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Virender Singh et al.
Soft matter, 11(26), 5353-5364 (2015-06-11)
Hydrogels of low molecular weight molecules are important in biomedical applications. Multiple factors are responsible for hydrogel formation, but their role in governing self-assembly to hydrogel formation is poorly understood. Herein, we report the hydrogel formation of fluorenylmethyloxycarbonyl phenylalanine (FmocF)
Jinming Zhang et al.
International journal of pharmaceutics, 476(1-2), 185-198 (2014-09-17)
Tanshinone IIA (TAN) has few clinical applications for anti-cancer therapy mainly due to its high lipophicity, low cellular uptake, and poor bioavailability. To improve the anti-cancer effect and bioavailability of TAN, we developed a mixed micelle system constituted with D-α-tocopheryl
Yan Fang et al.
Drug delivery, 23(9), 3582-3593 (2016-09-30)
A kind of polymeric lipid vesicles (PLVs) with pH-responsive turning on-off membrane for programed delivery of insulin in gastrointestinal (GI) tract was developed, which was self-assembled from the grafted amphipathic polymer of N-tocopheryl-N'-succinyl-ɛ-poly-l-lysine (TP/SC-g-PLL). By controlling the grafting ratio of
Kimiko Fukuoka et al.
Biodegradation, 26(5), 359-373 (2015-07-02)
3-Methylindole, also referred to as skatole, is a pollutant of environmental concern due to its persistence, mobility and potential health impacts. Petroleum refining, intensive livestock production and application of biosolids to agricultural lands result in releases of 3-methylindole to the
Chen Tan et al.
Food & function, 6(12), 3702-3711 (2015-09-05)
Interactions between chitosan and the liposomal membrane are relevant to the physiological functionality of chitosan, including dietary fiber, antimicrobial action, and fabrication of a delivery system for bioactives. To elucidate the multiple functions of chitosan, the dependence of liposomal membrane
Pyrene-tagged dendritic catalysts noncovalently grafted onto magnetic Co/C nanoparticles: an efficient and recyclable system for drug synthesis.
Michel Keller et al.
Angewandte Chemie (International ed. in English), 52(13), 3626-3629 (2013-02-22)
Jaleh Varshosaz et al.
Journal of liposome research, 24(3), 191-203 (2013-12-21)
Quercetin (QT) is a potential chemotherapeutic drug with low solubility that seriously limits its clinical use. The aim of this study was enhancing cellular penetration of QT by sterol containing solid lipid nanoparticles (SLNs) which make bilayers fluent for targeting
John C Bachman et al.
Nature communications, 6, 7040-7040 (2015-05-07)
Electrochemical energy-storage devices have the potential to be clean and efficient, but their current cost and performance limit their use in numerous transportation and stationary applications. Many organic molecules are abundant, economical and electrochemically active; if selected correctly and rationally
Matej Bračič et al.
Langmuir : the ACS journal of surfaces and colloids, 31(44), 12043-12053 (2015-10-17)
Mixtures of natural and biodegradable surfactants and ionic polysaccharides have attracted considerable research interest in recent years because they prosper as antimicrobial materials for medical applications. In the present work, interactions between the lysine-derived biocompatible cationic surfactant N(ε)-myristoyl-lysine methyl ester
Qiliang Lai et al.
Journal of bacteriology, 194(24), 6958-6958 (2012-12-05)
Nitratireductor pacificus strain pht-3B(T) was isolated from a pyrene-degrading consortium enriched from the deep sea sediment of the Pacific Ocean. Here, we present the draft genome of strain pht-3B(T), which contains 4,466,205 bp with a G+C content of 65.51% and
Laura Delgado-Moreno et al.
Aquatic toxicology (Amsterdam, Netherlands), 165, 129-135 (2015-06-04)
Natural waters such as surface water and sediment porewater invariably contain dissolved organic matter (DOM). Association of strongly hydrophobic contaminants (HOCs) with DOM leads to decreased toxicity and bioavailability, but bioavailability of DOM-sorbed HOCs is difficult to measure. Current methods
Justin C Lo et al.
Environmental toxicology and chemistry, 34(12), 2782-2790 (2015-06-17)
In vitro bioassays to estimate biotransformation rate constants of contaminants in fish are currently being investigated to improve bioaccumulation assessments of hydrophobic contaminants. The present study investigates the relationship between chemical substrate concentration and in vitro biotransformation rate of 4
I Kira Astakhova et al.
Chemical communications (Cambridge, England), 49(5), 511-513 (2012-12-04)
Novel pyrene-perylene α-L-LNA FRET pairs described herein effectively detect assembly of 2- and 3-way branched DNA nanostructures prepared by postsynthetic microwave-assisted CuAAC click chemistry. The fluorescent signalling of assembly by internally positioned FRET pairs is achieved with low to no
Paula V Messina et al.
Langmuir : the ACS journal of surfaces and colloids, 31(44), 12009-12018 (2015-10-21)
Studies of the self-aggregation of binary systems are of both theoretical and practical importance. They provide an opportunity to investigate the influence of the molecular structure of the hydrophobe on the nonideality of mixing. On the other hand, linear free
Wenpeng Zhang et al.
Journal of chromatography. A, 1365, 19-28 (2014-09-15)
In this work, we interestingly happened to observe the adsorption of stainless steel sample loop of HPLC. The adsorptive behaviors of the stainless steel loop toward different kinds of compounds were studied, including polycyclic aromatic hydrocarbons (PAHs), halogeno benzenes, aniline
Ali Reza Ghiasvand et al.
Analytica chimica acta, 900, 56-66 (2015-11-18)
A simple, low-cost, and effective cooling/heating-assisted headspace solid-phase microextraction (CHA-HS-SPME) device, capable of direct cooling the fiber to low temperatures and simultaneous heating the sample matrix to high temperatures, was fabricated and evaluated. It was able to cool down the
Alicia J Sawdon et al.
Colloids and surfaces. B, Biointerfaces, 122, 738-745 (2014-09-07)
Polymeric prodrug micelles for delivery of acyclovir (ACV) were synthesized. First, ACV was used directly to initiate ring-opening polymerization of ɛ-caprolactone to form ACV-polycaprolactone (ACV-PCL). Through conjugation of hydrophobic ACV-PCL with hydrophilic methoxy poly(ethylene glycol) (MPEG) or chitosan, polymeric micelles
Tracie Perkins Fullove et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 48(3), 233-241 (2012-12-19)
Pyrene, one of the most studied polycyclic aromatic hydrocarbons, can damage biological macromolecules and cause toxicity when irradiated by light. The effect of substituents, 1-amino, 1-hydroxy, 1-nitro, and 1-bromo, on light-induced lipid peroxidation is studied. Degradation kinetics and photoproduct analyses
Keisuke Matsuoka et al.
Journal of oleo science, 64(7), 783-791 (2015-07-03)
The addition of plant sterols/stanols (sterols or stanols) can reduce the solubilization of cholesterol in a model intestinal solution system. We studied the molecular structure of seven different sterols/stanols and the effect they had on the solubilization of cholesterol or
Kyung-mi Choi et al.
Biomaterials, 35(25), 7121-7132 (2014-05-24)
Anticancer therapeutics delivering exogenous siRNA have been explored to suppress the tumor-associated genes, but several limitations of siRNA delivery such as tumor-targeted delivery, controlled siRNA release at the sites of interest, or instabilities of siRNA in physiological fluids should be
Jakub Mondek et al.
Carbohydrate polymers, 129, 168-174 (2015-06-09)
The fast deprotonation of 1-naphthol was studied in aqueous solution and in polymer-cetyltrimethylammonium bromide (CTAB) mixtures using picosecond fluorescence spectroscopy to study the influence of hyaluronan hydration in polymer-surfactant interactions. The aqueous micelle solution showed the expected change of proton
Sudhakar Narra et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 15(14), 2945-2950 (2014-07-22)
Back electron transfer (BET) is one of the important processes that govern the decay of generated ion pairs in intermolecular photoinduced electron transfer reactions. Unfortunately, a detailed mechanism of BET reactions remains largely unknown in spite of their importance for
Megan Mitchell et al.
Biology of reproduction, 80(2), 295-301 (2008-10-31)
The nutrient requirements and metabolic pathways used by the developing embryo transition from predominantly pyruvate during early cleavage stages to glucose at the blastocyst; however, the complexities involved in the regulation of metabolism at different developmental stages are not clear.
Zhaowei Guo et al.
Nature communications, 11(1), 959-959 (2020-02-23)
Hydronium-ion batteries are regarded as one of the most promising energy technologies as next-generation power sources, benefiting from their cost effectivity and sustainability merits. Herein, we propose a hydronium-ion battery which is based on an organic pyrene-4,5,9,10-tetraone anode and an
Li Li et al.
Molecules (Basel, Switzerland), 17(12), 14159-14173 (2012-11-30)
Pyrene derivatives can be carcinogenic, teratogenic and mutagenic, thus having the potential to cause malignant diseases. In this work, the interactions of two selected pyrene derivatives (1-OHP and 1-PBO) and human tumor-related DNA (p53 DNA and C-myc DNA) are investigated
Yi Li et al.
Journal of chromatography. A, 1358, 60-67 (2014-07-20)
A novel TiO2-nanosheets coated fiber for solid-phase microextraction (SPME) was fabricated by anodization of Ti wire substrates in ethylene glycol with concentrated NH4F. The in situ fabricated TiO2-nanosheets were densely embedded into Ti substrates with about 1μm long, 300nm wide
Fuxing Kang et al.
PloS one, 8(3), e58238-e58238 (2013-03-14)
The effects of interactions between genetic materials and polycyclic aromatic hydrocarbons (PAHs) on gene expression in the extracellular environment remain to be elucidated and little information is currently available on the effect of ionic strength on the transformation of plasmid
Shishuai Su et al.
ACS nano, 9(2), 1367-1378 (2015-01-23)
Effective therapeutics against triple negative breast cancer (TNBC), which has no standard-of-care therapy, needs to be developed urgently. Here we demonstrated a strategy of integrating indocyanine green (ICG), paclitaxel (PTX), and survivin siRNA into one thermosensitive poly(2-(2-methoxyethoxy)ethyl methacrylate-co-oligo(ethylene glycol) methacrylate)-co-2-(dimethylamino)ethyl
Sidra Farid et al.
Biosensors & bioelectronics, 71, 294-299 (2015-04-29)
One of the primary goals in the scientific community is the specific detection of proteins for the medical diagnostics and biomedical applications. Interferon-gamma (IFN-γ) is associated with the tuberculosis susceptibility, which is one of the major health problems globally. We
Liliana Martelo et al.
The journal of physical chemistry. B, 119(48), 15023-15029 (2015-11-10)
Phasor plots of the fluorescence intensity decay (plots of the Fourier sine transform versus the Fourier cosine transform, for one or several angular frequencies) are being increasingly used in studies of homogeneous and heterogeneous systems. In this work, the phasor
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