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Michael Haustein et al.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 251(5), 1389-1398 (2013-01-01)
To assess the effect of acetazolamide (AZ) on different ocular vascular beds. In a prospective study, 32 healthy volunteers (16 male, 16 female) with a mean age of 23.9 ± 3.3 years (20-39 years) were included. Before and after intravenous administration of
Lāsma Ivanova et al.
Cancer chemotherapy and pharmacology, 75(2), 235-246 (2014-11-26)
Carbonic anhydrase IX (CAIX) is a hypoxia-inducible enzyme with extracellular catalytic domain that is overexpressed in a variety of cancers including breast cancer and plays a crucial role in maintaining favourable intracellular pH and reducing extracellular pH. The purpose of
Domenico De Rasmo et al.
Biochimica et biophysica acta, 1853(1), 183-191 (2014-11-21)
In mammalian cells the nuclear-encoded subunits of complex I are imported into mitochondria, where they are assembled with mt-DNA encoded subunits in the complex, or exchanged with pre-existing copies in the complex. The present work shows that in fibroblast cultures
Emma V Low et al.
BMJ (Clinical research ed.), 345, e6779-e6779 (2012-10-20)
To assess the efficacy of three different daily doses of acetazolamide in the prevention of acute mountain sickness and to determine the lowest effective dose. Systematic review and meta-analysis. Medline and Embase along with a hand search of selected bibliographies.
Julie Czupryna et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 56(3), 483-488 (2015-02-07)
We report the design, testing, and in vivo application of pH-sensitive contrast agents designed specifically for Cerenkov imaging. Radioisotopes used for PET emit photons via Cerenkov radiation. The multispectral emission of Cerenkov radiation allows for selective bandwidth quenching, in which
SCN4A-associated hypokalemic periodic paralysis merits a trial of acetazolamide.
S L Venance et al.
Neurology, 63(10), 1977-1977 (2004-11-24)
Acetazolamide for the prophylaxis of acute mountain sickness.
Chris Imray
BMJ (Clinical research ed.), 345, e7077-e7077 (2012-11-02)
Syed Ali et al.
Seminars in ophthalmology, 28(1), 50-54 (2012-11-21)
A 63 year old woman was referred to the retina clinic after her vision failed to improve in her left eye after cataract surgery. X-linked retinoschisis was diagnosed in the patient after her retina exam revealed an area of retinoschisis
Romualdo Malagola et al.
Drug design, development and therapy, 7, 33-36 (2013-02-05)
Idiosyncratic reactions to a large number of drugs have been reported to cause choroidal detachment and secondary angle-closure glaucoma (ACG). We report a case of bilateral acute ACG and peculiar choroidal effusion following administration of oral acetazolamide immediately after cataract
Neil D Ritchie et al.
Journal of travel medicine, 19(5), 298-307 (2012-09-05)
Acetazolamide has been reported to be effective in the prevention of acute mountain sickness (AMS). Our aim was to conduct a systematic review of randomized, placebo-controlled trials of acetazolamide in the prevention of AMS. Studies were identified by searching the
Quiz page January 2013: sudden deafness in a patient treated with long-term hemodialysis.
Billy T Hour et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 61(1), A29-A31 (2012-12-19)
Lucie Nováková et al.
Analytica chimica acta, 853, 637-646 (2014-12-04)
The conditions for the analysis of selected doping substances by UHPSFC-MS/MS were optimized to ensure suitable peak shapes and maximized MS responses. A representative mixture of 31 acidic and basic doping agents was analyzed, in both ESI+ and ESI- modes.
Radiology quiz case 1: suspected arachnoid cyst of the right cerebellopontineangle.
Malika Atmakuri et al.
JAMA otolaryngology-- head & neck surgery, 139(5), 519-521 (2013-05-18)
Shoko M Yamada et al.
Clinical nuclear medicine, 38(9), 671-676 (2013-07-03)
Good outcome of shunt surgery for idiopathic normal pressure hydrocephalus (iNPH) patients are highly dependent on accurate preoperative assessments. Acetazolamide ethylcysteinate-dimer-single photon emission computer tomography (SPECT) was applied to iNPH patients for more exact preoperative evaluation. Sixty-five patients were categorized
Bengt Kayser et al.
High altitude medicine & biology, 13(2), 82-92 (2012-06-26)
Acetazolamide is used to prevent acute mountain sickness (AMS). We assessed efficacy and harm of acetazolamide for the prevention of AMS, and tested for dose-responsiveness. We systematically searched electronic databases (until April 2011) for randomized trials comparing acetazolamide with placebo
Deborah S Schumacher et al.
Chest, 146(5), 1226-1236 (2014-07-06)
Sleep-disturbed breathing (SDB) is common in patients with precapillary pulmonary hypertension (PH). Nocturnal oxygen therapy (NOT) and acetazolamide improve SDB in patients with PH, and NOT improves exercise capacity. We investigated the effect of NOT and acetazolamide on nocturnal cardiac
Caroline Zanotto et al.
Brain research, 1491, 14-22 (2012-11-13)
Aquaporin-4 (AQP-4) is the principal brain water channel and is predominantly expressed in astrocytes suggesting its dynamic involvement in water homeostasis in brain tissue. Due to the co-localization of AQP-4 and inward rectifier K(+) channels Kir 4.1, a functional coupling
A S Vagal et al.
AJNR. American journal of neuroradiology, 30(5), 876-884 (2009-02-28)
The acetazolamide (ACZ) challenge test is a useful clinical tool and a reliable predictor of critically reduced perfusion. In patients with chronic steno-occlusive disease, the ability to maintain normal cerebral blood flow by reducing vascular resistance secondary to autoregulatory vasodilation
Deborah E A Lockhart et al.
FEBS letters, 588(17), 3282-3290 (2014-07-27)
A limited therapeutic arsenal against increasing clinical disease due to Aspergillus spp. necessitates urgent characterisation of new antifungal targets. Here we describe the discovery of novel, low micromolar chemical inhibitors of Aspergillus fumigatus family 18 plant-type chitinase A1 (AfChiA1) by
Karim Farid et al.
Nuclear medicine communications, 33(6), 571-580 (2012-04-13)
Cerebrovascular disease is recognized as a common cause of cognitive impairment and dementia, alone or coexisting with other neurodegenerative diseases, mostly Alzheimer's disease. Vascular cognitive impairment (VCI) is a part of the heterogenous disorders group related to cerebral vessel disease.
W L Olson
Southern medical journal, 92(2), 228-232 (1999-03-11)
Patients with episodic or paroxysmal movements or postures often are thought to have hysteric or psychosomatic illnesses. Kinesigenic (movement-induced) posturing similarly is usually misinterpreted. This case is notable because of the presence of symptoms of two distinct diseases with similar
Tyler M Basting et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(2), 527-543 (2015-01-16)
In conscious mammals, hypoxia or hypercapnia stimulates breathing while theoretically exerting opposite effects on central respiratory chemoreceptors (CRCs). We tested this theory by examining how hypoxia and hypercapnia change the activity of the retrotrapezoid nucleus (RTN), a putative CRC and
Intracranial complications of idiopathic intracranial hypertension.
Linda Yang et al.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 47(6), e53-e55 (2012-12-12)
Acute high-altitude illnesses.
Jean-Paul Richalet et al.
The New England journal of medicine, 369(17), 1664-1665 (2013-10-25)
G Settakis et al.
European journal of neurology, 10(6), 609-620 (2003-12-04)
Pathologic processes affecting the brain vessels may damage cerebral vasodilatory capacity. Early detection of cerebral dysfunction plays an important role in the prevention of cerebrovascular diseases. In recent decades acetazolamide (AZ) has frequently been used for this purpose. In the
Profound alkalemia secondary to gastric outlet obstruction and acute renal insufficiency.
David P Betten et al.
The American journal of emergency medicine, 31(2), 444-444 (2013-02-15)
Acute high-altitude illnesses.
Peter Bärtsch et al.
The New England journal of medicine, 369(17), 1666-1667 (2013-10-25)
Lucie Nováková et al.
Analytica chimica acta, 853, 647-659 (2014-12-04)
The potential and applicability of UHPSFC-MS/MS for anti-doping screening in urine samples were tested for the first time. For this purpose, a group of 110 doping agents with diverse physicochemical properties was analyzed using two separation techniques, namely UHPLC-MS/MS and
[Anuric acute renal failure due to acetazolamide].
R López-Menchero et al.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 26(6), 755-756 (2007-01-18)
Yong-Hong Huang et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 34(3), 1743-1751 (2013-02-26)
Aquaporin 5 (AQP5) promotes the progression and invasion of several cancers, but its role in the tumorigenesis of human gastric carcinoma (GC) has not been clearly defined. Here, we investigated the potential functions of AQP5 in the proliferation and migration
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