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显示 31-60 共 273 条结果 关于 "95-31-8" 范围 论文
Wanqiu Zhu et al.
Medicine, 95(46), e5202-e5202 (2016-11-20)
Renal insufficiency is a common and severe complication of patients with multiple myeloma. The aim of this study was to evaluate bortezomib-based treatment for multiple myeloma patients with renal insufficiency. The Cochrane Library, Embase, PubMed, ISI, China National Knowledge Infrastructure
Nazir Ahmed Ismail et al.
The Lancet. Infectious diseases, 18(7), 779-787 (2018-04-25)
Globally, per-capita, South Africa reports a disproportionately high number of cases of multidrug-resistant (MDR) tuberculosis and extensively drug-resistant (XDR) tuberculosis. We sought to estimate the prevalence of resistance to tuberculosis drugs in newly diagnosed and retreated patients with tuberculosis provincially
Allen L Cohn et al.
Clinical colorectal cancer, 10(3), 171-177 (2011-08-23)
This prospective analysis evaluated the effect of tumor KRAS status on efficacy of second-line panitumumab plus folinic acid/5-fluorouracil/irinotecan (FOLFIRI). This phase 2, open-label, single-arm study enrolled patients with unresectable, measurable metastatic colorectal cancer (mCRC) after failure of first-line treatment with
Vishal Sondhi et al.
Journal of pediatric hematology/oncology, 35(7), 493-499 (2013-08-10)
Propranolol has emerged as front-line therapy for infantile hemangiomas (IHs). However, a well-defined protocol for administering and predicting response to propranolol is unavailable. In this open-label trial, 31 children with IH (median age=5 mo; range,1 mo to 9 y) were
M Matejková-Behanová et al.
Physiological research, 53(2), 187-190 (2004-03-30)
Variability in the number of tandem repeats of the insulin gene (INS VNTR) is probably involved in the genetic regulation of insulin secretion. The aim of this study was to investigate the association of INS VNTR polymorphism with the presence
Raissa Santos et al.
The American journal of drug and alcohol abuse, 41(5), 433-441 (2015-07-15)
Nightclubs are favorable environments for alcohol abuse and the use of other drugs among patrons. To identify patterns of alcohol use in a high-risk population and their relationship with sociodemographic factors and illicit drug use. A portal survey technique was
C A Faaland et al.
Biochimica et biophysica acta, 1442(2-3), 353-360 (1998-11-07)
Nucleobase transport is important for the metabolism of nucleic acids and antiviral and antineoplastic drugs. This transport has been functionally described in several mammalian cells but has not been well characterized molecularly. We report the cloning of two novel transporters.
Tilakavati Karupaiah et al.
Scientific reports, 9(1), 13666-13666 (2019-09-22)
We conducted this cross-sectional population study with a healthy multi-ethnic urban population (n = 577) in Malaysia, combining nutritional assessments with cardiometabolic biomarkers defined by lipid, atherogenic lipoproteins, inflammation and insulin resistance. We found diametrically opposing associations of carbohydrate (246·6 ± 57·7 g, 54·3 ± 6·5%-TEI) and
Pietro Manuel Ferraro et al.
The American journal of clinical nutrition, 100(6), 1596-1603 (2014-11-21)
Although caffeine intake may increase urine calcium excretion, caffeine-containing beverages have been associated with a lower risk of nephrolithiasis. We sought to determine the association between caffeine intake and the risk of incident kidney stones in 3 large prospective cohorts.
Ida Martinelli et al.
Archives of internal medicine, 163(22), 2771-2774 (2003-12-10)
Conflicting data are available on air travel as a risk factor for venous thromboembolism. To our knowledge, there are no studies investigating whether individuals with thrombophilia and those taking oral contraceptives are more likely to develop venous thromboembolism during flights
Amar Safdar et al.
Acta haematologica, 131(1), 50-58 (2013-09-21)
Despite limited evidence for efficacy, granulocyte transfusions (GTX) are used to prevent and treat opportunistic infections in patients with neutropenia. Three hundred and seventy-three GTX given to 74 patients were assessed retrospectively. GTX were discontinued because of clinical improvement more
Heimo H Wenzl et al.
Digestive diseases and sciences, 60(5), 1414-1423 (2014-11-09)
Many patients with quiescent Crohn's disease are maintained on long-term treatment with azathioprine (AZA), but controlled data are limited. We aimed to evaluate the efficacy of AZA therapy for more than 4 years to maintain clinical remission. We performed a
Yu Zhang et al.
JAMA network open, 3(4), e202159-e202159 (2020-04-08)
Although phthalate exposure during pregnancy has been associated with preterm birth, the association of preconception exposure in either parent with preterm birth constitutes a knowledge gap. To examine the association of paternal and maternal preconception urinary concentrations of biomarkers of
Masanori Noguchi et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 22(1), 54-60 (2015-11-20)
The prognosis of platinum-based chemotherapy-resistant metastatic urothelial cancer of the bladder remains poor. Personalized selection of the right peptides for each patient could be a novel approach for a cancer vaccine to boost anticancer immunity. In this randomized, open-label, phase
Miroslav Djokic et al.
Haematologica, 94(7), 1016-1019 (2009-05-21)
We evaluated CD123 expression in 95 pediatric and 24 adult ALL patients and compared the results with the CD123 expression in normal B-cell precursors. Early B-cell precursors were negative while intermediate precursors and mature B cells showed weak CD123 expression.
Gordon Cook et al.
The Lancet. Haematology, 3(7), e340-e351 (2016-07-05)
The Myeloma X trial previously reported improved durability of response (time to disease progression) in patients with relapsed multiple myeloma with salvage autologous stem-cell transplantation (ASCT) compared with oral cyclophosphamide in patients with multiple myeloma relapsing after a first ASCT.
Jaime Soto et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 56(9), 1255-1260 (2013-02-08)
Cutaneous leishmaniasis is an ultimately self-curing disease for which systemic therapy with pentavalent antimony (Sb) is effective but with side effects. We evaluated 2 local treatments, intralesional (IL) Sb and cryotherapy, for single lesions due to Bolivian Leishmania (v.) braziliensis
M H Roozeboom et al.
The British journal of dermatology, 172(3), 739-745 (2014-07-30)
A recent noninferiority randomized controlled trial (RCT) indicated that imiquimod can be considered as superior to methylaminolevulinate photodynamic therapy (MAL-PDT) in the treatment of superficial basal cell carcinoma (sBCC). Knowledge of treatment effectiveness in subgroups of patients is of great
Glen J Weiss et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2(10), 933-938 (2007-10-03)
This multicenter, phase II clinical trial was conducted to evaluate the activity of the combination of docetaxel and exisulind in advanced non-small cell lung cancer (NSCLC) patients who failed a prior platinum-containing regimen. Patients with measurable disease and adequate organ
W-M Cai et al.
The pharmacogenomics journal, 6(5), 343-350 (2006-03-22)
Limited information is available on the frequency of the many CYP2D6 alleles found in African-Americans. DNA was isolated and genetic testing was performed on samples from 222 African-Americans, healthy controls (n=131), and psychiatric patients (n=91). Each DNA was tested for
Michaela B Kirschner et al.
Molecular oncology, 9(3), 715-726 (2014-12-17)
Prognosis of malignant pleural mesothelioma (MPM) is poor, and predicting the outcomes of treatment is difficult. Here we investigate the potential of microRNA expression to estimate prognosis of MPM patients. Candidate microRNAs from microarray profiling of tumor samples from 8
Erminia Massarelli et al.
JAMA oncology, 5(1), 67-73 (2018-09-30)
In recurrent human papilloma virus (HPV)-driven cancer, immune checkpoint blockade with anti-programmed cell death 1 (PD-1) antibodies produces tumor regression in only a minority of patients. Therapeutic HPV vaccines have produced strong immune responses to HPV-16, but vaccination alone has
Marsha A Raebel et al.
JAMA, 310(13), 1369-1376 (2013-10-03)
Obesity is associated with chronic noncancer pain. It is not known if opioid use for chronic pain in obese individuals undergoing bariatric surgery is reduced. To determine opioid use following bariatric surgery in patients using opioids chronically for pain control
Dinesh Shrikrishna et al.
Chest, 146(4), 932-940 (2014-02-22)
Skeletal muscle impairment is a recognized complication of COPD, predicting mortality in severe disease. Increasing evidence implicates the renin-angiotensin system in control of muscle phenotype. We hypothesized that angiotensin-converting enzyme (ACE) inhibition would improve quadriceps function and exercise performance in
Kuanfeng Xu et al.
Diabetes research and clinical practice, 91(2), 195-202 (2010-12-07)
To investigate the association of solute carrier family 30 member 8 (SLC30A8) rs13266634 C/T polymorphism with type 2 diabetes (T2DM), impaired glucose tolerance (IGT), and type 1 diabetes (T1DM). We searched all the publications about the association between SLC30A8 and
Joanne Ryan et al.
Psychoneuroendocrinology, 36(10), 1582-1586 (2011-05-17)
Estrogen is thought to play a key role in anxiety, but it remains unknown whether genetic variants in the estrogen receptors (ERs) can influence the risk of anxiety. This study investigated whether ESR1 and ESR2 gene variants were associated with
D Abebe et al.
Letters in applied microbiology, 61(5), 469-476 (2015-08-19)
Corynebacterium pseudotuberculosis is the causative agent of caseous lymphadenitis, a suppurative abscessation in the superficial and internal lymph nodes and internal organs of small ruminants. This study was conducted on the superficial lymph nodes and carcasses of 768 small ruminants
Amelia Szymanowska et al.
Lung cancer (Amsterdam, Netherlands), 52(1), 9-14 (2006-02-28)
The aim of this study was to assess whether the TP53 Arg72Pro polymorphism is associated with an increased risk of non-small cell lung cancer (NSCLC). Additionally, in NSCLC patients, we investigated a potential association between this polymorphism and somatic TP53
C R Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(7), 2784-2788 (1993-04-01)
H-2M3 encodes HMT, the major histocompatibility complex (MHC) class I heavy chain of the maternally transmitted antigen (Mta). Like classical MHC class I genes, the expression of M3 can be stimulated by gamma-interferon and its message can be detected from
Cristina Joana Marques et al.
Lancet (London, England), 363(9422), 1700-1702 (2004-05-26)
The possibility of imprinting disease transmission by assisted reproductive technologies has been raised after births of children with Angelman's and Beckwith-Wiedemann's syndromes. To investigate whether imprinting defects were associated with disturbed spermatogenesis, we studied two oppositely imprinted genes in spermatozoan
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