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Alessandra Romano et al.
British journal of haematology, 168(5), 689-700 (2014-11-08)
In the attempt to find a peripheral blood biological marker that could mirror the dysregulated microenvironment of Hodgkin Lymphoma (HL), we analysed the amount of myeloid-derived suppressor cells (MDSC), including the three main sub-types (monocytic, granulocytic and CD34 + fraction).
Peter Helmbold et al.
Molecular carcinogenesis, 48(10), 903-909 (2009-03-28)
Merkel cell carcinoma (MCC) is one of the most aggressive cancers of the skin. It has recently been reported that integration of a Merkel cell polyomavirus (MCPyV) in receptor tyrosine phosphates type G (PTPRG) gene occurs in MCC, and that
Fiona V Cresswell et al.
The Lancet. Infectious diseases, 20(3), 308-317 (2020-01-12)
Tuberculous meningitis accounts for 1-5% of tuberculosis cases. Diagnostic delay contributes to poor outcomes. We evaluated the performance of the new Xpert MTB/RIF Ultra (Xpert Ultra) for tuberculous meningitis diagnosis. In this prospective validation study, we tested the cerebrospinal fluid
Miriam H Inoue et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 44(8), 757-763 (2010-02-26)
This research was aimed at understanding the dynamics of the herbicides diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea], imazapic [2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-5-methylnicotinic acid] and isoxaflutole [5-cyclopropyl-4-(2-methanesulfonyl-4-trifluoromethyl benzoyl)isoxazole] in two soils of different physico-chemical properties. To accomplish such intent, several greenhouse experiments were run. The bioavailability of diuron
Farhad Mehrkhani et al.
Journal of neuroimaging : official journal of the American Society of Neuroimaging, 28(5), 524-529 (2018-05-12)
Imaging may identify patients with very large infarcts who are unlikely to benefit from intra-arterial therapy. Although computed tomography (CT) is widely used, it suffers from poor sensitivity. We sought to evaluate whether combined evaluation of noncontrast CT (NCCT) and
Yijun Kang et al.
The British journal of nutrition, 118(6), 431-440 (2017-10-06)
Anaemia during pregnancy, characterised by Hb <110 g/l, is a specific risk factor for adverse maternal and perinatal outcomes in developing countries. The objective of this study was to determine the effectiveness of daily antenatal supplementation with multiple micronutrients (MMN)
Tobias Broger et al.
The Lancet. Infectious diseases, 19(8), 852-861 (2019-06-04)
Most tuberculosis-related deaths in people with HIV could be prevented with earlier diagnosis and treatment. The only commercially available tuberculosis point-of-care test (Alere Determine TB LAM Ag [AlereLAM]) has suboptimal sensitivity, which restricts its use in clinical practice. The novel
Bunyong Phakdeekitcharoen et al.
Clinical endocrinology, 74(2), 152-159 (2010-11-04)
In Conn's syndrome, hypokalaemia normally results from renal potassium loss because of the effect of excess aldosterone on Na(+) -K(+) -ATPase in principal cells. Little is known about the effect of aldosterone on cellular potassium redistribution in skeletal muscle. Our
Ajay Vora et al.
The Lancet. Oncology, 15(8), 809-818 (2014-06-14)
No randomised study has shown whether stratification of treatment by minimal residual disease (MRD) response improves outcome in children and young people with acute lymphoblastic leukaemia (ALL). We assessed whether children and young people with clinical standard and intermediate-risk ALL
Anu Suomalainen et al.
The Lancet. Neurology, 10(9), 806-818 (2011-08-09)
Muscle biopsy is the gold standard for diagnosis of mitochondrial disorders because of the lack of sensitive biomarkers in serum. Fibroblast growth factor 21 (FGF-21) is a growth factor with regulatory roles in lipid metabolism and the starvation response, and
Gerhard Binder et al.
Clinical endocrinology, 82(1), 100-105 (2014-09-11)
The distinction between constitutional delay of growth and puberty (CDGP) and isolated hypogonadotropic hypogonadism (IHH) in males with delayed puberty is difficult but important for timely treatment. We assessed the accuracy of the GnRH agonist test (triptorelin 0·1 mg) in
Alphonse Poklis et al.
Journal of analytical toxicology, 28(6), 422-425 (2004-11-02)
A study of the urinary concentration of fentanyl (F) and its major metabolite norfentanyl (NF) in chronic pain patients treated with the Duragesic continuous release transdermal patches is presented. These patches are available in 10, 20, 30, and 40 cm(2)
Masakazu Kobayashi et al.
Journal of vascular surgery, 69(2), 454-461 (2018-07-02)
The external carotid artery (ECA) is inadvertently occluded during carotid endarterectomy (CEA). The importance of ECA occlusion has been emphasized as a loss of extracranial to intracranial collaterals, a source of chronic embolization, or a site for extended thrombosis during
Dimitra Hadjipavlou-Litina et al.
Bioorganic & medicinal chemistry, 18(23), 8204-8217 (2010-11-03)
A series of symmetric and asymmetric spermine (SPM) conjugates with all-trans-retinoic acid (ATRA), acitretin (ACI), (E)-3-(trioxsalen-4'-yl)acrylic acid (TRAA) and L-DOPA, amides of ACI, l-DOPA and TRAA with 1-aminobutane, benzylamine, dopamine and 1,12-diaminobutane as well as hybrid conjugates of O,O'-dimethylcaffeic acid
Eva Bangels et al.
Communications in agricultural and applied biological sciences, 73(3), 655-658 (2009-02-21)
The codling moth is an economically important top fruit pest, with its major flight from May till August. We give an overview of ten years of results of efficacy field trials against the codling moth Cydia pomonella, with a number
Kwok Chiu Chang et al.
Antimicrobial agents and chemotherapy, 55(10), 4499-4505 (2011-07-20)
Standard culture-based testing of the susceptibility of Mycobacterium tuberculosis to pyrazinamide is difficult to perform. This systematic review with meta-analyses evaluated the roles of molecular assays targeting pncA and of pyrazinamidase assays. PubMed and Embase were searched for relevant publications
Amit Khatri et al.
Clinical pharmacokinetics, 58(6), 805-814 (2018-12-24)
The objective of this study was to characterize the effects of risankizumab on the in vivo activity of cytochrome P450 (CYP) 1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A in psoriasis patients using a cocktail approach. Patients with moderate to severe chronic
Xavier Bobbia et al.
Scandinavian journal of trauma, resuscitation and emergency medicine, 23, 52-52 (2015-07-08)
The use of focused cardiac ultrasound (FoCUS) in a prehospital setting is recommended. Pocket ultrasound devices (PUDs) appear to be well suited to prehospital FoCUS. The main aim of our study was to evaluate the interpretability of echocardiography performed in
Bénédicte F Callens et al.
Microbial drug resistance (Larchmont, N.Y.), 19(2), 146-151 (2012-12-20)
Streptococcus suis (S. suis) has often been reported as an important swine pathogen and is considered as a new emerging zoonotic agent. Consequently, it is important to be informed on its susceptibility to antimicrobial agents. In the current study, the
J Horton
Parasitology, 121 Suppl, S113-S132 (2001-06-02)
This comprehensive review briefly describes the history and pharmacology of albendazole as an anthelminthic drug and presents detailed summaries of the efficacy and safety of albendazole's use as an anthelminthic in humans. Cure rates and 0% egg reduction rates are
Yi-Bin Chen et al.
Cancer, 121(2), 226-233 (2014-09-11)
High-dose thiotepa, busulfan, and cyclophosphamide (TBC) with autologous stem cell transplantation (ASCT) has been used in patients with central nervous system (CNS) involvement by non-Hodgkin lymphoma (NHL). Despite limited penetration into the CNS, rituximab is active in primary CNS NHL.
L Guo et al.
Journal of applied microbiology, 119(1), 55-64 (2015-04-08)
The study aims to demonstrate the antimicrobial and disinfectant resistance phenotypes and genotypes of Escherichia coli isolates obtained from giant pandas (Ailuropoda melanoleuca). Antimicrobial testing was performed according to the standard disk diffusion method. The minimal inhibitory concentrations (MICs) of
Ajay Vora et al.
The Lancet. Oncology, 14(3), 199-209 (2013-02-12)
Minimal residual disease (MRD) is the most sensitive and specific predictor of relapse risk in children with acute lymphoblastic leukaemia (ALL) during remission. We assessed whether treatment intensity could be adjusted for children and young adults according to MRD risk
Alla Gabriella Wernicke et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 122(6), 482-489 (2013-12-07)
Prostate-specific membrane antigen (PSMA) has been found to be expressed in the tumor-associated neovasculature of multiple solid tumor types including breast cancers. However, thus far, the number of cases studied from some tumor types has been limited. In this study
Yanjun Zhang et al.
The Lancet. Infectious diseases, 21(2), 181-192 (2020-11-21)
With the unprecedented morbidity and mortality associated with the COVID-19 pandemic, a vaccine against COVID-19 is urgently needed. We investigated CoronaVac (Sinovac Life Sciences, Beijing, China), an inactivated vaccine candidate against COVID-19, containing inactivated severe acute respiratory syndrome coronavirus 2
Staging of neuroendocrine tumours: comparison of [⁶⁸Ga]DOTATOC multiphase PET/CT and whole-body MRI.
C Schraml et al.
Cancer imaging : the official publication of the International Cancer Imaging Society, 13, 63-72 (2013-03-08)
In patients with a neuroendocrine tumour (NET), the extent of disease strongly influences the outcome and multidisciplinary therapeutic management. Thus, systematic analysis of the diagnostic performance of the existing staging modalities is necessary. The aim of this study was to
B Branger et al.
Journal de gynecologie, obstetrique et biologie de la reproduction, 40(7), 657-667 (2011-09-24)
The aim of the study is to assess the compliance rate of treatment of postpartum hemorrhage (PPH) according to guidelines developed by the CNGOF within our network by a first audit, and evaluate the impact of this first audit by
Antje Timmer et al.
The Cochrane database of systematic reviews, 9(9), CD000478-CD000478 (2012-09-14)
Maintenance of remission is a major issue in inflammatory bowel disease. In ulcerative colitis, the evidence for the effectiveness of azathioprine and 6-mercaptopurine for the maintenance of remission is still controversial. To assess the effectiveness and safety of azathioprine and
National Toxicology Program technical report series, 487, 1-230 (2003-02-04)
Isobutene is produced during the fractionation of refinery gases or through the catalytic cracking of methyl-t-butyl ether. Isobutene is primarily used to produce diisobutylene, trimers, butyl rubber, and other polymers. In addition, it is used in the production of isooctane
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