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Keiji Mori et al.
Journal of the American Chemical Society, 135(10), 3964-3970 (2013-02-19)
Described herein is the enantioselective synthesis of multisubstituted biaryl derivatives by chiral phosphoric acid catalyzed asymmetric bromination. Two asymmetric reactions (desymmetrization and kinetic resolution) proceeded successively to afford chiral biaryls in excellent enantioselectivities (up to 99% ee). Both experimental and
Ahmed O Alnajjar et al.
Journal of chromatographic science, 52(9), 1104-1108 (2013-09-24)
Pseudoephedrine and cetirizine have been combined in dosage forms with more therapeutic benefits when compared with single-drug treatment. The current manuscript reports the development of the first capillary zone electrophoresis (CZE) assay method for that combination. The effects of pH
Universal or Multi-mode Adhesives: Why and How?
Jorge Perdigão et al.
The journal of adhesive dentistry, 16(2), 193-194 (2014-04-24)
Jürgen Borlak et al.
BMC genomics, 16, 124-124 (2015-04-16)
Hepatocellular carcinoma (HCC) is on the rise and the sixth most common cancer worldwide. To combat HCC effectively research is directed towards its early detection and the development of targeted therapies. Given the fact that epidermal growth factor (EGF) is
Rajesh Parikh et al.
Drug delivery, 21(6), 406-411 (2013-11-13)
Tuberculosis (TB) is a chronic infectious disease with increasing incidence of drug resistance. Oral treatment for TB and multidrug resistance (MDR)-TB can have serious side effects. The causative agent of TB, Mycobacterium tuberculosis, resides in alveolar macrophages (AM). Pulmonary administration
Eri Takata et al.
Bioresource technology, 143, 53-58 (2013-06-20)
The production of monosaccharides from napier grass was investigated in the presence of acid catalysts using the hydrothermal process. When the napier grass was treated with 3 wt.% phosphoric acid at 160°C for 15min, the xylose yield reached 10.3 wt.%
Positioning self-etching adhesives: versus or in addition to phosphoric acid etching?
Claus-Peter Ernst
Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 16(1), 57-69 (2004-07-21)
Hongrui Xia et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 21(6), 906-911 (2014-02-20)
Salvianolic acid A (Sal A), an important constituent of Radix Salviae Miltiorrhizae (RSM), is effective for the treatment of myocardial infarction (MI) and coronary heart disease due to its potential in the improvement of acute myocardial ischemia. However, its content
S M El-Ashry et al.
Luminescence : the journal of biological and chemical luminescence, 30(6), 891-897 (2015-01-27)
Two simple, rapid, sensitive and precise spectrophotometric and spectrofluorimetric methods were developed for the determination of indacaterol maleate in bulk powder and capsules. Both methods were based on the direct measurement of the drug in methanol. In the spectrophotometric method
Marie-Theres Weber et al.
Caries research, 49(5), 477-487 (2015-08-01)
Antiadherent and antibacterial effects of certain plant extracts have been proven to be beneficial in preventive dentistry. In the present in situ/in vitro crossover study, the impact of plant extracts rich in polyphenols on the erosion-protective properties of the in
Samo Smrke et al.
Food chemistry, 174, 637-642 (2014-12-23)
The quality of green coffee is influenced by the degree of ripeness of the fruit at harvest. The aim of this study was to identify chemical markers differentiating between degrees of ripeness. Two coffee varieties, Catuai and Tipica, from the
D S Morais et al.
Biomedical materials (Bristol, England), 10(5), 055008-055008 (2015-09-24)
The aim of this work was to develop a bioactive bone substitute with an effective antibacterial ability based on a cerium (Ce) doped glass-reinforced hydroxyapatite (GR-HA) composite. Developed composites were physicochemically characterized, using x-ray diffraction (XRD) analysis, SEM, energy dispersive
Robert W Gene et al.
Journal of immunological methods, 416, 29-39 (2014-12-03)
The need for rapid and easy technologies for the detection of food-borne and environmental pathogens is essential for safeguarding the health of populations. Furthermore, distribution of tainted food and water can have consequences which can affect whole economies. Antibodies and
Jacqueline R Gimmler et al.
Veterinary dermatology, 26(6), 411-416 (2015-08-20)
Terbinafine (TBF) is known to concentrate and persist in human skin. Its use is increasing in veterinary medicine, but there are limited data concerning its tissue concentration and efficacy in dogs. (i) Describe TBF accumulation in canine skin; (ii) Integrate
Kwang-Jin Kim et al.
Bone, 81, 208-216 (2015-07-26)
Bone sustains its structure through dynamic interaction between osteoblastic cells and osteoclastic cells. But imbalance may lead to osteoporosis caused by overactivated osteoclast cells that have bone-resorbing function. Recently, herbs have been researched as major sources of medicines in many
Youssef Bennis et al.
International journal of pharmaceutics, 495(2), 956-962 (2015-10-11)
Epirubicin is widely used for conventional transcatheter arterial chemoembolization (cTACE) in patients with hepatocellular-carcinoma. However, there is no data about its stability in solution at concentration higher than 2 mg/L, yet needed when mixing it with a standard volume of
Atsushi Saito et al.
Science translational medicine, 7(313), 313ra181-313ra181 (2015-11-13)
Pulmonary alveolar microlithiasis (PAM) is a rare, autosomal recessive lung disorder associated with progressive accumulation of calcium phosphate microliths. Inactivating mutations in SLC34A2, which encodes the NPT2b sodium-dependent phosphate cotransporter, has been proposed as a cause of PAM. We show
Chen Fan et al.
Food chemistry, 174, 446-451 (2014-12-23)
In-situ ionic liquid-dispersive liquid-liquid microextraction (IL-DLLME) method was developed as a pretreatment method for the detection of six chlorophenols (CPs) in honey samples. The hydrophobic ionic liquid [C4MIM][NTf2], formed in-situ by the hydrophilic ionic liquid [C4MIM][BF4] and the ion exchange
Zebasil Tassew et al.
SpringerPlus, 4, 649-649 (2015-11-07)
Tobacco is a valuable cash crop. It is the most widely grown non-food crop in the world. Tobacco use is widespread due to its addictive nature of its main constituent nicotine. Therefore, the knowledge of nicotine level in tobacco is
Li-Bo Li et al.
Neuropharmacology, 91, 23-33 (2014-12-09)
Serotonin2A (5-HT2A) receptors are highly expressed in the medial septum-diagonal band of Broca complex (MS-DB), especially in parvalbumin (PV)-positive neurons linked to hippocampal theta rhythm, which is involved in cognition. Cognitive impairments commonly occur in Parkinson's disease. Here we performed
A A Gryshchenko et al.
Bioorganic & medicinal chemistry, 23(9), 2287-2293 (2015-03-31)
Fibroblast grow factor receptor 1 (FGFR1) is an important anti-cancer target that plays crucial role in oncogenesis and oncogenic angiogenesis. The structure-activity relationship (SAR) of N-phenylthieno[2,3-d]pyrimidin-4-amines was investigated. Binding of active compounds with FGFR1 kinase was analyzed by molecular modeling
Tiago A Miranda et al.
Malaria journal, 14, 29-29 (2015-01-30)
Chloroquine and primaquine are the first-line treatment recommended by World Health Organization for malaria caused by Plasmodium vivax. Since the problem of counterfeit or substandard anti-malarials is well established all over the world, the development of rapid and reliable methods
Surya Prakash Rao Pydimarry et al.
Journal of chromatographic science, 52(1), 42-51 (2012-12-22)
A simple, sensitive, precise and accurate stability-indicating ultra-performance liquid chromatography (UPLC) method was developed for the quantitative determination of the purity of the active pharmaceutical ingredient of milnacipran hydrochloride (MCP) and its pharmaceutical dosage form in the presence of its
Dilusha M Fernando et al.
BMC complementary and alternative medicine, 15, 398-398 (2015-11-08)
Macrofungi have an established history of use in traditional oriental medicine. Anthracophyllum lateritium is a terrestrial macrofungus found in the dry zone forest reserves in Sri Lanka. Yet there are no scientific reports on bioactive properties of this species. Hence
Li-Hong Ye et al.
Analytical and bioanalytical chemistry, 407(6), 1763-1773 (2014-12-21)
A novel effervescent-salt-assisted dispersive micro-solid-phase extraction using mesoporous hybrid materials was developed for the extraction of minute traces of constituents in complicated plant preparations. In this study, a special tablet containing carbon dioxide sources (sodium dihydrogenphosphate and sodium carbonate) and
Noemi González-Abuín et al.
Food & function, 5(9), 2357-2364 (2014-08-05)
We have previously reported that procyanidins, a class of flavonoids, improve glycemia and exert an incretin-like effect, which was linked to their proven inhibitory effect on the dipeptidyl-peptidase 4 (DPP4) activity. However, their actual effect on incretin levels has not
Amit Naskar et al.
Journal of pineal research, 58(3), 262-274 (2015-01-30)
L-3,4-dihydroxyphenylalanine (L-DOPA) reduces symptoms of Parkinson's disease (PD), but suffers from serious side effects on long-term use. Melatonin (10-30 mg/kg, 6 doses at 10 hr intervals) was investigated to potentiate L-DOPA therapeutic effects in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism in mice. Striatal
Hichem Sebai et al.
Journal of medicinal food, 18(2), 241-249 (2014-08-12)
The authors aimed in the present study to assess the protective effect of Rosmarinus officinalis essential oils (ROEO) and Lavandula stoechas essential oils (LSEO) against reproductive damage and oxidative stress in alloxan-induced diabetic male rats. Essential oil samples were obtained
Marzieh Rashidipour et al.
Journal of AOAC International, 97(4), 1109-1113 (2014-08-26)
Matrix solid-phase dispersion (MSPD) methodology as a quick and easy extraction method has been developed to extract oleuropein from Olea europaea leaves. This method has been compared with conventional maceration and Soxhlet extraction (SOXE) methods. Variables affecting MSPD, such as
Takahiro Kanamori et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 985, 142-148 (2015-02-16)
An analytical method for catecholamines and related compounds using hydrophilic interaction liquid chromatography (HILIC) with native fluorescence detection has been developed. We found that ZIC-cHILIC with phosphorylcholine was suitable for the separation of catechol compounds with good peak shapes among
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