whether a decline in sensitization prevalence and intensity of elicitation (by the patch
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