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Laurence M M Crombag et al.
The European respiratory journal, 53(2) (2018-12-24)
Guidelines recommend endosonography for mediastinal nodal staging in patients with resectable nonsmall cell lung cancer (NSCLC). We hypothesise that a systematic endobronchial ultrasound (EBUS) evaluation combined with an oesophageal investigation using the same EBUS bronchoscope (EUS-B) improves mediastinal nodal staging
Linda Helbig et al.
International journal of radiation oncology, biology, physics, 88(1), 159-166 (2013-12-18)
To study the effects of BAY-84-7296, a novel orally bioavailable inhibitor of mitochondrial complex I and hypoxia-inducible factor 1 (HIF-1) activity, on hypoxia, microenvironment, and radiation response of tumors. UT-SCC-5 and UT-SCC-14 human squamous cell carcinomas were transplanted subcutaneously in nude
Ping-Yen Liu et al.
Atherosclerosis, 195(1), 199-206 (2006-11-28)
Cytochrome P450 (CYP) 2J2 is expressed in vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs), which are potent endogenous vasodilators and inhibitors of vascular inflammation. We aimed to elucidate the relationship between the functional CYP2J2*7 polymorphism
Bridget E Barber et al.
Journal of clinical microbiology, 51(4), 1118-1123 (2013-01-25)
Plasmodium knowlesi can cause severe and fatal human malaria in Southeast Asia. Rapid diagnosis of all Plasmodium species is essential for initiation of effective treatment. Rapid diagnostic tests (RDTs) are sensitive for detection of uncomplicated and severe falciparum malaria but
Telma Gadelha et al.
Cerebrovascular diseases (Basel, Switzerland), 19(1), 49-52 (2004-11-06)
This study investigates the association between cerebral vein thrombosis (CVT) and the mutations FV 1691A (factor V Leiden), PT 20210A and MTHFR 677TT and acquired factors including oral contraceptive (OC) use. 26 patients (21 females) and 217 healthy controls (134
Ulla Wilking et al.
Breast cancer research and treatment, 125(2), 553-561 (2010-07-16)
This retrospective study investigates the correlation of intra-individual HER2 status between primary breast cancers and corresponding recurrences in a population derived cohort. The REMARK criteria were used as reference. In 151 breast cancer patients, primary tumors were analyzed for HER2
Luana Paula Haubold Neis Veiga et al.
Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria, 21(2), 133-136 (2012-07-27)
With the objective of evaluating Rhipicephalus (Boophilus) microplus resistance to cipermetrina and amitraz, were collected engorged tick females from cattle on 20 farms on the Santa Catarina Plateau, in southern Brazil, between January of 2004 and May of 2006. Were
Oluwole Fadare et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 30(3), 252-261 (2011-04-06)
Earlier reports have indicated that patients with endometrial clear cell carcinoma (CCC) may have an increased risk for thromboembolic events. Tissue factor is a 47-Kd transmembrane glycoprotein that plays a critical role in platelet activation, fibrinogenesis, blood clot formation, and
Yan-Rong Jiang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(19), 3271-3276 (2014-01-16)
Porous silica was used as a carrier to prepare tanshinone solid dispersions (SDs). sThe effect of the spray drying method or the solvent method on the drug dissolution of SD was studied. The structure characteristics of SDs was analyzed by
Azin Shafieesabet et al.
Parkinsonism & related disorders, 42, 1-11 (2017-06-26)
Studies have suggested that the majority of patients with Parkinson's disease have abnormal ultrasound hyperechogenicity of the substantia nigra, and that this may be useful in diagnosis. We performed a systematic review and meta-analysis to evaluate diagnostic value of substantia
R P Moody et al.
Journal of toxicology and environmental health, 20(1-2), 209-218 (1987-01-01)
The dermal penetration of 14C-ring-labeled fenitrothion and aminocarb was determined in rats and rhesus monkeys. In monkeys, 49 +/- 4% (t1/2 = 14 h) of the fenitrothion and 74 +/- 4% (t1/2 = 25 h) of aminocarb were absorbed from
Q-J Wang et al.
Clinical genetics, 72(3), 245-254 (2007-08-28)
There is a worldwide interest in studying SLC26A4 mutations that are responsible for enlarged vestibular aqueduct (EVA) in different ethnic background and populations. The spectrum of SLC26A4 mutations in Chinese population is yet to be fully characterized. In this study
Marinez Farana Matos et al.
Metabolic syndrome and related disorders, 11(1), 29-34 (2012-10-03)
Abdominal obesity increases the risk of venous thromboembolism (VTE). It remains unclear to what extent inflammation contributes to the risk of VTE from abdominal obesity. Our objectives were to investigate the association between abdominal obesity and VTE and the effect
A-M Orbai et al.
Lupus, 24(1), 42-49 (2014-08-16)
Anti-C1q has been associated with systemic lupus erythematosus (SLE) and lupus nephritis in previous studies. We studied anti-C1q specificity for SLE (vs rheumatic disease controls) and the association with SLE manifestations in an international multicenter study. Information and blood samples
Anu Suomalainen et al.
The Lancet. Neurology, 10(9), 806-818 (2011-08-09)
Muscle biopsy is the gold standard for diagnosis of mitochondrial disorders because of the lack of sensitive biomarkers in serum. Fibroblast growth factor 21 (FGF-21) is a growth factor with regulatory roles in lipid metabolism and the starvation response, and
X H Chen et al.
Journal of chromatography, 617(1), 147-151 (1993-07-23)
The lot-to-lot reproducibilities of Bond Elut Certify and Clean Screen DAU columns are described. The recoveries of five test drugs obtained from twelve lots of Bond Elut Certify columns ranged from 84 to 104% with standard deviations of less than
R K Reinecke et al.
The Onderstepoort journal of veterinary research, 48(4), 235-238 (1981-12-01)
A group of 12 10-month-old, worm-free Merino lambs were given a single injection of disophenol at 10 mg/kg. This group and another group of 12 worm-free lambs were infested with infective larvae of Haemonchus contortus 1-3 times a week with
Karen Yanson et al.
Journal of clinical microbiology, 59(12), e0101921-e0101921 (2021-09-30)
Nucleic acid amplification testing (NAAT) for SARS-CoV-2 is the standard approach for confirming COVID-19 cases. This study compared results between two emergency use authorization (EUA) NAATs, with two additional EUA NAATs utilized for discrepant testing. The limits of detection (LOD)
G R Linke et al.
Endoscopy, 44(7), 684-689 (2012-04-25)
Animal data and limited clinical evidence suggest a low incidence of infection following transvaginal natural orifice transluminal endoscopic surgery (NOTES). However, a systematic microbiological evaluation has not yet been carried out. The aim of this prospective cohort study was to
Øistein R Mjelva et al.
European journal of preventive cardiology, 23(11), 1130-1140 (2015-12-05)
Vascular inflammation plays a key role in the development of atherosclerosis and acute coronary syndrome (ACS), and pentraxin 3 (PTX3) is one of several novel, promising markers of inflammation. In addition, D-dimer might serve as a marker of thrombogenesis and
Anders Björkman et al.
Clinical orthopaedics and related research, (425), 168-172 (2004-08-05)
The purpose of the current study was to determine whether factor V Leiden and the prothrombin 20210A gene mutation are risk factors for osteonecrosis of the femoral head in different etiologic groups of osteonecrosis in adults and whether patients with
Tommy Øhlenschlaeger et al.
The New England journal of medicine, 351(3), 260-267 (2004-07-16)
Cardiovascular disease is an important complication in patients with systemic lupus erythematosus (SLE). Variant alleles of the mannose-binding lectin gene are associated with SLE as well as with severe atherosclerosis. We determined whether mannose-binding lectin variant alleles were associated with
F Lussana et al.
Journal of thrombosis and haemostasis : JTH, 13(1), 136-141 (2014-11-13)
Although experimental studies have demonstrated that platelets are proinflammatory cells, no randomized studies have tested the anti-inflammatory effect of antiplatelet agents in humans. The platelet P2Y12 receptors mediated bronchial inflammation in a mouse model of asthma, suggesting that P2Y12 represents
Mathula Thangarajh et al.
British journal of haematology, 159(3), 352-359 (2012-09-11)
Silent cerebral infarct (SCI) is the most commonly recognized cause of neurological injury in sickle cell anaemia (SCA). We tested the hypothesis that magnetic resonance angiography (MRA)-defined vasculopathy is associated with SCI. Furthermore, we examined genetic variations in glucose-6-phosphate dehydrogenase
David Berendes et al.
PloS one, 14(11), e0225464-e0225464 (2019-11-23)
Because poor sanitation is hypothesized as a major direct and indirect pathway of exposure to antimicrobial resistance genes (ARGs), we sought to determine a) the prevalence of and b) environmental risk factors for gut carriage of key ARGs in a
M H Lyda et al.
Human pathology, 31(8), 980-987 (2000-09-15)
The histologic classification of pulmonary neoplasms can have important implications regarding appropriate management of patients. Although the histologic classification of lung tumors is predominantly based on morphology, ancillary studies such as immunohistochemistry can be used in difficult cases, and the
T Groten et al.
Archives of gynecology and obstetrics, 289(3), 581-593 (2013-09-10)
The aim of this study was to evaluate possible associations of genetic polymorphisms predisposing to cardiovascular disease with the development and/or the severity of preeclampsia. A two hospital-based prospective case-control study was performed in Germany and Ghana. 470 blood samples
Terhi Tapiainen et al.
JAMA pediatrics, 168(7), 635-641 (2014-05-07)
Antimicrobial treatment reduces the symptoms of acute otitis media (AOM). The effect of antimicrobial treatment on the duration of middle ear effusion (MEE) and concomitant hearing impairment is not known. To determine whether the antimicrobial treatment of AOM reduces the
Nicolas F Schlecht et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(10), 1295-1305 (2011-05-17)
Detection of human papillomavirus (HPV) in head and neck cancer has therapeutic implications. In situ hybridization and immunohistochemistry for p16 are used by surgical pathologists. We compared the sensitivity and specificity of three popular commercial tests for HPV detection in
Mingxin Zhang et al.
The Journal of urology, 194(3), 647-652 (2015-04-29)
Neutrophil gelatinase associated lipocalin, also known as lipocalin-2, is a 25 kDa protein now considered the biochemical gold standard for the early diagnosis of acute kidney injury. Recently lipocalin-2 was suggested to have an important role in several human neoplasias.
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