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Manish M Khandagale et al.
Journal of chromatography. A, 1356, 180-187 (2014-07-09)
The solvent dependency of the detection response is a major limitation of corona-charged aerosol detection (C-CAD). The present study empirically investigates the utility of temperature and flow-rate gradients to overcome solvent gradient limitations of C-CAD. In preliminary flow-injection investigations, it
Kun Qian et al.
Journal of economic entomology, 106(2), 979-987 (2013-06-22)
A commercial vinegar product (ChinKiang) was found to be highly attractive to adult house flies, Musca domestica L. Field experiments on a Nebraska dairy demonstrated that traps baited with vinegar and brown sugar captured more house flies than those baited
Hasan Imam et al.
Pakistan journal of biological sciences : PJBS, 16(23), 1796-1800 (2014-02-11)
Previously it was reported elsewhere that Lawsonia inermis have anti-inflammatory and analgesic effect in experimental animals. The in vitro porcine alpha amylase inhibitory effect was investigated of this plant methanolic extracts and consequently hypoglycemic effect by quantitatively determining the maltose
Sabrina Haag et al.
Journal of immunology (Baltimore, Md. : 1950), 194(6), 2539-2550 (2015-02-13)
Rheumatoid arthritis (RA) is associated with amino acid variants in multiple MHC molecules. The association to MHC class II (MHC-II) has been studied in several animal models of RA. In most cases these models depend on T cells restricted to
Yellela S R Krishnaiah et al.
International journal of pharmaceutics, 475(1-2), 110-122 (2014-08-05)
The effect of process variability on physicochemical characteristics and in vitro performance of qualitatively (Q1) and quantitatively (Q2) equivalent generic acyclovir topical dermatological creams was investigated to develop a matrix of standards for determining their in vitro bioequivalence with reference
Yuzo Yamada et al.
International journal of food microbiology, 125(1), 15-24 (2008-01-18)
Taxonomic studies of acetic acid bacteria were historically surveyed. The genus Acetobacter was first introduced in 1898 with a single species, Acetobacter aceti. The genus Gluconobacter was proposed in 1935 for strains with intense oxidation of glucose to gluconic acid
Jincui Huang et al.
Journal of proteome research, 14(3), 1335-1349 (2015-01-30)
Secretory immunoglobulin A (sIgA) is a major glycoprotein in milk and plays a key role in mediating immune protection of the gut mucosa. Although it is a highly glycosylated protein, its site-specific glycosylation and associated glycan micro-heterogeneity have still not
Kalpana Mandal et al.
Nature communications, 5, 5749-5749 (2014-12-11)
Cells sense and respond to their mechanical environment by exerting forces on their surroundings. The way forces are modulated by extra-cellular matrix (ECM) properties plays a key role in tissue homoeostasis. Using highly resolved micropatterns that constrain cells into the
Sevgi Turker et al.
Biochimica et biophysica acta, 1838(12), 3088-3096 (2014-09-10)
Epilepsy is characterized by disruption of balance between cerebral excitation and inhibition, leading to recurrent and unprovoked convulsions. Studies are still underway to understand mechanisms lying epileptic seizures with the aim of improving treatment strategies. In this context, the research
Abdulselam Ertas et al.
Pharmaceutical biology, 53(3), 334-339 (2014-10-22)
In Turkey, Veronica species (Plantaginaceae) have been used as a diuretic and for wound healing in traditional medicine. To examine the fatty acid and essential oil profiles, the antioxidant, anticholinesterase, antimicrobial, and DNA damage effects of Veronica thymoides P.H. Davis
Lynne Gaffikin et al.
Obstetrical & gynecological survey, 58(8), 543-550 (2003-07-30)
Developing countries often lack the necessary resources to use the Papanicolaou (Pap) smear as a screening tool for cervical abnormalities. Because the burden of cervical cancer is highest in such low-resource settings, alternative techniques have been sought. Recently, interest in
Yang Shu et al.
Journal of chromatography. A, 1390, 50-61 (2015-03-17)
Three cyclofructan-based, two glycopeptide-based, and one zwitterionic column used in the HILIC mode were assessed within a graphical framework based on different functional characteristics contributing to selectivity. The characteristics of these six HILIC columns are put in the perspective of
Xing-Yu Xu et al.
Fitoterapia, 101, 218-223 (2015-01-27)
Two new sesquiterpene lactone dimers, neojaponicone B (1) and inulanolide E (2) along with five known sesquiterpene lactone dimers (3-7, resp.) were isolated from the aerial parts of Inula japonica Thunb. The chemical structures of 1 and 2 were elucidated
Zhaozhou Li et al.
Journal of pharmaceutical and biomedical analysis, 98, 210-220 (2014-06-20)
The molecularly imprinted polymers (MIPs) were prepared by an oxidation-reduction polymerization system using a non-covalent molecularly imprinting strategy with hypericin as the template, acrylamide as the functional monomer and pentaerythritol triacrylate as the cross-linker in the porogen of acetone. The
Yifeng Xue et al.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 12(3), 253-260 (2014-06-09)
To evaluate the immunomodulatory properties of human amniotic mesenchymal stromal cells. Human amniotic mesenchymal stromal cells were isolated, characterized by flow cytometry, cultured in vitro, and evaluated in allogeneic and xenogeneic mixed lymphocyte reactions. The proliferation of T cells and
Gemma Buron-Moles et al.
Journal of proteomics, 114, 136-151 (2014-12-03)
Apples are subjected to both abiotic and biotic stresses during the postharvest period, which lead to large economic losses worldwide. To obtain biochemical insights into apple defense response, we monitored the protein abundance changes (proteome), as well as the protein
Tie Yi Kiew et al.
International journal of pharmaceutics, 484(1-2), 115-123 (2015-03-01)
While the supersaturation generation capability of amorphous nanopharmaceuticals (NPs) in their aqueous suspension form has been well established, their supersaturation generation is adversely affected after drying. Herein we investigated the effects of freeze drying on the supersaturation generation capability of
Hayrettin O Gülcan et al.
Archiv der Pharmazie, 348(1), 55-61 (2015-01-13)
The current structure-activity relationship of profens (i.e., 2-arylpropionic acid derivatives, a class of non-steroidal anti-inflammatory drugs) discusses the importance of α-monomethyl substitution on these compounds, since the activities obtained through their corresponding arylacetic acid derivatives (i.e., α-demethylated derivatives) or α,α-dimethyl-substituted
Imène Chaïr-Yousfi et al.
International immunopharmacology, 25(1), 19-29 (2015-01-21)
Lung injury and respiratory distress syndrome are frequent symptoms observed in the most severe cases of scorpion envenomation. The uncontrolled transmigration of leukocyte cells into the lung interstitium and alveolar space and pulmonary edema may be the cause of death.
Jessica Karlsson et al.
PloS one, 9(7), e103589-e103589 (2014-07-26)
In addition to their effects upon prostaglandin synthesis, the non-steroidal anti-inflammatory drugs ibuprofen and flurbiprofen inhibit the metabolism of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA) by cyclooxygenase-2 (COX-2) and fatty acid amide hydrolase (FAAH), respectively. Here, we investigated whether
J F A Valente et al.
Analytical biochemistry, 459, 61-69 (2014-05-28)
The p53 tumor suppressor gene has been widely explored for gene therapy as an alternative to the common treatments. Recently, the supercoiled conformation of a p53-encoding plasmid proved to be more efficient in cell transfection and protein expression than the
Jeffrey W Guthrie et al.
Analytica chimica acta, 853, 676-681 (2014-12-04)
An immunoassay based on CE-LIF was developed for the simultaneous detection of cyclobutane pyrimidine dimers (CPDs) and pyrimidine 6-4 pyrimidone photoproducts (6-4PPs) in genomic DNA irradiated with UVB or natural sunlight. Human cells were first exposed to varying amounts of
Sarah Afshordel et al.
Prostaglandins, leukotrienes, and essential fatty acids, 92, 23-31 (2014-06-29)
The present study investigated the effects of orally administered long chain omega-3 polyunsaturated fatty acids (PUFA) on mitochondrial function and processing of the amyloid precursor protein (APP) in brains of young (3 months old) and aged (24 months old) NMRI-mice.
Ken Ye et al.
PloS one, 9(6), e99410-e99410 (2014-06-12)
Infrapatellar fat pad adipose stem cells (IPFP-ASCs) have been shown to harbor chondrogenic potential. When combined with 3D polymeric structures, the stem cells provide a source of stem cells to engineer 3D tissues for cartilage repair. In this study, we
Isaac B Roll et al.
Journal of hazardous materials, 288, 89-96 (2015-02-24)
With the population of developed nations spending nearly 90% of their time indoors, indoor air quality (IAQ) is a critical indicator of human health risks from inhalation of airborne contaminants. We present a novel approach for qualitative monitoring of IAQ
Qi Zeng et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 981-982, 33-39 (2015-01-18)
Analysis of blood proteins holds critical promise for in depth understanding of physiological states. Protein content of hemolymph from Drosophila melanogaster is of particular analytical interest because the insect open circulatory system involves chemical signaling through the hemolymph. The challenge
Giovanni Forte et al.
Annali dell'Istituto superiore di sanita, 41(2), 213-216 (2005-10-26)
Although some studies suggested a link between exposure to trace elements and development of multiple sclerosis (MS), clear information on their role in the aetiology of MS is still lacking. In this study the concentrations of Al, Ba, Be, Bi
Hiroyuki Kimura et al.
Journal of labelled compounds & radiopharmaceuticals, 57(12), 680-686 (2014-10-09)
Microwave technology has been successfully applied to enhance the effectiveness of radiolabeling reactions. The use of a microwave as a source of heat energy can allow chemical reactions to proceed over much shorter reaction times and in higher yields than
Rachel M Stenger et al.
Clinical and vaccine immunology : CVI, 21(5), 641-650 (2014-03-07)
Knowledge of naturally processed Bordetella pertussis-specific T cell epitopes may help to increase our understanding of the basis of cell-mediated immune mechanisms to control this reemerging pathogen. Here, we elucidate for the first time the dominant major histocompatibility complex (MHC)
Xianyu Chen et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 970, 121-130 (2014-09-28)
The aim of this study was to develop an analytical method for the quantification of organochlorine (OC), organophosphate (OP), carbamate, and pyrethroid insecticide residues in cow milk, human milk, and baby formula. A total of 25 compounds were included in
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