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显示 1-30 共 217 条结果 关于 "95-53-4" 范围 论文
Wei Nie et al.
Gene, 520(1), 22-29 (2013-03-05)
A number of studies assessed the association of -589C/T polymorphism in the promoter region of interleukin-4 (IL-4) with asthma in different populations. However, the results were contradictory. A meta-analysis was conducted to investigate the association between polymorphism in the IL-4
Isabel Martínez-Gras et al.
European archives of psychiatry and clinical neuroscience, 256(7), 437-441 (2006-06-22)
The cannabinoid receptor 1 gene (CNR1) has been associated with addictive disorders and schizophrenia in different studies. We have compared the frequencies of the alleles for the 3'-UTR CNR1 microsatellite in a sample of 113 Spanish schizophrenic patients, including 68
A Jackson et al.
British journal of haematology, 111(2), 562-564 (2000-12-21)
Allele frequencies for the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene were determined in a large case-control study of 517 unselected patients with venous thromboembolism and 478 blood donors. The D allele frequency was 0. 53 [95% confidence
Gabriel Carrasquilla et al.
The American journal of tropical medicine and hygiene, 86(1), 75-83 (2012-01-11)
The safety of artemether-lumefantrine in patients with acute, uncomplicated Plasmodium falciparum malaria was investigated prospectively using the auditory brainstem response (ABR) and pure-tone thresholds. Secondary outcomes included polymerase chain reaction-corrected cure rates. Patients were randomly assigned in a 3:1:1 ratio
Luca Gianotti et al.
Annals of surgery, 267(4), 623-630 (2017-06-06)
To explore whether preoperative oral carbohydrate (CHO) loading could achieve a reduction in the occurrence of postoperative infections. Hyperglycemia may increase the risk of infection. Preoperative CHO loading can achieve postoperative glycemic control. This was a randomized, controlled, multicenter, open-label
H Scheinin et al.
The Journal of antimicrobial chemotherapy, 34(5), 813-817 (1994-11-01)
We compared aspoxicillin, a new broad-spectrum penicillin derivative, with piperacillin in severe abdominal infection. Aspoxicillin 4 g administered tds (n = 52) or piperacillin 4 g qds (n = 53) usually as monotherapy were randomly given to patients suffering from
Tarayn Fairlie et al.
Obstetrics and gynecology, 121(3), 570-577 (2013-05-03)
To estimate the effectiveness against early-onset group B streptococcal (GBS) disease of intrapartum antibiotic prophylaxis among term and preterm deliveries, deliveries with fewer than 4 hours of antibiotics, and deliveries receiving clindamycin regimens. We performed a secondary analysis of the
Hua Zhao et al.
Molecular carcinogenesis, 33(2), 99-104 (2002-01-29)
Microsomal epoxide hydrolase (mEPHX) is a critical metabolic enzyme involved in the activation and subsequent detoxification of specific tobacco carcinogens. mEPHX harbors polymorphisms in exon 3 and exon 4 that modulate enzymatic activity. The exon 3 polymorphism decreases mEPHX metabolic
Y Blanco et al.
Revista de neurologia, 53(3), 146-152 (2011-07-13)
The existence of antibodies to aquaporin-4 (AQP-4-ab) has identified neuromyelitis optica (NMO) and multiple sclerosis (MS) as different diseases. Although HLA-DRB1 alleles contribute to MS risk, recent studies suggest that HLA back-ground differs between patients with NMO or MS in
Takara L Stanley et al.
JAMA, 312(4), 380-389 (2014-07-20)
Among patients infected with human immunodeficiency virus (HIV), visceral adiposity is associated with metabolic dysregulation and ectopic fat accumulation. Tesamorelin, a growth hormone-releasing hormone analog, specifically targets visceral fat reduction but its effects on liver fat are unknown. To investigate
Maria Belen Roldan Martin et al.
Fertility and sterility, 82(5), 1460-1462 (2004-11-10)
To determine if variants in the melanocortin-4 receptor (MC4R) gene are associated with premature pubarche (PP) in children and hyperandrogenism (HA) in adolescent girls, we performed single-strand conformational polymorphism (SSCP) in 75 children (69 girls/six boys) with PP, 53 adolescent
Patrick Danoy et al.
PLoS genetics, 6(12), e1001195-e1001195 (2010-12-15)
Ankylosing spondylitis (AS) is a common inflammatory arthritic condition. Overt inflammatory bowel disease (IBD) occurs in about 10% of AS patients, and in addition 70% of AS cases may have subclinical terminal ileitis. Spondyloarthritis is also common in IBD patients.
Petros Christopoulos et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 18(9), 1430-1437 (2012-03-21)
Total body irradiation has been the mainstay of conditioning since the inception of allogeneic hematopoietic cell transplantation, but toxicity often precludes its use. For less-fit patients with acute lymphoblastic leukemia and other hematologic malignancies frequently affecting the central nervous system
Amandine Le Bourgeois et al.
Experimental hematology, 42(11), 945-954 (2014-07-30)
Our main objective was to determine new factors associated with engraftment and single-unit predominance after double umbilical cord blood (UCB) allogeneic stem-cell transplantation. Engraftment occurred in 78% of cases in this retrospective study including 77 adult patients. Three-year overall survival
Júlia Faura et al.
Journal of Alzheimer's disease : JAD, 73(4), 1585-1595 (2020-01-21)
CCL23 is a chemokine implicated in inflammation and host defense responses. It has been recently associated with acquired brain damage and stroke outcomes. In this study, we reported the role of CCL23 in Alzheimer's disease (AD). We evaluated the levels
Felicitas Thol et al.
Haematologica, 95(10), 1668-1674 (2010-05-25)
Myelodysplastic syndromes are a heterogeneous group of hematopoietic stem cell disorders with a high propensity to transform into acute myeloid leukemia. Heterozygous missense mutations in IDH1 at position R132 and in IDH2 at positions R140 and R172 have recently been
J Hernesniemi et al.
Scandinavian journal of clinical and laboratory investigation, 66(8), 667-675 (2006-11-15)
Atherosclerosis is considered to be a chronic inflammatory disease. Toll-like receptor 4 (TLR-4), a key mediator in activating inflammatory cascade, has an A-to-G functional polymorphism that changes aspartic acid to glycine at position 299. TLR-4 is activated by, for example
Y H Lee et al.
Lupus, 13(3), 188-191 (2004-05-04)
The objective was to investigate whether the functional polymorphism of intron 4 in the endothelial nitric oxide synthase (eNOS) gene is associated with susceptibility to systemic lupus erythematosus (SLE) and its clinical features. The 27-bp repeat polymorphism in intron 4
Massimo Imazio et al.
Circulation, 123(10), 1092-1097 (2011-03-02)
The role of inflammatory markers is not well defined for either diagnosis or treatment of pericarditis. The aim of this study is to prospectively evaluate the frequency of high-sensitivity C-reactive protein (hs-CRP) elevation in patients with acute pericarditis, its time
Jocasta Ball et al.
Heart (British Cardiac Society), 99(8), 542-547 (2013-01-15)
We examined cognitive function in older hospitalised patients with chronic atrial fibrillation (AF). A prospective substudy of a multicentre randomised trial of an AF-specific disease management intervention (the Standard versus Atrial Fibrillation spEcific managemenT studY; SAFETY). Three tertiary referral hospitals
L-L Hsieh et al.
British journal of cancer, 92(1), 30-35 (2004-12-08)
The present study was designed to examine whether different p53 haplotypes of exon 4-intron 3-intron 6 affect the frequency of mutations and loss of heterozygosity (LOH) of the p53 gene in male oral squamous cell carcinomas (OSCCs) in Taiwan. We
E Goekkurt et al.
Annals of oncology : official journal of the European Society for Medical Oncology, 20(3), 481-485 (2008-12-17)
Docetaxel-based chemotherapy regimens have demonstrated activity in advanced gastric cancer (AGC). However, a high rate of grade 3/4 hematotoxicity was reported with these regimens. Our purpose was to identify pharmacogenetic markers with potential to detect patients with increased risk to
Anick Bérard et al.
Headache, 52(7), 1085-1093 (2012-05-23)
Dihydroergotamine (DHE) is perceived to be associated with a higher risk of adverse pregnancy events, but it has significantly less vasoconstrictive and uterotonic effects compared with ergotamine, and has demonstrated no teratogenic effect in animals. The objectives of this study
Flora Tassone et al.
Autism research : official journal of the International Society for Autism Research, 4(4), 250-261 (2011-05-04)
Genetic factors are established to contribute to the development of autism. We examined three loci, serotonin transporter (SLC6A4), dopamine β-hydroxylase (DBH), and the variable number of tandem repeat promoter of the monoamine oxidase A (MAOA) for association with autism in
F Chiadmi et al.
Journal of clinical pharmacy and therapeutics, 30(3), 255-258 (2005-05-18)
To assess the stability of doxorubicin combined with Radioselectan. Solutions of doxorubicin 5 mg/mL were prepared from commercially available 50 mg powder with 10 mL of Radioselectan. They were stored in glass syringes at 4, 25 and 45 degrees C.
Akira Tsuburaya et al.
The Lancet. Oncology, 15(8), 886-893 (2014-06-24)
The prognosis for locally advanced gastric cancer is poor despite advances in adjuvant chemotherapy. We did the Stomach cancer Adjuvant Multi-Institutional group Trial (SAMIT) to assess the superiority of sequential treatment (paclitaxel then tegafur and uracil [UFT] or paclitaxel then
Benjamin M Scirica et al.
The New England journal of medicine, 369(14), 1317-1326 (2013-09-03)
The cardiovascular safety and efficacy of many current antihyperglycemic agents, including saxagliptin, a dipeptidyl peptidase 4 (DPP-4) inhibitor, are unclear. We randomly assigned 16,492 patients with type 2 diabetes who had a history of, or were at risk for, cardiovascular
Yongliang Jia et al.
International journal of cardiology, 157(3), 330-340 (2011-01-22)
Danshen dripping pill (DSP) is a popular Chinese medicinal product and often compared with isosorbide dinitrate (ISDN) in treating coronary heart disease angina pectoris. Over 100 randomized controlled trials (RCT) have been published in Chinese language but have not been
Masahiro Nozawa et al.
World journal of urology, 33(9), 1263-1268 (2014-10-31)
This study evaluated the baseline patient characteristics associated with the time to biochemical progression and overall survival in patients who participated in a phase II trial on zoledronic acid combined with the initial androgen-deprivation therapy for treatment-naïve bone-metastatic prostate cancer.
Vahid Zadmajid et al.
Animal reproduction science, 187, 79-90 (2017-11-09)
Knowledge of gamete quality is a prerequisite for developing techniques to fertilize eggs and rear offspring for hatchery production. Our objective was to develop assisted reproductive techniques, via hormonal induction of final oocyte maturation (FOM), for Longspine scraper, Capoeta trutta.
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