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Nicolas Golse et al.
HPB : the official journal of the International Hepato Pancreato Biliary Association, 22(6), 900-910 (2019-11-18)
To address the results of resection for hepatocellular carcinoma (HCC) in human immunodeficiency virus (HIV)-carriers, and to compare them against survival after liver transplantation (LT). All patients with HIV and HCC listed for LT (candidates = LTc+) or resection (LR+) between 2000
The p53 codon 72 arg/arg homozygous women in central Italy are at increased risk for HPV infections.
Marco Ciotti et al.
Anticancer research, 26(5B), 3745-3748 (2006-11-11)
The oncoprotein E6 binds to and degrades the p53 tumor suppressor protein, with different efficacy depending on the p53 codon 72 (arg/pro) polymorphism. The arg/arg allele has been shown to increase the risk for cervical cancer. Fifty-eight women infected with
Eric Druyts et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 56(7), 961-967 (2012-12-18)
A systematic review and meta-analysis were conducted to examine the efficacy and safety of pegylated interferon (peg-IFN) alfa-2a and peg-IFN alfa-2b plus ribavirin (RBV) in children and adolescents with chronic hepatitis C virus (HCV). Medline, Embase, and Cochrane Central Register
B Mertens et al.
Gene, 176(1-2), 273-274 (1996-10-17)
The nucleotide (nt) sequence encoding the bovine homologue of interleukin-5 (boIL-5) was determined. Total cDNA generated from stimulated bovine peripheral blood lymphocytes was used to amplify the boIL-5 gene using primers based on the 5' and 3' untranslated regions of
Sriram Venneti et al.
The American journal of surgical pathology, 35(10), 1463-1472 (2011-09-17)
Malignant rhabdoid tumors (MRTs) are highly aggressive pediatric tumors associated with loss of expression of SMARCB1, commonly occurring in the central nervous system [referred to as atypical teratoid/rhabdoid tumors (AT/RTs)] and in the kidney and soft tissues. Histologically, MRTs are
R Jakobi et al.
The Journal of biological chemistry, 271(11), 6206-6211 (1996-03-15)
The serine/threonine protein kinase PAK I (p2l-activated protein kinase), a ubiquitous multipotential protein kinase of 58-60 kDa, has been shown to have cytostatic properties. Data from our laboratory show that PAK I is highly active in oocytes and quiescent and
Shahriar Koochekpour et al.
Genes, chromosomes & cancer, 44(4), 351-364 (2005-08-05)
We identified prosaposin (PSAP) as a secreted protein expressed in androgen-independent (AI) prostate cancer cells by cloning/sequencing, after probing a PC-3 cDNA library expressed in the lambdaTriplEx phagemid expression vector with a polyclonal rabbit antibody generated against pooled human seminal
Biodegradation of kerosene: Study of growth optimization and metabolic fate of P. janthinellum SDX7.
Shamiyan R Khan et al.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 46(2), 397-406 (2015-08-15)
Penicillum janthinellum SDX7 was isolated from aged petroleum hydrocarbon-affected soil at the site of Anand, Gujarat, India, and was tested for different pH, temperature, agitation and concentrations for optimal growth of the isolate that was capable of degrading upto 95%
N J Parker et al.
Genomics, 27(2), 280-285 (1995-05-20)
Ribonucleotide reductase comprises two nonidentical protein subunits R1 and R2, both of which are required for enzyme activity and show cell cycle-dependent regulation. The TATA-less promoter of the human RRM1 gene (encodes R1 protein) was examined with reference to regulatory
Markus Mezger et al.
Blood, 111(2), 534-536 (2007-10-25)
Patients after allogeneic stem-cell transplantation (alloSCT) have an increased risk for invasive aspergillosis (IA). Here, recipients of an allograft with IA (n=81) or without IA (n=58) were screened for 84 single nucleotide polymorphisms in 18 immune relevant genes. We found
Marcel Dautzenberg et al.
The Journal of physiology, 589(Pt 19), 4731-4744 (2011-08-10)
Nitric oxide (NO) blunts the myogenic response (MR) in renal blood flow (RBF) autoregulation. We sought to clarify the roles of NO synthase (NOS) isoforms, i.e. neuronal NOS (nNOS) from macula densa, endothelial NOS (eNOS) from the endothelium, and inducible
Hani Hosseinifar et al.
Urology, 82(6), 1291-1295 (2013-10-08)
To study the sperm deoxyribonucleic acid (DNA) fragmentation index (DFI), testicular volume, semen parameters, and hormone profile in human chorionic gonadotropin (hCG)- and human menopausal gonadotrophin (hMG)-treated patients with hypogonadotropic hypogonadism (HH) with and without a successful pregnancy. This is
Oxaliplatin-based chemotherapy in patients aged 75 years or older with metastatic colorectal cancer.
Minoru Fukuchi et al.
Anticancer research, 33(10), 4627-4630 (2013-10-15)
To evaluate the tolerability and efficacy of oxaliplatin-based chemotherapy (OBC) in patients ≥ 75 years old with metastatic colorectal cancer (CRC). We reviewed the medical records of 126 patients with unresectable stage IV CRC in terms of OBC administered as
Joanna Gawinecka et al.
Neuro-degenerative diseases, 9(3), 139-144 (2012-01-04)
The detection of a 14-3-3 elevated level in cerebrospinal fluid (CSF) is a part of the diagnostic criteria for probable sporadic Creutzfeldt-Jakob disease (sCJD), as defined by the WHO. However, some pathological conditions associated with acute neuronal damage may result
Romain Breguet et al.
Cardiovascular and interventional radiology, 42(3), 381-388 (2018-11-10)
To evaluate long-term arterial patency and abnormalities of bile ducts in patients that had endovascular treatment for arterial complications after liver transplantation (LT). Between 2004 and 2014, 1048 LTs were consecutively performed in our institution and 53 patients (42 men;
Thomas S Uldrick et al.
Blood, 124(24), 3544-3552 (2014-10-22)
Kaposi sarcoma (KS) herpesvirus-associated multicentric Castleman disease (KSHV-MCD) is a lymphoproliferative disorder, most commonly seen in HIV-infected patients, that has a high mortality if untreated. Concurrent KS is common. Although rituximab has reported activity in KSHV-MCD, its use is often
Soichi Takizawa et al.
Biochemical and biophysical research communications, 386(1), 192-196 (2009-06-13)
To search autoantigens in autoimmune pancreatitis (AIP), we have screened the human pancreas cDNA library with a patient's serum and obtained 10 positive clones. Seven out of 10 clones were amylase alpha-2A, the autoantibody to which was specifically detected in
Lidia Savi et al.
The journal of headache and pain, 12(6), 609-615 (2011-08-16)
The objectives of this study are to assess the efficacy and safety of frovatriptan, and rizatriptan in the subgroup of women with menstrually related migraine of a multicenter, randomized, double blind, cross-over study. Each patient received frovatriptan 2.5 mg or rizatriptan
Wolfgang Koechling et al.
British journal of clinical pharmacology, 70(4), 580-587 (2010-09-16)
Early studies on gonadotrophin-releasing hormone (GnRH) antagonists pointed out histamine-mediated anaphylactic reactions as a potential adverse effect of these drug candidates. In this study we have compared the histamine-releasing potential of four approved and marketed antagonists, degarelix, cetrorelix, abarelix and
Mohammad Mehrasa et al.
International journal of biological macromolecules, 79, 687-695 (2015-06-06)
Aligned poly lactic-co-glycolic acid (PLGA) and PLGA/gelatin nanofibrous scaffolds embedded with mesoporous silica nanoparticles (MSNPs) were fabricated using electrospinning method. The mean diameters of nanofibers were 641±24 nm for the pure PLGA scaffolds vs 418±85 nm and 267±58 nm for
J L Moyano Calvo et al.
Actas urologicas espanolas, 30(9), 871-878 (2006-12-21)
The natural history of the superficial carcinoma of bladder is characterized by his high rate of recurrence and by the aptitude to progress to higher stages. We are going to investigate the capacity of prediction for tumor recurrence of protein
Robert Howard et al.
The Lancet. Neurology, 14(12), 1171-1181 (2015-10-31)
Findings from observational studies have suggested a delay in nursing home placement with dementia drug treatment, but findings from a previous randomised trial of patients with mild-to-moderate Alzheimer's disease showed no effect. We investigated the effects of continuation or discontinuation
T A Grushko et al.
Gynecologic oncology, 108(1), 3-9 (2007-10-20)
To investigate the frequency and potential prognostic or predictive value of HER-2 amplification or overexpression in advanced and recurrent endometrial cancers. Immunohistochemical staining (IHC; DAKO Herceptest) and fluorescence in situ hybridization (FISH; Vysis Inc. PathVysion DNA Probe Kit) were performed
Lucie Coppin et al.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 16(1), 115-120 (2015-11-29)
CA 19-9 is the gold standard biomarker of pancreatic adenocarcinoma despite several weaknesses in particular a high rate of false positives or negatives. CA-125 corresponding to MUC16 and galectin-3, a lectin able to interact with mucin-associated carbohydrates, are tumor-associated proteins.
Lani K Clinton et al.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 27(6), 1165-1170 (2017-06-13)
The aim of this study was to determine the histopathologic characteristics of patients with endometrial carcinoma with low-volume metastases (micrometastases and isolated tumor cells) compared with macrometastases. We performed a retrospective review of patients with endometrial carcinoma. Among 350 robotic-assisted
Jean-Jacques Wyndaele et al.
Neurourology and urodynamics, 35(2), 252-259 (2015-01-20)
Evaluate the efficacy, safety, and tolerability of a novel pressure-attenuation balloon for the treatment of female stress urinary incontinence (SUI) using a prospective, randomized, single-blind, multi-center design, evaluated at 3 months. Sixty-three females with SUI were randomized 2:1 to treatment
Ai-yuan Zhang et al.
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 25(2), 233-235 (2008-04-09)
To investigate the association of the 4G/5G polymorphism located in the promoter region of plasminogen activator inhibitor-1(PAI-1) gene with prognosis of coronary artery disease (CAD) in Chinese Hans. One hundred and fifty five patients with CAD and 190 unrelated healthy
Olivier Fitoussi et al.
Haematologica, 96(8), 1136-1143 (2011-05-07)
As rituximab combined with CHOP improves complete remission and overall survival in diffuse large B-cell lymphoma, intensified chemotherapy followed by autologous stem-cell transplantation has also been advocated for high-risk patients. The aim of this study was to establish whether or
Koji Tsuta et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 6(7), 1190-1199 (2011-05-31)
Recent clinical trials revealed that accurate histologic typing of non-small cell lung cancer, especially squamous cell carcinoma (SCC), is essential. We analyzed 10 antibodies expression in 150 SCC cases (53 well-, 51 moderately, and 46 poorly differentiated cases) and 159
S Sei et al.
AIDS (London, England), 15(11), 1343-1352 (2001-08-16)
To determine the influences on pediatric AIDS of a heterozygous 32 base pair deletion in the CC-chemokine receptor 5 gene (CCR5 wt/Delta 32) and a common polymorphism in the 3' untranslated region of stromal cell-derived factor-1 beta gene transcript (SDF1-3'A).
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