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显示 1-30 共 143 条结果 关于 "75-80-9" 范围 论文
Chalinee Nuntagowat et al.
Clinical & experimental metastasis, 27(5), 295-305 (2010-04-08)
We studied the role of Neutrophil Gelatinase-associated Lipocalin (NGAL, lipocalin 2) in regulating the invasiveness of a cholangiocarcinoma cell line, RMCCA-1. RMCCA-1 cells expressed multiple forms of 25, 40, 75 and 115/135 kDa NGAL which were detected in the conditioned
R A Steingart et al.
Journal of molecular neuroscience : MN, 15(3), 137-145 (2001-04-17)
Oxidative stress is a common associative mechanism that is part of the pathogenesis of many neurodegenerative diseases. Vasoactive intestinal peptide (VIP) is a principal neuropeptide associated with normal development and aging. We have previously reported that VIP induced the secretion
Jisun Paik et al.
Experimental cell research, 303(1), 183-196 (2004-12-02)
9-Cis-retinoic acid (RA) suppresses cancer cell proliferation via binding and activation of nuclear receptors, retinoid X receptors (RXRs). In vivo, 9-cis-RA is formed through oxidation of 9-cis-retinol by cis-retinol dehydrogenase (cRDH), an enzyme that we characterized previously. Since 9-cis-RA is
Ananth Shankar et al.
British journal of haematology, 165(4), 534-544 (2014-04-24)
The purpose of this national retrospective study was to evaluate the outcome in children with relapsed or primary refractory Hodgkin lymphoma [HL] after a primary chemotherapy alone treatment strategy. Between 2000 and 2005, 80 children with relapsed [n = 69]
Lang-Song Hao et al.
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 40(1), 44-47 (2009-03-19)
To investigate the expression of glucose transporter 1 (Glut1) in human breast cancer and its relationship to proliferating cell nuclear antigen (PCNA) protein, other tumor biomarkers and clinical pathologic factors. Imunohistochemical staining (SP) was applied to measure the expression of
T Hlavaty et al.
Alimentary pharmacology & therapeutics, 22(7), 613-626 (2005-09-27)
Infliximab treatment is effective in 70-80% of patients with refractory luminal and fistulizing Crohn's disease. The effect of infliximab is ascribed to induction of apoptosis. To study whether polymorphisms in apoptosis genes predict the response to infliximab and whether they
Ravinder-Jeet Singh et al.
Stroke, 50(2), 357-364 (2019-01-01)
Background and Purpose- Intraluminal thrombus (ILT) is an uncommon finding among patients with ischemic stroke. We report clinical-imaging manifestations, treatment offered, and outcome among patients with ischemic stroke/transient ischemic attack and ILT in their cervico-cephalic arteries. Methods- Sixty-one of 3750
D Lindgren et al.
Oncogene, 25(18), 2685-2696 (2006-03-15)
We used gene expression profiling, mutation analyses of FGFR3 and TP53, and LOH analyses of chromosome 9 and the TP53 region on chromosome arm 17p, to molecularly characterize 75 Ta and T1 bladder carcinomas. We identified four major cellular processes
L A Andoh et al.
Epidemiology and infection, 144(15), 3288-3299 (2016-06-24)
Poultry are possible sources of non-typhoidal Salmonella serovars which may cause foodborne human disease. We conducted a cross-sectional study to determine the prevalence of Salmonella serovars in egg-laying hens and broilers at the farm level and their susceptibility to antimicrobials
Malik Makmur et al.
Veterinary world, 13(4), 661-668 (2019-04-01)
The aim of this study was to evaluate the effects of various combinations of tropical grass-legume species in rations on the biohydrogenation (BH) activity of unsaturated fatty acids (FAs), C18:0 composition, and fermentation profile in an in vitro rumen system.
John F Seymour et al.
British journal of haematology, 165(1), 49-56 (2014-01-29)
The efficacy and tolerance of azacitidine in higher-risk myelodysplasia with hypocellular bone marrow (BM) are unknown. This post hoc AZA-001 trial analysis assessed whether baseline BM cellularity affected the overall survival (OS) advantage demonstrated with azacitidine versus conventional care regimens
Paweł Kubalczyk et al.
Electrophoresis, 38(13-14), 1800-1805 (2017-04-19)
Fast, simple, and accurate CE method enabling determination of lipoic acid (LA) in human urine has been developed and validated. LA is a disulfide-containing natural compound absorbed from the organism's diet. Due to powerful antioxidant activity, LA has been used
Guo-Ting Tian et al.
Acta biochimica Polonica, 59(3), 407-412 (2012-09-05)
A novel laccase with a molecular mass of 64 kDa and the N-terminal sequence AIGPDDTINF was isolated from fresh fruiting bodies of the mushroom Pleurotus nebrodensis. The purification protocol comprised ion exchange chromatography on DEAE-cellulose, CM-cellulose, and Q-Sepharose, and gel
H Uchiyama et al.
Blood, 80(9), 2306-2314 (1992-11-01)
In multiple myeloma, malignant plasma cells are localized in marrow and rarely circulate in peripheral blood. To investigate the role of adhesion proteins in this process, we determined the expression and function of adhesion molecules on cell lines derived from
Caroline Robert et al.
The Lancet. Oncology, 14(8), 733-740 (2013-06-06)
Patients with metastatic melanoma, 50% of whose tumours harbour a BRAF mutation, have a poor prognosis. Selumetinib, a MEK1/2 inhibitor, has shown antitumour activity in patients with BRAF-mutant melanoma and in preclinical models when combined with chemotherapy. This study was
Tatiany Gabrielle Freire Araújo et al.
The journal of adhesive dentistry, 17(2), 117-123 (2015-04-02)
To evaluate the effect of different concentrations of monomers and solvents/diluents on the microtensile bond strength (μTBS) bond strength of experimental low-viscosity resins (infiltrants) to enamel caries-like lesions (ECLL). Flat enamel blocks obtained from sound human third molars were submitted
N Ramnath et al.
Cancer chemotherapy and pharmacology, 71(5), 1173-1182 (2013-02-26)
Preclinical studies demonstrated antiproliferative synergy of 1,25-D3 (calcitriol) with cisplatin. The goals of this phase I/II study were to determine the recommended phase II dose (RP2D) of 1,25-D3 with cisplatin and docetaxel and its efficacy in metastatic non-small-cell lung cancer.
Robert R Ishmukhametov et al.
Biochimica et biophysica acta, 1706(1-2), 110-116 (2004-12-29)
His-tagged cysteine-less F1Fo ATP synthase from Escherichia coli was purified using Ni-NTA affinity chromatography. During the purification procedure the loss of total ATPase activity did not exceed 50%, and the extent of purification was about 80-fold. The purified enzyme was
W Kroutil et al.
Journal of biotechnology, 61(2), 143-150 (1998-07-09)
A highly enantioselective, soluble epoxide from Nocardia sp. EH1 was purified to homogeneity via a four-step procedure: (i) hydrophobic interaction chromatography on Phenyl Sepharose CL-4B, (ii) anion exchange chromatography on SOURCE 30Q, followed by (iii) a second hydrophobic interaction chromatography
M S F Lie Ken Jie et al.
Chemistry and physics of lipids, 125(2), 93-101 (2003-09-23)
Methyl santalbate (methyl trans-11-octadecen-9-ynoate) from Sandal wood seed oil, Santalbum alum) was epoxidized to methyl trans-11,12-epoxy-octadec-9-ynoate (1). Treatment of compound 1 with tetrabutylammonium dihydrogentrifluoride, and boron trifluoride etherate gave the corresponding anti- (2a) (57%) and syn- (2b) (35%) fluorohydrin derivatives
Jun Zheng et al.
Hepatobiliary & pancreatic diseases international : HBPD INT, 6(4), 412-415 (2007-08-11)
Many investigators have indicated that overexpression and amplification of the human proto-oncogene c-erbB-2 is an independent prognostic factor for primary tumors. We studied expression of c-erbB-2 protein in tissues from extrahepatic cholangiocarcinoma, tissues peripheral to the carcinoma and normal bile
Aman U Buzdar et al.
The Lancet. Oncology, 14(13), 1317-1325 (2013-11-19)
Neoadjuvant chemotherapy with trastuzumab for patients with HER2-positive breast cancer can produce a pathological complete response in the breast in 30-65% of patients. We investigated the effect of the timing of trastuzumab administration with anthracycline and taxane neoadjuvant chemotherapy. This
T M Wieland et al.
Journal of animal science, 71(7), 1863-1868 (1993-07-01)
Four trials were conducted using 86, 24-h-old pigs to evaluate the utilization of medium-chain triglycerides (MCT). Effects of emulsification and amount of MCT fed were examined. After a 4-h period during which feed was withheld, pigs were force-fed MCT (containing
Bridget McCarthy Cole et al.
The Journal of organic chemistry, 61(22), 7832-7847 (1996-11-01)
Mn(III)-based oxidative free-radical cyclization of unsaturated ketones is a versatile synthetic procedure with broad applicability. For example, oxidation of cyclopentanone 1a with 2 equiv of Mn(OAc)(3).2H(2)O and 1 equiv of Cu(OAc)(2).H(2)O in AcOH at 80 degrees C for 1.5 h
Simrit Parmar et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 19(3), 474-480 (2012-12-12)
Dose intensity is important for disease control in patients undergoing allogeneic stem cell transplantation. We conducted a phase I/II controlled, adoptive, randomized study to determine the optimal dosing schedule of i.v. busulfan. Patients aged ≤75 years with advanced hematologic malignancies
Yusuke Oji et al.
Cancer science, 94(6), 523-529 (2003-06-26)
The expression levels of the Wilms' tumor gene WT1 were examined in 56 cases of head and neck squamous cell carcinoma (HNSCC) using quantitative real-time reverse transcriptase-polymerase chain reaction (RT-PCR). They included 4 cases of floor of mouth, 9 of
Jae Won Hyun et al.
Journal of clinical neurology (Seoul, Korea), 14(2), 186-190 (2018-03-06)
Patients treated with interferon-beta (IFN-β) can develop neutralizing antibodies (NAbs) against IFN-β that can negatively affect the therapeutic response. This study assessed the prevalence of NAbs and the impact of NAb positivity on the therapeutic response to IFN-β in Korean
Nandakumar Sambandam et al.
American journal of physiology. Heart and circulatory physiology, 290(1), H87-H95 (2005-09-13)
High fatty acid oxidation (FAO) rates contribute to ischemia-reperfusion injury of the myocardium. Because peroxisome proliferator-activated receptor (PPAR)alpha regulates transcription of several FAO enzymes in the heart, we examined the response of mice with cardiac-restricted overexpression of PPARalpha (MHC-PPARalpha) or
Nava Shpaisman et al.
Biomacromolecules, 13(8), 2279-2286 (2012-06-19)
A one-step synthesis of a curcumin-derived hydrogel (curcumin content of 25-75 mol %) is reported. Curcumin is incorporated into the hydrogel backbone and cross-linked through biodegradable carbonate linkages. Curcumin as a part of the polymer backbone is protected from oxidation
Hiba S Alhumaidan et al.
American journal of clinical pathology, 139(1), 110-116 (2012-12-29)
Leukoreduced blood components are commonly manufactured via filtration. There are specifications for the residual leukocyte content of any final cellular blood component but not for residual clotting factors. Leukoreduced and nonleukoreduced platelet-poor plasma products were manufactured from filtered vs unfiltered
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