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显示 1-30 共 128 条结果 关于 "83-42-1" 范围 论文
Rantao Zuo et al.
The British journal of nutrition, 110(7), 1220-1232 (2013-03-05)
The effects of conjugated linoleic acid (CLA) on growth performance, non-specific immunity, antioxidant capacity, lipid deposition and related gene expression were investigated in the large yellow croaker (Larmichthys crocea). Fish (7·56 (SEM 0·60) g) were fed soyabean oil-based diets with
Shin-ichiro Kitajiri et al.
Archives of otolaryngology--head & neck surgery, 128(4), 365-367 (2002-04-03)
To assess the efficacy of corticosteroid therapy for sudden-onset sensorineural hearing loss at lower frequencies. Retrospective, nonrandomized, controlled study. The recovery rate, recovery/improvement rate, and period between the start of therapy and improvement of symptoms were studied in 2 groups:
Mengchao Cui et al.
Journal of medicinal chemistry, 54(7), 2225-2240 (2011-03-23)
A new and extensive set of dibenzylideneacetone derivatives was synthesized and screened for affinity toward Aβ(1-42) aggregates. Structure-activity relationships revealed the binding of dibenzylideneacetones to be affected by various substituents. The introduction of a substituent group in the ortho position
Olena Andrukhova et al.
Journal of cardiac failure, 18(3), 253-261 (2012-03-06)
Glutathione S-transferase P1 1 (GSTP1) belongs to the multigene isozyme family involved in cellular response to oxidative stress and apoptosis. Our initial retrospective proteomic analysis suggested that GSTP1 is associated with heart failure (HF). Although pro-B-type natriuretic peptide (proBNP) serves
Mario Tiribelli et al.
Cancer, 117(10), 2156-2162 (2011-04-28)
ABCG2 protein overexpression and FLT3 internal tandem duplication (ITD) correlate with higher relapse rate and shorter disease-free survival (DFS) in acute myeloid leukemia (AML), but no data are available on the possible effect of concomitant presence of these 2 factors.
Manuel Tejada et al.
Ecotoxicology and environmental safety, 74(6), 1708-1714 (2011-05-21)
We studied in the laboratory the effect of Prochloraz fungicide on the biological properties (soil enzymatic activities and soil bacterial communities) of a Plaggic Anthrosol. Five hundred grams of soil (<2mm) was mixed with three dosages of Prochloraz (1, 2
Ben-fu Yang et al.
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 32(6), 454-456 (2009-12-05)
To explore the possible relationship between the -2518 A/G single nucleotide polymorphisms in monocyte chemoattractant protein-1 (MCP-1) gene of Chinese Han population and the susceptibility to pulmonary tuberculosis. A 1:1 matched case-control study was conducted from March 2008 to August
M B Skaddan et al.
Journal of medicinal chemistry, 43(23), 4552-4562 (2000-11-23)
A series of 31 compounds based on the piperidyl or pyrrolidyl benzilate scaffold were prepared from methyl benzilate and 4-piperidinol, (R)-(+)-3-piperidinol, or (R)-(+)-3-pyrrolidinol. Amine substituents included alkyl and aralkyl groups. In vitro K(i) values ranged from 0.05 nM to >100
Inge M W Verberk et al.
Alzheimer's research & therapy, 12(1), 118-118 (2020-09-30)
Blood-based biomarkers for Alzheimer's disease (AD) might facilitate identification of participants for clinical trials targeting amyloid beta (Abeta) accumulation, and aid in AD diagnostics. We examined the potential of plasma markers Abeta(1-42/1-40), glial fibrillary acidic protein (GFAP) and neurofilament light
G Halmos et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(19), 10555-10560 (2000-08-30)
Antagonists of growth hormone-releasing hormone (GHRH) inhibit the proliferation of various human cancers in vitro and in vivo by mechanisms that include apparent direct effects through specific binding sites expressed on tumors and that differ from pituitary human GHRH (hGHRH)
Madeleine Zetterberg et al.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 147B(6), 720-726 (2008-01-01)
Alzheimer's disease (AD) and age-related macular degeneration (AMD) share several epidemiological and biochemical features. The present study aimed to assess the possible influence of the AMD-associated complement factor H (CFH) Y402H (1277T > C) polymorphism on the risk of AD.
Pierre-François Meyer et al.
Journal of Alzheimer's disease : JAD, 63(2), 577-590 (2018-04-18)
Immune mechanisms may be important in the pathogenesis of Alzheimer's disease (AD). Yet, studies comparing cerebrospinal fluid (CSF) and plasma immune marker levels of healthy and demented individuals have yielded conflicting results. We analyzed CSF from 101 members of the
Ayalew Tefferi et al.
Blood, 103(9), 3547-3548 (2004-01-01)
Recent studies have demonstrated neutrophil overexpression of the polycythemia rubra vera-1 (PRV-1) gene in polycythemia vera (PV) but not in secondary or spurious polycythemia (SP). To validate as well as expand upon this novel observation, we conducted a prospective study
B J Gavin et al.
Genes & development, 4(12B), 2319-2332 (1990-12-01)
The mammary tumor-associated proto-oncogene Wnt-1/int-1 encodes a secreted protein implicated in the regulation of neural development in vertebrates and segmental pattern in Drosophila. Using a PCR-based strategy, we isolated cDNAs encoding six novel, related proteins that are expressed in fetal
Marie-Pierre Buisine et al.
World journal of gastroenterology, 14(7), 1053-1059 (2008-02-21)
To investigate the polymorphic simple sequence repeat in intron 1 of the epidermal growth factor receptor gene (EGFR) (CA-SSR I), which is known to affect the efficiency of gene transcription as a putative target of the mismatch repair (MMR) machinery
Bruno Vergès et al.
The Journal of clinical endocrinology and metabolism, 87(2), 457-465 (2002-02-12)
To date, data on pituitary adenomas in MEN type 1 (MEN1) still have to be evaluated. We analyzed the data of a large series of 324 MEN1 patients from a French and Belgian multicenter study. Data on pituitary disease were
Yasufumi Goto et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(11), 3401-3407 (2008-06-04)
Detection of micrometastasis in melanoma-draining lymph nodes is important for staging and prognosis. Immunohistochemical staining (IHC) using S-100p-HMB-45-, and MART-1-specific antibodies is used for detecting metastases in sentinel lymph nodes (SLN). However, improvement in IHC is needed for melanoma micrometastasis
M R Roby et al.
Environmental health perspectives, 69, 215-220 (1986-11-01)
The excretion and tissue distribution of [1-14C]dichloroacetonitrile and [2-14C]dichloroacetonitrile were studied in male Fischer 344 rats and male B6C3F1 mice. Three dose levels of dichloroacetonitrile (DCAN) (0.2, 2, or 15 mg/kg) were administered to rats and two dose levels of
B Chérif-Zahar et al.
Genomics, 19(1), 68-74 (1994-01-01)
The human RH (rhesus) locus is composed of two genes, RHD and RHCE, encoding the D, Cc, and Ee blood group antigens. The RHCE gene was isolated from a human genomic library and characterized. It is organized into 10 exons
K Sofue et al.
The British journal of surgery, 101(9), 1122-1128 (2014-06-13)
This study aimed to evaluate the safety and efficacy of preoperative right portal vein embolization (PVE) with absolute ethanol in patients with hepatobiliary malignancies. PVE was performed via a percutaneous transhepatic ipsilateral approach, and the right portal branch was embolized
Tetsuzo Nakayama et al.
Biochemical pharmacology, 68(1), 23-32 (2004-06-09)
Proteolysis plays an important role in inactivating protease-activated receptor-1 (PAR1). We aimed to determine the cleavage site(s) responsive for the proteolytic inactivation of PAR1 in human umbilical vein endothelial cells. Fura-2 fluorometry revealed that the preceding stimulation with trypsin abolished
D Gunnersen et al.
Proceedings of the National Academy of Sciences of the United States of America, 89(24), 11949-11953 (1992-12-15)
In this report, 8- and 2-azidoadenosine 5'-[gamma-32P]triphosphate were used to examine cerebrospinal fluid (CSF) samples for the presence of an ATP binding protein unique to individuals with Alzheimer disease (AD). A 42-kDa ATP binding protein was found in the CSF
S Ellard et al.
Clinical endocrinology, 62(2), 169-175 (2005-01-27)
Diagnostic molecular genetic testing for multiple endocrine neoplasia type 1 (MEN1) has been available since the identification of the MEN1 gene in 1997. Mutation screening of the MEN1 gene has been recommended for patients who meet clinical criteria for MEN1
Z Radovanovic et al.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 30(9), 913-917 (2004-10-23)
Sentinel lymph node biopsy in breast cancer can be used to select patients in which axillary lymph node dissection could be avoided. In this study we compared the value of two methods for identification of sentinel node (SN) using either
Siew-Kim Khoo et al.
The Journal of allergy and clinical immunology, 113(3), 475-481 (2004-03-10)
The IL12B gene encodes the p40 chain of IL-12, a proinflammatory cytokine that antagonizes TH2 expression and hence may play a critical role in the pathogenesis of airway inflammation observed in asthma. A promoter polymorphism of the gene was recently
José M Porcel et al.
Chest, 147(2), 513-519 (2014-09-26)
Chest CT scanning has become an integral part of the workup for undiagnosed pleural effusions. We aimed to develop a CT scan-based scoring system for differentiating between benign and malignant pleural effusions. A number of chest CT scan abnormalities were
Brian K White et al.
Diagnostic microbiology and infectious disease, 84(2), 144-150 (2015-11-27)
Data from recent conflicts related to war wounds and obligate anaerobes are limited. We define the epidemiology and antimicrobial susceptibility of obligate anaerobes from Iraq and Afghanistan casualties (6/2009-12/2013), as well as their association with clinical outcomes. Susceptibility against eleven
A F Hahn et al.
Brain : a journal of neurology, 113 ( Pt 5), 1511-1525 (1990-10-01)
Modern techniques have defined the hereditary motor and sensory neuropathies (HMSN) as a genetically heterogeneous group of disorders. This includes a rare variant with X-linked dominant inheritance. We have traced this disorder through 6 generations of a large Canadian kindred;
Ronald M Adkins et al.
BMC pregnancy and childbirth, 5(1), 2-2 (2005-02-05)
BACKGROUND: Fetal growth restriction is associated with significantly increased risks of neonatal death and morbidity and with susceptibility to hypertension, cardiovascular disease and NIDDM later in life. Human birth weight has a substantial genetic component, with at least a quarter
Murat Akyildiz et al.
European journal of gastroenterology & hepatology, 22(2), 192-198 (2009-10-16)
To investigate the macrophage migration inhibitory factor (MIF) expression and -173 G/C polymorphism of the MIF gene in nonalcoholic fatty liver disease (NAFLD). Ninety-one patients with diagnosis of NAFLD and 104 healthy controls were included in the study. MIF -173
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