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E T Lyons et al.
American journal of veterinary research, 42(6), 1043-1045 (1981-06-01)
Critical tests were conducted in 14 naturally infected equids (13 horses and 1 pony) to evaluate the antiparasitic activity of haloxon. Single doses were administered by stomach tube to 3 horses and 1 pony (60 mg/kg of body weight), by
Z Kote-Jarai et al.
British journal of cancer, 105(8), 1230-1234 (2011-09-29)
A family history of prostate cancer (PrCa) is a strong risk factor for the disease, indicating that inherited factors are important in this disease. We previously estimated that about 2% of PrCa cases diagnosed ≤ 55 years harbour a BRCA2
Lodovico Balducci et al.
American journal of clinical oncology, 37(6), 603-610 (2014-10-29)
To evaluate primary prophylaxis with pegfilgrastim, a recombinant human granulocyte colony-stimulating factor, on maintaining relative dose intensity (RDI) in patients with non-Hodgkin lymphoma (NHL) receiving cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or CHOP-rituximab (CHOP-R). This retrospective analysis pooled data from
M Forsgren et al.
FEBS letters, 213(2), 254-260 (1987-03-23)
A human liver cDNA library enriched for full-length clones was screened for plasminogen cDNA using a synthetic 24-nucleotide probe derived from a reported partial cDNA sequence. 12 positive clones were identified and one of these was characterized in detail. The
Miranda G Dik et al.
Neurobiology of aging, 24(4), 573-581 (2003-04-26)
Insulin-like growth factor I (IGF-I) deficiency may be involved in cognitive deficits seen with aging, and in neurodegenerative diseases such as Alzheimer's disease. The objective of this study was to investigate whether IGF-I is associated with cognitive performance and 3-year
K Kuwasako et al.
The Journal of biological chemistry, 276(52), 49459-49465 (2001-10-10)
When co-expressed with a receptor activity-modifying protein (RAMP) accessory protein, calcitonin receptor-like receptor (CRLR) can function as a calcitonin gene-related peptide receptor (CRLR-RAMP1) or an adrenomedullin (AM) receptor (CRLR-RAMP2/3). Here we report on the structural domain(s) involved in selective AM
Jia-Chi Wang et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 13(8), 2354-2361 (2007-04-05)
Cluster-of-differentiation antigen 9 (CD9) protein, a member of the tetraspanin family, has been implicated in carcinogenesis of various human tumors. Although decreased expression of the CD82 tetraspanin protein, a close CD9 relative, is associated with prostate cancer progression, CD9 expression
H Sylvin et al.
Immunogenetics, 51(1), 59-64 (2000-02-09)
Interleukin-5 (IL-5) is thought to be a key cytokine in allergic inflammation. Pig IL-5 was cloned, sequenced, and expressed to enable us to study of the biological role of IL-5 in pigs used in a model for allergen-induced late-phase reactions.
C D Howell et al.
Journal of immunology (Baltimore, Md. : 1950), 155(5), 2350-2358 (1995-09-01)
Murine graft-vs-host disease (GVHD) results in destruction of small bile ducts in the liver. We analyzed the TCR V beta repertoire of lymphocytes isolated from the livers and spleens of individual B10.D2 into irradiated BALB/c GVHD mice by means of
Victoria L Blair et al.
Inorganic chemistry, 48(18), 8863-8870 (2009-09-15)
Alkali-metal-mediated manganation (AMMMn) reactions of the synergic base sodium monoalkyl-bisamidomanganate [(tmeda)Na(tmp)(CH(2)SiMe(3))Mn(tmp)] (1) with naphthalene, 1-methoxynaphthalene, or 2-methoxynaphthalene are reported. These novel direct manganation [Mn(II)] reactions produced the crystalline ortho-manganated naphthyl products [(tmeda)Na(tmp)(2-C(10)H(7))Mn(tmp)] (3), [(tmeda)Na(tmp){2-(1-MeOC(10)H(6))}Mn(CH(2)SiMe(3))] (4), and [(tmeda)Na(tmp){3-(2-MeOC(10)H(6))}Mn(tmp)] (5) in reasonable
Anirban Maitra et al.
American journal of clinical pathology, 118(1), 52-59 (2002-07-12)
We extended the results of a previous microarray analysis by immunohistochemical validation of differential protein expression in a series of 57 surgically resected infiltrating ductal pancreatic adenocarcinomas. Two representative genes were examined: sea urchin fascin homolog (overexpressed in both cell
S Karason et al.
Acta anaesthesiologica Scandinavica, 57(5), 639-645 (2013-02-26)
Bladder catheterisation may be inconvenient for patients, delay mobilisation and risk complications. We hypothesised that by excluding pre-operatively patients at high risk of post-operative urinary retention, the majority of patients could avoid perioperative catheterisation during low-dose spinal anaesthesia. Patients undergoing
Haruhiko Machida et al.
Japanese journal of radiology, 33(2), 84-93 (2014-12-17)
We retrospectively investigated the effect of the motion correction algorithm (MCA) on image quality and interpretability by heart rate (HR) in coronary CT angiography (CCTA). For 105 patients (6 HR groups) undergoing CCTA, 2 readers independently graded the image quality
G J Wang et al.
Molecular pharmacology, 53(1), 88-96 (1998-01-28)
We assayed glutamate transport activity in cultures of rat cortical neurons containing < 0.2% astrocytes. Using [3H]L-glutamate as the tracer, sodium-dependent high affinity glutamate transport was demonstrated [K(m) = 17.2 +/- 2.4 microM; Vmax = 3.3 +/- 0.32 nmol/mg of
A Houde et al.
Molecular reproduction and development, 39(2), 127-135 (1994-10-01)
We report the complementary DNA structure obtained by reverse transcription and polymerase chain reaction amplification encoding the complete amino acid sequence for the bovine follicle-stimulating hormone receptor (bFSHr). The deduced amino acid sequence for the cDNA revealed a mature polypeptide
Nady El Hajj et al.
Diabetes, 62(4), 1320-1328 (2012-12-05)
Epigenetic processes are primary candidates when searching for mechanisms that can stably modulate gene expression and metabolic pathways according to early life conditions. To test the effects of gestational diabetes mellitus (GDM) on the epigenome of the next generation, cord
D G Romero et al.
The Journal of steroid biochemistry and molecular biology, 72(5), 231-237 (2000-05-24)
The bovine 11beta-hydroxysteroid dehydrogenase type 2 enzyme (11beta-HSD-2) cDNA was cloned from three overlapping PCR fragments using primers based on the human and ovine 11beta-HSD-2 cDNA sequences. Both cDNA ends were obtained by a modified RACE (Rapid Amplification of cDNA
M Attanasio et al.
Clinical genetics, 74(1), 39-46 (2008-04-26)
Fibrillin-1 gene (FBN1) mutations cause Marfan syndrome (MFS), an inherited connective tissue disorder with autosomal dominant transmission. Major clinical manifestations affect cardiovascular and skeletal apparatuses and ocular and central nervous systems. We analyzed FBN1 gene in 99 patients referred to
D L Rainwater et al.
Heredity, 102(2), 147-154 (2008-10-31)
Paraoxonase-1 (PON1) is associated with high-density lipoprotein (HDL) particles and is believed to contribute to antiatherogenic properties of HDLs. We assessed the determinants of PON1 activity variation using different substrates of the enzyme. PON1 activity in serum samples from 922
Daniel Ge Thiem et al.
The International journal of oral & maxillofacial implants, 34(1), 133–140-133–140 (2018-10-04)
This study aimed to evaluate whether different surface modifications affect the dynamics of bone remodeling at the implant and the adjacent local bone. Seventy-two dental implants with different surfaces (smooth and rough control [smCtrl; rCtrl], smooth and rough + O2-plasma
E D N S Abeyrathne et al.
Poultry science, 93(4), 1010-1017 (2014-04-08)
Ovotransferrin and ovomucoid were separated using 2 methods after extracting the ovotransferrin- and ovomucoid-containing fraction from egg white. Diluted egg white (2×) was added to Fe(3+) and treated with 43% ethanol (final concentration). After centrifugation, the supernatant was collected and
Joanna Reszeć et al.
Medical science monitor : international medical journal of experimental and clinical research, 17(8), BR216-BR220 (2011-08-02)
Astrocytic tumors are the primary brain tumors, which often progress to glioblastoma, a highly malignant neoplasm of the central nervous system. There is much new data regarding to the formation and progression of these tumors; however, glioblastoma remains one of
Upendra Joshi et al.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 34(3), 299-307 (2013-12-03)
We aimed to evaluate clinical outcomes and identify the predictors of mortality in elderly patients undergoing continuous ambulatory peritoneal dialysis (CAPD). This retrospective cohort study included all incident CAPD patients treated at our center from 2006 to 2009. Demographic and
E G Miller et al.
Journal of animal science, 95(6), 2701-2710 (2017-07-21)
Parity-2 ( = 39) and -3 ( = 28; same sows from parity-2 sows) Yorkshire sows were used to measure whole body protein deposition (Pd) during gestation (maternal and pregnancy-associated) at 2 feeding levels to test the hypothesis that the
Beatriz Grinsztejn et al.
The lancet. HIV, 6(9), e588-e600 (2019-08-03)
Antiretroviral therapy (ART) management is challenging for individuals in resource-limited settings presenting for third-line treatment because of complex resistance patterns, partly due to reduced access to viral load monitoring. We aimed to evaluate use of newer antiretroviral drugs and contemporary
Motowo Yamaguchi et al.
Inorganic chemistry, 45(20), 8342-8354 (2006-09-27)
New ruthenium(II) complexes having a tetradentate ligand such as tris(2-pyridylmethyl)amine (TPA), tris[2-(5-methoxycarbonyl)pyridylmethyl]amine [5-(MeOCO)3-TPA], tris(2-quinolylmethyl)amine (TQA), or bis(2-pyridylmethyl)glycinate (BPG) have been prepared. The reaction of the ligand with [RuCl2(Me2SO)4] resulted in a mixture of trans and cis isomers of the chloro(dimethyl
Nevin C Baker et al.
Journal of interventional cardiology, 29(1), 108-112 (2016-01-06)
We evaluate the prevalence of complications and failure rates between the most commonly used "active" anchoring vascular closure device (VCD), AngioSeal™ and the "passive" anchoring VCD, Mynx™, in all-comers undergoing percutaneous coronary intervention (PCI). A total of 4,074 patients between
J C MacPherson et al.
Journal of immunology (Baltimore, Md. : 1950), 166(9), 5763-5772 (2001-04-21)
Eosinophil recruitment and enhanced production of NO are characteristic features of asthma. However, neither the ability of eosinophils to generate NO-derived oxidants nor their role in nitration of targets during asthma is established. Using gas chromatography-mass spectrometry we demonstrate a
Roza Badr Eslam et al.
Thrombosis research, 129(4), 453-458 (2011-08-06)
Calcific aortic valve stenosis is linked to atherosclerosis. The latter is associated with increased levels of platelets adhering to monocytes (PMA). The hemodynamic impairment in symptomatic aortic valve stenosis can be abated by valve replacement. We investigated the effect of
T L Peeters et al.
Naunyn-Schmiedeberg's archives of pharmacology, 343(2), 202-208 (1991-02-01)
Recent studies suggested that certain erythromycin A (EM-A) derivatives are motilin receptor agonists. As proposed by Itoh they may be called "motilides". We have investigated the Ca2(+)-dependence of contractions induced by two potent motilides, ME-34 [de(N-methyl) 8,9-anhydroeryhtromycin A 6,9-hemiacetal] and
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