CN
95-15-8
应用筛选条件
关键词:'95-15-8'
显示 1-30 共 622 条结果 关于 "95-15-8" 范围 论文
Martin R Stockler et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(13), 1309-1316 (2014-04-02)
To determine the effects of bevacizumab on patient-reported outcomes (PROs; secondary end point) in the AURELIA trial. Patients with platinum-resistant ovarian cancer were randomly assigned to chemotherapy alone (CT) or with bevacizumab (BEV-CT). PROs were assessed using the European Organisation
Rong-Miao Zhou et al.
Ai zheng = Aizheng = Chinese journal of cancer, 25(9), 1113-1119 (2006-09-13)
Xeroderma pigmentosum group C(XPC) gene is involved in nucleotide excision repair (NER). Single nucleotide polymorphisms (SNP) in XPC gene may affect DNA repairing capacity and genetic susceptibility to cancer. This study was to investigate the correlation of XPC exon 8
Maria Teresa Bortolin et al.
Cytokine, 60(1), 90-95 (2012-07-17)
Recent studies suggest a powerful prognostic value for blood cytokine levels in different diseases. Non-Hodgkin lymphoma (NHL) still represents one of the main causes of death in the HIV setting, with a wide variation in outcome and survival among patients.
Mikhail Kosiborod et al.
JAMA, 312(21), 2223-2233 (2014-11-18)
Hyperkalemia is a common electrolyte abnormality that may be difficult to manage because of a lack of effective therapies. Sodium zirconium cyclosilicate is a nonabsorbed cation exchanger that selectively binds potassium in the intestine. To evaluate the efficacy and safety
Lin Yang et al.
Zhonghua yi xue za zhi, 85(33), 2312-2316 (2005-12-03)
To investigate the impact of GSTM1, GSTT1 and NQO1 genotypes on susceptibility to acute myeloid leukemia (AML) and recurrent chromosome translocations of AML. GSTT1, GSTM1 and NQO1 genotypes were detected in 228 adult patients with de novo AML and 241
Theodore H Welling et al.
Cancer investigation, 30(10), 689-697 (2012-10-18)
Tumor immune responses have prognostic importance to hepatocellular carcinoma (HCC). Serum cytokines may differentiate HCC patients from cirrhotic patients or have prognostic significance. Serum IL-8 was elevated in 90 HCC patients compared to 180 cirrhotic controls, whereas IL-1β, IL-2, IL-4
Takara L Stanley et al.
JAMA, 312(4), 380-389 (2014-07-20)
Among patients infected with human immunodeficiency virus (HIV), visceral adiposity is associated with metabolic dysregulation and ectopic fat accumulation. Tesamorelin, a growth hormone-releasing hormone analog, specifically targets visceral fat reduction but its effects on liver fat are unknown. To investigate
Anne M Traynor et al.
Investigational new drugs, 28(1), 91-97 (2009-02-25)
The objective of ECOG 1503 was to determine the response rate of this combination in the second-line treatment of advanced NSCLC. Triapine 105 mg/m(2) IV on days 1, 8, and 15, and gemcitabine 1,000 mg/m(2) on days 1, 8, and
David H Winslow et al.
Sleep, 35(11), 1529-1539 (2012-11-02)
To evaluate safety and efficacy of phentermine 15 mg plus extended-release topiramate 92 mg for treatment of moderate to severe obstructive sleep apnea (OSA) in obese adults. This phase 2, randomized, double-blind, placebo-controlled study included 2-week screening and 28-week treatment
Paul Haggarty et al.
The British journal of nutrition, 109(5), 898-905 (2012-11-22)
The aims of the present study were to determine compliance with current advice on vitamin D and to assess the influence of season, dietary intake, supplement use and deprivation on vitamin D status in pregnant mothers and newborns in the
Anna M van Opstal et al.
The Lancet. Neurology, 16(2), 115-122 (2016-12-19)
Previous work suggests that impairments of cerebrovascular flow or reactivity might be early markers of cerebral amyloid angiopathy (CAA). Hereditary cerebral haemorrhage with amyloidosis-Dutch type (HCHWA-D) is a genetic form of CAA that can be diagnosed before the onset of
Catia Cillóniz et al.
PloS one, 12(8), e0182436-e0182436 (2017-08-09)
We aimed to investigate the association between the time to positivity of blood culture (TTP) with clinical outcome and severity of pneumococcal bacteremic pneumonia. Prospective observational study carried out in 278 hospitalized adult CAP patients with positive blood culture for
E Vergnaud et al.
British journal of anaesthesia, 114(1), 103-109 (2014-10-16)
Postoperative fluid management can be challenging in children after haemorrhagic surgery. The goal of this study was to assess the ability of dynamic cardiovascular variables measured using bioreactance (NICOM®, Cheetah Medical, Tel Aviv, Israel) to predict fluid responsiveness in postoperative
Kênia Kp Menezes et al.
Respiratory care, 63(7), 920-933 (2018-05-31)
The aim of this study was to systematically review all current interventions that have been utilized to improve respiratory function and activity after stroke. Specific searches were conducted. The experimental intervention had to be planned, structured, repetitive, purposive, and delivered
Pavel Rossner et al.
Mutation research, 713(1-2), 76-82 (2011-06-21)
Air pollution causes oxidative damage to macromolecules, chromosomal aberrations and changes in gene expression. We investigated the levels of oxidative stress markers [8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG), 15-F(2t)-isoprostane (15-F2t-IsoP), protein carbonyls] and cytogenetic parameters [genomic frequency of translocations (F(G)/100), percentage of aberrant cells
Masafumi Kimura et al.
Anesthesiology, 123(4), 899-908 (2015-08-06)
Patients with neuropathic pain show reduced endogenous analgesia induced by a conditioned noxious stimulus. Here, the authors tested whether peripheral nerve injury impairs descending noradrenergic inhibition from the locus coeruleus (LC) after L5-L6 spinal nerve ligation (SNL) in rats. A
E I Ekinci et al.
Clinical endocrinology, 82(4), 604-610 (2014-08-01)
Thyroid peroxidase antibodies (TPOAb) and thyroglobulin antibodies (TGAb) are frequently measured to investigate thyroid dysfunction in pregnancy. Despite the recognized fall of these autoantibodies in pregnancy, there is limited guidance on the timing of such testing. We assessed optimal test
Marc Lilot et al.
Anesthesia and analgesia, 117(1), 259-264 (2013-04-18)
In this randomized, prospective trial, we sought to determine the effective dose of hypobaric ropivacaine with sufentanil providing 95% success (ED95) in spinal anesthesia for traumatic femoral neck surgery in the elderly. Sixty-eight elderly patients with unilateral hip fracture randomly
Shyam Sundar et al.
Tropical medicine & international health : TM & IH, 18(1), 96-100 (2012-11-10)
Standard treatment of Indian post-kala-azar dermal leishmaniasis (PKDL) is unsatisfactory because to achieve therapeutic effectiveness, heroic courses of parenteral and toxic agents have to be administered. Our objective was to evaluate oral miltefosine for its potential to provide effective as
O Katopodis et al.
Cancer chemotherapy and pharmacology, 74(2), 333-340 (2014-06-16)
Intravenous gemcitabine is the standard of care for patients with metastatic cancer of the pancreas. Gemcitabine-based chemotherapy combinations, either doublets or triplets, have been tested in the past but have offered a small advantage (Brodoefel et al. in Eur J
Jung Yong Hong et al.
Cancer chemotherapy and pharmacology, 73(1), 125-130 (2013-10-29)
Statins have potential antineoplastic properties via arrest of cell-cycle progression and induction of apoptosis. A previous study demonstrated in vitro and in vivo antineoplastic synergism between statins and gemcitabine. The present randomized, double-blinded, phase II trial compared the efficacy and
V Vaccaro et al.
BioMed research international, 2014, 351252-351252 (2014-05-31)
No established chemotherapeutic regimen exists for the treatment of recurrent malignant gliomas (rMGs). Herein, we report the activity and safety results of the bevacizumab (B) plus fotemustine (FTM) combination for the treatment of rMGs. An induction phase consisted of B
Michael J Chao et al.
Human molecular genetics, 19(18), 3679-3689 (2010-07-17)
Multiple sclerosis (MS) susceptibility is characterized by maternal parent-of-origin effects and increased female penetrance. In 7796 individuals from 1797 MS families (affected individuals n = 2954), we further implicate epigenetic modifications within major histocompatibility complex (MHC) class II haplotypes as
Kiyohide Fujimoto et al.
Hinyokika kiyo. Acta urologica Japonica, 57(4), 177-183 (2011-06-08)
In this prospective multicenter study, we investigated the changes in serum prostate-specific antigen (PSA) and testosterone levels after treatment with antiandrogen chlormadinone acetate (CMA) in patients with benign prostatic hyperplasia (BPH). The inclusion criteria for the patients were as follows
S F Paul Man et al.
Therapeutic advances in respiratory disease, 3(2), 73-80 (2009-05-26)
Several studies suggest that inhaled and oral corticosteroids repress systemic inflammation in chronic obstructive pulmonary disease (COPD). However, the cytokines that may respond to these medications are unclear. We used data from 41 patients with a history of stable moderate
Hideo Kato et al.
Drugs in R&D, 17(1), 177-187 (2017-01-08)
Amikacin has been one of the important antimicrobial agents against Gram-negative pathogens. However, there is discrepancy regarding the amikacin initial dosage, with some reports recently recommending ≥25 mg/kg and others the conventional dosage (15-20 mg/kg). Hence, we evaluated the optimal initial dosing
Guilherme A F Rollin et al.
Clinical endocrinology, 82(6), 793-800 (2014-11-08)
To analyse the performance of the desmopressin (DDAVP) test in the diagnosis of Cushing's disease (CD). This was a prospective cohort study of 124 patients with suspected hypercortisolism who were recruited from an outpatient endocrinology clinic and investigated for Cushing's
Yolanda Picó et al.
Analytical and bioanalytical chemistry, 407(15), 4247-4259 (2015-01-31)
The accurate determination of perfluoroalkyl substances (PFSAs) in water, sediment, fish, meat, and human milk was achieved by ultrahigh-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-QqTOF-MS) with an ABSciex Triple TOF®. A group of 21 PFSAs was selected as target to
Mario Falchi et al.
Nature genetics, 41(8), 915-919 (2009-07-07)
A high melanocytic nevi count is the strongest known risk factor for cutaneous melanoma. We conducted a genome-wide association study for nevus count using 297,108 SNPs in 1,524 twins, with validation in an independent cohort of 4,107 individuals. We identified
S H Ibbotson et al.
The British journal of dermatology, 166(2), 380-388 (2011-10-05)
There is marked interpatient variation in responses to psoralen-ultraviolet A (PUVA) photochemotherapy. Identification of molecular biomarkers of PUVA sensitivity may facilitate treatment predictability.The glutathione S-transferases (GSTs) influence cutaneous defence against UV radiation-induced oxidative stress and are therefore candidate biomarkers of
1/21