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显示 1-30 共 437 条结果 关于 "99-10-5" 范围 论文
Tomasz Dylag et al.
Peptides, 29(3), 473-478 (2007-11-06)
Neuropeptide FF (NPFF) precursors from different species contain at least three known neuropeptides, i.e. FF (FLFQPQRF-NH(2)), AF (AGEGLSSPFWSLAAPQR-NH(2)) and SF (SLAAPQRF-NH(2)). We demonstrate that the rat NPFF precursor contains another bioactive sequence, NAWGPWSKEQLSPQA, spanning between positions 85 and 99. Synthetic
Oscar M Rodríguez-Narvaez et al.
Journal of environmental sciences (China), 93, 30-40 (2020-05-25)
Peroxymonosulfate (PMS) decomposition, hydroxyl radical (•OH) generation, and acetaminophen (ACT) degradation by the Co/PMS system using homogeneous (dissolved cobalt) and heterogeneous (suspended Co3O4) cobalt were assessed. For the homogeneous process, >99% PMS decomposition was observed and 10 mmol/L of •OH generation
Noa Ofer et al.
Nucleic acids research, 37(8), 2712-2722 (2009-03-11)
The 5' untranslated region of the FMR1 gene which normally includes 4-55 d(CGG) repeats expands to > 55-200 repeats in carriers of fragile X syndrome premutation. Although the levels of premutation FMR1 mRNA in carrier cells are 5-10-fold higher than
Hans-Joachim Gais et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 9(17), 4202-4221 (2003-09-04)
We describe the highly selective palladium catalyzed kinetic resolutions of the racemic cyclic allylic carbonates rac-1 a-c and racemic acyclic allylic carbonates rac-3 aa and rac-3 ba through reaction with tert-butylsulfinate, tolylsulfinate, phenylsulfinate anions and 2-pyrimidinethiol by using N,N'-(1R,2R)-1,2-cyclohexanediylbis[2-(diphenylphosphino)-benzamide] (BPA)
Carola Buccellati et al.
The Journal of pharmacology and experimental therapeutics, 317(2), 830-837 (2006-01-10)
Thromboxane (TX) A(2), prostacyclin (PGI(2)), and nitric oxide (NO) regulate platelet function and interaction with the vessel wall. Inhibition of TXA(2), implemented synthesis of PGI(2), and supply of exogenous NO may afford therapeutic benefit. 2NTX-99 [4-methoxy-N(1)-(4-trans-nitrooxycyclohexyl)-N(3)-(3-pyridinylmethyl)-1,3-benzenedicarboxamide], a new chemical entity
Zoltán Nemes et al.
The Journal of biological chemistry, 284(40), 27252-27264 (2009-08-05)
The alpha-synuclein immunopositive and chaotrope-insoluble material from human brains with Lewy body pathology was analyzed by mass spectrometry. From the proteinase K-cleavable peripheral fraction of Lewy bodies, which was densely cross-linked by gamma-glutamyl-epsilon-lysine bonds between HspB1 and ubiquitin in a
Gang Chen et al.
Organic letters, 10(20), 4573-4576 (2008-09-24)
A convenient and efficient synthesis of alpha-aryl nitriles was developed by direct cyanation of alcohols with TMSCN under the catalysis of Lewis acid. Using 5-10 mol % of InBr3 as the catalyst, a variety of benzylic alcohols can be converted
Xiaogen Huang et al.
Organic letters, 9(9), 1793-1795 (2007-04-03)
[reaction: see text] The enantioselective borane reduction of O-benzyloxime ethers to primary amines was studied under catalytic conditions using the spiroborate esters 5-10 derived from nonracemic 1,2-amino alcohols and ethylene glycol. Effective catalytic conditions were achieved using only 10% of
Ke Wang et al.
Anesthesia and analgesia, 123(6), 1603-1610 (2016-09-16)
Electroacupuncture (EA) is widely applied for pain management, but the analgesic effects of EA have not been fully elucidated. In this study, we investigated the effect of EA on inflammatory pain caused by intraplantar injection of complete Freund's adjuvant (CFA)
Sankha Chattopadhyay et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 66(10), 1295-1299 (2008-04-05)
Molybdenum-99 of low-to-medium specific activity, 7.4-14.8 GBq/g, obtained by the (98)Mo(n,gamma)(99)Mo reaction in research reactors requires a large alumina column to adsorb the molybdenum since the capacity of alumina to adsorb Mo is limited (20 mg Mo/g of alumina). The
Marina Villar et al.
Analytical and bioanalytical chemistry, 407(19), 5571-5578 (2015-05-27)
A new approach exploiting in-syringe dispersive liquid-liquid microextraction (DLLME) for (99)Tc extraction and preconcentration from biological samples, i.e., urine and saliva, and liquid residues from treated patients is presented. (99)Tc is a beta emitter with a long half-life (2.111 × 10(5) years)
Melissa A Fleegal et al.
American journal of physiology. Heart and circulatory physiology, 289(5), H2012-H2019 (2005-07-05)
The blood-brain barrier (BBB) is a metabolic and physiological barrier important for maintaining brain homeostasis. The aim of this study was to determine the role of PKC activation in BBB paracellular permeability changes induced by hypoxia and posthypoxic reoxygenation using
X Xing-Long et al.
Letters in applied microbiology, 56(5), 333-339 (2013-02-26)
Propidium monoazide is a DNA-intercalating dye. PMA-qPCR has been reported as a novel method to detect live bacteria in complex samples. In this study, this method was used to monitor the sterilization effects of UHP, ultrasound and high PEF on
Y Kubo
The Journal of physiology, 442, 691-710 (1991-10-01)
1. ATP was puff applied to cells of a mesodermal stem cell line, C3H10T1/2, and the responses were studied by whole-cell patch clamp recording. 2. In 91% of the cells (90/99), K+ current lasting for tens of seconds was observed
R Bruce David et al.
Molecular and cellular endocrinology, 188(1-2), 207-218 (2002-03-26)
A partial cDNA of the sheep erythropoietin receptor (EpoR) was obtained and used in real-time PCR to quantitate mRNA levels in placenta, liver and kidney throughout development (term=150 days). This was compared with Epo mRNA levels in the same tissues.
T Yoshimoto et al.
Biochemical and biophysical research communications, 116(2), 612-618 (1983-10-31)
Various flavonoids were found to be relatively selective inhibitors of arachidonate 5-lipoxygenase which initiates the biosynthesis of leukotrienes with the activity of slow reacting substance of anaphylaxis. Cirsiliol (3',4',5-trihydroxy-6,7-dimethoxyflavone) was most potent, and the enzyme partially purified from rat basophilic
Viktoria Winter et al.
Environmental toxicology and chemistry, 32(3), 562-568 (2012-12-22)
Based on a literature review of avian data for polybrominated diphenyl ethers (PBDEs), ecologically relevant doses, low (10 ng/egg), medium (100 ng/egg), and high (1,000 ng/egg) of the 2,2',4,4',5-pentabromodiphenyl ether (BDE-99) congener along with dimethylsulfoxide (DMSO) control were injected into the yolk sac
Monika Raj et al.
Organic letters, 8(18), 4097-4099 (2006-08-25)
We have demonstrated that a new class of l-proline-based organic compounds catalyzed the direct aldol reaction between aldehydes and acetone to provide beta-hydroxy ketones in good yields. The reaction is efficient, and 5-10 mol % of the catalyst and excellent
R B Cumming et al.
Biochemical genetics, 17(5-6), 415-431 (1979-06-01)
A single formamidase, which is different from the formamidases found in other tissues occurs in the brains of mice. This enzyme is here called formamidase-5 and the gene symbol is designated For-5. Two alleles are recognized on the basis of
Alireza Mirzaei et al.
Annals of nuclear medicine, 29(6), 506-511 (2015-04-24)
Optimized production and quality control of gallium-68 labeled ethylenediamine tetramethylene phosphonate ((68)Ga-EDTMP) as an efficient PET radiotracer for bone scans have been presented. Efforts have been made to present a fast, efficient, cost-effective and facile protocol for (68)Ga-EDTMP productions for
Gulcan Sahal et al.
Revista da Sociedade Brasileira de Medicina Tropical, 51(5), 644-650 (2018-10-12)
The increase in the incidence of fungal infections, especially those caused by Candida albicans and other Candida species, necessitates the understanding and treatment of Candida-associated infections. In this study, we aimed to investigate the identification, distribution, and biofilm formation ability
Martin H Fechter et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 13(12), 3369-3376 (2007-01-18)
3-Tetrahydrothiophenone (4) and 4-phenylthiobutan-2-one (7) were used as masked 2-butanone equivalents to give the corresponding cyanohydrins 5 (79 % yield, 91 % ee) and 8 (95 % yield, 96 % ee) in an enzymatic cyanohydrin reaction applying the hydroxynitrile lyase
Yafim Brodov et al.
Atherosclerosis, 238(1), 4-8 (2014-12-03)
The predictive value of thoracic aortic calcium (TAC) scores for coronary artery calcium (CAC) conversion (CAC>0) has not been fully evaluated. We studied 1648 asymptomatic subjects (mean age 52 ± 9 years, 54% male) with baseline CAC = 0 who underwent repeat CAC scanning
D Lio et al.
Genes and immunity, 3(1), 30-33 (2002-02-22)
Ageing is characterized by a pro-inflammatory status, which could contribute to the onset of major age-related diseases. Thus, genetic variations in pro- or anti-inflammatory cytokines might influence successful ageing and longevity. IL-10 is an appropriate candidate because it exerts powerful
Wancheng Zhu et al.
Inorganic chemistry, 51(11), 6020-6031 (2012-05-16)
(Ni(1-x),Mg(x))(3)Si(2)O(5)(OH)(4) solid-solution nanotubes (NTs) with tunable compositions were hydrothermally synthesized by altering the molar ratio of Mg(2+) to Ni(2+). The as-synthesized NTs were loaded with sub-0.06 wt % palladium (Pd; ∼0.045 wt %) for Suzuki-Miyaura (SM) coupling reactions between iodobenzene
M Auxiliadora Dea-Ayuela et al.
Bioorganic & medicinal chemistry, 17(21), 7449-7456 (2009-10-09)
A series of compounds containing the nitrobenzene and sulfonamido moieties were synthesized and their leishmanicidal effect was assessed in vitro against Leishmaniainfantum promastigotes. Among the compounds evaluated, the p-nitrobenzenesulfonamides 4Aa and 4Ba, and the p-nitroaniline 5 showed significant activity with
E U Sarmiento et al.
Journal of immunology (Baltimore, Md. : 1950), 155(4), 2211-2221 (1995-08-15)
We have examined the potential of IL-3, IL-5, and granulocyte-macrophage (GM)-CSF to enhance basophil activation by eosinophil granule major basic protein (MBP). Preincubating basophil-containing mononuclear cells with 0.01 to 10 ng/ml IL-3 or IL-5 for 15 min at 37 degrees
Ryan M Fryer et al.
American journal of physiology. Heart and circulatory physiology, 290(6), H2554-H2559 (2006-01-10)
The net contribution of endothelin type A (ET(A)) and type B (ET(B)) receptors in blood pressure regulation in humans and experimental animals, including the conscious mouse, remains undefined. Thus we assessed the role of ET(A) and ET(B) receptors in the
G K Oriji et al.
Prostaglandins, leukotrienes, and essential fatty acids, 56(2), 151-156 (1997-02-01)
Chronic treatment with the immunosuppressive drug, Cyclosporine A (CsA), is associated with increased intracellular calcium in vascular smooth muscle cells, which may cause vasoconstriction and/or activate phospholipase A2. We used rat aortic rings to investigate the role of protein kinase
M Adamczyk et al.
Steroids, 62(6), 462-467 (1997-06-01)
6-Oxoestradiol (2) was protected as its bis[(2-trimethylsilylethoxy)methyl] ether (4) and converted to the corresponding oxime (4). The oxime (4) on reduction with zinc in ethanol afforded the bis-SEM ether of 6-alpha-aminoestradiol (5) in 96% epimeric excess. Subsequently, 5 was hydrolyzed
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