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Alex C M Oliveira et al.
Nutrients, 6(5), 2059-2076 (2014-05-27)
The beneficial health effects of a diet rich in n-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA) have been extensively researched in recent years. Marine oils are an important dietary source of n-3 LC-PUFA, being especially rich in two of
P O Nnamani et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 76(1), 68-74 (2010-06-18)
P90Gylation refers to the modification of lipid molecules by one or more phospholipid chains. Phospholipon 90G (P90G) contains about 94.0% of phosphatidylcholine stabilized with 0.1% ascorbyl palmitate and is a safe (GRAS) FDA-approved parenteral excipient with wide applications in drug
Marija Stojanović et al.
Biotechnology and applied biochemistry, 62(4), 458-466 (2014-09-17)
Fatty acid (FA) ascorbyl esters are recently emerging food, cosmetic, and pharmaceutical additives, which can be prepared in an eco-friendly way by using lipases as catalysts. Because they are amphiphilic molecules, which possess high free radical scavenging capacity, they can
Qing-Xun Song et al.
Biotechnology letters, 26(23), 1777-1780 (2005-01-27)
L-Ascorbyl oleate and L-ascorbyl linoleate were synthesized by an immobilized lipase from Candida antarctica with yields of 38% and 44%, respectively. L-Ascorbyl oleate was stable in sterile culture medium over 12 h at 37 degrees C but L-ascorbyl linoleate degraded
Bente M Jensen et al.
Journal of agricultural and food chemistry, 59(24), 13012-13017 (2011-11-11)
Whey fat has a relatively high level of unsaturated fatty acids, and as such, whey products with a high fat content are vulnerable to oxidation. The purposes of the present study were to assess the oxidative development in whey fat
Mirjam Gosenca et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 50(1), 114-122 (2013-05-07)
Liquid crystalline systems with a lamellar structure have been extensively studied as dermal delivery systems. Ascorbyl palmitate (AP) is one of the most studied and used ascorbic acid derivatives and is employed as an antioxidant to prevent skin aging. The
L Capretto et al.
International journal of pharmaceutics, 440(2), 195-206 (2012-08-14)
The current paper reports the production of polymeric micelles (PMs), based on pluronic block-copolymers, as drug carriers, precisely controlling the cellular delivery of drugs with various physico-chemical characteristics. PMs were produced with a microfluidic platform to exploit further control on
Condensation of L-ascorbic acid and medium-chain fatty acids by immobilized lipase in acetonitrile with low water content
Watanabe Y, et al.
Food Science and Technology Research, 5(2), 188-192 (1999)
Milagro Mottola et al.
Biochimica et biophysica acta, 1828(11), 2496-2505 (2013-06-29)
Ascorbyl palmitate (ASC16) is an anionic amphiphilic molecule of pharmacological interest due to its antioxidant properties. We found that ASC16 strongly interacted with model membranes. ASC16 penetrated phospholipid monolayers, with a cutoff near the theoretical surface pressure limit. The presence
Raju Jukanti et al.
Journal of microencapsulation, 28(2), 142-149 (2011-01-27)
The aim of this study is to develop ascorbyl palmitate (ASP) loaded doxorubicin (DOX) pegylated liposomes and to evaluate their targeting potential to tumor. We have prepared conventional (DL), pegylated DOX liposomes with (SDL) and without ascorbyl palmitate (SDL-A). The
Coating of peanuts with edible whey protein film containing alpha-tocopherol and ascorbyl palmitate.
J H Han et al.
Journal of food science, 73(8), E349-E355 (2008-11-21)
Physical properties of whey protein isolate (WPI) coating solution incorporating ascorbic palmitate (AP) and alpha-tocopherol (tocopherol) were characterized, and the antioxidant activity of dried WPI coatings against lipid oxidation in roasted peanuts were investigated. The AP and tocopherol were mixed
Lindomar A Lerin et al.
Ultrasonics sonochemistry, 18(5), 988-996 (2011-01-29)
This work is focused on the optimization of reaction parameters for the synthesis of ascorbyl palmitate catalyzed by Candida antarctica lipase in different organic solvents under ultrasound irradiation. The sequential strategy of experimental design proved to be useful in determining
Mostafa Nakach et al.
International journal of pharmaceutics, 476(1-2), 277-288 (2014-10-04)
This paper describes a systematic approach to select optimum stabilizer for the preparation of nano-crystalline suspensions of an active pharmaceutical ingredient (API). The stabilizer can be either a dispersant or a combination of dispersant and wetting agent. The proposed screening
Atikorn Panya et al.
Journal of agricultural and food chemistry, 63(34), 7546-7555 (2015-08-15)
Development of an antioxidant assay explaining antioxidant behaviors in complex food systems has been a challenging topic for food scientists. This research aimed to investigate antioxidant capacities and interactions of selected synthetic antioxidants and commercial natural antioxidant extracts using the
Mi Kyung Kim et al.
Colloids and surfaces. B, Biointerfaces, 103, 391-394 (2012-12-19)
The aim of this study was to produce ascorbyl palmitate (AP)-loaded nanoparticles in order to inhibit polyphenol oxidase (PPO) in bananas. AP-loaded chitosan nanoparticles were prepared using acetic acid and citric acid (denoted as CS/AA and CS/CA nanoparticles, respectively). As
Yali Yuan et al.
Analytica chimica acta, 701(2), 169-173 (2011-08-02)
Vitamin C derivatives (VCDs) have been widely used as the alternative and stable sources of vitamin C, and accordingly exhibit many new applications, such as anti-tumor and central nervous system drug delivery. In this study, their Ru(bpy)(3)(2+) electrochemiluminescence (ECL) properties
Rangrong Yoksan et al.
Colloids and surfaces. B, Biointerfaces, 76(1), 292-297 (2009-12-17)
The encapsulation of ascorbyl palmitate (AP) in chitosan particles was carried out by droplet formation via an oil-in-water emulsion, followed by droplet solidification via ionic gelation using sodium triphosphate pentabasic (TPP) as a cross-linking agent. The success of AP encapsulation
Yohko Kuge et al.
Journal of oleo science, 58(6), 295-301 (2009-05-12)
Although conjugated oils are paid much attentions to their interesting physiological properties such as anticancer, anti-arteriosclerosis, anti-hypertension activities, loss in body fat etc, there is few information on their oxidation behavior. In the present work, their oxidation behavior and oxidation
Mirjam Gosenca et al.
AAPS PharmSciTech, 11(3), 1485-1492 (2010-09-17)
The aim of this work was to test innovative approach for enhancing ascorbyl palmitate stability in microemulsions for topical application by addition of newly synthesized co-antioxidant 4-(tridecyloxy)benzaldehyde oxime (TDBO) and to investigate its antioxidant activity and finally to evaluate cytotoxicity
Oxidation and oligomerization of ethyl linoleate under the influence of the combination of ascorbic acid 6-palmitate/iron-2-ethylhexanoate
Micciche F, et al.
Applied Catalysis A: General, 297(2), 174-181 (2006)
Rupa R Sawant et al.
Pharmaceutical research, 29(2), 375-383 (2011-08-17)
To evaluate and compare anticancer therapeutic effect of palmitoyl ascorbate liposomes (PAL) and free ascorbic acid (AA). Liposomes incorporating palmitoyl ascorbate (PA) were prepared and evaluated for PA content by HPLC. To elucidate mechanism of action of cell death in
Ascorbyl palmitate and its synergism to tocopherols.
Karl-Heinz Wagner et al.
Forum of nutrition, 56, 347-348 (2005-04-06)
Michelle Olsher et al.
Analytical biochemistry, 382(1), 1-8 (2008-08-13)
We have developed a fluorescence method to examine how membrane sterol lateral organization affects the potency of antioxidants, and used this information to evaluate possible adverse effects of lipid-soluble antioxidants seen in recent clinical studies. In the presence of an
PA and fish oil.
A Carmichael
British dental journal, 212(8), 356-357 (2012-04-28)
The hydroxyl free radical reactions of ascorbyl palmitate as measured in various in vitro models
Perricone N, et al.
Biochemical and biophysical research communications, 262(3), 661-665 (1999)
Dilyana Paneva et al.
International journal of pharmaceutics, 416(1), 346-355 (2011-07-06)
The one-step incorporation of ascorbyl palmitate (AP), a widely used derivative of vitamin C, into nanofibrous mats of poly(ɛ-caprolactone) (PCL) by electrospinning was demonstrated. The incorporation of AP was attested by IR spectroscopy; the AP content was determined by thermogravimetric
Lingyan Kong et al.
Carbohydrate polymers, 111, 256-263 (2014-07-20)
In the present study, we introduce a simple method to prepare inclusion complexes by "inserting" guest molecules into preformed "empty" V-type amylose helices. Ascorbyl palmitate (AscP) was used as a model guest material to investigate the effect of solvent environment
Kyung Mi Lee et al.
Mutation research, 660(1-2), 51-56 (2008-11-26)
Although the health benefits of dietary antioxidants have been extensively studied, their potential negative effects remain unclear. L-Ascorbic acid 6-palmitate (AAP), a synthetic derivative of ascorbic acid (AA), is widely used as an antioxidant and preservative in foods, vitamins, drugs
Lipid-soluble vitamin C palmitate and protection of human high-density lipoprotein from hypochlorite-mediated oxidation.
DeMarquis O Loyd et al.
International journal of cardiology, 152(2), 256-257 (2011-08-30)
Sukyeong Kim et al.
Nature communications, 10(1), 4898-4898 (2019-10-28)
Osteoarthritis (OA) is a prevalent degenerative disease, which involves progressive and irreversible destruction of cartilage matrix. Despite efforts to reconstruct cartilage matrix in osteoarthritic joints, it has been a difficult task as adult cartilage exhibits marginal repair capacity. Here we
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