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显示 1-30 共 1680 条结果 关于 "90-30-2" 范围 论文
Susan Goldhaber et al.
Inhalation toxicology, 21 Suppl 3, 17-55 (2009-10-16)
Application of Provisional Advisory Level (PAL) protocols was performed for acrylonitrile, as experimental data permitted. Three levels (PAL 1, PAL 2, and PAL 3), distinguished by severity of toxic effects, are developed for 24-hour, 30-day, 90-day, and 2-year durations of
Bettina K Windisch et al.
Clinical & experimental ophthalmology, 37(3), 299-307 (2009-05-29)
We wanted to investigate whether heat shock protein (HSP) 27 and HSP 72 are induced in retinal ganglion cells (RGCs) after acute intraocular pressure (IOP)-induced ischaemia. Retinal ischaemia was induced by acutely increasing IOP to 100-110 mmHg for 30 or
Matthew J Watt et al.
The Journal of physiology, 547(Pt 1), 301-308 (2003-02-04)
It has been proposed that hormone-sensitive lipase (HSL) regulates intramuscular triacylglycerol hydrolysis in skeletal muscle. The primary purpose of this study was to examine the early activation of HSL and the changes in the putative intramuscular and hormonal regulators of
Christine M Pauken et al.
Acta biomaterialia, 7(11), 3973-3980 (2011-08-02)
Rational design of biomaterials requires understanding how cells interrogate their microenvironment. In this study, human umbilical vein endothelial cells are cultured on combinations of extracellular matrix (ECM) components (collagen I, collagen IV, vitronectin, fibronectin, laminin, heparan sulfate proteoglycan, chondroitin sulfate
Ke Zhang et al.
Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control, 23(6), 695-696 (2012-03-03)
To evaluate the snail control effect of a film covering method in fish ponds and ditches. Two fish ponds and 2 ditches with Oncomelania snails were selected as pilots, and 1 fish pond as Group A1 and I ditch as
J G Wilcox et al.
Fertility and sterility, 66(5), 748-752 (1996-11-01)
To determine the independent biologic effects of 17 alpha-dihydroequilin sulfate. Prospective randomized study. University of Southern California Medical Center. Twenty-one postmenopausal women, mean age 50 +/- 2 (+/-SEM) years, and mean body mass index 27 +/- 2. Women were randomized
Vivian Glück et al.
Infection, 49(4), 739-746 (2021-03-11)
To follow serological immune responses of front-line healthcare workers after PCR-confirmed COVID-19 for a mean of 30 weeks, describe the time-course of SARS-CoV-2 spike protein-specific IgG, IgA and IgM levels and to identify associations of the immune response with symptoms, demographic
J Koudy Williams et al.
Journal of cardiovascular translational research, 8(7), 411-420 (2015-09-06)
CD133mAb conjugation (CD133-C) hastens in vivo recellularization of decellularized porcine heart valve scaffolds when placed in the pulmonary position of sheep. We now characterize this early cellularization process 4 h, 3, 7, 14, 30, or 90 days post-implantation. Quantitative immunohistochemistry
Figen Atalay et al.
The Kaohsiung journal of medical sciences, 28(2), 72-78 (2012-02-09)
Acute lung injury is an inflammatory syndrome that increases the permeability of the blood-gas barrier, resulting in high morbidity and mortality. Despite intensive research, treatment options remain limited. We investigated the protective efficacy of tezosentan, a novel, dual endothelin receptor
Dana Glass et al.
Inhalation toxicology, 21 Suppl 3, 73-94 (2009-10-16)
The Provisional Advisory Level (PAL) protocol was applied to estimate inhalation exposure limits for phosgene (CG). Three levels (PAL 1, PAL 2, and PAL 3), distinguished by severity of toxic effects, are developed for 24-hour, 30-day, 90-day, and 2-year durations
Hongmin Zhang et al.
Experimental eye research, 110, 107-112 (2013-03-26)
Fungal keratitis is a common disease that causes blindness. An effective animal model for fungal keratitis is essential for advancing research on this disease. Our objective is to develop a novel mouse model of Fusarium solani keratitis through the inoculation
David L Wyles et al.
Hepatology (Baltimore, Md.), 60(1), 56-64 (2014-02-07)
This phase II trial assessed the efficacy and safety of a combination regimen of the nonstructural protein (NS)5A inhibitor ledipasvir (LDV), NS3 protease inhibitor vedroprevir (VDV), non-nucleoside NS5B inhibitor tegobuvir (TGV), and ribavirin (RBV) in treatment-naïve patients with chronic hepatitis
Artur H Swiergiel et al.
The Journal of pharmacology and experimental therapeutics, 302(3), 1031-1036 (2002-08-17)
Interleukin-1 (IL-1) induces hypophagia, which can be reduced by cyclooxygenase (COX) inhibitors. Earlier studies with COX knockout (COXko) mice suggested that COX2 was more important for hypophagia than COX1. However, behavioral responses occur long before COX2 is induced. Hypophagia was
Gang Luo et al.
World neurosurgery, 109, e318-e328 (2017-10-11)
Early recanalization of acute posterior circulation stroke caused by large intracranial vessel occlusion by mechanical thrombectomy with stent retrievers may improve the outcome of patients. However, evidence of patient selection is still lacking. This study investigated the prognostic factors of
M Greenwald et al.
Current medical research and opinion, 27(10), 2033-2042 (2011-09-13)
To further assess the clinically active dose range of etoricoxib, a COX-2 selective inhibitor, in rheumatoid arthritis (RA). RA patients were randomized to etoricoxib 10, 30, 60, or 90 mg or placebo in a double-blind, 12-week study. DMARDs (methotrexate, biologics) or
Andrea Henze et al.
Diabetes, 57(12), 3323-3326 (2008-09-18)
It has been suggested that retinol-binding protein 4 (RBP4) links adiposity, insulin resistance, and type 2 diabetes. However, circulating RBP4 levels are also affected by kidney function. Therefore, the aim of this study was to test whether RBP4 serum levels
Nariman Nezami et al.
Clinical biochemistry, 43(16-17), 1294-1299 (2010-08-24)
Osteoprotegerin (OPG), a glycoprotein, is a member of the tumor necrotizing factor alpha receptor super-family. By considering the possible role of OPG in cardiovascular disease (CVD), higher incidence of CVD in people with type 2 diabetic nephropathy (T2DN), and anti-atherosclerotic
Rama Sivasubramanian et al.
International journal of clinical pharmacology and therapeutics, 53(7), 550-556 (2015-05-07)
To compare the pharmacokinetics (PKs) of a combination oral contraceptive (OC) when given alone or concomitantly with the selective metabotropic glutamate receptor 5 antagonist mavoglurant (AFQ056). This open-label, fixed-sequence, two-period study included 30 healthy female subjects aged 18-40 years. In
Christopher Brooks Mobley et al.
Journal of the International Society of Sports Nutrition, 12, 14-14 (2015-03-21)
We examined the acute effects of different dietary protein sources (0.19 g, dissolved in 1 ml of water) on skeletal muscle, adipose tissue and hypothalamic satiety-related markers in fasted, male Wistar rats (~250 g). Oral gavage treatments included: a) whey protein concentrate (WPC
Davy Guillarme et al.
Journal of chromatography. A, 1216(15), 3232-3243 (2009-03-03)
The UHPLC strategy which combines sub-2 microm porous particles and ultra-high pressure (>1000 bar) was investigated considering very high resolution criteria in both isocratic and gradient modes, with mobile phase temperatures between 30 and 90 degrees C. In isocratic mode
Guru Sonpavde et al.
Urologic oncology, 30(5), 607-613 (2010-10-05)
The association of a change in serum alkaline phosphatase (ALP) with overall survival OS in men with metastatic castration-resistant prostate cancer (CRPC) receiving chemotherapy is unknown. We evaluated the association of changes in ALP within 90 days with OS in
Jorgelina Manes et al.
Theriogenology, 85(5), 856-861 (2015-12-03)
The use of intravaginal sponges (IS) to synchronize estrous onset in ewes provokes vaginitis, an increase in the vaginal bacterial load, and growth of bacterial species that are not present during spontaneous estrous behavior. The objective of the study was
Martin Pšenička et al.
Theriogenology, 83(6), 1085-1092 (2015-01-07)
We report, for the first time, a series of baseline techniques comprising isolation and transplantation of female and male early-stage germ cells in sturgeon to generate a germline chimera as a potential tool for surrogate reproduction and gene banking. Cells
R M Khashaba et al.
International endodontic journal, 44(4), 342-352 (2011-01-29)
To evaluate the histopathologic biocompatibility of two new calcium phosphate-based sealers (CPS-1 & CPS-2) with a commercially available calcium hydroxide-based sealer (Acroseal). Polyethylene tubes were filled with freshly mixed sealers and implanted subcutaneously in the dorsal connective tissue of rats.
Layne E Norton et al.
The Journal of nutrition, 139(6), 1103-1109 (2009-05-01)
This study examined the impact of leucine (Leu) derived from complete meals on stimulation of skeletal muscle protein synthesis (MPS). Expt. 1 examined time course changes in translation initiation and MPS after a meal. Male rats ( approximately 300 g)
Xiu-Qin Wang et al.
Clinical and experimental pharmacology & physiology, 35(10), 1215-1221 (2008-06-04)
The G(q)-protein is located at the convergent point in the signal transduction pathway that leads to ventricular remodelling. In G-protein signalling pathways, the carboxyl terminus of the G(alpha)-subunit plays a vital role in G-protein-receptor interaction. The aim of the present
Hui Sun et al.
The Journal of general physiology, 132(1), 101-113 (2008-07-02)
Two types of voltage-dependent Ca(2+) channels have been identified in heart: high (I(CaL)) and low (I(CaT)) voltage-activated Ca(2+) channels. In guinea pig ventricular myocytes, low voltage-activated inward current consists of I(CaT) and a tetrodotoxin (TTX)-sensitive I(Ca) component (I(Ca(TTX))). In this
Maryam Goudarzi et al.
Journal of proteome research, 14(9), 4039-4049 (2015-08-12)
Despite considerable research into the environmental risks and biological effects of exposure to external beam γ rays, incorporation of radionuclides has largely been understudied. This dosimetry and exposure risk assessment is challenging for first responders in the field during a
Richard A Preston et al.
Antimicrobial agents and chemotherapy, 63(10) (2019-07-25)
WCK 4282 is a combination product of cefepime (FEP) and tazobactam (TAZ) in a 1:1 ratio currently under development for the treatment of multidrug-resistant Gram-negative bacterial infections. We investigated the effect of renal impairment on the pharmacokinetics (PK) and safety
Jonas T Treebak et al.
American journal of physiology. Endocrinology and metabolism, 292(3), E715-E722 (2006-11-02)
We investigated time- and intensity-dependent effects of exercise on phosphorylation of Akt substrate of 160 kDa (AS160) in human skeletal muscle. Subjects performed cycle exercise for 90 min (67% VO2 peak, n=8), 20 min (80% VO2 peak, n=11), 2 min
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