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Gabriella M Anic et al.
Lung cancer (Amsterdam, Netherlands), 86(3), 297-303 (2014-12-03)
Vitamin D may prolong cancer survival by inhibiting tumor progression and metastasis, however, there are limited epidemiologic studies regarding the association between circulating 25-hydroxyvitamin D (25(OH)D) and lung cancer survival. The aim of this study was to examine the relationship
Zelieann R Craig et al.
Biology of reproduction, 88(1), 23-23 (2012-12-18)
Di-n-butyl phthalate (DBP) is present in many consumer products, such as infant, beauty, and medical products. Several studies have shown that DBP causes reproductive toxicity in rodents, but no studies have evaluated its effects on ovarian follicles. Therefore, we used
Rebecca A Clewell et al.
Reproductive toxicology (Elmsford, N.Y.), 35, 70-80 (2012-09-05)
Male rat sexual development was evaluated after dietary administration of 0, 760, 3800, 11,400 ppm diisononyl phthalate (DiNP) and 7600 ppm dibutyl phthalate (DBP) from gestation day (GD) 12 to postnatal day (PND) 14. Maternal weight was reduced on GD
Biqi Wang et al.
Twin research and human genetics : the official journal of the International Society for Twin Studies, 18(2), 158-170 (2015-03-07)
The genetic contribution of blood pressure and heart rate (HR) varied widely between studies. Demographic factors such as ethnicity, age and/or sex might explain some of the heterogeneity. We performed a systematic review focusing on four phenotypes: systolic blood pressure
An approach for integrating toxicogenomic data in risk assessment: the dibutyl phthalate case study.
Susan Y Euling et al.
Toxicology and applied pharmacology, 271(3), 324-335 (2013-03-30)
An approach for evaluating and integrating genomic data in chemical risk assessment was developed based on the lessons learned from performing a case study for the chemical dibutyl phthalate. A case study prototype approach was first developed in accordance with
Ming-sheng Lan et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(2), 229-231 (2012-07-25)
To study the chemical constituents of the ethyl acetate extract from Blumea aromatica. Column chromatographic techniques were used for the isolation and purification. Spectroscopic techniques were used for the identification of structures. Seven compounds were isolated from the ethyl acetate
Galal M El Mahrouk et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(3), 1005-1011 (2014-12-03)
The present study deals with the inclusion or incorporation of hot-melts into buccoadhesive patches. Our aim is to develop a patient-friendly dosage form that is capable of extending release of short elimination half-life drugs so to decrease dosing frequency and
Maristela Böhlke et al.
Clinical and experimental hypertension (New York, N.Y. : 1993), 37(3), 235-240 (2014-10-15)
Approximately 30% of the chronic kidney disease patients using recombinant human erythropoietin (rhuEPO) have an increase in blood pressure (BP). Its mechanism and whether it depends on renal function remain unclear. There is early evidence that acetylsalicylic acid (ASA) prevents
Xiaowei Liu et al.
Environmental pollution (Barking, Essex : 1987), 184, 262-270 (2013-10-01)
The first nationwide survey of six phthalic acid esters (PAEs) (diethyl phthalate (DEP); dimethyl phthalate (DMP); di-n-butyl phthalate (DBP); butyl benzyl phthalate (BBP); bis(2-ethylhexyl) phthalate (DEHP); di-n-octyl phthalate (DnOP)) in source waters was conducted in China. The results showed these
Guoxing Wang et al.
PloS one, 10(3), e0121968-e0121968 (2015-03-24)
Previous studies have demonstrated that the cell surface receptor Slamf1 (CD150) is requisite for optimal NADPH-oxidase (Nox2) dependent reactive oxygen species (ROS) production by phagocytes in response to Gram- bacteria. By contrast, Slamf8 (CD353) is a negative regulator of ROS
Shukang Wang et al.
BMC public health, 15, 7-7 (2015-01-18)
Obesity is a major independent risk factor for chronic diseases such as hypertension and coronary diseases, it might not be only related to the amount of body fat but its distribution. The single body mass index (BMI), waist circumference (WC)
Sheng-Feng Hung et al.
PloS one, 9(6), e100321-e100321 (2014-06-27)
Effervescent multiple-unit floating drug delivery systems (muFDDSs) consisting of drug (lorsartan)- and effervescent (sodium bicarbonate)-containing pellets were characterized in this study. The mechanical properties (stress and strain at rupture, Young's modulus, and toughness) of these plasticized polymeric films of acrylic
Qiliu Peng et al.
PloS one, 9(12), e116026-e116026 (2014-12-30)
Polymorphisms of genes encoding components of the vitamin D pathway including vitamin D receptor (VDR) and vitamin D binding protein (DBP) have been widely investigated because of the complex role played by vitamin D in cancer tumorogenesis. In this study
Hermann Fromme et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 53, 272-280 (2012-12-19)
Phthalates as well as di-(2-ethylhexyl) adipate (DEHA) are used as plasticizers in diverse applications and are of toxicological concern. The study was conducted with a study population of 25 German subjects aged between 15 and 21 months. Overall, 16 phthalates
Stephane R Chartier et al.
Pain, 155(11), 2323-2336 (2014-09-10)
Skeletal injury is a leading cause of chronic pain and long-term disability worldwide. While most acute skeletal pain can be effectively managed with nonsteroidal anti-inflammatory drugs and opiates, chronic skeletal pain is more difficult to control using these same therapy
Zhixing He et al.
Bioresource technology, 128, 526-532 (2012-12-04)
HD-1, a stable microbial consortium capable of mineralizing di-n-butyl phthalate (DBP), was developed from activated sludge. The dominant microorganisms in the consortium, Gordonia sp., Burkholderia sp. and Achromobacter sp., were identified by denaturing gradient gel electrophoresis (DGGE). The consortium could
Li Zhang et al.
Journal of chromatography. A, 1386, 22-30 (2015-02-24)
A new analytical method was established and validated for the analysis of 19 substances of very high concern (SVHCs) in textiles, including phthalic acid esters (PAEs), organotins (OTs), perfluorochemicals (PFCs) and flame retardants (FRs). After ultrasonic extraction in methanol, the
Luciano Candilio et al.
Heart (British Cardiac Society), 101(3), 185-192 (2014-09-26)
Remote ischaemic preconditioning (RIPC), using brief cycles of limb ischaemia/reperfusion, is a non-invasive, low-cost intervention that may reduce perioperative myocardial injury (PMI) in patients undergoing cardiac surgery. We investigated whether RIPC can also improve short-term clinical outcomes. One hundred and
Harpreet Bhatia et al.
Aquatic toxicology (Amsterdam, Netherlands), 149, 103-115 (2014-03-01)
Phthalic acid esters (PAEs) are a class of synthetic industrial chemicals commonly found in the aquatic environment worldwide. PAEs have been recognised as anti-androgens in male mammals but little is known about their endocrine disrupting effects in fish. This study
B Ray et al.
Bratislavske lekarske listy, 113(10), 577-582 (2012-10-26)
Phthalates are a class of industrial compounds with an array of toxicological properties used in day to day life. Diisobutyl phthalate on (DIBP) is used as an additive to keep the plastics soft or flexible (plasticizer) in nitrocellulose plastic, nail
I Shiue
European journal of neurology, 20(4), 728-731 (2012-09-13)
Associations between plastic-associated chemicals, such as bisphenol A, and cardiovascular disease have begun to emerge in the current century. However, the relationship between urine phthalates and risk of stroke is unclear. It was aimed to study the relationship between urine
Simon M Plummer et al.
Toxicological sciences : an official journal of the Society of Toxicology, 132(2), 443-457 (2013-01-30)
Previous analysis of in utero dibutylphthalate (DBP)-exposed fetal rat testes indicated that DBP's antiandrogenic effects were mediated, in part, by indirect inhibition of steroidogenic factor 1 (SF1), suggesting that peroxisome proliferator-activated receptor alpha (PPARα) might be involved through coactivator (CREB-binding
Richard Ivell et al.
Asian journal of andrology, 15(2), 261-268 (2013-01-15)
Maternal exposure to estrogenic xenobiotics or phthalates has been implicated in the distortion of early male reproductive development, referred to in humans as the testicular dysgenesis syndrome. It is not known, however, whether such early gestational and/or lactational exposure can
Shabnam Shokouhi et al.
Canadian journal of diabetes, 39(1), 65-72 (2014-10-06)
The peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha) gene could play a role in the onset of type 2 diabetes mellitus. The aim of this study was to explore the possible associations among polymorphisms Gly482Ser, Thr394Thr and Thr528Thr of the PGC-1alpha
Jose-Alberto Palma et al.
Movement disorders : official journal of the Movement Disorder Society, 30(5), 639-645 (2015-02-14)
Orthostatic hypotension (OH) is frequent in patients with Parkinson's disease (PD) and can occur with or without symptoms. Pharmacological treatments are effective, but often exacerbate supine hypertension. Guidelines exist for the diagnosis, but not for the treatment of OH. We
Tiziana Di Chiara et al.
Journal of clinical hypertension (Greenwich, Conn.), 17(5), 332-337 (2015-02-24)
This study was designed to evaluate the impact of educational status on global cardiovascular risk in a southern Italian urban population. The study population consisted of 488 consecutive outpatients aged 18 years and older. Educational status was categorized according to the
Alexandros Kasiakogias et al.
Journal of hypertension, 33(2), 393-400 (2014-10-17)
Beneficial effects of continuous positive airway pressure (CPAP) on both blood pressure (BP) levels and variability have been documented in patients with obstructive sleep apnoea (OSA). We investigated the relevant impact of different dosing times of antihypertensive drugs beyond CPAP
George G S Sandor et al.
International journal of cardiology, 179, 470-475 (2014-12-04)
Patients with Marfan (MFS) and Loeys-Dietz (LDS) syndromes have been shown to have abnormal aortic biophysical properties. The purpose of this study was to compare the effects of 12-months of therapy with atenolol or losartan on vascular function in young
Sarah Moody et al.
Endocrinology, 154(9), 3460-3475 (2013-06-15)
Phthalates are plasticizers with widespread industrial, domestic, and medical applications. Epidemiological data indicating increased incidence of testicular dysgenesis in boys exposed to phthalates in utero are reinforced by studies demonstrating that phthalates impair fetal rodent testis development. Because humans are
Gang Ren et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(1), 62-64 (2012-06-28)
To study the chemical constituents of the roots of Dendropanax chevalieri. The constituents were isolated by column chromatography with silica gel, Sephadex LH-20 gel and RP-18. Their structures were elucidated by analysis of spectral data and physicochemical properties. Eight compounds
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