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Emmanuelle Berthelot et al.
European journal of clinical investigation, 44(10), 982-988 (2014-09-05)
Coupled arterial and left ventricular properties are poorly documented in acute heart failure. The aim of this prospective noninvasive study was to document early changes in ventricular-arterial coupling in patients with acutely decompensated HF (ADHF). We studied 19 patients hospitalized
Kimberly Brinker et al.
MMWR. Morbidity and mortality weekly report, 63(53), 1233-1237 (2015-01-13)
On November 30, 2012, at approximately 7:00 am, a freight train derailed near a small town in New Jersey. Four tank cars, including a breached tank car carrying vinyl chloride, landed in a tidal creek. Vinyl chloride, a colorless gas
Hong-chun Zhao et al.
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 41(12), 945-949 (2007-03-10)
To study the expression of S phase kinase associated protein 2 (Skp2), phosphatase and tensin homolog deleted on chromosome ten (PTEN) in human laryngeal carcinoma and precancerous lesions, to explore their relations and clinical significance. Formalin-fixed and paraffin-embedded tissues from
Huseyin Anil Korkmaz et al.
Paediatrics and international child health, 34(3), 198-202 (2014-03-14)
In clinical trials, diphtheria, tetanus and acellular pertussis vaccines have been shown to be less reactogenic than whole-cell combination vaccines. To evaluate diphtheria and tetanus toxoids combined with acellular pertussis (DTaP) and diphtheria and tetanus toxoids combined with whole-cell pertussis
Daniel I Swerdlow et al.
Lancet (London, England), 385(9965), 351-361 (2014-09-30)
Statins increase the risk of new-onset type 2 diabetes mellitus. We aimed to assess whether this increase in risk is a consequence of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), the intended drug target. We used single nucleotide polymorphisms in the HMGCR
Daniel P Petrylak et al.
The Lancet. Oncology, 16(4), 417-425 (2015-03-07)
Patients with metastatic castration-resistant prostate cancer have few treatment options. We investigated the safety and efficacy of lenalidomide, an immunomodulatory agent with anti-angiogenic properties, in combination with docetaxel and prednisone in chemotherapy-naive patients with metastatic castration-resistant prostate cancer. In this
Rachel S Kerr et al.
The Lancet. Oncology, 17(11), 1543-1557 (2016-09-24)
Antiangiogenic agents have established efficacy in the treatment of metastatic colorectal cancer. We investigated whether bevacizumab could improve disease-free survival in the adjuvant setting after resection of the primary tumour. For the open-label, randomised, controlled QUASAR 2 trial, which was
Ajay Vora et al.
The Lancet. Oncology, 14(3), 199-209 (2013-02-12)
Minimal residual disease (MRD) is the most sensitive and specific predictor of relapse risk in children with acute lymphoblastic leukaemia (ALL) during remission. We assessed whether treatment intensity could be adjusted for children and young adults according to MRD risk
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