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Ralph Carvalho et al.
Genes, chromosomes & cancer, 45(10), 967-975 (2006-07-27)
Diffuse-type gastric carcinomas (GCs) are often difficult to characterize because of contamination of tumor samples by surrounding normal tissue. As such, information regarding chromosomal aberrations in this subtype of GCs is limited. In this study, we used representational difference analysis
K S Barron et al.
Arthritis and rheumatism, 38(5), 684-689 (1995-05-01)
Although HLA-B27 is strongly associated with susceptibility to Reiter's syndrome (RS), recent data suggest that an additional modifying or susceptibility gene(s) acts in concert with HLA-B27 to contribute to disease pathogenesis. The recently described TAP genes (transporters associated with antigen
C D Petraki et al.
Prostate cancer and prostatic diseases, 6(3), 223-227 (2003-09-13)
Human kallikreins 6, 10 and 13 (hK6, hK10 and hK13) are expressed by many normal, mainly glandular tissues, including prostatic epithelium. Some kallikreins may function as tumor suppressors or are downregulated during cancer progression. The aim of this study was
Ilario Fulco et al.
Lancet (London, England), 384(9940), 337-346 (2014-04-15)
Autologous native cartilage from the nasal septum, ear, or rib is the standard material for surgical reconstruction of the nasal alar lobule after two-layer excision of non-melanoma skin cancer. We assessed whether engineered autologous cartilage grafts allow safe and functional
P Knöbl et al.
Thrombosis and haemostasis, 71(6), 692-697 (1994-06-01)
Diabetes mellitus is associated with disturbances of the hemostatic system, which might contribute to the development of diabetic vascular disease. We investigated the effect of metabolic improvement by insulin therapy on the haemostatic system in 61 patients with type 2
Zhengxiu Su et al.
PloS one, 9(6), e100331-e100331 (2014-06-20)
Heart damage is widely present in patients with chronic kidney disease. Salt diet is the most important environmental factor affecting development of chronic renal failure and cardiovascular diseases. The proteins involved in chronic kidney disease -induced heart damage, especially their
Ankita Bhattacharjee et al.
Pharmaceutical biology, 54(3), 433-444 (2015-05-15)
Nicotine is an abundant and most significant component of cigarette smoke. Epidemiological evidence strongly suggests an association between cigarette smoking and pancreatic injury, although effects of smoking on endocrine pancreas are still controversial. We examined the impact and underlying mechanisms
Benjamin Brokinkel et al.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 21(12), 2077-2082 (2014-07-30)
During treatment of large vestibular schwannomas, incomplete resection (IR) followed by Gamma Knife surgery (GKS; Elekta AB, Stockholm, Sweden) possibly offers tumor growth control and good clinical outcome, and is being discussed as an alternative to complete tumor removal with
R C Niessen et al.
Gut, 55(12), 1781-1788 (2006-04-26)
Patients with early-onset colorectal cancer (CRC) or those with multiple tumours associated with hereditary non-polyposis colorectal cancer (HNPCC) raise suspicion of the presence of germline DNA mismatch repair (MMR) gene mutations. To analyse the value of family history, microsatellite instability
J Emmerechts et al.
Thrombosis research, 129(4), 514-519 (2011-07-23)
Partial inhibition of Factor VIII (FVIII) may provide antithrombotic efficacy whilst avoiding excessive anticoagulation. We studied the anticoagulant effects of a partial (TB-402) and a complete (BO2C11) FVIII-inhibiting monoclonal antibody (MAb) on FVIII, aPTT, thrombin generation and fibrin deposition in
Peter Lim et al.
Gastrointestinal endoscopy, 81(4), 932-942 (2014-12-17)
Cholangioscopy is used to diagnose and treat various biliary lesions. Balloon-assisted cholangioscopy (BAC) has mostly been reported in Asian patients with large bile ducts. To assess the feasibility and accuracy of performing BAC in complex biliary diseases in Australian patients.
Suganya Kannan et al.
International journal of biological macromolecules, 141, 218-231 (2019-09-04)
In this study, L-methioninase (METs) was precipitated from Pseudomonas putida MTCC 9782 and was cross-linked with a cross-linking agent glutaraldehyde to obtain a catalytically active insoluble enzyme. Among the various precipitants tested, ammonium sulfate displayed the highest precipitating (80%) efficiency.
Andrea C Lo et al.
International journal of radiation oncology, biology, physics, 88(5), 1011-1018 (2014-03-26)
We report long-term outcomes and complications of craniopharyngioma patients referred to our institution. Between 1971 and 2010, 123 consecutive patients received primary treatment for craniopharyngioma in British Columbia and were referred to our institution. The median age was 30 years
Kai Ming Chow et al.
Renal failure, 28(1), 15-20 (2006-03-11)
Vascular endothelial growth factor (VEGF) plays a pivotal role in the capillary endothelial cell growth and proliferation and has known effects on glomerular microvascular permeability. Because certain VEGF polymorphisms are correlated with alterations in VEGF expression, we hypothesized that VEGF
Fred A Weaver et al.
Journal of vascular surgery, 47(6), 1266-1273 (2008-04-29)
Recombinant thrombin (rThrombin) is a potential hemostatic alternative to bovine and human plasma-derived thrombin. This report examines the clinical results for the vascular surgery subgroup of patients enrolled in a larger double-blind, randomized, multicenter trial, which evaluated the comparative safety
Edward B Garon et al.
Lancet (London, England), 384(9944), 665-673 (2014-06-17)
Ramucirumab is a human IgG1 monoclonal antibody that targets the extracellular domain of VEGFR-2. We aimed to assess efficacy and safety of treatment with docetaxel plus ramucirumab or placebo as second-line treatment for patients with stage IV non-small-cell-lung cancer (NSCLC)
Maria A Figueredo et al.
The Journal of rheumatology, 33(10), 1980-1986 (2006-10-03)
To investigate the prevalence of anti-C-reactive protein (CRP) autoantibodies in patients with systemic lupus erythematosus (SLE) and non-SLE patients with persistent antiphospholipid antibodies (aPL) and their association with clinical manifestations. Sera of 137 patients with SLE, 127 with persistent aPL
Peiguo G Chu et al.
The American journal of surgical pathology, 26(8), 978-988 (2002-08-10)
Hepatocyte monoclonal antibody (Hep) (alternatively Hep Par 1 for Hep paraffin 1) has been reported to stain normal hepatic tissue and hepatocellular carcinoma (HCC) with high specificity. We have studied the Hepatocyte expression in 96 cases of HCC and 311
J Maylie et al.
The Journal of physiology, 442, 551-567 (1991-10-01)
1. The effects of 2,3-butanedione monoxime (BDM) on the optical retardation and myoplasmic Ca2+ signal were studied in twitch fibres of Rana temporaria. The myoplasmic Ca2+ transient in response to action potential stimulation was monitored in cut fibres containing Antipyrylazo
Sally N Adebamowo et al.
International journal of stroke : official journal of the International Stroke Society, 10(7), 1093-1100 (2015-06-06)
Intakes of magnesium, potassium, and calcium have been inversely associated with the incidence of hypertension, a known risk factor for stroke. However, only a few studies have examined intakes of these cations in relation to risk of stroke. The aim
Scott W Powers et al.
JAMA, 310(24), 2622-2630 (2013-12-26)
Early, safe, effective, and durable evidence-based interventions for children and adolescents with chronic migraine do not exist. To determine the benefits of cognitive behavioral therapy (CBT) when combined with amitriptyline vs headache education plus amitriptyline. A randomized clinical trial of
Gian Luca Di Tanna et al.
The Lancet. Global health, 7(2), e191-e199 (2019-01-27)
Xpert MTB/RIF, the most widely used automated nucleic acid amplification test for tuberculosis, is available in more than 130 countries. Although diagnostic accuracy is well documented, anticipated improvements in patient outcomes have not been clearly identified. We performed an individual
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