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F Ducray et al.
Neurology, 72(2), 156-161 (2009-01-14)
alpha-Internexin (INA) is a proneural gene encoding a neurofilament interacting protein that is upregulated in some gliomas, particularly oligodendrogliomas. INA expression was evaluated by immunohistochemistry in a series of 122 gliomas, and correlated to the 1p19q codeletion, a favorable prognostic
J-E Eom et al.
Vox sanguinis, 107(2), 181-187 (2014-02-13)
Transplantation of cryopreserved umbilical cord blood (UCB) can be used to treat a multitude of haematologic and immunological diseases. In this study, we examined the quality of UCB cryopreserved for 2 (group I), 4 (group II) and 6 (group III)
Július Árvay et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 50(11), 833-843 (2015-09-12)
The contamination level of 92 samples (12 species) of wild edible mushrooms and underlying substrates with heavy metals (Cd, Cu, Hg, Pb and Zn) in the Slovak Paradise National Park that borders with a region of historical mining and processing
Hiroyuki Ukeda et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 18(10), 1151-1154 (2002-10-29)
A novel highly water-soluble tetrazolium salt, WST-1 (4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene disulfonate sodium salt), can be reduced to water-soluble formazan with a superoxide anion. Here, the WST-1 assay was applied to detect the superoxide anion generated during the Maillard reaction. A sample solution
Matthias Christian Kugler et al.
Gene, 341, 189-197 (2004-10-12)
Ras-related C3 toxin substrate 1 (Rac1) is a small Rho-GTPase with important functions in fundamental cellular processes such as cytoskeleton rearrangements, signal transduction, cell cycle progression and malignant transformation. Using Rac1 primer, we identified a 5.5-kb DNA sequence on chromosome
Michael Sippach et al.
Biochimica et biophysica acta, 1838(7), 1760-1768 (2014-03-04)
The conformational dynamics of the histidine ABC transporter HisQMP2 from Salmonella enterica serovar Typhimurium, reconstituted into liposomes, is studied by site-directed spin labeling and double electron-electron resonance spectroscopy in the absence of nucleotides, in the ATP-bound, and in the post-hydrolysis
Wendy Pollock et al.
Journal of immunological methods, 347(1-2), 19-23 (2009-06-06)
Most laboratories screen for antineutrophil cytoplasmic antibodies (ANCA) with indirect immunofluorescence (IIF) and confirm cytoplasmic (C-ANCA) and perinuclear (P-ANCA) staining with ELISAs for proteinase 3 (PR3) and myeloperoxidase (MPO) specificities. This study determined the concordance of ANCA test results from
Sina Gallo et al.
The Journal of nutrition, 143(2), 148-153 (2012-12-21)
The biological equivalency of ergocalciferol (D2) and cholecalciferol (D3) has been debated; several comparisons have appeared in the adult literature but are scarce in pediatrics. The objective of this study was to compare increases in plasma 25-hydroxyvitamin D [25(OH)D] concentrations
Naoko Ishiguro et al.
Human pathology, 39(11), 1673-1679 (2008-07-29)
Cardiac ankyrin repeat protein (CARP) is highly expressed in cardiac muscles and detectable in normal skeletal muscles. Arpp, a close homolog of CARP, has been demonstrated to be useful for distinguishing rhabdomyosarcoma from other malignant tumors. However, the CARP distributions
C R Jones et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 10(1), 10-28 (2005-08-16)
Nitrotoluenes are important intermediates in the chemical industry. 2,6-Dinitrotoluene (26DNT), 2,4-dinitrotoluene (24DNT) and 2-nitrotoluene (2NT) are carcinogenic in animals and possibly carcinogenic in humans. Thus, it is important to develop methods to biomonitor workers exposed to such chemicals. The authors
Abbas Güngördü
Aquatic toxicology (Amsterdam, Netherlands), 140-141, 220-228 (2013-07-09)
The assessments of pesticide toxicity on nontarget organisms have largely been focused on the determination of median lethal concentration (LC50) values using single/laboratory species. Although useful, these studies cannot describe the biochemical mechanisms of toxicity and also cannot explain the
César Ricardo Teixeira Tarley et al.
Food chemistry, 334, 127345-127345 (2020-07-28)
The development of a novel molecularly imprinted solid-phase extraction (MISPE) method for simultaneous preconcentration of imazapyr (IMP), imazapic (IMZ) and imazethapyr (IMT) with determination by HPLC-PAD (High performance liquid chromatography - photodiode-array detector) is proposed. The polymer synthesis was performed
Tatsuaki Tagami et al.
Journal of controlled release : official journal of the Controlled Release Society, 152(2), 303-309 (2011-02-23)
We have developed a novel and simplified thermosensitive liposomal formulation (HaT: Hyperthermia-activated cytoToxic) composed of DPPC lipid and Brij78 (96:4, molar ratio). The HaT nanoparticles were loaded with doxorubicin (DOX) with >95% efficiency when a pH gradient method and a
Y C Yen et al.
The Kaohsiung journal of medical sciences, 17(4), 190-197 (2001-08-03)
We aimed to determine the association and related factors of the apolipoprotein E (ApoE) genotype and Alzheimer's disease (AD) in Taiwan. We examined ApoE genotypes in 50 Chinese patients with AD and 50 age- and sex-matched controls. The patients met
Karl Sörelius et al.
Circulation, 130(24), 2136-2142 (2014-11-08)
Mycotic aortic aneurysm (MAA) is a rare and life-threatening disease. The aim of this European multicenter collaboration was to study the durability of endovascular aortic repair (EVAR) of MAA, by assessing late infection-related complications and long-term survival. All EVAR treated
Erika M Whitney et al.
Gene expression, 13(2), 85-96 (2006-10-05)
Krüppel-like factor 4 (KLF4; also known as gut-enriched Krüppel-like factor or GKLF) is known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle. The mechanism by which KLF4 exerts these effects is not fully established.
Kentaro Nakayama et al.
Cancer biology & therapy, 5(6), 630-634 (2006-04-22)
Analysis of deleted chromosomal regions in tumors has historically led to the identification of tumor suppressor genes. In this study, we used digital karyotyping, a genome-wide, high-resolution technology, to search for chromosomal deletions in ovarian serous carcinoma, the most lethal
Heimo H Wenzl et al.
Digestive diseases and sciences, 60(5), 1414-1423 (2014-11-09)
Many patients with quiescent Crohn's disease are maintained on long-term treatment with azathioprine (AZA), but controlled data are limited. We aimed to evaluate the efficacy of AZA therapy for more than 4 years to maintain clinical remission. We performed a
Y Tomigahara et al.
Xenobiotica; the fate of foreign compounds in biological systems, 25(11), 1195-1206 (1995-11-01)
1. To examine the metabolic fate of Cyanox [O-4-cyanophenyl O, O-dimethyl phosphorothioate, cyanophos, CYAP], rats of both sexes were administered [phenyl-4C]Cyanox as a single oral dose at levels of 0.5 mg/kg (low-dose group) or 25 mg/kg (high-dose group), or as
D Barillà et al.
International angiology : a journal of the International Union of Angiology, 33(5), 466-473 (2014-10-09)
The aim of this study was to compare the results of complex aneurysm (hostile neck anatomies) repair in high-risk patients with two minimally invasive techniques, fenestrated endografting (f-EVAR where EVAR stands for endovascular aneurysm repair) and minilaparotomy. All high-risk patients
Anders Boyd et al.
Hepatology (Baltimore, Md.), 60(2), 497-507 (2014-04-23)
Tenofovir (TDF) is considered the ideal treatment for patients coinfected with human immunodeficiency virus (HIV) and hepatitis B virus (HBV). However, certain coinfected patients exhibit incomplete viral suppression, with persistent, and sometimes transient, bouts of HBV replication. The reasons for
Fatemeh Tohidi et al.
Environmental science and pollution research international, 22(15), 11387-11400 (2015-03-27)
A gas chromatography/mass spectrometry (GC/MS)-based method was developed for simultaneous determination of triclosan (TCS) and its degradation products including 2,4-dichlorophenol (2,4-DCP), 2,8-dichlorodibenzo-p-dioxin (2,8-DCDD), and methyl triclosan (MTCS) in wastewater and sludge samples. The method provides satisfactory detection limit, accuracy, precision
J M Tiercy et al.
Bone marrow transplantation, 26(4), 437-441 (2000-09-12)
Patients transplanted with marrow from an HLA-ABDR serologically matched unrelated donor suffer from more post-transplant complications than those who are transplanted with marrow from an HLA-identical sibling. This is most likely due to either HLA-ABDR incompatibilities not resolved by standard
J M Lord et al.
Diabetologia, 25(2), 108-113 (1983-08-01)
The effect of metformin on hepatocyte insulin receptor binding was examined in normal, streptozotocin diabetic and genetically obese diabetic (ob/ob) mice. In normal mice, chronic administration of metformin (60 mg X kg-1 X day-1 for 50 weeks) increased the number
Ben Davidson et al.
Virchows Archiv : an international journal of pathology, 477(6), 857-864 (2020-06-14)
The objective of this study was to analyze the expression and clinical role of mitosis regulators α-thalassemia/mental retardation syndrome X-linked (ATRX) and death-domain-associated protein (DAXX) in metastatic high-grade serous carcinoma (HGSC). ATRX and DAXX protein expression by immunohistochemistry was analyzed
Agnieszka Permoda-Osip et al.
Neuropsychobiology, 69(2), 107-111 (2014-03-01)
Increased levels of homocysteine have been observed in various psychiatric disorders, among them in schizophrenia, depression and bipolar mood disorder. Of the genes connected with homocysteine metabolism, some studies have found an association between polymorphism of the methylenetetrahydrofolate reductase (MTHFR)
Monika Sparber-Sauer et al.
Pediatric blood & cancer, 65(12), e27405-e27405 (2018-08-21)
Patients with metastatic alveolar soft-part sarcoma (ASPS) are known to have a very poor prognosis. Little is known about best treatment of primary metastatic disease (MD) or relapsed metastatic disease (rMD). Patients with localized disease (LD), primary MD, and metastatic
Margo E Godersky et al.
Journal of addiction medicine, 14(4), 319-325 (2020-01-24)
Video directly observed therapy (video-DOT) through a mobile health platform may improve buprenorphine adherence and decrease diversion. This pilot study tested the acceptability and feasibility of using this technology among patients receiving buprenorphine in an office-based setting. Participants were instructed
Molebogeng X Rangaka et al.
Lancet (London, England), 384(9944), 682-690 (2014-05-20)
Antiretroviral therapy reduces the risk of tuberculosis, but tuberculosis is more common in people with HIV than in people without HIV. We aimed to assess the effect of isoniazid preventive therapy on the risk of tuberculosis in people infected with
Renate B Schnabel et al.
Lancet (London, England), 386(9989), 154-162 (2015-05-12)
Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years. We investigated trends in incidence, prevalence, and risk factors for atrial fibrillation
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