850408P

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Extraction and profiling of plant polar glycerol lipids

Liu Y and Wang X

Bio-protocol, 6(10), 1849e-1849e null

Mechanically Enhancing Planar Lipid Bilayers with a Minimal Actin Cortex.

Daniel L Burden et al.

Langmuir : the ACS journal of surfaces and colloids, 34(37), 10847-10855 (2018-08-29)

All cells in all domains of life possess a cytoskeleton that provides mechanical resistance to deformation and general stability to the plasma membrane. Here, we utilize a two-dimensional scaffolding created by actin filaments to convey mechanical support upon relatively fragile

Peptide-Mediated Membrane Transport of Macromolecular Cargo Driven by Membrane Asymmetry.

Xin Li et al.

Analytical chemistry, 89(22), 12369-12374 (2017-10-21)

Pep-1 is a cell-penetrating peptide that represents a powerful strategy for delivering large, hydrophilic therapeutic molecules into cells. Model membranes, such as lipid vesicles and planar bilayers, have been useful for investigating the direct translocation of cell-penetrating peptides. Here, we

The distribution and function of phosphatidylserine in cellular membranes.

Peter A Leventis et al.

Annual review of biophysics, 39, 407-427 (2010-03-03)

Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

A critical reassessment of penetratin translocation across lipid membranes.

Elsa Bárány-Wallje et al.

Biophysical journal, 89(4), 2513-2521 (2005-07-26)

Penetratin is a short, basic cell-penetrating peptide able to induce cellular uptake of a vast variety of large, hydrophilic cargos. We have reassessed the highly controversial issue of direct permeation of the strongly cationic peptide across negatively charged lipid membranes.

A Comparative Study of Phosphatidylcholine versus Phosphatidylserine-Based Solid Supported Membranes for the Preparation of Liposome-Rich Interfaces.

Alessio Sacconi et al.

Langmuir : the ACS journal of surfaces and colloids, 34(40), 12183-12190 (2018-09-16)

Solid supported membranes (SSMs) are usually formed by an hybrid octadecanethiol/phosphatidylcholine (PC) bilayer supported by a gold electrode. Recently, it was shown that phosphatidylserine (PS) in place of PC can promote a more effective accumulation of lipid vesicles on the

Interactions between ether phospholipids and cholesterol as determined by scattering and molecular dynamics simulations.

Jianjun Pan et al.

The journal of physical chemistry. B, 116(51), 14829-14838 (2012-12-04)

Cholesterol and ether lipids are ubiquitous in mammalian cell membranes, and their interactions are crucial in ether lipid mediated cholesterol trafficking. We report on cholesterol's molecular interactions with ether lipids as determined using a combination of small-angle neutron and X-ray

Diphytanoyl lipids as model systems for studying membrane-active peptides.

Sezgin Kara et al.

Biochimica et biophysica acta. Biomembranes, 1859(10), 1828-1837 (2017-06-08)

The branched chains in diphytanoyl lipids provide membranes with unique properties, such as high chemical/physical stability, low water permeability, and no gel-to-fluid phase transition at ambient temperature. Synthetic diphytanoyl phospholipids are often used as model membranes for electrophysiological experiments. To

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