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Juan Ignacio Felice et al.
Metabolism: clinical and experimental, 63(2), 296-305 (2013-12-21)
The aims of this study were: first, to evaluate the possible effects of a fructose rich diet (FRD)-induced metabolic syndrome (MS) on different aspects of long bone histomorphometry in young male rats; second, to investigate the effects of this diet
V O Kryliuk
Klinichna khirurhiia, (2)(2), 67-70 (2013-05-28)
The peculiarities of course of endogenous intoxication (EI) in severe combined abdominal trauma were studied up in experiment. There was established, that in the laboratory animals, to whom the blood loss compensation was done, using colloid-hyperosmolar solution, the El severity
Ante Muljacić et al.
Collegium antropologicum, 37(4), 1275-1283 (2014-03-13)
Alkaline phosphatase (ALP) and bone-specific alkaline phosphatase (S-bone ALP) activities may serve as markers of the course and rate of bone healing after sustained fractures. The aim of this study was to examine whether the assessment of S-bone ALP as
Jian Zhou et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(11), 1783-1788 (2013-09-10)
To compare the effect of icariin and genistein in the osteogenic differentiation of rat bone marrow stromal cells (rBMSC). Rat marrow stromal cells were seperated in vitro, and the optimal concentration of genisten and icriin were screened. Genistein and icariin
Rogerio B Kato et al.
Journal of cellular physiology, 229(11), 1690-1696 (2014-03-13)
The aim of this study was to investigate if chemically produced nanotopography on titanium (Ti) surface induces osteoblast differentiation of cultured human bone marrow mesenchymal stem cells (hMSCs) by regulating the expression of microRNAs (miRs). It was demonstrated that Ti
Pallab Datta et al.
Journal of biomedical nanotechnology, 9(5), 870-879 (2013-06-28)
Most polymeric nanofibers used for bone tissue engineering lack adequate functional groups for bioactivity. This study explores the potential of nanofibers of phosphate functionalized derivative of chitosan-N-methylene phosphonic chitosan (NMPC) for bone tissue engineering. Nanofibers were fabricated by electrospinning of
Tadayuki Iida et al.
Hiroshima journal of medical sciences, 62(3), 49-53 (2013-11-28)
The relationship of bone mineral density (BMD) and bone metabolic markers in women is an interesting field of research. In this study, we aimed to clarify the relationship of body weight, bone metabolic markers and BMD. The subjects were 72
Primo N Lara et al.
Journal of the National Cancer Institute, 106(4), dju013-dju013 (2014-02-26)
Prior studies suggest that elevated markers of bone turnover are prognostic for poor survival in castration-resistant prostate cancer (CRPC). The predictive role of these markers relative to bone-targeted therapy is unknown. We prospectively evaluated the prognostic and predictive value of
Kohji Miura et al.
Clinical calcium, 23(12), 1789-1794 (2013-12-03)
Skeletal dysplasia is the term which represents disorders including growth and differentiation of bone, cartilage and ligament. A lot of diseases are included, and new disorders have been added. However, the therapy of most bone diseases is less well-established. Achondroplasia
J W Kim et al.
Journal of dental research, 93(5), 483-489 (2014-02-27)
ATF6 is an endoplasmic reticulum (ER) membrane-bound transcription factor that regulates various cellular functions. The purpose of this study was to investigate the role of ATF6 in odontoblast differentiation. Rat tooth germs were isolated, changes in gene expression were evaluated
Hexabromocyclododecane and polychlorinated biphenyls increase resistance of hepatocellular carcinoma cells to cisplatin through the phosphatidylinositol 3-kinase/protein kinase B pathway.
An J, Wang X, Guo P, et al.
Toxicology Letters, 229(1), 265-272 (2014)
T Guo et al.
Journal of dental research, 93(12), 1290-1295 (2014-08-21)
In previous studies, fluorapatite (FA) crystal-coated surfaces have been shown to stimulate the differentiation and mineralization of human dental pulp stem cells (DPSCs) in two-dimensional cell culture. However, whether the FA surface can recapitulate these properties in three-dimensional culture is
Gulvahid Shaikh et al.
Clinical laboratory, 60(3), 491-494 (2014-04-05)
Wilson's disease presenting as fulminant hepatic failure is a rare presentation that carries a high morbidity and mortality. We report a young patient who developed fulminant hepatic failure as the initial manifestation of Wilson's disease. Virtually undetectable serum alkaline phosphatase
Johad F Khoury et al.
The Israel Medical Association journal : IMAJ, 16(1), 26-32 (2014-03-01)
In osteosarcoma the histological response, measured by the percentage of tumor necrosis, constitutes one of the most significant predictive factors, with better survival in patients whose tumor necrosis is > or = 90%. To determine if the decrease rate of
Li Cui et al.
Neurobiology of aging, 30(6), 903-909 (2007-11-03)
Aging was associated with increased oxidation of DNA, RNA, and lipids in the cerebellum of male rats. DNA and lipid oxidation was reduced by lifelong (94 weeks) voluntary exercise on a running wheel. A reduction in cerebellar lipid oxidation, but
Naomi Ofer et al.
The Journal of biological chemistry, 288(16), 11287-11293 (2013-03-09)
Protein degradation via prokaryotic ubiquitin-like protein (Pup) tagging is conserved in bacteria belonging to the phyla Actinobacteria and Nitrospira. The physiological role of this novel proteolytic pathway is not yet clear, although in Mycobacterium tuberculosis, the world's most threatening bacterial
Ryosuke Yamaguchi et al.
Rheumatology (Oxford, England), 53(12), 2191-2195 (2014-06-25)
The aim of this study was to compare the levels of bone and cartilage metabolism markers in the synovial fluid of the hip joint between patients with secondary OA due to osteonecrosis of the femoral head (ONFH), rapidly destructive arthrosis
Isabel Moller et al.
Glycoconjugate journal, 25(1), 37-48 (2007-07-17)
Antibody-producing hybridoma cell lines were created following immunisation with a crude extract of cell wall polymers from the plant Arabidopsis thaliana. In order to rapidly screen the specificities of individual monoclonal antibodies (mAbs), their binding to microarrays containing 50 cell
Alexandra M Roch et al.
Annals of surgery, 260(4), 680-688 (2014-09-10)
As such, the natural history of MPD-involved IPMN is poorly understood. The high-risk of malignancy associated with main pancreatic duct (MPD)-involved intraductal papillary mucinous neoplasm (IPMN) has been established by surgical series. The International Consensus Guidelines recommend surgical resection of
G U Mohangi et al.
SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 67(7), 354-358 (2013-08-21)
Demineralised bone matrix (DBM) is an allograft material widely used as a bone filler and bone graft substitute. DBM contains bone morphogenetic proteins (BMPs), which induce and regulate bone formation during embryogenesis and in postnatal life. To investigate the osteoinductivity
Gregory R Sondag et al.
Journal of cellular physiology, 229(7), 955-966 (2013-11-23)
Osteoactivin (OA) is a novel osteogenic factor important for osteoblast differentiation and function. Previous studies showed that OA stimulates matrix mineralization and transcription of osteoblast specific genes required for differentiation. OA plays a role in wound healing and its expression
Evaluation of parathyroid levels and bone densitometry after cinacalcet treatment in severe primary hyperparathyroidism.
C Ogrin
Minerva endocrinologica, 38(3), 337-338 (2013-10-16)
K T Shalumon et al.
Journal of biomedical nanotechnology, 9(3), 430-440 (2013-04-30)
A biomimetic scaffold which can very closely mimic the extracellular matrix of the bone was fabricated by incorporating nano-bioceramic particles such as nano bioglass (nBG) and nano hydroxyapatite (nHAp) within electrospun nanofibrous scaffold. A comparative study between nHAp incorporated poly(caprolactone)
Xia Kang et al.
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 27(9), 1122-1127 (2013-11-28)
To investigate the role of micro RNA-451 (miRNA-451) in promoting the osteogenesis of mesenchymal stem cells (MSCs) by targeting regulatory calcium binding protein 39 (CAB39). pMIR-report and pRL-TK vectors were selected to identify the relationship between miRNA-451 and CAB39 by
S R Pidruchna
Klinichna khirurhiia, (3)(3), 59-62 (2013-05-31)
In recent years there are intensively studied the role of hepatocytic affection in the complications progress in trauma of various genesis, including the multiple and combined. Positive correcting impact of lyophilized xenoimplants on the hepatic markers activity was demonstrated in
Yuki Matsushita et al.
The Journal of biological chemistry, 288(27), 19973-19985 (2013-05-09)
CCN3, a member of the CCN protein family, inhibits osteoblast differentiation in vitro. However, the role of CCN3 in bone regeneration has not been well elucidated. In this study, we investigated the role of CCN3 in bone regeneration. We identified
M R Giuca et al.
European journal of paediatric dentistry : official journal of European Academy of Paediatric Dentistry, 14(3), 175-180 (2013-12-04)
The aim of the present investigation was to analyse cephalometric skeletal structures and hormonal and enzymatic parameters in young obese subjects in comparison with those of normal weight subjects. The whole sample consisted of 50 Caucasian patients (28 males and
Roman Szabo et al.
The American journal of pathology, 174(6), 2015-2022 (2009-04-25)
Hepatocyte growth factor activator inhibitor-1 (HAI)-1 is an epithelial Kunitz-type transmembrane serine protease inhibitor that is encoded by the SPINT1 gene. HAI-1 displays potent inhibitory activity toward a large number of trypsin-like serine proteases. HAI-1 was recently shown to play
Clare Wykes et al.
Annals of hematology, 93(12), 2051-2056 (2014-07-02)
Vitamin D deficiency is common in sickle cell anaemia (SCA, HbSS), although its significance and optimal means of correction are unknown. We conducted an audit to assess the clinical significance of 25-hydroxy vitamin D (25-OHD) deficiency in children with SCA
I V Zverinskiĭ et al.
Biomeditsinskaia khimiia, 59(1), 90-96 (2013-05-09)
On the eighth day after ligation of the common bile duct in rats a significant increase in the serum content of total lipids, cholesterol bilirubin and ALT, alkaline phosphatase, and gamma-glutamyltransferase was observed. In the microsomal fraction there was a
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