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显示 1-30 共 273 条结果 关于 "95-31-8" 范围 论文
Hsin-Hung Cheng et al.
Journal of gastroenterology and hepatology, 25(8), 1443-1451 (2010-07-28)
Helicobacter pylori (H. pylori) infection induces cytokine production and is associated with gastrointestinal diseases. This study examined the relationship of gene polymorphisms, including interleukin (IL)-1beta, -10, -8, and tumor necrosis factor-alpha (TNF-alpha), H. pylori infection, and susceptibility to gastrointestinal disorders
Ying-Jun Chang et al.
Journal of clinical immunology, 29(5), 696-704 (2009-05-23)
The aim of this study was to investigate the association of donor CD4(+) T cells expressing CD62L with transplant outcomes. We report a prospective analysis of 31 patients who were treated with a Bu/Cy regimen, followed by unmanipulated blood and
Eva-Katrin Bentz et al.
Reproductive sciences (Thousand Oaks, Calif.), 14(7), 705-709 (2007-11-15)
The relation between genetic variation of the androgen metabolism and transsexualism is unknown. In a case-control study of 100 male-to-female (MtF) transsexuals, 47 female-to-male (FtM) transsexuals, and 1670 controls, the authors assess allele and genotype frequencies of the steroid 5-alpha
Ken-Pen Weng et al.
Circulation journal : official journal of the Japanese Circulation Society, 74(3), 544-551 (2010-01-19)
Approximately 8-38% of children with Kawasaki disease (KD) will have persistent or recrudescent fever after initial intravenous immunoglobulin (IVIG) treatment and are at increased risk for development of coronary artery abnormalities. Using genetic markers may be helpful to identify the
Wanli Lu et al.
Carcinogenesis, 26(3), 631-636 (2004-12-08)
Helicobacter pylori infection and the cytokine-mediated inflammatory responses play important roles in gastric cancer pathogenesis. This case control study was conducted to assess the association between genetic polymorphisms in interleukin (IL)-1B, IL-1RN, IL-8, IL-10 and tumor necrosis factor alpha (TNFalpha)
Shu-Pin Huang et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 13(12), 2217-2224 (2004-12-16)
The tumor suppressor gene p53 and its downstream effector p21 are thought to play major roles in the development of human malignancy. Polymorphic variants of p53 at codon 72, and p21 at codon 31, have been found to be associated
Fred Saad et al.
The Lancet. Oncology, 16(3), 338-348 (2015-02-24)
Orteronel is an investigational, partially selective inhibitor of CYP 17,20-lyase in the androgen signalling pathway, a validated therapeutic target for metastatic castration-resistant prostate cancer. We assessed orteronel in chemotherapy-naive patients with metastatic castration-resistant prostate cancer. In this phase 3, double-blind
F Neunhoeffer et al.
Klinische Padiatrie, 227(2), 66-71 (2015-02-05)
For quick detection of neonatal early-onset bacterial infection (EOBI) pro-inflammatory cytokines like Interleukin-6 (IL-6) and Interleukin-8 (IL-8) in combiantion with C-reactive Protein (CRP) have been used. Automated determination of immature myeloid information (IMI) seems to be an additional useful tool
Koichiro Yamakado et al.
International journal of clinical oncology, 19(5), 955-962 (2013-11-30)
The aim of this study was to evaluate the safety and clinical utility of radiofrequency ablation (RFA) retrospectively in non-surgical candidates with recurrent bone and soft-tissue sarcomas. Percutaneous RFA was used in 52 patients (21 female, 31 male; mean age
Valérie Bonadona et al.
JAMA, 305(22), 2304-2310 (2011-06-07)
Providing accurate estimates of cancer risks is a major challenge in the clinical management of Lynch syndrome. To estimate the age-specific cumulative risks of developing various tumors using a large series of families with mutations of the MLH1, MSH2, and
Elvira Garza-González et al.
Revista de gastroenterologia de Mexico, 68(2), 107-112 (2004-05-07)
Interleukin-10, tumor necrosis factor alpha, Interleukin-1 beta and interleukin-1 receptor antagonist cytokines modulate the inflammatory response in presence of Helicobacter pylori. Pro-inflammatory interleukin 10 (IL-10-592, -1082), TNF alpha (TNF alpha-308), interleukin-1 beta and interleukin-1 receptor antagonist (IL-1B-31*C and IL-1RN*2/*2) genotypes
S H Ibbotson et al.
The British journal of dermatology, 166(2), 380-388 (2011-10-05)
There is marked interpatient variation in responses to psoralen-ultraviolet A (PUVA) photochemotherapy. Identification of molecular biomarkers of PUVA sensitivity may facilitate treatment predictability.The glutathione S-transferases (GSTs) influence cutaneous defence against UV radiation-induced oxidative stress and are therefore candidate biomarkers of
Alexander A Leung et al.
The Canadian journal of cardiology, 29(12), 1616-1622 (2013-11-26)
Previous research suggests that the early benefit from revascularization with drug-eluting stents might diminish over time. We performed an extended analysis of a previously identified cohort of 6440 patients who underwent percutaneous coronary intervention between April 1, 2003 and March
Paulette Mhawech-Fauceglia et al.
American journal of clinical pathology, 133(6), 899-908 (2010-05-18)
Differentiating uterine serous carcinoma (USC) from endometrioid adenocarcinoma (EAC) could be problematic, especially in high-grade EACs and tumors exhibiting architectural variations. To address this issue, we evaluated 103 endometrial carcinoma cases using 4 immunomarkers, beta-catenin, IMP3, PTEN, and p53. Cases
Emily R Adams et al.
Wellcome open research, 5, 139-139 (2021-03-23)
Background: The COVID-19 pandemic caused >1 million infections during January-March 2020. There is an urgent need for reliable antibody detection approaches to support diagnosis, vaccine development, safe release of individuals from quarantine, and population lock-down exit strategies. We set out
Marzia Lazzerini et al.
JAMA, 310(20), 2164-2173 (2013-11-28)
Pediatric-onset Crohn disease is more aggressive than adult-onset disease, has high rates of resistance to existing drugs, and can lead to permanent impairments. Few trials have evaluated new drugs for refractory Crohn disease in children. To determine whether thalidomide is
Jin-Ha Yoon et al.
PloS one, 10(3), e0119731-e0119731 (2015-03-26)
This study aimed to assess the association between oxidative damage markers and carotid artery intima-media thickness (CIMT) after controlling for conventional risk factors of atherosclerosis in multiple logistic regression models. Fifty-one case male participants (CIMT ≥ 0.9 mm) were enrolled
Duk-Woo Park et al.
JAMA, 312(19), 2019-2027 (2014-11-17)
Little information exists about the anatomical characteristics and clinical relevance of non-infarct-related artery (IRA) disease among patients with ST-segment elevation myocardial infarction (STEMI). To investigate the incidence, extent, and location of obstructive non-IRA disease and compare 30-day mortality according to
Johannes A N Dorresteijn et al.
Journal of hypertension, 31(2), 393-403 (2012-12-14)
The objective of this study is to determine the effects of renin-angiotensin-aldosterone system inhibition, sympathoinhibition and diuretic therapy on endothelial function and blood pressure in obesity-related hypertension. A randomized, four-way, double-blind, crossover study in 31 adults with previously untreated obesity-related
Carmela Gurrieri et al.
Journal of the National Cancer Institute, 96(4), 269-279 (2004-02-19)
The PML gene is fused to the RARalpha gene in the vast majority of acute promyelocytic leukemias (APL) and has been implicated in the control of key tumor-suppressive pathways. However, its role in the pathogenesis of human cancers other than
Michelle Furtado et al.
British journal of haematology, 168(1), 55-62 (2014-08-26)
The proteasome inhibitor, bortezomib, potentially increases cell sensitivity to chemotherapy. This study was performed to determine the overall response rate (ORR), overall survival (OS), progression-free survival (PFS) and toxicity of CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) compared to CHOP +
Dominiek D G Despriet et al.
JAMA, 296(3), 301-309 (2006-07-20)
The evidence that inflammation is an important pathway in age-related macular degeneration (AMD) is growing. Recent case-control studies demonstrated an association between the complement factor H (CFH) gene, a regulator of complement, and AMD. To assess the associations between the
Cathie Sudlow et al.
Stroke, 37(2), 364-370 (2005-12-31)
Apolipoprotein E genotype (APOE) is associated with cholesterol metabolism, ischemic heart disease, and cerebral amyloid angiopathy, and so may affect risk of both ischemic and hemorrhagic stroke. We comprehensively sought and identified studies of the association of apoE with ischemic
V Vaccaro et al.
BioMed research international, 2014, 351252-351252 (2014-05-31)
No established chemotherapeutic regimen exists for the treatment of recurrent malignant gliomas (rMGs). Herein, we report the activity and safety results of the bevacizumab (B) plus fotemustine (FTM) combination for the treatment of rMGs. An induction phase consisted of B
Martin R Stockler et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(13), 1309-1316 (2014-04-02)
To determine the effects of bevacizumab on patient-reported outcomes (PROs; secondary end point) in the AURELIA trial. Patients with platinum-resistant ovarian cancer were randomly assigned to chemotherapy alone (CT) or with bevacizumab (BEV-CT). PROs were assessed using the European Organisation
Osseointegrated hearing implant surgery using a novel hydroxyapatite-coated concave abutment design.
Mark D Wilkie et al.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 151(6), 1014-1019 (2014-09-24)
Recently, a novel hydroxyapatite-coated concave bone-anchored hearing device abutment was introduced, the first designed specifically to improve outcomes in soft-tissue preservation osseointegrated hearing implant surgery. We sought to evaluate our early experience with this abutment. A single-center case series with
E Vergnaud et al.
British journal of anaesthesia, 114(1), 103-109 (2014-10-16)
Postoperative fluid management can be challenging in children after haemorrhagic surgery. The goal of this study was to assess the ability of dynamic cardiovascular variables measured using bioreactance (NICOM®, Cheetah Medical, Tel Aviv, Israel) to predict fluid responsiveness in postoperative
Andrés J M Ferreri et al.
Neurology, 82(15), 1370-1373 (2014-03-19)
We report updated results at a median follow-up of 12 years of a phase II trial assessing first-line MATILDE chemotherapy and response-tailored radiotherapy in patients with primary CNS lymphomas (PCNSL). Forty-one HIV-negative patients (18-70 years; Eastern Cooperative Oncology Group performance
R P Moody et al.
Journal of toxicology and environmental health, 20(1-2), 209-218 (1987-01-01)
The dermal penetration of 14C-ring-labeled fenitrothion and aminocarb was determined in rats and rhesus monkeys. In monkeys, 49 +/- 4% (t1/2 = 14 h) of the fenitrothion and 74 +/- 4% (t1/2 = 25 h) of aminocarb were absorbed from
S F Paul Man et al.
Therapeutic advances in respiratory disease, 3(2), 73-80 (2009-05-26)
Several studies suggest that inhaled and oral corticosteroids repress systemic inflammation in chronic obstructive pulmonary disease (COPD). However, the cytokines that may respond to these medications are unclear. We used data from 41 patients with a history of stable moderate
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