85-00-7

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Effects of sunlight and diet on vitamin D status of pulmonary tuberculosis patients in Tbilisi, Georgia.

Nirali S Desai et al.

Nutrition (Burbank, Los Angeles County, Calif.), 28(4), 362-366 (2012-02-07)

Vitamin D deficiency is common in tuberculosis (TB) and this may modulate immune responses. This study investigated vitamin D status in patients with TB and examined the sources of vitamin D in Tbilisi, Georgia. We measured plasma 25-hydroxyvitamin D (25[OH]D)

In vivo and in vitro evaluation of the estrogenic properties of the 17β-(butylamino)-1,3,5(10)-estratrien-3-ol (buame) related to 17β-estradiol.

Cristina Lemini et al.

Pharmacological reports : PR, 64(4), 940-950 (2012-10-23)

Buame [17β-(butylamino)-1,3,5(10)-estratrien-3-ol] possesses anticoagulant and antiplatelet activities that are potentially antithrombotic. Since its estrogenicity is unknown, it was evaluated by established methods. Buame (10, 100, 500, and 1,000 μg/kg), 17β-estradiol (E(2)) (100 μg/kg), or propylene glycol (10 ml/kg) were subcutaneously

Comparison of acellular pertussis-tetanus-diphtheria vaccines and whole-cell pertussis-tetanus-diphtheria vaccines in infancy.

Huseyin Anil Korkmaz et al.

Paediatrics and international child health, 34(3), 198-202 (2014-03-14)

In clinical trials, diphtheria, tetanus and acellular pertussis vaccines have been shown to be less reactogenic than whole-cell combination vaccines. To evaluate diphtheria and tetanus toxoids combined with acellular pertussis (DTaP) and diphtheria and tetanus toxoids combined with whole-cell pertussis

Docetaxel and prednisone with or without lenalidomide in chemotherapy-naive patients with metastatic castration-resistant prostate cancer (MAINSAIL): a randomised, double-blind, placebo-controlled phase 3 trial.

Daniel P Petrylak et al.

The Lancet. Oncology, 16(4), 417-425 (2015-03-07)

Patients with metastatic castration-resistant prostate cancer have few treatment options. We investigated the safety and efficacy of lenalidomide, an immunomodulatory agent with anti-angiogenic properties, in combination with docetaxel and prednisone in chemotherapy-naive patients with metastatic castration-resistant prostate cancer. In this

Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials.

N Bhala et al.

Lancet (London, England), 382(9894), 769-779 (2013-06-04)

The vascular and gastrointestinal effects of non-steroidal anti-inflammatory drugs (NSAIDs), including selective COX-2 inhibitors (coxibs) and traditional non-steroidal anti-inflammatory drugs (tNSAIDs), are not well characterised, particularly in patients at increased risk of vascular disease. We aimed to provide such information

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