Sung-Wuk Jang et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(8), 3876-3881 (2010-02-06)
Brain-derived neurotrophic factor (BDNF) is a cognate ligand for the TrkB receptor. BDNF and serotonin often function in a cooperative manner to regulate neuronal plasticity, neurogenesis, and neuronal survival. Here we show that NAS (N-acetylserotonin) swiftly activates TrkB in a