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显示 1-30 共 36 条结果 关于 "77-41-8" 范围 论文
Ana Paula de Souza da-Silva et al.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 85, 104452-104452 (2020-07-08)
Uropathogenic Escherichia coli (UPEC) is the leading cause of community-acquired urinary tract infection (CA-UTI). The increasing prevalence of CA-UTI caused by UPEC strains resistant to broad-spectrum drugs complicates clinical management of these infections. Here we assessed the prevalence of antimicrobial
J R Dunn et al.
British journal of cancer, 94(8), 1186-1193 (2006-03-30)
Angiogenesis and extracellular matrix degradation are key events in tumour progression, and factors regulating stromal-epithelial interactions and matrix composition are potential targets for the development of novel anti-invasive/antiangiogenic therapies. Here, we examine the expression of ADAMTS-8, a secreted protease with
Valérie Bonadona et al.
JAMA, 305(22), 2304-2310 (2011-06-07)
Providing accurate estimates of cancer risks is a major challenge in the clinical management of Lynch syndrome. To estimate the age-specific cumulative risks of developing various tumors using a large series of families with mutations of the MLH1, MSH2, and
C M Parsons et al.
The British journal of nutrition, 46(1), 77-86 (1981-07-01)
1. The relative potencies of three lysine, one tryptophan and six methionine analogues to their corresponding l-amino acids were determined. 2. Male poults, 9 d of age, were used in five 14 d experiments. Experimental diets were formed by adding
Flemming Dela et al.
Pflugers Archiv : European journal of physiology, 447(6), 928-933 (2003-12-20)
Ten patients with type 2 diabetes and seven controls were strength-trained with one leg for 30 min three times per week for 6 weeks. The training-induced changes in the protein densities of the Na,K-pump subunits and the Na+/H+ exchanger protein
Maynur Niyazi et al.
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 70(3), 234-242 (2003-08-21)
The p73, a homologue of the p53 tumor suppressor protein, has a pro-apoptotic activity which is induced by the c-Abl, a protein tyrosine kinase appearing in the nucleus and cytoplasm of proliferating cells. However, the role of p73 and c-Abl
Salvatore Girlando et al.
International journal of surgical pathology, 18(3), 173-176 (2010-05-13)
B-RAF V600E mutation is frequently observed in several tumors, including papillary thyroid carcinomas (PTCs), where it is considered of potential diagnostic and prognostic value. The reported prevalence of B-RAF mutation in PTCs in different Italian populations varies from 14% to
Rayyan Hemetsberger et al.
Frontiers in cardiovascular medicine, 8, 690476-690476 (2021-07-27)
Objective: We evaluated the short and long-term effect of peri-interventional dabigatran therapy on vasomotion, endothelialization, and neointimal formation in a porcine coronary artery stenting model. Background: Stenting of coronary arteries induces local inflammation, impairs vasomotion and delays endothelialization. Methods: Twenty-eight
Alexander Kohlmann et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 28(24), 3858-3865 (2010-07-21)
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic malignancy that is characterized by features of both a myeloproliferative neoplasm and a myelodysplastic syndrome. Thus far, data on a comprehensive cytogenetic or molecular genetic characterization are limited. Here, we analyzed 81
Natan D da Silva et al.
Genes, 14(1) (2023-01-22)
Patients with peripheral artery disease (PAD) have reduced muscle capillary density. Walking training (WT) is recommended for PAD patients. The goal of the study was to verify whether WT promotes angiogenesis in PAD-affected muscle and to investigate the possible role
Young Saing Kim et al.
Cancer chemotherapy and pharmacology, 73(1), 163-169 (2013-11-10)
Docetaxel, in combination with cisplatin or oxaliplatin, has demonstrated efficacy in advanced gastric cancer (AGC). This randomized, non-comparative phase II trial evaluated two weekly docetaxel-based regimens to determine which is the most promising in terms of efficacy and safety as
K S Barron et al.
Arthritis and rheumatism, 38(5), 684-689 (1995-05-01)
Although HLA-B27 is strongly associated with susceptibility to Reiter's syndrome (RS), recent data suggest that an additional modifying or susceptibility gene(s) acts in concert with HLA-B27 to contribute to disease pathogenesis. The recently described TAP genes (transporters associated with antigen
P Krustrup et al.
British journal of sports medicine, 43(11), 825-831 (2008-12-23)
To examine the effects of regular participation in recreational soccer on health profile, 36 healthy untrained Danish men aged 20-43 years were randomised into a soccer group (SO; n = 13), a running group (RU; n = 12) and a
Sidra Khan et al.
Cancers, 15(18) (2023-09-28)
Aquaporin (AQP) channels in endometrial cancer (EC) cells are of interest as pharmacological targets to reduce tumor progression. A panel of compounds, including AQP1 ion channel inhibitors (AqB011 and 5-(phenoxymethyl) furan-2-carbaldehyde, PMFC), were used to test the hypothesis that inhibition
L Tarnow et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 16(8), 1653-1656 (2001-07-31)
An XbaI polymorphism in the gene encoding the glucose transporter, GLUT-1, is associated with development of diabetic nephropathy in Chinese type 2 diabetic patients. In addition, an amino acid variant (K121Q) in the gene encoding the glycoprotein plasma cell differentiating
Hong-Mei Jiao et al.
World journal of gastroenterology, 10(19), 2836-2841 (2004-08-31)
To examine the effects of tegaserod, a serotonin (5-HT) 4 receptor partial agonist, on abdominal withdrawal reflex (AWR) to rectal distention (RD) and c-Fos expression in limbic system. Neonatal Sprague-Dawley rats randomly received colonic irritation by acetic acid from postnatal
Omar Bouhidel et al.
American journal of physiology. Heart and circulatory physiology, 295(4), H1580-H1586 (2008-08-12)
Ischemic postconditioning (IPCD) significantly reduces infarct size in healthy animals and protects the human heart. Because obesity is a major risk factor of cardiovascular diseases, the effects of IPCD were investigated in 8- to 10-wk-old leptin-deficient obese (ob/ob) mice and
Firas Aljabery et al.
BJU international, 120(3), 329-336 (2016-11-01)
To investigate the possibility of detecting sentinel lymph nodes (SNs) in patients with urinary bladder cancer (BCa) intra-operatively and whether the histopathological status of the identified SNs reflected that of the lymphatic field. We studied 103 patients with BCa pathological
Joanna M Wierońska et al.
Pharmacological reports : PR, 57(6), 734-743 (2005-12-31)
Several lines of evidence indicate that activation of group II and III metabotropic glutamate (mGlu) receptors produces anxiolytic-like effects in rodents. On the other hand neuropeptide Y (NPY) induces an anxiolytic effect in rats after intraventricular or intraamygdalar administration. Therefore
Leon Alexander Danyel et al.
Ultrasound in medicine & biology, 46(8), 1889-1895 (2020-05-23)
Transcranial color-coded duplex sonography (TCCS) and computed tomography angiography (CTA) are widely used to identify intracranial stenoses (ISs). We assessed concordance of IS grading between TCCS and CTA and proposed new TCCS criteria for severe IS ≥70%. One hundred two
Patricia H Gallego et al.
Journal of diabetes and its complications, 22(3), 191-198 (2008-04-17)
We examined genetic polymorphisms in the renin-angiotensin system (RAS) coding for angiotensin I-converting enzyme (ACE) insertion/deletion (I/D) for angiotensinogen (AGT) M235T and angiotensin II receptor type 1 (AGTR1) A1166C as predictors for the development of microalbuminuria (MA) in children with
Bellal Joseph et al.
The journal of trauma and acute care surgery, 76(5), 1301-1305 (2014-04-22)
Protocols call for the start of hormonal therapy with levothyroxine after the declaration of brain death. As the hormonal perturbations occur during the process of brain death, the role of the early initiation of levothyroxine therapy (LT) to salvage organs
Akira Kuriyama et al.
Clinical neuropharmacology, 34(6), 241-247 (2011-10-15)
To assess patient and medication factors that contribute to metronidazole toxicity. We searched PUBMED from 1965 through April 7, 2011, and performed a hand search of bibliographies. Case reports or case series reporting metronidazole-induced central nervous toxicity. Two authors independently
Marcelo Low et al.
The Lancet. Infectious diseases, 19(4), 419-428 (2019-03-09)
It is unknown whether increased use of antibiotics in a community increases the risk of acquiring antibiotic resistance by individuals living in that community, regardless of prior individual antibiotic consumption and other risk factors for antibiotic resistance. We used a
S Whittaker et al.
The British journal of dermatology, 167(3), 678-687 (2012-08-29)
Psoralen plus ultraviolet A (PUVA) is the standard treatment for early stages of mycosis fungoides. There have been no adequate randomized controlled trials with sufficient power comparing this modality with other therapies. To assess disease response and to compare the
Emmanouil Papasavvas et al.
AIDS (London, England), 23(3), 369-375 (2008-12-31)
Increased circulating levels of lipopolysaccharide (LPS) have been demonstrated in HIV-1-infected progressors. We investigated the effect of antiretroviral therapy (ART) interruptions on plasma LPS levels. Overall, 77 individuals participated in this study (51 HIV-positive and 26 healthy). Ten out of
Serap Hastürk et al.
Cancer, 94(4), 1023-1031 (2002-03-29)
Cyclooxygenase (Cox) is the main target enzyme for the nonsteroidal antiinflammatory drugs that have been shown to suppress carcinogenesis in both experimental models and epidemiologic studies. To evaluate its utility as an intermediate biomarker in bronchial chemoprevention trials, the authors
Shakil A Saghir et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46(2), 678-687 (2007-10-27)
This study determined the oral and dermal ADME of 2-amino-2-methyl-1-propanol (AMP), a substituted aliphatic alcohol used in a number of industrial and consumer products. Groups of 4 male Fischer 344 rats received either a single bolus oral or dermal dose
Xue Xin et al.
Metabolism: clinical and experimental, 52(10), 1337-1342 (2003-10-18)
The opposing effects of lipoprotein lipase (LPL) Serin447Stop (S447X) polymorphism and hepatic lipase (HL) C-514T polymorphism on serum triglyceride (TG) levels have been known. However, little is known about the interaction effect of these 2 functional gene variants on serum
Jing Tong et al.
Molecular pharmaceutics, 10(1), 360-377 (2012-11-21)
Superoxide dismutase 1 (SOD1) efficiently catalyzes dismutation of superoxide, but its poor delivery to the target sites in the body, such as brain, hinders its use as a therapeutic agent for superoxide-associated disorders. Here to enhance the delivery of SOD1
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