Mannitol (Pearlitol
50C, Roquette, Lestrem) as hydrophilic filler. Different
grades of PVA (4-88, 18-88, 40-88, MilliporeSigma,
Germany) were used as binder, 5% w/w was added
to the filler. Additionally
25%
PVA 18–88 ✓ ✓ 18%
PVA 26–88 ✓ ✓ 15%
PVA 40–88 ✓ ✓ 13%
PVA 28–99 ✓ ✓ 15%
* Maximum solubility was defined as the concentration at which the mixture exceeded
).
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