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A Ravindranathan et al.
Neuroreport, 7(15-17), 2707-2711 (1996-11-04)
Using oligonucleotide primers, we have amplified and sequenced the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors from the brain of 17-day-old chick embryos. Both flip and flop isoforms of each of these glutamate receptors (GluR) were identified and cloned. Nucleotide comparisons showed that
Stefan Aretz et al.
Human mutation, 26(6), 513-519 (2005-11-16)
Germline mutations in the STK11 gene have been identified in 10-70% of patients with Peutz-Jeghers syndrome (PJS), an autosomal-dominant hamartomatous polyposis syndrome. A second locus was assumed in a large proportion of PJS patients. To date, STK11 alterations comprise mainly
Nhan Hyung et al.
Journal of pediatric surgery, 52(7), 1152-1155 (2016-11-27)
To determine the incidence of intestinal mucosal injury before and after transfusions in premature infants. Urine was collected throughout the hospital stay of 62 premature infants and specimens obtained within 24h before and after transfusion were assayed for intestinal fatty
J L Blank et al.
The Journal of biological chemistry, 271(10), 5361-5368 (1996-03-08)
Mitogen-activated protein/ERK kinase kinases (MEKKs) phosphorylate and activate protein kinases which in turn phosphorylate and activate the p42/44 mitogen-activated protein kinase (MAPK), c-Jun/stress-activated protein kinases (JNKs), and p38/Hog1 kinase. We have isolated the cDNAs for two novel mammalian MEKKs (MEKK
Maria Bai et al.
Human pathology, 38(1), 103-113 (2006-09-05)
The expression of various bcl2 family proteins has been reported in Hodgkin and Reed-Sternberg cells, but the proteins bad, bid, and bim have not been analyzed in classical Hodgkin's lymphomas (HLs). This study aimed to investigate the expression of the
S Kimura et al.
Biochemistry, 28(9), 3798-3803 (1989-05-02)
A novel P450 cDNA was isolated from a rat lung lambda gt11 library by hybridization with the rat P450 IIB1 cDNA probe. The cDNA-deduced amino acid sequence of this clone was 71% and 73% similar to rat IIA1 and IIA2
Jacqueline Bachofner et al.
Swiss medical weekly, 148, w14560-w14560 (2018-01-30)
The introduction of direct acting antivirals (DAAs) for the therapy of chronic hepatitis C (CHC) has revolutionised treatment and marks a paradigm shift in the approach to this disease, rendering interferon-based therapies obsolete. We retrospectively and prospectively evaluated treatment results
Eva-Katrin Bentz et al.
Reproductive sciences (Thousand Oaks, Calif.), 14(7), 705-709 (2007-11-15)
The relation between genetic variation of the androgen metabolism and transsexualism is unknown. In a case-control study of 100 male-to-female (MtF) transsexuals, 47 female-to-male (FtM) transsexuals, and 1670 controls, the authors assess allele and genotype frequencies of the steroid 5-alpha
Michael E Rytting et al.
Cancer, 120(23), 3660-3668 (2014-07-22)
Various trials have reported improved outcomes for adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL) who received treatment with pediatric-based regimens. Those reports prompted the current investigation of the pediatric augmented Berlin-Frankfurt-Münster (ABFM) regimen in AYA patients. The
Szlavik et al.
Organic letters, 2(15), 2347-2349 (2000-08-10)
A convenient and effective method for the preparation of perfluoroalkylated ethenes is described. First, the free radical addition of perfluoroalkyl iodides to trimethylvinylsilane in the presence of AIBN gave iodoethylsilane intermediates (F(CF(2))(n)()CH(2)CHISiMe(3), n = 4 (1), 6 (2), 8 (3)
Elizabeth A Hunsperger et al.
PLoS neglected tropical diseases, 8(10), e3171-e3171 (2014-10-21)
Commercially available diagnostic test kits for detection of dengue virus (DENV) non-structural protein 1 (NS1) and anti-DENV IgM were evaluated for their sensitivity and specificity and other performance characteristics by a diagnostic laboratory network developed by World Health Organization (WHO)
Carboxyterminal cleavage of the chemokines MIG and IP-10 by gelatinase B and neutrophil collagenase.
Philippe E Van den Steen et al.
Biochemical and biophysical research communications, 310(3), 889-896 (2003-10-11)
Proteolytic processing is an important regulatory mechanism for chemokines. Matrix metalloproteinases (MMPs), such as gelatinase A/MMP-2 and gelatinase B/MMP-9, are known to process the aminoterminal end of various chemokines, including interleukin-8 (IL-8/CXCL-8) and monocyte chemotactic protein-3 (MCP-3/CXCL-7). In the present
Anni Keränen et al.
Journal of environmental management, 160, 105-112 (2015-06-21)
Anion exchange materials were prepared from pine sawdust (Pinus sylvestris, PSD) through cationizing treatment with N-(3-chloro-2-hydroxypropyl) trimethyl ammonium chloride (CHMAC) in the presence of NaOH. Response surface methodology (RSM) was used to find the optimal reaction conditions. Three factors were
E Scala et al.
Allergy, 70(8), 933-943 (2015-04-24)
Nonspecific lipid transfer proteins (nsLTPs) represent a major cause of systemic food allergic reactions in the Mediterranean area. This study investigate hierarchical patterns and cluster relationships of IgE sensitization to different nsLTPs, and the relationship to clinical allergy in a
G J Tangelder et al.
The American journal of physiology, 268(2 Pt 2), H909-H915 (1995-02-01)
A method is presented to assess in vivo in transparent tissues the leukocyte subtypes that roll in microvessels. In nine rabbits anesthetized with ketamine-xylazine, leukocyte nuclei were stained in situ with acridine yellow (3 mg/kg i.v. for 5 min). Intravital
H Porst
Der Urologe. Ausg. A, 37(4), 410-416 (1998-09-17)
An analysis of the presently available results concerning transurethral application of Alprostadil with MUSE (Medicated Urethral System for Erection) up to 1000 micrograms indicates a 20-30% lower efficacy if compared to 20 micrograms i.c. injected Alprostadil. Whereas in prospective home-treatment
Guilherme A F Rollin et al.
Clinical endocrinology, 82(6), 793-800 (2014-11-08)
To analyse the performance of the desmopressin (DDAVP) test in the diagnosis of Cushing's disease (CD). This was a prospective cohort study of 124 patients with suspected hypercortisolism who were recruited from an outpatient endocrinology clinic and investigated for Cushing's
S H Lee et al.
American journal of clinical pathology, 92(3), 342-347 (1989-09-01)
Antibodies against Mycoplasma pneumoniae in the sera of patients and normal adult controls were measured by a standard complement fixation (CF) test, a commercial immunofluorescence (IF) test (CROWNTITRE), and a commercial enzyme-linked immunosorbent assay (ELISA) (MYCOPLASMELISA). The findings showed that
Prasanna K Dadi et al.
International journal of biological macromolecules, 45(1), 72-79 (2009-04-21)
We have studied the inhibitory effect of five polyphenols namely, resveratrol, piceatannol, quercetin, quercetrin, and quercetin-3-beta-D glucoside on Escherichia coli ATP synthase. Recently published X-ray crystal structures of bovine mitochondrial ATP synthase inhibited by resveratrol, piceatannol, and quercetin, suggest that
F Alan Barber et al.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 29(11), 1834-1839 (2013-11-12)
The purpose of this study was to evaluate the long-term in vivo degradation of biocomposite suture anchors made of poly L-lactide-co-glycolide (PLLA/PGA) and β-tricalcium phosphate (β-TCP). Starting in 2008, the in vivo biological behavior of a biocomposite suture anchor was studied in
R H Hildebrandt et al.
Human pathology, 28(12), 1387-1395 (1998-01-07)
Inhibins are peptide hormones that participate in the regulation of the pituitary-gonadal feedback system and are selectively expressed by cells of sex cord-stromal derivation. To determine the efficacy of this marker for distinguishing granulosa cell tumors, 134 primary and metastatic
Tsui-Ling Ko et al.
Cell transplantation, 24(11), 2251-2262 (2014-10-08)
The success rate in previous attempts at transforming human umbilical mesenchymal stem cells (HUMSCs) isolated from Wharton's jelly of the umbilical cord into dopaminergic cells was a mere 12.7%. The present study was therefore initiated to establish a more effective
Martha Hentemann et al.
Fertility and sterility, 91(3), 878-883 (2008-03-07)
To develop sequential media for extended culture of embryos in human IVF, with use of a mouse embryo assay. The BlastAssist system was developed. Blastocyst culture has been our routine method since 1994, using earlier media IVF and M3 in
S K Moore et al.
DNA and cell biology, 9(6), 387-400 (1990-07-01)
The nucleotide sequence of a 6-kb region containing the gene for mouse 84-kD heat shock protein, HSP84, was determined. The hsp84 gene codes for a 5,500-base transcript and consists of 11 exons and 10 introns, ranging in length from 94
Hana Dobiasova et al.
FEMS microbiology ecology, 85(3), 604-611 (2013-05-18)
Commensal Escherichia coli isolates from healthy zoo animals kept in Ostrava Zoological Garden, Czech Republic, were investigated to evaluate the dissemination of extended-spectrum beta-lactamase (ESBL) and plasmid-mediated quinolone resistance (PMQR) genes. A total of 160 faecal samples of various animal
Aejaz Nasir et al.
Cancer genomics & proteomics, 20(6), 522-530 (2023-10-27)
P21 is a cyclin-dependent kinase inhibitor regulating the cell cycle as a tumor suppressor. Using a p21 immunohistochemistry (IHC) assay, we compared tumor p21 levels with conventional clinico-pathological criteria in primary pancreatic endocrine tumor subsets with and without liver metastases.
T M Forte et al.
Journal of lipid research, 40(7), 1276-1283 (1999-07-07)
Lecithin:cholesteryl acyltransferase (LCAT) deficiency resulting from targeted disruption of the Lcat gene in the mouse is associated with dramatic decreases in HDL concentration and the accumulation of nascent HDL in the plasma. We examined whether LCAT deficiency in mice is
Somayeh Hosseinzadeh et al.
Pharmaceutical biology, 51(2), 240-245 (2012-11-09)
For many years it has been known that lead is life-threatening, not only as an air pollutant but also because of it has been associated with several conditions including neurodegenerative disease. Curcumin (the principal curcuminoid found in turmeric) has demonstrated
Niranjan Awasthi et al.
Molecular cancer therapeutics, 21(7), 1149-1159 (2022-05-03)
Gastric adenocarcinoma (GAC) is the third most common cause of cancer-related deaths worldwide. Combination chemotherapy remains the standard treatment for advanced GAC. Liposomal irinotecan (nal-IRI) has improved pharmacokinetics (PK) and drug biodistribution compared with irinotecan (IRI, CPT-11). Angiogenesis plays a
Carrie E Gifford et al.
Cytometry. Part B, Clinical cytometry, 86(4), 263-271 (2014-03-13)
X-linked lymphoproliferative disease is caused by mutations in two genes, SH2D1A and XIAP/BIRC4. Flow cytometric methods have been developed to detect the gene products, SAP and XIAP. However, there is no literature describing the accuracy of flow cytometric screening performed
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