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SPR Catalysis V26 (2014)
Cong T Trinh
Applied microbiology and biotechnology, 95(4), 1083-1094 (2012-06-09)
Elementary mode (EM) analysis based on the constraint-based metabolic network modeling was applied to elucidate and compare complex fermentative metabolisms of Escherichia coli for obligate anaerobic production of n-butanol and isobutanol. The result shows that the n-butanol fermentative metabolism was
A novel pathway to produce butanol and isobutanol in Saccharomyces cerevisiae
Branduardi P, et al.
Biotechnology for Biofuels, 6(1), 68-68 (2013)
Jacek Sein Anand et al.
Przeglad lekarski, 69(8), 589-591 (2012-12-19)
We presented the male who was addicted to ethanol, and who drank the mixture of different toxic alcohols. Toxicological screening of ingested fluid found 42% vol propan-1-OL, and 17% vol propan-2-OL (isopropanol). After regaining consciousness, the patient stated that substance
Prasenjit Seal et al.
The Journal of chemical physics, 136(3), 034306-034306 (2012-01-28)
The purpose of the present investigation is to calculate partition functions and thermodynamic quantities, viz., entropy, enthalpy, heat capacity, and Gibbs free energies, for 1-butanol, 2-methyl-1-propanol, and butanal in the vapor phase. We employed the multi-structural (MS) anharmonicity method and
Stéphanie Rollero et al.
Applied microbiology and biotechnology, 99(5), 2291-2304 (2014-11-22)
Volatile compounds produced by yeast during fermentation greatly influence the organoleptic qualities of wine. We developed a model to predict the combined effects of initial nitrogen and phytosterol content and fermentation temperature on the production of volatile compounds. We used
Shanshan Li et al.
Biotechnology letters, 34(12), 2253-2258 (2012-09-04)
High-level constitutive gene expression can result in cellular metabolic imbalance and limit production. To circumvent these problems, a P(alsSD)-controlled auto-inducible 2-ketoisovalerate biosynthetic pathway and a P(spac)-controlled IPTG-inducible Ehrlich pathway were constructed in Bacillus subtilis to modulate gene expression. Based on
Xiaoqiang Jia et al.
Applied biochemistry and biotechnology, 168(1), 1-9 (2011-05-04)
Isobutanol can be biosynthesized via α-ketoisovalerate catalyzed by heterologous keto acid decarboxylase (KDC) and alcohol dehydrogenase (ADH). In this work, isobutanol biosynthesis pathway was designed in Bacillus subtilis, a notable solvent-tolerant host. In order to do that, a plasmid pPKA
Sensitive analysis of alkyl alcohols as decomposition products of alkyl nitrites in human whole blood and urine by headspace capillary GC with cryogenic oven trapping
Watanabe-Suzuki K, et al.
Journal of Chromatographic Science, 41(2), 63-66 (2003)
Han Li et al.
Science (New York, N.Y.), 335(6076), 1596-1596 (2012-03-31)
One of the major challenges in using electrical energy is the efficiency in its storage. Current methods, such as chemical batteries, hydraulic pumping, and water splitting, suffer from low energy density or incompatibility with current transportation infrastructure. Here, we report
D Norbäck et al.
Occupational and environmental medicine, 52(6), 388-395 (1995-06-01)
As a part of the worldwide European Community respiratory health survey, possible relations between symptoms of asthma, building characteristics, and indoor concentration of volatile organic compounds (VOCs) in dwellings were studied. The study comprised 88 subjects, aged 20-45 years, from
Cong T Trinh et al.
Applied and environmental microbiology, 77(14), 4894-4904 (2011-06-07)
Fermentation enables the production of reduced metabolites, such as the biofuels ethanol and butanol, from fermentable sugars. This work demonstrates a general approach for designing and constructing a production host that uses a heterologous pathway as an obligately fermentative pathway
Jeremy J Minty et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(36), 14592-14597 (2013-08-21)
Synergistic microbial communities are ubiquitous in nature and exhibit appealing features, such as sophisticated metabolic capabilities and robustness. This has inspired fast-growing interest in engineering synthetic microbial consortia for biotechnology development. However, there are relatively few reports of their use
Jingnan Lu et al.
Applied microbiology and biotechnology, 96(1), 283-297 (2012-08-07)
Wild-type Ralstonia eutropha H16 produces polyhydroxybutyrate (PHB) as an intracellular carbon storage material during nutrient stress in the presence of excess carbon. In this study, the excess carbon was redirected in engineered strains from PHB storage to the production of
Fumio Matsuda et al.
Bioscience, biotechnology, and biochemistry, 76(11), 2139-2141 (2012-11-08)
To increase isobutanol production in Saccharomyces cerevisiae, the valine biosynthetic pathway was activated by overexpression of the relevant enzymes in the mitochondria and the cytosol. Native mitochondrial enzymes were overepxressed in the cytosol by deleting the mitochondrial transit peptides. The
Won-Heong Lee et al.
Bioprocess and biosystems engineering, 35(9), 1467-1475 (2012-05-01)
Engineering of Saccharomyces cerevisiae to produce advanced biofuels such as isobutanol has received much attention because this yeast has a natural capacity to produce higher alcohols. In this study, construction of isobutanol production systems was attempted by overexpression of effective
Luis H Reyes et al.
Applied and environmental microbiology, 79(17), 5313-5320 (2013-07-03)
Cross-tolerance and antagonistic pleiotropy have been observed between different complex phenotypes in microbial systems. These relationships between adaptive landscapes are important for the design of industrially relevant strains, which are generally subjected to multiple stressors. In our previous work, we
Giulia Caron et al.
Journal of medicinal chemistry, 48(9), 3269-3279 (2005-04-29)
Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in
Michael H Abraham et al.
European journal of medicinal chemistry, 43(3), 478-485 (2007-06-05)
Values of in vitro gas to lung partition coefficients, K(lung), of VOCs have been collected from the literature. For 44 VOCs, application of the Abraham solvation equation to log K(lung) yielded a correlation with R(2)=0.968 and S.D.=0.25 log units. Combination
Konstantinos Grintzalis et al.
Applied and environmental microbiology, 80(18), 5561-5571 (2014-07-09)
We show here that oxidative stress is involved in both sclerotial differentiation (SD) and aflatoxin B1 biosynthesis in Aspergillus flavus. Specifically, we observed that (i) oxidative stress regulates SD, as implied by its inhibition by antioxidant modulators of reactive oxygen
Shanshan Li et al.
Microbial cell factories, 11, 101-101 (2012-08-07)
Isobutanol is considered as a leading candidate for the replacement of current fossil fuels, and expected to be produced biotechnologically. Owing to the valuable features, Bacillus subtilis has been engineered as an isobutanol producer, whereas it needs to be further
Isobutanol production from cellobionic acid in Escherichia coli
Desai HS, et al.
Microbial cell factories, 14(1), 52-52 (2015)
R Zernecke et al.
Rhinology, 49(3), 331-336 (2011-08-23)
The detection threshold task of the Sniffin` Sticks can be conducted using two different odorants - n-butanol or phenylethyl alcohol (PEA). Previous studies show contradictory results regarding the correlation analysis of the two odorants. The current study investigated the relationship
N Bilzer et al.
Blutalkohol, 27(6), 385-409 (1990-11-01)
I. In several experiments the kinetics and questionable mutial influences of Methanol, Propanol-1 and Isobutanol were examined while Ethanol was present. II. In five different experiments 30 persons got separate congeners (7 mg Methanol/kg body weight, 5 mg Propanol-1/kg body
Alfonso Pérez-Garrido et al.
Bioorganic & medicinal chemistry, 17(2), 896-904 (2008-12-06)
This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoretical molecular descriptors, calculated solely from the molecular structure of the compounds under investigation
Genny A Pang et al.
The journal of physical chemistry. A, 116(19), 4720-4725 (2012-04-21)
This work presents the first direct experimental study of the rate constant for the reaction of OH with iso-butanol (2-methyl-1-propanol) at temperatures from 907 to 1147 K at near-atmospheric pressures. OH time-histories were measured behind reflected shock waves using a
Dawid Brat et al.
FEMS yeast research, 13(2), 241-244 (2013-01-03)
Simultaneous overexpression of an optimized, cytosolically localized valine biosynthesis pathway together with overexpression of xylose isomerase XylA from Clostridium phytofermentans, transaldolase Tal1 and xylulokinase Xks1 enabled recombinant Saccharomyces cerevisiae cells to complement the valine auxotrophy of ilv2,3,5 triple deletion mutants
Arul M Varman et al.
Applied and environmental microbiology, 79(3), 908-914 (2012-11-28)
Global warming and decreasing fossil fuel reserves have prompted great interest in the synthesis of advanced biofuels from renewable resources. In an effort to address these concerns, we performed metabolic engineering of the cyanobacterium Synechocystis sp. strain PCC 6803 to
László Pál et al.
Immunopharmacology and immunotoxicology, 37(2), 193-201 (2015-02-19)
A large volume of alcoholic beverages containing aliphatic alcohols is consumed worldwide. Previous studies have confirmed the presence of ethanol-induced immunosuppression in heavy drinkers, thereby increasing susceptibility to infectious diseases. However, the aliphatic alcohols contained in alcoholic beverages might also
Jan-Karl Guterl et al.
ChemSusChem, 5(11), 2165-2172 (2012-10-23)
The limited supply of fossil resources demands the development of renewable alternatives to petroleum-based products. Here, biobased higher alcohols such as isobutanol are versatile platform molecules for the synthesis of chemical commodities and fuels. Currently, their fermentation-based production is limited
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