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Ken-Pen Weng et al.
Circulation journal : official journal of the Japanese Circulation Society, 74(5), 983-989 (2010-03-27)
The literature regarding interleukin (IL)-10 polymorphisms and coronary artery lesions (CALs) in Kawasaki disease (KD) is limited. We investigated whether 3 IL-10 genetic polymorphisms (-1082 A/G, -819 T/C, and -592 A/C) are associated with development of CALs in KD. The
Andrea Palermo et al.
Clinical endocrinology, 82(6), 816-823 (2015-02-03)
There are no consistent data on the prevalence and bone status of normocalcaemic hypoparathyroidism (NHYPO) as defined by normal adjusted calcium and low PTH level. Our aim was to determine the prevalence and the metabolic bone profile of NHYPO in
Shilpa Nargund et al.
Biotechnology progress, 31(5), 1179-1186 (2015-06-23)
(13)C-metabolic flux analysis was used to understand copper deficiency-related restructuring of energy metabolism, which leads to excessive lactate production in recombinant protein-producing CHO cells. Stationary-phase labeling experiments with U-(13)C glucose were conducted on CHO cells grown under high and limiting
Elisabeth Lajeunie et al.
European journal of human genetics : EJHG, 14(3), 289-298 (2006-01-19)
Crouzon Syndrome (CS), Pfeiffer syndrome (PS) and the phenotypically related Jackson-Weiss (JW) variant are three craniosynostotic conditions caused by heterozygous mutations in Fibroblast Growth Factor Receptor (FGFR) genes. Screening a large cohort of 84 patients with clinical features of CS
Daniel J DeAngelo et al.
Blood cancer journal, 10(8), 81-81 (2020-08-10)
Adults with relapsed/refractory acute lymphoblastic leukemia (R/R ALL) have a poor prognosis, especially if disease burden is high. This post hoc analysis of the phase 3 INO-VATE trial examined the efficacy and safety of inotuzumab ozogamicin (InO) vs. standard of
Subburaman Mohan et al.
Endocrinology, 144(8), 3491-3496 (2003-07-17)
Recent studies using twins and inbred strains of mice reveal evidence for genetic mechanisms contributing to variation in circulating levels of IGF-I, IGF-II, and IGF binding protein (IGFBP)-3. To examine the hypothesis that serum IGFBP-5 levels have a strong heritable
Fabio Zattoni et al.
Abdominal radiology (New York), 43(9), 2391-2399 (2018-01-06)
To determine the performance accuracy of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) after primary tumor treatment for both bladder cancer (BC) and upper tract urothelial cancer (UTUC). To compare the accuracy of FDG PET/CT with that of contrast-enhanced-ceCT and
Naoto Takase et al.
International journal of clinical oncology, 20(3), 566-573 (2014-07-18)
Platinum agents are essential for treating gynecological malignancies, particularly ovarian cancer. However, multiple carboplatin doses may cause hypersensitivity reactions (HSRs). Carboplatin desensitization prevents life-threatening HSRs and promotes the successful completion of planned chemotherapy. Since January 2010, carboplatin desensitization was performed
Salvatore Terrazzino et al.
Pharmacogenetics and genomics, 16(11), 817-824 (2006-10-19)
The objective of the present study was to evaluate whether germline methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms as well as polymorphisms in the thymidylate synthase gene promoter, namely the variable number tandem repeat polymorphism (TS VNTR) and the intrarepeat
Joal D Beane et al.
Annals of surgical oncology, 26(5), 1429-1436 (2019-01-10)
The aim of this study was to identify factors associated with pleuropulmonary disease recurrence following cytoreductive surgery with hyperthermic intraperitoneal chemoperfusion (CRS/HIPEC) for appendiceal pseudomyxoma peritonei (PMP) and to evaluate the oncologic impact of pleuropulmonary disease recurrence compared with isolated
J Reiterová et al.
Folia biologica, 53(4), 134-137 (2007-08-21)
ADPKD is the most common hereditary renal disease. IGAN is a mesangial proliferative glomerulonephritis characterized by diffuse mesangial deposition of immunoglobulin A. ET-1 has been suggested to be a major disease-promoting factor in renal diseases. The vasoconstrictor effect of ET-1
Santiago Montes-Moreno et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 25(7), 968-982 (2012-04-28)
Here, we report a retrospective series of 47 EBV-positive diffuse large B-cell lymphoma associated with advanced age. Histopathology allowed to the identification of different histological patterns: cases with polymorphic diffuse large B-cell lymphoma (29 cases), Hodgkin-like (8 cases) and polymorphic
Agustín Conde-Agudelo et al.
American journal of obstetrics and gynecology, 209(6), 551-551 (2013-07-31)
The purpose of this study was to evaluate the efficacy and safety of transdermal nitroglycerin as a tocolytic agent in women with preterm labor. We conducted a systematic review and metaanalysis of randomized controlled trials. Thirteen studies were included (1302
Fumihiko Uchida et al.
BMC cancer, 12, 321-321 (2012-07-31)
Cell division cycle associated 3 (CDCA3), part of the Skp1-cullin-F-box (SCF) ubiquitin ligase, refers to a trigger of mitotic entry and mediates destruction of the mitosis inhibitory kinase. Little is known about the relevance of CDCA3 to human malignancy including
Inigo Espinosa et al.
The American journal of surgical pathology, 32(2), 210-218 (2008-01-29)
Gastrointestinal stromal tumors (GIST) occur primarily in the wall of the intestine and are characterized by activating mutations in the receptor tyrosine kinases genes KIT or PDGFRA. The diagnosis of GIST relies heavily on the demonstration of KIT/CD117 protein expression
Waqas Wakil et al.
PloS one, 13(7), e0192628-e0192628 (2018-07-20)
The red palm weevil Rhynchophorus ferrugineus (Olivier) is an important pest of date palms in many regions of the world. This paper reports the first survey of insecticide resistance in field populations of R. ferrugineus in Pakistan which were collected
Frank Barletta et al.
Molecular endocrinology (Baltimore, Md.), 16(2), 301-314 (2002-01-31)
When UMR-106 osteoblastic cells, LLCPK1 kidney cells, and VDR transfected COS-7 cells were transfected with the rat 24-hydroxylase [24(OH)ase] promoter (-1,367/+74) or the mouse osteopontin (OPN) promoter (-777/+79), we found that the response to 1,25dihydroxyvitamin D(3) [1,25-(OH)(2)D(3)] could be significantly
Razvan T Dadu et al.
Circulation. Heart failure, 6(5), 936-943 (2013-07-19)
Ceruloplasmin (Cp) decreases nitric oxide bioavailability in blood and has been associated with cardiovascular disease (CVD) in clinical studies. We assessed the associations between Cp and incident heart failure (HF), death, and CVD in the Atherosclerosis Risk in Communities (ARIC)
Austin M Hill et al.
International urogynecology journal, 31(8), 1537-1544 (2019-11-30)
To describe associations between postoperative genital hiatus (GH) measurements and long-term anatomical and subjective outcomes following pelvic reconstructive surgery involving apical suspension. This IRB-approved secondary analysis reports outcomes 3-7 years following robotic sacrocolpopexy (RSC) and uterosacral ligament suspension (USLS). Objective and
Dennis M McNamara et al.
Circulation, 107(12), 1598-1602 (2003-04-02)
Significant variation exists within the endothelial nitric oxide synthase (NOS3) gene that may influence cardiovascular risk. The Asp298 variant of NOS3 has a shorter half-life in endothelial cells. Given the importance of nitric oxide in the heart failure syndrome, we
Jean K Mah et al.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 38(3), 465-474 (2011-04-26)
We carried out a population-based study of dystrophin mutations in patients followed by members of the Canadian Paediatric Neuromuscular Group (CPNG) over a ten-year period. We aimed to describe the changes in diagnostic testing for dystrophinopathy and to determine the
Armando Bartolazzi et al.
The Lancet. Oncology, 9(6), 543-549 (2008-05-23)
In the USA, about 30 200 well-differentiated thyroid carcinomas were diagnosed in 2007, but the prevalence of thyroid nodules is much higher (about 5% of the adult population). Unfortunately, the preoperative characterisation of follicular thyroid nodules is still a challenge
Terence C Chua et al.
Journal of surgical oncology, 108(2), 81-88 (2013-06-06)
Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) achieves disease control within the peritoneum but recurrences occur. This study examines the outcomes of iterative CRS (iCRS) HIPEC for treatment of recurrent peritoneal metastases. Patients who underwent iCRS in a single
Benjamin J Solomon et al.
The New England journal of medicine, 371(23), 2167-2177 (2014-12-04)
The efficacy of the ALK inhibitor crizotinib as compared with standard chemotherapy as first-line treatment for advanced ALK-positive non-small-cell lung cancer (NSCLC) is unknown. We conducted an open-label, phase 3 trial comparing crizotinib with chemotherapy in 343 patients with advanced
Ioanna Gouni-Berthold et al.
Journal of hypertension, 23(2), 301-308 (2005-01-22)
The Pro12Ala and the 4a/b polymorphisms of the peroxisome proliferator-activated receptor gamma (PPARgamma) and the endothelial nitric oxide-synthase (eNOS) genes, respectively, have been associated with hypertension in some but not all studies. The purpose of this study was to investigate
Koji Tanaka et al.
International journal of stroke : official journal of the International Stroke Society, 9(8), 1045-1051 (2014-03-14)
Atrial fibrillation impairs left atrial appendage function and the thrombus formation in the left atrial appendage is a major cause of cardioembolic stroke. To evaluate the association between the volume of the left atrial appendage measured by real-time three-dimensional transesophageal
Yoshihiro Hattori et al.
Japanese journal of clinical oncology, 43(12), 1184-1189 (2013-10-31)
Pemetrexed has relatively mild toxicity and possibly can be administered long term to patients with non-small-cell lung cancer. We conducted a Phase II trial to evaluate the efficacy and safety of pemetrexed in chemotherapy-naïve elderly patients with advanced non-squamous non-small-cell
F L Gerritse et al.
European journal of cancer (Oxford, England : 1990), 49(15), 3176-3183 (2013-07-16)
Prostate cancer truly is an age-associated disease. Due to the increased life expectancy and more sensitive diagnostic techniques in the Western world, prostate cancer is diagnosed more frequently and with rapidly increasing incidence and prevalence rates. However, age above 65
Kun Qian et al.
Public health nutrition, 23(14), 2485-2493 (2020-06-11)
To determine which set of BMI cut-offs is the most appropriate to define child and adolescent obesity in urban China. A cross-sectional study was carried out between 1 November and 31 December in 2017. Community Healthcare Center in Minhang District
Lani K Clinton et al.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 27(6), 1165-1170 (2017-06-13)
The aim of this study was to determine the histopathologic characteristics of patients with endometrial carcinoma with low-volume metastases (micrometastases and isolated tumor cells) compared with macrometastases. We performed a retrospective review of patients with endometrial carcinoma. Among 350 robotic-assisted
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