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Katarina Hostanska et al.
The Journal of pharmacy and pharmacology, 66(11), 1606-1614 (2014-09-02)
Extracts of the tubers of Harpagophytum procumbens (devil's claw, DC) inhibit different proinflammatory mediators important in the pathophysiology of osteoarthritis. Many plant-derived preparations interfere with cytochrome P450 liver enzymes, which influence their different biological activities. Therefore, the present study was
Knut Fredrik Seip et al.
Journal of chromatography. A, 1347, 1-7 (2014-05-06)
Electromembrane extraction (EME) was performed on samples containing substantial amounts of NaCl to investigate how the presence of salts affected the recovery, repeatability, and membrane current in the extraction system. A group of 17 non-polar basic drugs with various physical
Iwona Kowalska et al.
Journal of agricultural and food chemistry, 62(46), 11200-11208 (2014-10-31)
Fourteen phenolic compounds (flavonoids and phenolic acids) were isolated and 19 were identified in the aerial parts of Triticum aestivum L. The structures of these compounds were established on the basis of the data obtained by electrospray ionization-mass spectrometry (ESI-MS)
Izabela Ferreira Gontijo de Amorim et al.
PloS one, 6(11), e27679-e27679 (2011-12-06)
The aim of the present study was to investigate TLR2 expression in peripheral blood monocytes from dogs naturally infected with Leishmania (Leishmania) infantum to determine whether it correlates with CD11b/CD18 (CR3) expression, and to evaluate the potential of dogs as
Priyanka Gupta et al.
Australian orthodontic journal, 28(2), 240-244 (2013-01-12)
The purpose of this study was to evaluate the ultramorphology and surface roughness of permanent tooth enamel after various post-stripping polishing methods. Sixty extracted, permanent lower incisors were randomly assigned to two groups (Group A and Group B). Group A
Nayara Cristina Perez de Albuquerque et al.
Journal of pharmaceutical and biomedical analysis, 109, 192-201 (2015-03-18)
Zopiclone (ZO) is a chiral drug that undergoes extensive metabolism to N-desmethylzopiclone (N-Des-ZO) and zopiclone-N-oxide (N-Ox-ZO). Pharmacological studies have shown (S)-N-Des-ZO metabolite presents anxiolytic activity and a patent for this metabolite was requested for anxiety treatment and related disorders. In
Mustafa Demirci et al.
Clinical oral investigations, 19(9), 2187-2199 (2015-03-25)
To evaluate the medium-term clinical performance of direct composite build-ups for diastema closures and teeth recontouring using a nano and a nanohybrid composite in combination with three- or two-step etch-and-rinse adhesives following treatment with fixed orthodontic appliances. A total of
Yingying Wen et al.
Journal of chromatography. A, 1368, 18-25 (2014-12-03)
A modified Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) method based on the dispersive solid-phase extraction (dSPE) combined with high performance liquid chromatography (HPLC) was developed for the determination of non-steroidal estrogens in water samples. In this study, graphene
Diurnal variation in the levels of glucose and related substances in healthy and diabetic subjects during starvation.
C Faiman et al.
Clinical science, 32(1), 111-126 (1967-02-01)
Chen Shi et al.
International journal of pharmaceutics, 479(1), 41-51 (2014-12-17)
The study aims at designing a nanoparticle-based delivery system to improve the efficacy of the natural compound tetrandrine against lung cancer. Nanoparticles from poly(lactic-co-glycolic acid) (PLGA) were prepared by the emulsion solvent diffusion method and characterized for their physicochemical properties
Melissa Aline da Silva et al.
The journal of contemporary dental practice, 14(1), 9-13 (2013-04-13)
This study evaluates bond strength between dentin and composite using adhesives with different solvents to dry and wet dentin. Ninety bovine incisors were used; the vestibular surfaces were worn by the exposure of an area with a diameter of 4
Mamta Bishnoi et al.
Journal of drug targeting, 22(9), 805-812 (2014-06-24)
Abstract Background: In intra-articular drug delivery, there are number of shortcomings such as lymphatic drainage from the synovial cavity, frequent dosing, adverse side effects and patient discomfort in the management of osteoarthritis (OA). This research work reports the development and
Arminja N Kettenbach et al.
Journal of proteomics, 114, 48-60 (2014-12-03)
The study of cellular signaling remains a significant challenge for translational and clinical research. In particular, robust and accurate methods for quantitative phosphoproteomics in tissues and tumors represent significant hurdles for such efforts. In the present work, we design, implement
Shashwati U Atwe et al.
Journal of controlled release : official journal of the Controlled Release Society, 194, 45-52 (2014-08-26)
Oral vaccination can offer a painless and convenient method of vaccination. Furthermore, in addition to systemic immunity it has potential to stimulate mucosal immunity through antigen-processing by the gut-associated lymphoid tissues. In this study we propose the concept that pollen
Toshihiro Takashima et al.
Journal of photochemistry and photobiology. B, Biology, 152(Pt A), 139-145 (2015-02-05)
One challenge in artificial photosynthetic systems is the development of active oxygen evolution catalysts composed of abundant elements. The oxygen evolution activities of manganese pyrophosphate compounds were examined in electrochemical and photochemical experiments. Electrocatalysis using calcium-manganese pyrophosphate exhibited good catalytic
Roshan Uthappa et al.
The journal of contemporary dental practice, 13(6), 756-759 (2013-02-14)
The purpose of the study was to compare two different commercial bleaching agents, Opalescence with Colgate Platinum, and 30% phosphoric acid used as aggressive agent on the morphology of human enamel. Ten freshly extracted, noncarious, human maxillary central incisors extracted
Silvia Reina et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 44(10), 876-883 (2015-03-03)
We demonstrate that serum immunoglobulin G (IgG) directed against glandular M3 muscarinic acetylcholine receptors (M₃mAChR) and pilocarpine triggers the increment of superoxide dismutase (SOD) and catalase (CAT) and the production of nitric oxide (NO) and prostaglandin E₂(PGE₂). Enzyme-linked immunosorbent assay
I Yavuz et al.
European journal of paediatric dentistry : official journal of European Academy of Paediatric Dentistry, 14(1), 42-46 (2013-04-20)
This was to investigate if dental restorations on human, dog and bovine primary teeth are equitable for microleakage analysis, and the respective marginal adaptation deficiency in in vitro conditions. In order to determine the level of microleakage in Class V
Jannet Kamoun et al.
Biochimica et biophysica acta, 1851(2), 129-140 (2014-12-03)
Yarrowia lipolytica is a lipolytic yeast possessing 16 paralog genes coding for lipases. Little information on these lipases has been obtained and only the major secreted lipase, namely YLLIP2, had been biochemically and structurally characterized. Another secreted lipase, YLLIP8, was
Chong-hao Bi et al.
Bioresource technology, 185, 185-193 (2015-03-17)
A novel process was developed for converting scum, a waste material from wastewater treatment facilities, to biodiesel. Scum is an oily waste that was skimmed from the surface of primary and secondary settling tanks in wastewater treatment plants. Currently scum
Laura Kervezee et al.
The AAPS journal, 16(5), 1029-1037 (2014-06-12)
Nearly all bodily processes exhibit circadian rhythmicity. As a consequence, the pharmacokinetic and pharmacodynamic properties of a drug may also vary with time of day. The objective of this study was to investigate diurnal variation in processes that regulate drug
Li Yan Chan et al.
The Journal of organic chemistry, 78(17), 8826-8832 (2013-08-07)
A simple and efficient method is developed for Pd-catalyzed ortho-acetoxylation using organophosphates, namely, benzylic phosphonic and aryl phosphoric monoacids, as the directing group.
Bryan A Wilson et al.
American journal of physiology. Renal physiology, 308(6), F594-F601 (2015-01-09)
Angiotensin 1-7 [ANG-(1-7)] is expressed within the kidney and exhibits renoprotective actions that antagonize the inflammatory, fibrotic, and pro-oxidant effects of ANG II. We previously identified an peptidase that preferentially metabolized ANG-(1-7) to ANG-(1-4) in the brain medulla and cerebrospinal
Javad Tashkhourian et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 152, 119-125 (2015-07-24)
A rapid, simple and inexpensive spectrofluorimetric sensor for determination of doxycycline based on its interaction with thioglycolic acid-capped cadmium telluride quantum dots (TGA/CdTe QDs) has been developed. Under the optimum experimental conditions, the sensor exhibited a fast response time of
Li Chu et al.
DNA and cell biology, 34(3), 178-188 (2015-01-22)
The traditional Chinese medicinal formula BDL301 has been used to inhibit inflammation for hundreds of years. The development of colorectal cancer and chronic inflammation are closely related. In this study, we investigated whether BDL301 could inhibit tumor growth. We found
Xabier Osteikoetxea et al.
PloS one, 10(3), e0121184-e0121184 (2015-03-24)
In recent years the study of extracellular vesicles has gathered much scientific and clinical interest. As the field is expanding, it is becoming clear that better methods for characterization and quantification of extracellular vesicles as well as better standards to
Joanna Witos et al.
The Analyst, 140(9), 3175-3182 (2015-03-10)
In this work, a method to study and analyze the interaction data in free solution by exploiting partial filling affinity capillary electrophoresis (PF-ACE) followed by adsorption energy distribution calculations (AED) prior model fit to adsorption isotherms will be demonstrated. PF-ACE-AED
Sonika Batra et al.
Biomedical chromatography : BMC, 28(6), 815-825 (2014-05-28)
Enantiomeric separation of racemic mexiletine and fluoxetine was achieved using three chiral derivatizing reagents (CDRs) based on (S)-naproxen. Diastereomers were synthesized by reaction of mexiletine or fluoxetine with the CDRs and were separated on a C18 column under reversed-phase conditions
N A Bul'enkov et al.
Biofizika, 58(1), 8-26 (2013-05-09)
The system-forming role of the surface layer of water in the process of formation of ultrathin layers from the epoxide oligomer and triethylenetetramine or phosphotungstic acid on the surface of the aqueous phase is shown. Previously, this process was studied
Tarek A Ahmed et al.
AAPS PharmSciTech, 15(3), 772-780 (2014-03-22)
The objective of this study was to investigate the sustained release of a hydrophilic drug, montelukast (MK), from two biodegradable polymeric drug delivery systems, in situ implant (ISI) and in situ microparticles (ISM). N-Methyl pyrrolidone (NMP), dimethyl sulfoxide (DMSO), triacetin
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