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关键词:'91861'
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M F Kirby et al.
Aquatic toxicology (Amsterdam, Netherlands), 81(3), 233-244 (2007-01-24)
The extent to which biological systems interact in fish from multi-contaminant areas needs to be understood for full interpretation of monitoring data. This study investigates the interaction between two biomarkers, ethoxyresorufin-O-deethylase (EROD) activity and plasma vitellogenin (VTG) in the European
Polycyclic aromatic hydrocarbons: 15 Listings - benz[a]anthracene, benzo[b]fluoranthene, benzo[j]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[a,h]anthracene, 7H-dibenzo[c,g]carbazole, dibenzo[a,e]pyrene, dibenzo[a,h]pyrene, dibenzo[a,i]pyrene, dibenzo[a,l]pyrene, indeno[1,2,3-cd]pyrene, 5-methylchrysene.
Report on carcinogens : carcinogen profiles, 12, 353-361 (2011-08-25)
Xin-Chun Zhao et al.
EBioMedicine, 53, 102689-102689 (2020-03-03)
How the oncoprotein epidermal growth factor receptor (EGFR) evades proteolytic degradation and accumulates in non-small cell lung cancer (NSCLC) remains unclear, and ubiquitin pathway genes (UPGs) that are critical to NSCLC needs to be systematically identified. A total of 696
S C Corgié et al.
Biodegradation, 17(6), 511-521 (2006-02-18)
Bioremediation technologies of Polycyclic Aromatic Hydrocarbons (PAH) are often limited by the recalcitrance to biodegradation of high molecular weight (HMW) PAH. Rhizosphere is known to increase the biodegradation of PAH but little is known about the biodegradability of these HMW
Sander Delahaye et al.
Journal of chromatography. A, 1258, 152-160 (2012-09-04)
Supercritical fluid chromatography (SFC) is attributed many advantages over high performance liquid chromatography (HPLC). Next to the fact that SFC is greener than HPLC, which is especially important for preparative separations, SFC is claimed to be able to deliver faster
Santiago A Bortolato et al.
Analytical chemistry, 80(21), 8276-8286 (2008-10-02)
This work presents a novel approach for the simultaneous ultratrace determination of benzo[ a]pyrene and dibenzo[ a,h]anthracene, the two most carcinogenic polycyclic aromatic hydrocarbons (PAHs), in a very interfering environment, combining the recently discovered ability of the nylon membrane to
Katarzyna Skupinska et al.
Toxicology in vitro : an international journal published in association with BIBRA, 23(5), 763-771 (2009-04-14)
Polycyclic aromatic hydrocarbons (PAHs)--environmental carcinogens--are metabolized by CYP1A1 and CYP1A2 enzymes to oxy-derivatives, which are able to bind to DNA and initiate carcinogenesis. PAHs induce CYP1A1 and CYP1A2 activity, which increases the risk of development of carcinogenesis. Isothiocyanates (ITCs), naturally
Faiqa Aziz et al.
Ecotoxicology and environmental safety, 109, 77-84 (2014-09-23)
Present study investigates the occurrence, distribution and sources of ∑17 polycyclic aromatic hydrocarbons (PAHs) in the surface water of Soan River, Pakistan. The concentrations of total PAHs ranged from 61 to 207 ng/l. Low molecular weight (LMW) PAHs were recorded
Julia E Heck et al.
Environmental research, 127, 1-6 (2013-10-22)
Little is known about the etiology of neuroblastoma, the most common cancer in infancy. In this study, we examined maternal exposure to ambient air toxics in pregnancy in relation to neuroblastoma in the child. We ascertained all cases of neuroblastoma
N Winker et al.
Journal of applied toxicology : JAT, 15(1), 59-62 (1995-01-01)
Benzo[a]pyrene, benzo[b]fluoroanthene and dibenzo[a,h]anthracene dissolved in a 1:2 mixture of dimethylsulphoxide (DMSO) and water were administered to two groups of female mice, each group containing 15 mice. The doses were administered orally (via gavage) at the respective rates of 1
Seker Fatma Aygün
Journal of separation science, 28(17), 2370-2373 (2005-12-14)
A simultaneous determination method for the analysis of benzo[a]pyrene (BaP) and dibenzo[a,h]anthracene (DahA) in the filter tar of Turkish cigarettes has been developed. The method involved (a) the extraction of BaP and DahA with n-hexane from ACN solution in which
Wenpeng Zhang et al.
Journal of chromatography. A, 1365, 19-28 (2014-09-15)
In this work, we interestingly happened to observe the adsorption of stainless steel sample loop of HPLC. The adsorptive behaviors of the stainless steel loop toward different kinds of compounds were studied, including polycyclic aromatic hydrocarbons (PAHs), halogeno benzenes, aniline
B Z Zhong et al.
Mutation research, 326(2), 147-153 (1995-02-01)
Benz[a]anthracene (BA), dibenz[a,h]anthracene (DBA) and dibenzo[a,i]pyrene (DBP) are polycyclic aromatic hydrocarbons (PAHs) found in incomplete combustion products of fossil fuels, coal tar, and other organic materials. Workers in related industries may be exposed to these chemicals by inhalation. The information
A L Juhasz et al.
Letters in applied microbiology, 30(5), 396-401 (2000-05-03)
The ability of Stenotrophomonas maltophilia strain VUN 10,003 to degrade and detoxify high molecular weight polycyclic aromatic hydrocarbons (PAHs) was evaluated in a basal liquid medium. Using high cell density inocula of strain VUN 10,003, the concentration of pyrene, fluoranthene
Heinz Frank et al.
Chemical research in toxicology, 24(12), 2258-2268 (2011-11-18)
The synthesis of the 8 possible stereoisomeric diol epoxides (DEs) at the terminal benzo ring of carcinogenic dibenz[a,h]anthracene (DBA) is reported. trans-3,4-Dihydroxy-3,4-dihydro-DBA (1) afforded the 4 bay region DEs: the enantiomeric pairs of the anti diastereomers (+)-3/(-)-3 and of the
A L Juhasz et al.
Journal of industrial microbiology & biotechnology, 28(2), 88-96 (2002-06-21)
Large inocula of Stenotrophomonas maltophilia VUN 10,003 were used to investigate bacterial degradation of benzo[a]pyrene and dibenz[a,h]anthracene. Although strain VUN 10,003 was capable of degrading 10-15 mg (-1) of the five-ring compounds in the presence of pyrene after 63 days
S Nesnow et al.
Carcinogenesis, 15(10), 2225-2231 (1994-10-01)
The major routes of metabolic activation of dibenz[a,h]-anthracene (DBA) have been studied in transformable C3H10T1/2CL8 (C3H10T1/2) mouse embryo fibroblasts in culture. The morphological transforming activities of three potential intermediates formed by metabolism of DBA by C3H10T1/2 cells, trans-3,4-dihydroxy-3,4-dihydro-DBA-(DBA-3,4-diol), trans-dihydroxy-3,4-dihydro-DBA-anti-1,2-oxide (DBA-3,4-diol-1,2-oxide)
H-W Wang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 40(5), 653-661 (2002-04-17)
The effect of airborne frying-meat emission particulate (FMEP) on cytochrome P450 (P450)-dependent monooxygenase was determined using human lung adenocarcinoma cell line CL5 treated with organic extract of FMEP prepared from beef, fish or pork. Treatment with fish FMEP extract caused
P Sartorelli et al.
Toxicology and industrial health, 17(1), 17-21 (2002-05-15)
To understand the dermal uptake of chemicals bound to soil and dust, information on the neat substance is helpful but does not seem sufficient. Because of its content of polycyclic aromatic hydrocarbons (PAHs) coal is suspected to be carcinogenic. However
M Shou et al.
Archives of biochemistry and biophysics, 328(1), 201-207 (1996-04-01)
The metabolic activation of the potent carcinogen dibenzo[a,h]anthracene (DB[a,h]A) was investigated with recombinant human cytochrome P450 enzymes 1A2, 2B6, 2C8, 2C9, 2E1, 3A3, 3A4, and 3A5 expressed in hepatoma G2 cells and with 14 different human liver microsomes. Three dihydrodiols
K B Okona-Mensah et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 43(7), 1103-1116 (2005-04-19)
Evidence suggests that people living in urban areas have an increased risk of lung cancer due to higher levels of air pollution in these areas. Benzo[a]pyrene (B[a]P) is currently used as the main indicator of carcinogenic polycyclic aromatic hydrocarbons (PAHs)
Ana Passuello et al.
Environment international, 36(6), 577-583 (2010-05-18)
Because of its benefits to soil and crops, sewage sludge application on agricultural soils is a managing practice of increasing use. However, this practice may lead to contamination of the food chain, especially by persistent organic pollutants (POPs). The main
A Perico et al.
Archives of environmental health, 56(6), 506-512 (2002-04-18)
In this study, the authors evaluated exposure to airborne polycyclic aromatic hydrocarbons (PAHs) in workers exposed to exhaust gas from cars, and they assessed the efficiency of urinary 1-hydroxypyrene as an indicator of exposure to pyrene and PAHs. The authors
Hang Thi Nguyen et al.
TheScientificWorldJournal, 10, 20-37 (2010-01-12)
Concentrations of seven polycyclic aromatic hydrocarbon (PAH) compounds - benzo(a)anthracene (BaA), chrysene (CHRY), benzo(b)fluoranthene (BbF), benzo(k)fluoranthene (BkF), dibenz(a,h)anthracene (DahA), indeno(1,2,3-cd)pyrene (I123P), and benzo(a)pyrene (BaP) - in air were measured as the sum of gas and particle fractions at 32 monitoring
Daphnee S Pushparajah et al.
Mutagenesis, 23(4), 299-308 (2008-04-05)
The cytosolic glutathione S-transferases (GSTs) comprise a pivotal enzyme system protecting the cell from electrophilic compounds. It plays a major role in the detoxication of the primary and dihydrodiol epoxides of polycyclic aromatic hydrocarbons (PAHs), so that modulation of this
James W Flesher et al.
Biochemical and biophysical research communications, 290(1), 275-279 (2002-01-10)
Early carcinogenicity tests found no evidence of activity for picene but found considerable initiating and carcinogenic activity for dibenz[a,h]anthracene (DBA). More recent investigation suggested that both pentacyclics were complete carcinogens when administered as single sc injections in NMRI mice, despite
K Chroust et al.
Mutation research, 498(1-2), 169-179 (2001-10-24)
Sensitivity of transgenic Drosophila melanogaster with expression of a human gene encoding the glutathione S-transferase alpha subunit (GSTA1-1) to 1,2:5,6-dibenzanthracene (DBA) and 1,2-dichloroethane (DCE) was investigated in the somatic mutation and recombination test (SMART). We performed the same assay in
Juan Zhang et al.
Journal of chromatography. A, 1388, 9-16 (2015-03-03)
Zeolitic imidazolate frameworks (ZIFs), a subfamily of metal-organic frameworks (MOFs), have received considerable attention as a novel porous material for sample preparation due to their fascinating structures and unique properties. Here, we developed a novel bio-inspired polydopamine (PDA) method to
Zhi-Xin Yuan et al.
Chemical research in toxicology, 16(12), 1581-1588 (2003-12-19)
Benzo[b]phenanthro[2,3-d]thiophene (BPT), a thia analogue of dibenz[a,h]anthracene (DBA), is a carcinogenic environmental pollutant. We have examined the metabolism of BPT by rodent liver microsomes to investigate the mechanism by which BPT produces mutagenic and carcinogenic effects. Both rat and mouse
Zhongming Zheng et al.
Environmental science and pollution research international, 10(3), 173-176 (2003-07-09)
Indigenous soil microorganisms are used for the biodegradation of petroleum hydrocarbons in oily waste residues from the petroleum refining industry. The objective of this investigation was to determine the potential of indigenous strains of fungi in soil contaminated with petroleum
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