761524

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关键词:'761524'

显示 1-17 共 17 条结果关于 "761524" 范围论文

DNA-Assembled Core-Satellite Upconverting-Metal-Organic Framework Nanoparticle Superstructures for Efficient Photodynamic Therapy.

He L, et al.

Small (2017)

Zwitterionic-silane copolymer for ultra stable and bright biomolecular probes based on fluorescent quantum dot nanoclusters

Dembele F, et al.

ACS Applied Materials & Interfaces (2017)

Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones.

John C Jewett et al.

Journal of the American Chemical Society, 132(11), 3688-3690 (2010-03-02)

Bioorthogonal chemical reactions, those that do not interact or interfere with biology, have allowed for exploration of numerous biological processes that were previously difficult to study. The reaction of azides with strained alkynes, such as cyclooctynes, readily forms a triazole

A SERRS/MRI multimodal contrast agent based on naked Au nanoparticles functionalized with a Gd(iii) loaded PEG polymer for tumor imaging and localized hyperthermia.

Lucio Litti et al.

Nanoscale, 10(3), 1272-1278 (2018-01-03)

Multimodal contrast agents offer new interesting diagnostic possibilities, summing the benefits of multiple imaging techniques. Magnetic resonance and optical imaging are complementary techniques. The first allows total body screening, even though it suffers from low spatial resolution and needs high

Fishing for newly synthesized proteins with phosphonate-handles.

Fleur Kleinpenning et al.

Nature communications, 11(1), 3244-3244 (2020-06-28)

Bioorthogonal chemistry introduces affinity-labels into biomolecules with minimal disruption to the original system and is widely applicable in a range of contexts. In proteomics, immobilized metal affinity chromatography (IMAC) enables enrichment of phosphopeptides with extreme sensitivity and selectivity. Here, we

A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution.

Maulik S Jani et al.

Nature chemical biology, 16(6), 660-666 (2020-03-11)

Nitric oxide synthase 3 (NOS3) produces the gasotransmitter nitric oxide (NO), which drives critical cellular signaling pathways by S-nitrosylating target proteins. Endogenous NOS3 resides at two distinct subcellular locations: the plasma membrane and the trans-Golgi network (TGN). However, NO generation

Graphene Oxide Nanosheets Modified with Single-Domain Antibodies for Rapid and Efficient Capture of Cells.

Chen GY, et al.

Chemistry?A European Journal , 21(48), 17178-17183 (2015)

Vaccination with nanoparticles combined with micro-adjuvants protects against cancer

MO Mohsen, et al.

Journal for Immunotherapy of Cancer, 7, 1-12 (2019)

Polymeric coating of silica microspheres for biological applications: suppression of non-specific binding and functionalization with biomolecules

D Brambilla, et al.

Polymers, 14, 730-730 (2022)

Ferritin Nanocages with Biologically Orthogonal Conjugation for Vascular Targeting and Imaging.

Makan Khoshnejad et al.

Bioconjugate chemistry, 29(4), 1209-1218 (2018-02-13)

Genetic incorporation of biologically orthogonal functional groups into macromolecules has the potential to yield efficient, controlled, reproducible, site-specific conjugation of affinity ligands, contrast agents, or therapeutic cargoes. Here, we applied this approach to ferritin, a ubiquitous iron-storage protein that self-assembles

Bioorthogonal click chemistries enable simultaneous spatial patterning of multiple proteins to probe synergistic protein effects on fibroblast function.

Hao Ma et al.

Biomaterials, 255, 120205-120205 (2020-06-24)

Three biorthogonal click reactions, a photoinitiated thiol-yne reaction, an azide-alkyne cycloaddition, and a methyltetrazine-transcyclooctene Diels Alder, were used to independently control the presentation of several bioactive proteins to valvular interstitial cells (VICs) in hydrogel scaffolds. Tethered fibroblast growth factor (FGF-2)

Preparation of single-and double-oligonucleotide antibody conjugates and their application for protein analytics

J Wiener, et al.

Scientific reports, 10, 1457-1457 (2020)

Investigating functional DNA grafted on nanodiamond surface using site-directed spin labeling and electron paramagnetic resonance spectroscopy.

Akiel RD., et al.

The Journal of Physical Chemistry B, 120(17), 4003-4008 (2016)

Copper-free click chemistry for dynamic in vivo imaging.

Jeremy M Baskin et al.

Proceedings of the National Academy of Sciences of the United States of America, 104(43), 16793-16797 (2007-10-19)

Dynamic imaging of proteins in live cells is routinely performed by using genetically encoded reporters, an approach that cannot be extended to other classes of biomolecules such as glycans and lipids. Here, we report a Cu-free variant of click chemistry

Visualizing metabolically labeled glycoconjugates of living cells by copper-free and fast huisgen cycloadditions.

Xinghai Ning et al.

Angewandte Chemie (International ed. in English), 47(12), 2253-2255 (2008-02-16)

Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing.

Cornelia Lorenzer et al.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 141, 37-50 (2019-05-20)

Specific cell targeting and efficient intracellular delivery are major hurdles for the widespread therapeutic use of nucleic acid technologies, particularly siRNA mediated gene silencing. To enable receptor-mediated cell-specific targeting, we designed a synthesis scheme that can be generically used to

Nanoparticles functionalized with collagenase exhibit improved tumor accumulation in a murine xenograft model.

Murty S, et al.

Particle & Particle Systems Characterization, 31(12), 1307-1312 (2014)

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